Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 129 (10 Feb 2021)
Sequence version 1 (01 Mar 2002)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Down syndrome cell adhesion molecule

Gene

DSCAM

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Down syndrome cell adhesion moleculeImported
Submitted name:
Down syndrome cell adhesion molecule splice variantImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DSCAMImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 21

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:3039, DSCAM

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000171587.14

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1347 – 1368HelicalSequence analysisAdd BLAST22

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000171587

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q8WY19

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
75118

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000171587, Expressed in endometrium epithelium and 73 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8WY19, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8WY19

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 57Ig-likeInterPro annotationAdd BLAST57
Domaini65 – 153Ig-likeInterPro annotationAdd BLAST89
Domaini159 – 252Ig-likeInterPro annotationAdd BLAST94
Domaini256 – 344Ig-likeInterPro annotationAdd BLAST89
Domaini348 – 437Ig-likeInterPro annotationAdd BLAST90
Domaini442 – 535Ig-likeInterPro annotationAdd BLAST94
Domaini539 – 635Ig-likeInterPro annotationAdd BLAST97
Domaini637 – 734Fibronectin type-IIIInterPro annotationAdd BLAST98
Domaini739 – 838Fibronectin type-IIIInterPro annotationAdd BLAST100
Domaini843 – 939Fibronectin type-IIIInterPro annotationAdd BLAST97
Domaini943 – 1037Fibronectin type-IIIInterPro annotationAdd BLAST95
Domaini1037 – 1129Ig-likeInterPro annotationAdd BLAST93
Domaini1131 – 1225Fibronectin type-IIIInterPro annotationAdd BLAST95
Domaini1226 – 1327Fibronectin type-IIIInterPro annotationAdd BLAST102

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1470 – 1561DisorderedSequence analysisAdd BLAST92
Regioni1607 – 1634DisorderedSequence analysisAdd BLAST28
Regioni1684 – 1746DisorderedSequence analysisAdd BLAST63

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1477 – 1519PolarSequence analysisAdd BLAST43
Compositional biasi1534 – 1561PolarSequence analysisAdd BLAST28
Compositional biasi1607 – 1621PolarSequence analysisAdd BLAST15
Compositional biasi1684 – 1702PolarSequence analysisAdd BLAST19
Compositional biasi1716 – 1730PolarSequence analysisAdd BLAST15

Keywords - Domaini

Immunoglobulin domainARBA annotation, RepeatARBA annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154678

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00063, FN3, 6 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 14 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR043204, Basigin-like
IPR033027, DSCAM_metazoan
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR013098, Ig_I-set
IPR003599, Ig_sub
IPR003598, Ig_sub2

