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Protein

Putative fluoride ion transporter CrcB 2

Gene

crcB2

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Important for reducing fluoride concentration in the cell, thus reducing its toxicity.UniRule annotation

GO - Molecular functioni

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Putative fluoride ion transporter CrcB 2UniRule annotation
Gene namesi
Name:crcB2UniRule annotation
Ordered Locus Names:BMEI0634
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000000419 Componenti: Chromosome I

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei4 – 24HelicalUniRule annotationAdd BLAST21
Transmembranei35 – 55HelicalUniRule annotationAdd BLAST21
Transmembranei67 – 87HelicalUniRule annotationAdd BLAST21
Transmembranei96 – 116HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001100721 – 270Putative fluoride ion transporter CrcB 2Add BLAST270

Interactioni

Protein-protein interaction databases

STRINGi224914.BAWG_2610

Structurei

3D structure databases

ProteinModelPortaliQ8YI11
SMRiQ8YI11
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CrcB (TC 9.B.71) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105X2M Bacteria
COG0239 LUCA
COG3439 LUCA
HOGENOMiHOG000289132
OMAiIIGMGMM

Family and domain databases

Gene3Di3.30.310.70, 1 hit
HAMAPiMF_00454 CrcB, 1 hit
InterProiView protein in InterPro
IPR003691 CrcB
IPR005180 DUF302
IPR035923 TT1751-like_sf
PANTHERiPTHR28259 PTHR28259, 1 hit
PfamiView protein in Pfam
PF02537 CRCB, 1 hit
PF03625 DUF302, 1 hit
SUPFAMiSSF103247 SSF103247, 1 hit

Sequencei

Sequence statusi: Complete.

Q8YI11-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLDIIILVVI GGAFGAMTRE FIMLMVPPLT DGFPLDILVA NVVACFLLGT
60 70 80 90 100
VTALYARKIH SRDVHTIIGT GMMGGVSTFS SFAYGSVVLA SASVSAFLIA
110 120 130 140 150
AAYVTVSVVA GYVAVLAGMK FGEKSADILH RYPPMASIID SGLVTVESRH
160 170 180 190 200
SVAETIERVA AKAKSMGMNV FTRVDHGAGA KEAGLGLPPT ELIIFGNPQN
210 220 230 240 250
GTVLMQDKRT IGLDLPIRAL AWEDGSGKVW LTVNDPAWLA QRHSLGLSSD
260 270
VAIKAMVTGT GTVTKYAAGD
Length:270
Mass (Da):28,298
Last modified:March 1, 2002 - v1
Checksum:iA5E8739B22B5E1B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA Translation: AAL51815.1
PIRiAD3331
RefSeqiWP_004683989.1, NZ_GG703780.1

Genome annotation databases

EnsemblBacteriaiAAL51815; AAL51815; BMEI0634
GeneIDi29593419
KEGGibme:BMEI0634
bmel:DK63_792
PATRICifig|224914.52.peg.829

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA Translation: AAL51815.1
PIRiAD3331
RefSeqiWP_004683989.1, NZ_GG703780.1

3D structure databases

ProteinModelPortaliQ8YI11
SMRiQ8YI11
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224914.BAWG_2610

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL51815; AAL51815; BMEI0634
GeneIDi29593419
KEGGibme:BMEI0634
bmel:DK63_792
PATRICifig|224914.52.peg.829

Phylogenomic databases

eggNOGiENOG4105X2M Bacteria
COG0239 LUCA
COG3439 LUCA
HOGENOMiHOG000289132
OMAiIIGMGMM

Family and domain databases

Gene3Di3.30.310.70, 1 hit
HAMAPiMF_00454 CrcB, 1 hit
InterProiView protein in InterPro
IPR003691 CrcB
IPR005180 DUF302
IPR035923 TT1751-like_sf
PANTHERiPTHR28259 PTHR28259, 1 hit
PfamiView protein in Pfam
PF02537 CRCB, 1 hit
PF03625 DUF302, 1 hit
SUPFAMiSSF103247 SSF103247, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCRCB2_BRUME
AccessioniPrimary (citable) accession number: Q8YI11
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: March 1, 2002
Last modified: October 10, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
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Main funding by: National Institutes of Health

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