Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable acid stress chaperone HdeA

Gene

hdeA

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Required for optimal acid stress protection. Exhibits a chaperone-like activity only at low pH by suppressing non-specifically the aggregation of denaturated periplasmic proteins.UniRule annotation

GO - Biological processi

Keywordsi

Molecular functionChaperone

Names & Taxonomyi

Protein namesi
Recommended name:
Probable acid stress chaperone HdeAUniRule annotation
Gene namesi
Name:hdeAUniRule annotation
Ordered Locus Names:BMEII0906
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000000419 Componenti: Chromosome II

Subcellular locationi

  • Periplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26UniRule annotationAdd BLAST26
ChainiPRO_000033863427 – 114Probable acid stress chaperone HdeAAdd BLAST88

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi46 ↔ 94UniRule annotation

Keywords - PTMi

Disulfide bond

Interactioni

Protein-protein interaction databases

STRINGi224914.BAWG_1681

Structurei

3D structure databases

ProteinModelPortaliQ8YBJ4
SMRiQ8YBJ4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HdeA family.UniRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG41060V2 Bacteria
ENOG41128BT LUCA
HOGENOMiHOG000125826
KOiK19777

Family and domain databases

Gene3Di1.10.890.10, 1 hit
HAMAPiMF_00946 HdeA, 1 hit
InterProiView protein in InterPro
IPR024972 HdeA
IPR038303 HdeA/HdeB_sf
IPR036831 HdeA_sf
IPR010486 HNS-dep_expression_A/B
PfamiView protein in Pfam
PF06411 HdeA, 1 hit
PIRSFiPIRSF009564 HNS-dep_expression_A, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD065392 HNS-dep_expression_A, 1 hit
SUPFAMiSSF47752 SSF47752, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8YBJ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKALFNKNT ALAAVAILAL SGGAMAESAK THKTDMAKKK VSELTCEDFN
60 70 80 90 100
GLEESFKPTV VGWVVGFNKK GKEEDAVIDV DGIETVTPAI IEACKQEPKA
110
SFWKKAEAEL KKVF
Length:114
Mass (Da):12,332
Last modified:June 10, 2008 - v2
Checksum:i0B5A298253466C53
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY518304 Genomic DNA Translation: AAR98497.1
AE008918 Genomic DNA Translation: AAL54148.1
PIRiAI3622
RefSeqiWP_002966248.1, NZ_GG703779.1

Genome annotation databases

EnsemblBacteriaiAAL54148; AAL54148; BMEII0906
GeneIDi29596047
KEGGibme:BMEII0906
bmel:DK63_2344
PATRICifig|224914.52.peg.2455

Similar proteinsi

Entry informationi

Entry nameiHDEA_BRUME
AccessioniPrimary (citable) accession number: Q8YBJ4
Secondary accession number(s): Q6R2J7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: June 10, 2008
Last modified: March 28, 2018
This is version 86 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health