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Protein
Submitted name:

Cd2+/Zn2+-exporting ATPase

Gene

zntA

Organism
Escherichia coli O157:H7
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi59PROSITE-ProRule annotation1
Metal bindingi62PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotation
LigandMetal-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cd2+/Zn2+-exporting ATPaseImported
Submitted name:
Zinc-transporting ATPaseImported
Gene namesi
Name:zntAImported
Ordered Locus Names:Z4843Imported
ORF Names:ECpv15279_4271Imported, ECs_4318Imported
OrganismiEscherichia coli O157:H7Imported
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei150 – 168HelicalUniRule annotationAdd BLAST19
Transmembranei353 – 374HelicalUniRule annotationAdd BLAST22
Transmembranei380 – 404HelicalUniRule annotationAdd BLAST25
Transmembranei686 – 702HelicalUniRule annotationAdd BLAST17

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi155864.Z4843

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 113HMAInterPro annotationAdd BLAST65

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiENOG4105C59 Bacteria
COG2217 LUCA
HOGENOMiHOG000250399
KOiK01534
OMAiAVVAKCC

Family and domain databases

CDDicd00371 HMA, 1 hit
Gene3Di3.40.1110.10, 1 hit
3.40.50.1000, 2 hits
InterProiView protein in InterPro
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR017969 Heavy-metal-associated_CS
IPR006121 HMA_dom
IPR036163 HMA_dom_sf
IPR027256 P-typ_ATPase_IB
IPR001757 P_typ_ATPase
PfamiView protein in Pfam
PF00403 HMA, 1 hit
PRINTSiPR00120 HATPASE
SUPFAMiSSF55008 SSF55008, 1 hit
SSF56784 SSF56784, 2 hits
SSF81653 SSF81653, 1 hit
SSF81665 SSF81665, 3 hits
TIGRFAMsiTIGR01525 ATPase-IB_hvy, 1 hit
TIGR01494 ATPase_P-type, 1 hit
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit
PS01047 HMA_1, 1 hit
PS50846 HMA_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8X6Q4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSTPDNHGKK APQFAAFKPL TTVQNANDCC CDGACSSTPT LSENVSGTRY
60 70 80 90 100
SWKVSGMDCA ACARKVENAV RQLAGVNQVQ VLFATEKLVV DADNDIRAQV
110 120 130 140 150
ESAVQKAGYS LRDEQAADEP QASRLKENLP LITLIVMMAI SWGLEQFNHP
160 170 180 190 200
FGQLAFIATT LVGLYPIARQ ALRLIKSGSY FAIETLMSVA AIGALFIGAT
210 220 230 240 250
AEAAMVLLLF LIGERLEGWA ASRARQGVSA LMALKPETAT RLRNGEREEV
260 270 280 290 300
AINSLRPGDV IEVAAGGRLP ADGKLLSPFA SFDESALTGE SIPVERATGD
310 320 330 340 350
KVPAGATSVD RLVTLEVLSE PGASAIDRIL KLIEEAEERR APIERFIDRF
360 370 380 390 400
SRIYTPAIMA VALLVTLVPP LLFATSWQEW IYKGLTLLLI GCPCALVIST
410 420 430 440 450
PAAITSGLAA AARRGALIKG GAALEQLGRV TQVAFDKTGT LTVGKPRVTA
460 470 480 490 500
IHPATGISES ELLTLAAAVE QGATHPLAQA IVREAQVAAL AIPAAESQRA
510 520 530 540 550
LVGSGIEAQV NGERVLICAA GKHPADAFAG LINELESAGQ TVVLVVRNDD
560 570 580 590 600
VLGIIALQDT LRADAATAIS ELNALGVKGV ILTGDNPRAA AAIAGELGLE
610 620 630 640 650
FKAGLLPEDK VKAVTELNQH APLAMVGDGI NDAPAMKAAA IGIAMGSGTD
660 670 680 690 700
VALETADAAL THNHLRGLVQ MIELARATHA NIRQNITIAL GLKGIFLVTT
710 720 730
LLGMTGLWLA VLADTGATVL VTANALRLLR RR
Length:732
Mass (Da):76,724
Last modified:March 1, 2002 - v1
Checksum:iB4E6BE217B6B11FA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA Translation: AAG58578.1
BA000007 Genomic DNA Translation: BAB37741.1
AP018488 Genomic DNA Translation: BBC52580.1
PIRiF86014
F91168
RefSeqiNP_312345.1, NC_002695.1
WP_000106562.1, NZ_NOKN01000002.1

Genome annotation databases

EnsemblBacteriaiAAG58578; AAG58578; Z4843
BAB37741; BAB37741; BAB37741
GeneIDi915826
KEGGiece:Z4843
ecs:ECs4318
PATRICifig|386585.9.peg.4511

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA Translation: AAG58578.1
BA000007 Genomic DNA Translation: BAB37741.1
AP018488 Genomic DNA Translation: BBC52580.1
PIRiF86014
F91168
RefSeqiNP_312345.1, NC_002695.1
WP_000106562.1, NZ_NOKN01000002.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi155864.Z4843

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG58578; AAG58578; Z4843
BAB37741; BAB37741; BAB37741
GeneIDi915826
KEGGiece:Z4843
ecs:ECs4318
PATRICifig|386585.9.peg.4511

Phylogenomic databases

eggNOGiENOG4105C59 Bacteria
COG2217 LUCA
HOGENOMiHOG000250399
KOiK01534
OMAiAVVAKCC

Family and domain databases

CDDicd00371 HMA, 1 hit
Gene3Di3.40.1110.10, 1 hit
3.40.50.1000, 2 hits
InterProiView protein in InterPro
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR017969 Heavy-metal-associated_CS
IPR006121 HMA_dom
IPR036163 HMA_dom_sf
IPR027256 P-typ_ATPase_IB
IPR001757 P_typ_ATPase
PfamiView protein in Pfam
PF00403 HMA, 1 hit
PRINTSiPR00120 HATPASE
SUPFAMiSSF55008 SSF55008, 1 hit
SSF56784 SSF56784, 2 hits
SSF81653 SSF81653, 1 hit
SSF81665 SSF81665, 3 hits
TIGRFAMsiTIGR01525 ATPase-IB_hvy, 1 hit
TIGR01494 ATPase_P-type, 1 hit
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit
PS01047 HMA_1, 1 hit
PS50846 HMA_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ8X6Q4_ECO57
AccessioniPrimary (citable) accession number: Q8X6Q4
Secondary accession number(s): A0A0H3JHC1, Q7AA67
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: October 10, 2018
This is version 149 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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