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Protein
Submitted name:

Exo-alpha-sialidase

Gene

nanJ

Organism
Clostridium perfringens (strain 13 / Type A)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi68Calcium; via carbonyl oxygenCombined sources1
Metal bindingi71CalciumCombined sources1
Metal bindingi73Calcium; via carbonyl oxygenCombined sources1
Metal bindingi76CalciumCombined sources1
Binding sitei110GalactoseCombined sources1
Metal bindingi174Calcium; via carbonyl oxygenCombined sources1

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumCombined sources, Metal-bindingCombined sources

Protein family/group databases

CAZyiCBM32 Carbohydrate-Binding Module Family 32
CBM40 Carbohydrate-Binding Module Family 40
GH33 Glycoside Hydrolase Family 33

Names & Taxonomyi

Protein namesi
Submitted name:
Exo-alpha-sialidaseImported
Gene namesi
Name:nanJImported
OrganismiClostridium perfringens (strain 13 / Type A)Imported
Taxonomic identifieri195102 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000000818 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_500431744627 – 1173Sequence analysisAdd BLAST1147

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
nagHP268312EBI-15722735,EBI-15722600

Protein-protein interaction databases

DIPiDIP-46267N
IntActiQ8XMY5, 3 interactors

Structurei

3D structure databases

ProteinModelPortaliQ8XMY5
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8XMY5

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 181F5/8 type CInterPro annotationAdd BLAST146
Domaini1088 – 1173Fibronectin type-IIIInterPro annotationAdd BLAST86

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni79 – 82Galactose bindingCombined sources4

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

HOGENOMiHOG000120093
KOiK01186
OMAiYEIHAIN
OrthoDBiPOG091H0EBR

Family and domain databases

CDDicd00063 FN3, 1 hit
Gene3Di2.60.120.260, 1 hit
2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR008965 CBM2/CBM3_carb-bd_dom_sf
IPR013320 ConA-like_dom_sf
IPR000421 FA58C
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR008979 Galactose-bd-like_sf
IPR004124 Glyco_hydro_33_N
IPR013783 Ig-like_fold
IPR011040 Sialidase
IPR026856 Sialidase_fam
IPR021984 Sialidase_pen_C
IPR036278 Sialidase_sf
PANTHERiPTHR10628 PTHR10628, 1 hit
PfamiView protein in Pfam
PF13088 BNR_2, 1 hit
PF00754 F5_F8_type_C, 1 hit
PF02973 Sialidase, 1 hit
PF12135 Sialidase_penC, 1 hit
SMARTiView protein in SMART
SM00060 FN3, 1 hit
SUPFAMiSSF49265 SSF49265, 1 hit
SSF49384 SSF49384, 1 hit
SSF49785 SSF49785, 1 hit
SSF49899 SSF49899, 1 hit
SSF50939 SSF50939, 2 hits
PROSITEiView protein in PROSITE
PS50022 FA58C_3, 1 hit
PS50853 FN3, 1 hit

Sequencei

Sequence statusi: Complete.

Q8XMY5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSKKIIATL VASLVISNMG GYLVKANPNV NHKAVIIEDR QAIIETAIPQ
60 70 80 90 100
SEMTASATSE EGQDPASSAI DGNINTMWHT KWNGSDALPQ SLSVNLGKAR
110 120 130 140 150
KVSSIAITPR TSGNNGFITK YEIHAINNGV ETLVAEGTWE ENNLVKTVTF
160 170 180 190 200
DSPIDAEEIK ITAIQGVGGF ASIAELNVYE IKGEVDEIAN YGNLKITKEE
210 220 230 240 250
ERLNITGDLE KFSSLDEGTI VTRFNMNDTS IQSLIGLSDG NKANNYFSLY
260 270 280 290 300
VSGGKVGYEL RRQEGNGDFN VHHSADVTFN KGINTLALKI EKGVGAKIFL
310 320 330 340 350
NGSLVKTVSD PNIKFLNAIN LNSGFIGKTD RANGYNEYLF RGNIDFMNIY
360 370 380 390 400
DKPVSDNYLL RKTGETKAPS EDSLLPDDVY KTQPVELFYP GYLESRGYRI
410 420 430 440 450
PALETTKKGT VLASIDVRNN GDHDAPNNNI DVGIRRKEVN GEWEEGKVIL
460 470 480 490 500
DYPGKSAAID TSLMSATIEE NGIEKERIFL IVTHFPEGYG FPNTEGGSGY
510 520 530 540 550
KEIDGKYYFI LKDAQNNEYT VREDGIVYNS EGNQTDYVMK NDKTLIQNGE
560 570 580 590 600
EVGNALLSNS PLKAVGTAHI EMIYSDDDGK TWSEPEDLNP GLKKEWMKFF
610 620 630 640 650
GTAPGKGIQI KNGEHKGRLV FPIYYTNQNN FQSSAVIYSD DFGETWKLGE
660 670 680 690 700
SPIDTASVSS ETVSSGTQLT ECQVVEMPNG QLKLFMRNTG SYTKIATSFD
710 720 730 740 750
GGATWHDEVP EDTSLREPYC QLSVINYSGK INGKDAIIFS NPDASSRVNG
760 770 780 790 800
SVKVGLINEN GTYDNGEPRY EFDWIYNKTV KPGSFAYSCL TELPDGNLGL
810 820 830 840 850
FYEGEGAGRM AYTEFDLNYL KFNASEDSPS ASVQSIEVLD EDLAYNSGEE
860 870 880 890 900
VSIKVNFNQL VSIIGDRKIT LDIGGVDVPL NMVNYEGKSS AIFKGTIPEG
910 920 930 940 950
INQGNYEIKL KENNTLELNT VYNKVSTFNG LDNTGINVQI GELKTTVGNS
960 970 980 990 1000
TIKVNDEVQV GSAFEAILGI EGLNGDTEVY SAEYLFEYNV EAFILNEITS
1010 1020 1030 1040 1050
FNDSLFVKSK EVEPGKVRIL VASLGNEIEK DSDLVKVNLT PKISSELEVL
1060 1070 1080 1090 1100
GLTTALVGAG DGNTHDLELS SKEVKINEEA SGEIVVNPVQ NFEIPEINKK
1110 1120 1130 1140 1150
NVKLTWNAPI TTEGLEGYVI YKDGKKLSEV PAESTEFVVS KLNRHTIYNF
1160 1170
KVAAKYSNGE LSAKESKTIR TAR
Length:1,173
Mass (Da):128,782
Last modified:March 1, 2002 - v1
Checksum:i276A1E0A43A788CA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000016 Genomic DNA Translation: BAB80259.1
RefSeqiWP_011009886.1, NC_003366.1

Genome annotation databases

EnsemblBacteriaiBAB80259; BAB80259; BAB80259
KEGGicpe:CPE0553

Similar proteinsi

Entry informationi

Entry nameiQ8XMY5_CLOPE
AccessioniPrimary (citable) accession number: Q8XMY5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: July 18, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

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