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Protein

Contactin-associated protein-like 5

Gene

CNTNAP5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell adhesion

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Contactin-associated protein-like 5
Alternative name(s):
Cell recognition molecule Caspr5
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CNTNAP5
Synonyms:CASPR5
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000155052.14

Human Gene Nomenclature Database

More...
HGNCi
HGNC:18748 CNTNAP5

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610519 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8WYK1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini25 – 1237ExtracellularSequence analysisAdd BLAST1213
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1238 – 1258HelicalSequence analysisAdd BLAST21
Topological domaini1259 – 1306CytoplasmicSequence analysisAdd BLAST48

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
129684

Open Targets

More...
OpenTargetsi
ENSG00000155052

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134898715

Polymorphism and mutation databases

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74716461

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 24Sequence analysisAdd BLAST24
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000031737725 – 1306Contactin-associated protein-like 5Add BLAST1282

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi30 ↔ 174By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi282N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi329 ↔ 360By similarity
Glycosylationi355N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi496N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi512 ↔ 544By similarity
Disulfide bondi550 ↔ 561By similarity
Disulfide bondi555 ↔ 570By similarity
Glycosylationi571N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi572 ↔ 582By similarity
Glycosylationi622N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi929 ↔ 956By similarity
Disulfide bondi960 ↔ 973By similarity
Disulfide bondi967 ↔ 982By similarity
Disulfide bondi984 ↔ 994By similarity
Disulfide bondi1164 ↔ 1199By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8WYK1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8WYK1

PeptideAtlas

More...
PeptideAtlasi
Q8WYK1

PRoteomics IDEntifications database

More...
PRIDEi
Q8WYK1

ProteomicsDB human proteome resource

More...
ProteomicsDBi
75163

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8WYK1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8WYK1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000155052 Expressed in 59 organ(s), highest expression level in corpus callosum

CleanEx database of gene expression profiles

More...
CleanExi
HS_CNTNAP5

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8WYK1 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA069095
HPA069356

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000399013

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q8WYK1

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini30 – 174F5/8 type CPROSITE-ProRule annotationAdd BLAST145
Domaini180 – 360Laminin G-like 1PROSITE-ProRule annotationAdd BLAST181
Domaini367 – 544Laminin G-like 2PROSITE-ProRule annotationAdd BLAST178
Domaini546 – 583EGF-like 1PROSITE-ProRule annotationAdd BLAST38
Domaini584 – 790Fibrinogen C-terminalPROSITE-ProRule annotationAdd BLAST207
Domaini791 – 956Laminin G-like 3PROSITE-ProRule annotationAdd BLAST166
Domaini957 – 995EGF-like 2PROSITE-ProRule annotationAdd BLAST39
Domaini1013 – 1199Laminin G-like 4PROSITE-ProRule annotationAdd BLAST187

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi44 – 47Poly-Ser4

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the neurexin family.Curated

Keywords - Domaini

EGF-like domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3516 Eukaryota
ENOG410XPHG LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160532

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG057718

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8WYK1

Identification of Orthologs from Complete Genome Data

More...
OMAi
GVEPITH

Database of Orthologous Groups

More...
OrthoDBi
EOG091G00LF

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8WYK1

TreeFam database of animal gene trees

More...
TreeFami
TF321823

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00057 FA58C, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.260, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028874 Caspr5
IPR013320 ConA-like_dom_sf
IPR000742 EGF-like_dom
IPR000421 FA58C
IPR036056 Fibrinogen-like_C
IPR002181 Fibrinogen_a/b/g_C_dom
IPR008979 Galactose-bd-like_sf
IPR001791 Laminin_G

