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Protein

50S ribosomal protein L2

Gene

rplB

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciBMEL224914:G1FZL-813-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L2UniRule annotation
Gene namesi
Name:rplBUniRule annotation
Ordered Locus Names:BMEI0760
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000000419 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001295371 – 27750S ribosomal protein L2Add BLAST277

Proteomic databases

PRIDEiQ8YHN7

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.UniRule annotation

Protein-protein interaction databases

STRINGi224914.BAWG_2732

Structurei

3D structure databases

ProteinModelPortaliQ8YHN7
SMRiQ8YHN7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uL2 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CFD Bacteria
COG0090 LUCA
HOGENOMiHOG000232982
KOiK02886
OMAiHGYIKGV

Family and domain databases

Gene3Di2.30.30.30, 1 hit
4.10.950.10, 1 hit
HAMAPiMF_01320_B Ribosomal_L2_B, 1 hit
InterProiView protein in InterPro
IPR012340 NA-bd_OB-fold
IPR022666 Rbsml_prot_L2_RNA-bd_dom
IPR014722 Rib_L2_dom2
IPR002171 Ribosomal_L2
IPR005880 Ribosomal_L2_bac/org-type
IPR022669 Ribosomal_L2_C
IPR022671 Ribosomal_L2_CS
IPR014726 Ribosomal_L2_dom3
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR13691 PTHR13691, 1 hit
PfamiView protein in Pfam
PF00181 Ribosomal_L2, 1 hit
PF03947 Ribosomal_L2_C, 1 hit
PIRSFiPIRSF002158 Ribosomal_L2, 1 hit
SMARTiView protein in SMART
SM01383 Ribosomal_L2, 1 hit
SM01382 Ribosomal_L2_C, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR01171 rplB_bact, 1 hit
PROSITEiView protein in PROSITE
PS00467 RIBOSOMAL_L2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8YHN7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALKHFNPIT PGQRQLVIVD RSELYKGKPV KSLTEGLSKK GGRNNTGRIT
60 70 80 90 100
VRFQGGGHKR SYRFIDFKRR KLDVVGTVER LEYDPNRTAF IALIRYTDGE
110 120 130 140 150
LAYILAPQRL AVGDQVVAGN SVDVKPGNAM PLSSMPVGTI IHNVELMPGK
160 170 180 190 200
GGQIARSAGT YAQLVGRDQG MAILRLNSGE QRLVSGACFA SVGAVSNPDH
210 220 230 240 250
GNINDGKAGR SVWRGKRPHV RGVAMNPVDH PHGGGEGRTS GGRHPVTPWG
260 270
KPTKGKKTRS NKATDKFIMR SRHQRKK
Length:277
Mass (Da):30,171
Last modified:March 1, 2002 - v1
Checksum:i4F3B6E30A3FC8059
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA Translation: AAL51941.1
PIRiAB3347
RefSeqiWP_004683925.1, NZ_GG703780.1

Genome annotation databases

EnsemblBacteriaiAAL51941; AAL51941; BMEI0760
GeneIDi29593563
KEGGibme:BMEI0760
bmel:DK63_662
PATRICifig|224914.52.peg.693

Similar proteinsi

Entry informationi

Entry nameiRL2_BRUME
AccessioniPrimary (citable) accession number: Q8YHN7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: March 1, 2002
Last modified: May 23, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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