The PANTHER Classification System

More...
PANTHERi
PTHR10075, PTHR10075, 1 hit
PTHR10075:SF51, PTHR10075:SF51, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00041, fn3, 5 hits
PF07679, I-set, 5 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00060, FN3, 6 hits
SM00409, IG, 8 hits
SM00408, IGc2, 8 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48726, SSF48726, 8 hits
SSF49265, SSF49265, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50853, FN3, 6 hits
PS50835, IG_LIKE, 8 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q8WY19-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
LGHPEPDYRW LKDNMPLELS GRFQKTVTGL LIENIRPSDS GSYVCEVSNR
60 70 80 90 100
YGTAKVIGRL YVKQPLKATI SPRKVKSSVG SQVSLSCSVT GTEDQELSWY
110 120 130 140 150
RNGEILNPGK NVRITGINHE NLIMDHMVKS DGGAYQCFVR KDKLSAQDYV
160 170 180 190 200
QVVLEDGTPK IISAFSEKVV SPAEPVSLMC NVKGTPLPTI TWTLDDDPIL
210 220 230 240 250
KGGSHRISQM ITSEGNVVSY LNISSSQVRD GGVYRCTANN SAGVVLYQAR
260 270 280 290 300
INVRGPASIR PMKNITAIAG RDTYIHCRVI GYPYYSIKWY KNSNLLPFNH
310 320 330 340 350
RQVAFENNGT LKLSDVQKEV DEGEYTCNVL VQPQLSTSQS VHVTVKVPPF
360 370 380 390 400
IQPFEFPRFS IGQRVFIPCV VVSGDLPITI TWQKDGRPIP GSLGVTIDNI
410 420 430 440 450
DFTSSLRISN LSLMHNGNYT CIARNEAAAV EHQSQLIVRV PPKFVVQPRD
460 470 480 490 500
QDGIYGKAVI LNCSAEGYPV PTIVWKFSKG AGVPQFQPIA LNGRIQVLSN
510 520 530 540 550
GSLLIKHVVE EDSGYYLCKV SNDVGADVSK SMYLTVKIPA MITSYPNTTL
560 570 580 590 600
ATQGQKKEMS CTAHGEKPII VRWEKEDRII NPEMARYLVS TKEVGEEVIS
610 620 630 640 650
TLQILPTVRE DSGFFSCHAI NSYGEDRGII QLTVQEPPDP PEIEIKDVKA
660 670 680 690 700
RTITLRWTMG FDGNSPITGY DIECKNKSDS WDSAQRTKDV SPQLNSATII
710 720 730 740 750
DIHPSSTYSI RMYAKNRIGK SEPSNELTIT ADEAAPDGPP QEVHLEPISS
760 770 780 790 800
QSIRVTWKAP KKHLQNGIIR GYQIGYREYS TGGNFQFNII SVDTSGDSEV
810 820 830 840 850
YTLDNLNKFT QYGLVVQACN RAGTGPSSQE IITTTLEDVP SYPPENVQAI
860 870 880 890 900
ATSPESISIS WSTLSKEALN GILQGFRVIY WANLMDGELG EIKNITTTQP
910 920 930 940 950
SLELDGLEKY TNYSIQVLAF TRAGDGVRSE QIFTRTKEDV PGPPAGVKAA
960 970 980 990 1000
AASASMVFVS WLPPLKLNGI IRKYTVFCSH PYPTVISEFE ASPDSFSYRI
1010 1020 1030 1040 1050
PNLSRNRQYS VWVVAVTSAG RGNSSEIITV EPLAKAPARI LTFSGTVTTP
1060 1070 1080 1090 1100
WMKDIVLPCK AVGDPSPAVK WMKDSNGTPS LVTIDGRRSI FSNGSFIIRT
1110 1120 1130 1140 1150
VKAEDSGYYS CIANNNWGSD EIILNLQVQV PPDQPRLTVS KTTSSSITLS
1160 1170 1180 1190 1200
WLPGDNGGSS IRGYILQYSE DNSEQWGSFP ISPSERSYRL ENLKCGTWYK
1210 1220 1230 1240 1250
FTLTAQNGVG PGRISEIIEA KTLGKEPQFS KEQELFASIN TTRVRLNLIG
1260 1270 1280 1290 1300
WNDGGCPITS FTLEYRPFGT TVWTTAQRTS LSKSYILYDL QEATWYELQM
1310 1320 1330 1340 1350
RVCNSAGCAE KQANFATLNY DGSTIPPLIK SVVQNEEGLT TNEGLKMLVT
1360 1370 1380 1390 1400
ISCILVGVLL LFVLLLVVRR RRREQRLKRL RDAKSLAEML MSKNTRTSDT
1410 1420 1430 1440 1450
LSKQQQTLRM HIDIPRAQLL IEERDTMETI DDRSTVLLTD ADFGEAAKQK
1460 1470 1480 1490 1500
SLTVTHTVHY QSVSQATGPL VDVSDARPGT NPTTRRNAKA GPTARNRYAS
1510 1520 1530 1540 1550
QWTLNRPHPT ISAHTLTTDW RLPTPRAAGS VDKESDSYSV SPSQDTDRAR
1560 1570 1580 1590 1600
SSMVSTESAS STYEELARAY EHAKMEEQLR HAKFTITECF ISDTSSEQLT
1610 1620 1630 1640 1650
AGTNEYTDSL TSSTPSESGI CRFTASPPKP QDGGRVMNMA VPKAHRPGGP
1660 1670 1680 1690 1700
GTSRDLSLGQ ACLEPQKSRT LKRPTVLEPI PMEAASSASS TREGQSWQPG
1710 1720 1730 1740
AVATLPQREG AELGQAAKMS SSQESLLDSR GHLKGNNPYA KSYTLV
Length:1,746
Mass (Da):192,496
Last modified:March 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iABB8BB9B86AECC32
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O60469DSCAM_HUMAN
Down syndrome cell adhesion molecul...
DSCAM
2,012Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WUI7A0A087WUI7_HUMAN
Down syndrome cell adhesion molecul...
DSCAM
1,847Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF042090 Genomic DNA No translation available.
AF042091 Genomic DNA No translation available.
AF064862 Genomic DNA No translation available.
AF064863 Genomic DNA No translation available.
AF064865 Genomic DNA No translation available.
KF457309 Genomic DNA No translation available.
KF457311 Genomic DNA No translation available.
KF457321 Genomic DNA No translation available.
AF289030 mRNA Translation: AAL56711.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000404019; ENSP00000385342; ENSG00000171587

UCSC genome browser

More...
UCSCi
uc062agq.1, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF042090 Genomic DNA No translation available.
AF042091 Genomic DNA No translation available.
AF064862 Genomic DNA No translation available.
AF064863 Genomic DNA No translation available.
AF064865 Genomic DNA No translation available.
KF457309 Genomic DNA No translation available.
KF457311 Genomic DNA No translation available.
KF457321 Genomic DNA No translation available.
AF289030 mRNA Translation: AAL56711.1

3D structure databases

SMRiQ8WY19
ModBaseiSearch...

Proteomic databases

PRIDEiQ8WY19
ProteomicsDBi75118

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
23484, 157 antibodies

Genome annotation databases

EnsembliENST00000404019; ENSP00000385342; ENSG00000171587
UCSCiuc062agq.1, human

Organism-specific databases

HGNCiHGNC:3039, DSCAM
OpenTargetsiENSG00000171587
VEuPathDBiHostDB:ENSG00000171587.14

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00940000154678

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
1826, 2 hits in 874 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
DSCAM, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
1826

Gene expression databases

BgeeiENSG00000171587, Expressed in endometrium epithelium and 73 other tissues
ExpressionAtlasiQ8WY19, baseline and differential

Family and domain databases

CDDicd00063, FN3, 6 hits
Gene3Di2.60.40.10, 14 hits
InterProiView protein in InterPro
IPR043204, Basigin-like
IPR033027, DSCAM_metazoan
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR013098, Ig_I-set
IPR003599, Ig_sub
IPR003598, Ig_sub2
PANTHERiPTHR10075, PTHR10075, 1 hit
PTHR10075:SF51, PTHR10075:SF51, 1 hit
PfamiView protein in Pfam
PF00041, fn3, 5 hits
PF07679, I-set, 5 hits
SMARTiView protein in SMART
SM00060, FN3, 6 hits
SM00409, IG, 8 hits
SM00408, IGc2, 8 hits
SUPFAMiSSF48726, SSF48726, 8 hits
SSF49265, SSF49265, 3 hits
PROSITEiView protein in PROSITE
PS50853, FN3, 6 hits
PS50835, IG_LIKE, 8 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ8WY19_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8WY19
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: February 10, 2021
This is version 129 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again