The PANTHER Classification System

More...
PANTHERi
PTHR43925:SF4 PTHR43925:SF4, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00754 F5_F8_type_C, 1 hit
PF02210 Laminin_G_2, 4 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00181 EGF, 2 hits
SM00231 FA58C, 1 hit
SM00282 LamG, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49785 SSF49785, 1 hit
SSF49899 SSF49899, 4 hits
SSF56496 SSF56496, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50026 EGF_3, 2 hits
PS01286 FA58C_2, 1 hit
PS50022 FA58C_3, 1 hit
PS51406 FIBRINOGEN_C_2, 1 hit
PS50025 LAM_G_DOMAIN, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q8WYK1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDSLPRLTSV LTLLFSGLWH LGLTATNYNC DDPLASLLSP MAFSSSSDLT
60 70 80 90 100
GTHSPAQLNW RVGTGGWSPA DSNAQQWLQM DLGNRVEITA VATQGRYGSS
110 120 130 140 150
DWVTSYSLMF SDTGRNWKQY KQEDSIWTFA GNMNADSVVH HKLLHSVRAR
160 170 180 190 200
FVRFVPLEWN PSGKIGMRVE VYGCSYKSDV ADFDGRSSLL YRFNQKLMST
210 220 230 240 250
LKDVISLKFK SMQGDGVLFH GEGQRGDHIT LELQKGRLAL HLNLGDSKAR
260 270 280 290 300
LSSSLPSATL GSLLDDQHWH SVLIERVGKQ VNFTVDKHTQ HFRTKGETDA
310 320 330 340 350
LDIDYELSFG GIPVPGKPGT FLKKNFHGCI ENLYYNGVNI IDLAKRRKHQ
360 370 380 390 400
IYTGNVTFSC SEPQIVPITF VNSSGSYLLL PGTPQIDGLS VSFQFRTWNK
410 420 430 440 450
DGLLLSTELS EGSGTLLLSL EGGILRLVIQ KMTERVAEIL TGSNLNDGLW
460 470 480 490 500
HSVSINARRN RITLTLDDEA APPAPDSTWV QIYSGNSYYF GGCPDNLTDS
510 520 530 540 550
QCLNPIKAFQ GCMRLIFIDN QPKDLISVQQ GSLGNFSDLH IDLCSIKDRC
560 570 580 590 600
LPNYCEHGGS CSQSWTTFYC NCSDTSYTGA TCHNSIYEQS CEVYRHQGNT
610 620 630 640 650
AGFFYIDSDG SGPLGPLQVY CNITEDKIWT SVQHNNTELT RVRGANPEKP
660 670 680 690 700
YAMALDYGGS MEQLEAVIDG SEHCEQEVAY HCRRSRLLNT PDGTPFTWWI
710 720 730 740 750
GRSNERHPYW GGSPPGVQQC ECGLDESCLD IQHFCNCDAD KDEWTNDTGF
760 770 780 790 800
LSFKDHLPVT QIVITDTDRS NSEAAWRIGP LRCYGDRRFW NAVSFYTEAS
810 820 830 840 850
YLHFPTFHAE FSADISFFFK TTALSGVFLE NLGIKDFIRL EISSPSEITF
860 870 880 890 900
AIDVGNGPVE LVVQSPSLLN DNQWHYVRAE RNLKETSLQV DNLPRSTRET
910 920 930 940 950
SEEGHFRLQL NSQLFVGGTS SRQKGFLGCI RSLHLNGQKM DLEERAKVTS
960 970 980 990 1000
GVRPGCPGHC SSYGSICHNG GKCVEKHNGY LCDCTNSPYE GPFCKKEVSA
1010 1020 1030 1040 1050
VFEAGTSVTY MFQEPYPVTK NISLSSSAIY TDSAPSKENI ALSFVTTQAP
1060 1070 1080 1090 1100
SLLLFINSSS QDFVVVLLCK NGSLQVRYHL NKEETHVFTI DADNFANRRM
1110 1120 1130 1140 1150
HHLKINREGR ELTIQMDQQL RLSYNFSPEV EFRVIRSLTL GKVTENLGLD
1160 1170 1180 1190 1200
SEVAKANAMG FAGCMSSVQY NHIAPLKAAL RHATVAPVTV HGTLTESSCG
1210 1220 1230 1240 1250
FMVDSDVNAV TTVHSSSDPF GKTDEREPLT NAVRSDSAVI GGVIAVVIFI
1260 1270 1280 1290 1300
IFCIIGIMTR FLYQHKQSHR TSQMKEKEYP ENLDSSFRNE IDLQNTVSEC

KREYFI
Length:1,306
Mass (Da):145,623
Last modified:March 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i132F8B1D9200C68E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti353T → TV in BAB71205 (PubMed:14702039).Curated1
Sequence conflicti449L → P in BAB71205 (PubMed:14702039).Curated1
Sequence conflicti957 – 962PGHCSS → SIKKLK in BAB71205 (PubMed:14702039).Curated6

