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Protein

FAD assembly factor SdhE

Gene

sdhE

Organism
Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.By similarity

Keywordsi

Molecular functionChaperone

Names & Taxonomyi

Protein namesi
Recommended name:
FAD assembly factor SdhE
Gene namesi
Name:sdhE
Ordered Locus Names:RSc1992
ORF Names:RS03560
OrganismiRalstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)
Taxonomic identifieri267608 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia
Proteomesi
  • UP000001436 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002144181 – 95FAD assembly factor SdhEAdd BLAST95

Interactioni

Protein-protein interaction databases

STRINGi267608.RSc1992

Structurei

3D structure databases

ProteinModelPortaliQ8XXX1
SMRiQ8XXX1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SdhE FAD assembly factor family.Curated

Phylogenomic databases

eggNOGiENOG41060IS Bacteria
COG2938 LUCA
HOGENOMiHOG000160701
KOiK09159
OMAiKRARLRW
OrthoDBiPOG091H04A8

Family and domain databases

Gene3Di1.10.150.250, 1 hit
InterProiView protein in InterPro
IPR005631 SDH
IPR036714 SDH_sf
PfamiView protein in Pfam
PF03937 Sdh5, 1 hit
SUPFAMiSSF109910 SSF109910, 1 hit

Sequencei

Sequence statusi: Complete.

Q8XXX1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTAVNTSTFS HQSDPHRRAR LRWRARRGLL ENDIIVERFF NRYETELSDD
60 70 80 90
DVGALTQLFE LPDNDLMDLL LARKEPEGAL DVPSVRHVLS LLRAV
Length:95
Mass (Da):10,987
Last modified:March 1, 2002 - v1
Checksum:i3966A39C96BA2AE0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL646052 Genomic DNA Translation: CAD15694.1
RefSeqiWP_011001928.1, NC_003295.1

Genome annotation databases

EnsemblBacteriaiCAD15694; CAD15694; RSc1992
GeneIDi1220832
KEGGirso:RSc1992

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL646052 Genomic DNA Translation: CAD15694.1
RefSeqiWP_011001928.1, NC_003295.1

3D structure databases

ProteinModelPortaliQ8XXX1
SMRiQ8XXX1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi267608.RSc1992

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAD15694; CAD15694; RSc1992
GeneIDi1220832
KEGGirso:RSc1992

Phylogenomic databases

eggNOGiENOG41060IS Bacteria
COG2938 LUCA
HOGENOMiHOG000160701
KOiK09159
OMAiKRARLRW
OrthoDBiPOG091H04A8

Family and domain databases

Gene3Di1.10.150.250, 1 hit
InterProiView protein in InterPro
IPR005631 SDH
IPR036714 SDH_sf
PfamiView protein in Pfam
PF03937 Sdh5, 1 hit
SUPFAMiSSF109910 SSF109910, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSDHE_RALSO
AccessioniPrimary (citable) accession number: Q8XXX1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: March 1, 2002
Last modified: May 23, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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