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Protein
Submitted name:

Hydroxymethylglutaryl-CoA lyase

Gene

BMEI1926

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi14CalciumCombined sources1
Metal bindingi205Calcium; via tele nitrogenCombined sources1
Metal bindingi207Calcium; via tele nitrogenCombined sources1
Metal bindingi247CalciumCombined sources1

GO - Molecular functioni

Keywordsi

Molecular functionLyaseImported
LigandCalciumCombined sources, Metal-bindingCombined sources

Enzyme and pathway databases

BioCyciBMEL224914:G1FZL-2059-MONOMER
BRENDAi4.1.3.4 995

Names & Taxonomyi

Protein namesi
Submitted name:
Hydroxymethylglutaryl-CoA lyaseImported (EC:4.1.3.4Imported)
Gene namesi
Ordered Locus Names:BMEI1926Imported
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)Imported
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000000419 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

Interactioni

Protein-protein interaction databases

STRINGi224914.BAWG_0314

Structurei

3D structure databases

ProteinModelPortaliQ8YEF2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 272Pyruvate carboxyltransferaseInterPro annotationAdd BLAST268

Phylogenomic databases

eggNOGiENOG4105CBH Bacteria
COG0119 LUCA
HOGENOMiHOG000219757
KOiK01640
OMAiFGGCPMA

Family and domain databases

Gene3Di3.20.20.70, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR027167 HMG-CoA_lyase
IPR000891 PYR_CT
PANTHERiPTHR42738:SF4 PTHR42738:SF4, 1 hit
PfamiView protein in Pfam
PF00682 HMGL-like, 1 hit
PROSITEiView protein in PROSITE
PS50991 PYR_CT, 1 hit

Sequencei

Sequence statusi: Complete.

Q8YEF2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEHVEIVEM AARDGLQNEK RFVPTADKIA LINRLSDCGY ARIEATSFVS
60 70 80 90 100
PKWVPQLADS REVMAGIRRA DGVRYSVLVP NMKGYEAAAA AHADEIAVFI
110 120 130 140 150
SASEGFSKAN INCTIAESIE RLSPVIGAAI NDGLAIRGYV SCVVECPYDG
160 170 180 190 200
PVTPQAVASV TEQLFSLGCH EVSLGDTIGR GTPDTVAAML DAVLAIAPAH
210 220 230 240 250
SLAGHYHDTG GRALDNIRVS LEKGLRVFDA SVGGLGGCPF APGAKGNVDT
260 270 280
VAVVEMLHEM GFETGLDLDR LRSAGLFTQA LRQDKAA
Length:287
Mass (Da):30,253
Last modified:March 1, 2002 - v1
Checksum:i0F0762A723BD9295
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA Translation: AAL53107.1
PIRiAH3492
RefSeqiWP_004684602.1, NZ_GG703778.1

Genome annotation databases

EnsemblBacteriaiAAL53107; AAL53107; BMEI1926
GeneIDi29594807
KEGGibme:BMEI1926
bmel:DK63_1562
PATRICifig|224914.52.peg.1648

Similar proteinsi

Entry informationi

Entry nameiQ8YEF2_BRUME
AccessioniPrimary (citable) accession number: Q8YEF2
Secondary accession number(s): D0B482
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: July 18, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported

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