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_038518452S → L. Corresponds to variant dbSNP:rs17727261Ensembl.1
Natural variantiVAR_0385191195T → M. Corresponds to variant dbSNP:rs34165507Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB077881 mRNA Translation: BAB83897.1
AC019105 Genomic DNA Translation: AAY14716.1
AC019159 Genomic DNA Translation: AAX88894.1
AC074362 Genomic DNA Translation: AAX81997.1
AC079154 Genomic DNA Translation: AAY15042.1
AC097715 Genomic DNA Translation: AAY24250.1
AC104648 Genomic DNA Translation: AAX88904.1
CH471103 Genomic DNA Translation: EAW95266.1
AK056528 mRNA Translation: BAB71205.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS46401.1

NCBI Reference Sequences

More...
RefSeqi
NP_570129.1, NM_130773.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.660653

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000431078; ENSP00000399013; ENSG00000155052

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
129684

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:129684

UCSC genome browser

More...
UCSCi
uc002tno.5 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB077881 mRNA Translation: BAB83897.1
AC019105 Genomic DNA Translation: AAY14716.1
AC019159 Genomic DNA Translation: AAX88894.1
AC074362 Genomic DNA Translation: AAX81997.1
AC079154 Genomic DNA Translation: AAY15042.1
AC097715 Genomic DNA Translation: AAY24250.1
AC104648 Genomic DNA Translation: AAX88904.1
CH471103 Genomic DNA Translation: EAW95266.1
AK056528 mRNA Translation: BAB71205.1
CCDSiCCDS46401.1
RefSeqiNP_570129.1, NM_130773.3
UniGeneiHs.660653

3D structure databases

ProteinModelPortaliQ8WYK1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000399013

PTM databases

iPTMnetiQ8WYK1
PhosphoSitePlusiQ8WYK1

Polymorphism and mutation databases

DMDMi74716461

Proteomic databases

EPDiQ8WYK1
PaxDbiQ8WYK1
PeptideAtlasiQ8WYK1
PRIDEiQ8WYK1
ProteomicsDBi75163

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
129684
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000431078; ENSP00000399013; ENSG00000155052
GeneIDi129684
KEGGihsa:129684
UCSCiuc002tno.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
129684
DisGeNETi129684
EuPathDBiHostDB:ENSG00000155052.14

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CNTNAP5
HGNCiHGNC:18748 CNTNAP5
HPAiHPA069095
HPA069356
MIMi610519 gene
neXtProtiNX_Q8WYK1
OpenTargetsiENSG00000155052
PharmGKBiPA134898715

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3516 Eukaryota
ENOG410XPHG LUCA
GeneTreeiENSGT00940000160532
HOVERGENiHBG057718
InParanoidiQ8WYK1
OMAiGVEPITH
OrthoDBiEOG091G00LF
PhylomeDBiQ8WYK1
TreeFamiTF321823

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CNTNAP5 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
129684

Protein Ontology

More...
PROi
PR:Q8WYK1

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
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Gene expression databases

BgeeiENSG00000155052 Expressed in 59 organ(s), highest expression level in corpus callosum
CleanExiHS_CNTNAP5
GenevisibleiQ8WYK1 HS

Family and domain databases

CDDicd00057 FA58C, 1 hit
Gene3Di2.60.120.260, 1 hit
InterProiView protein in InterPro
IPR028874 Caspr5
IPR013320 ConA-like_dom_sf
IPR000742 EGF-like_dom
IPR000421 FA58C
IPR036056 Fibrinogen-like_C
IPR002181 Fibrinogen_a/b/g_C_dom
IPR008979 Galactose-bd-like_sf
IPR001791 Laminin_G
PANTHERiPTHR43925:SF4 PTHR43925:SF4, 1 hit
PfamiView protein in Pfam
PF00754 F5_F8_type_C, 1 hit
PF02210 Laminin_G_2, 4 hits
SMARTiView protein in SMART
SM00181 EGF, 2 hits
SM00231 FA58C, 1 hit
SM00282 LamG, 4 hits
SUPFAMiSSF49785 SSF49785, 1 hit
SSF49899 SSF49899, 4 hits
SSF56496 SSF56496, 1 hit
PROSITEiView protein in PROSITE
PS50026 EGF_3, 2 hits
PS01286 FA58C_2, 1 hit
PS50022 FA58C_3, 1 hit
PS51406 FIBRINOGEN_C_2, 1 hit
PS50025 LAM_G_DOMAIN, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCNTP5_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8WYK1
Secondary accession number(s): Q4ZFW2
, Q4ZG21, Q53R09, Q53RX1, Q53SG3, Q584P3, Q96MS7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: March 1, 2002
Last modified: December 5, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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