JPH3

Functionⁱ

Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH3 is brain-specific and appears to have an active role in certain neurons involved in motor coordination and memory.

GO - Molecular functionⁱ

calcium-release channel activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

calcium ion transport into cytosol
Source: BHF-UCL
Traceable author statementⁱ
- 19095005
exploration behavior Source: Ensembl
learning Source: Ensembl
locomotion Source: Ensembl
memory Source: Ensembl
neuromuscular process controlling balance Source: Ensembl
regulation of neuronal synaptic plasticity Source: Ensembl
regulation of ryanodine-sensitive calcium-release channel activity
Source: BHF-UCL
Traceable author statementⁱ
- 19095005
regulation of synaptic plasticity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Junctophilin-3 Short name: JP-3 Alternative name(s): Junctophilin type 3 Trinucleotide repeat-containing gene 22 protein
Gene namesⁱ	Name:JPH3 Synonyms:JP3, TNRC22
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 16

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000154118.12
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:14203 JPH3
MIMⁱ	605268 gene
neXtProtⁱ	NX_Q8WXH2

Topology

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Topological domainⁱ	1 – 727	CytoplasmicSequence analysisAdd BLAST		727
Transmembraneⁱ	728 – 748	Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST		21

Keywords - Cellular componentⁱ

Cell membrane, Endoplasmic reticulum, Membrane

Pathology & Biotechⁱ

Involvement in diseaseⁱ

Huntington disease-like 2 (HDL2)2 Publications

The disease is caused by mutations affecting the gene represented in this entry.

Disease descriptionHuntington disease (HD) is a neurodegenerative disorder resulting primarily from the loss of medium spiny projection neurons in the striatum, especially in the caudate nucleus, and, to a lesser extent, atrophy of mesencephalic and cortical structures. The typical clinical picture of HD combines familial adult onset chorea and subcortical dementia that usually begin during the fourth decade of life.

Organism-specific databases

DisGeNET More...DisGeNETⁱ	57338
GeneReviewsⁱ	JPH3
MalaCards human disease database More...MalaCardsⁱ	JPH3
MIMⁱ	606438 phenotype
Open Targets More...OpenTargetsⁱ	ENSG00000154118
Orphanetⁱ	98934 Huntington disease-like 2
PharmGKBⁱ	PA30000

Polymorphism and mutation databases

DMDMⁱ	27805485

DMDMⁱ

27805485

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000159850	1 – 748	Junctophilin-3Add BLAST		748

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	440	PhosphoserineBy similarity	1
Modified residueⁱ	451	PhosphothreonineBy similarity	1
Modified residueⁱ	457	PhosphoserineBy similarity	1
Modified residueⁱ	471	PhosphothreonineBy similarity	1
Modified residueⁱ	475	PhosphoserineBy similarity	1
Modified residueⁱ	506	PhosphoserineBy similarity	1
Modified residueⁱ	703	PhosphoserineBy similarity	1
Modified residueⁱ	710	PhosphoserineBy similarity	1

Keywords - PTMⁱ

Phosphoprotein

Proteomic databases

PaxDbⁱ	Q8WXH2
PeptideAtlas More...PeptideAtlasⁱ	Q8WXH2
PRIDEⁱ	Q8WXH2
ProteomicsDBⁱ	75053 75054 [Q8WXH2-2]

PTM databases

iPTMnetⁱ	Q8WXH2
PhosphoSitePlusⁱ	Q8WXH2

Expressionⁱ

Tissue specificityⁱ

Specifically expressed in brain.1 Publication

Gene expression databases

Bgeeⁱ	ENSG00000154118 Expressed in 102 organ(s), highest expression level in dorsolateral prefrontal cortex
CleanExⁱ	HS_JPH3
Genevisibleⁱ	Q8WXH2 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA076304

HPAⁱ

HPA076304

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	121492, 3 interactors
IntActⁱ	Q8WXH2, 2 interactors
STRINGⁱ	9606.ENSP00000284262

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q8WXH2
SMRⁱ	Q8WXH2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Repeatⁱ	15 – 37	MORN 1Add BLAST	23
Repeatⁱ	39 – 60	MORN 2Add BLAST	22
Repeatⁱ	61 – 82	MORN 3Add BLAST	22
Repeatⁱ	83 – 105	MORN 4Add BLAST	23
Repeatⁱ	107 – 129	MORN 5Add BLAST	23
Repeatⁱ	130 – 152	MORN 6Add BLAST	23
Repeatⁱ	288 – 310	MORN 7Add BLAST	23
Repeatⁱ	311 – 333	MORN 8Add BLAST	23

Compositional bias

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Compositional biasⁱ	4 – 143	Gly-richAdd BLAST		140
Compositional biasⁱ	366 – 416	Ala-richAdd BLAST		51

Domainⁱ

The MORN (membrane occupation and recognition nexus) repeats contribute to the plasma membrane binding, possibly by interacting with phospholipids.By similarity

Sequence similaritiesⁱ

Belongs to the junctophilin family.Curated

Keywords - Domainⁱ

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	KOG0231 Eukaryota COG4642 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00730000110639
HOGENOMⁱ	HOG000264244
HOVERGENⁱ	HBG031648
InParanoidⁱ	Q8WXH2
KEGG Orthology (KO) More...KOⁱ	K19530
OMAⁱ	KLSNYEM
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G03WX
PhylomeDBⁱ	Q8WXH2
TreeFamⁱ	TF317210

Family and domain databases

InterProⁱ	View protein in InterPro IPR017191 Junctophilin IPR003409 MORN
PANTHERⁱ	PTHR23085 PTHR23085, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02493 MORN, 8 hits
PIRSFⁱ	PIRSF037387 Junctophilin, 1 hit
SMARTⁱ	View protein in SMART SM00698 MORN, 7 hits

Sequences (2)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

Note: Additional isoforms seem to exist.

Isoform 1 (identifier: Q8WXH2-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSSGGRFNFD DGGSYCGGWE DGKAHGHGVC TGPKGQGEYT GSWSHGFEVL 
        60         70         80         90        100
GVYTWPSGNT YQGTWAQGKR HGIGLESKGK WVYKGEWTHG FKGRYGVREC 
       110        120        130        140        150
AGNGAKYEGT WSNGLQDGYG TETYSDGGTY QGQWVGGMRQ GYGVRQSVPY 
       160        170        180        190        200
GMAAVIRSPL RTSINSLRSE HTNGTALHPD ASPAVAGSPA VSRGGFVLVA 
       210        220        230        240        250
HSDSEILKSK KKGLFRRSLL SGLKLRKSES KSSLASQRSK QSSFRSEAGM 
       260        270        280        290        300
STVSSTASDI HSTISLGEAE AELAVIEDDI DATTTETYVG EWKNDKRSGF 
       310        320        330        340        350
GVSQRSDGLK YEGEWASNRR HGYGCMTFPD GTKEEGKYKQ NILVGGKRKN 
       360        370        380        390        400
LIPLRASKIR EKVDRAVEAA ERAATIAKQK AEIAASRTSH SRAKAEAALT 
       410        420        430        440        450
AAQKAQEEAR IARITAKEFS PSFQHRENGL EYQRPKRQTS CDDIEVLSTG 
       460        470        480        490        500
TPLQQESPEL YRKGTTPSDL TPDDSPLQSF PTSPAATPPP APAARNKVAH 
       510        520        530        540        550
FSRQVSVDEE RGGDIQMLLE GRAGDCARSS WGEEQAGGSR GVRSGALRGG 
       560        570        580        590        600
LLVDDFRTRG SGRKQPGNPK PRERRTESPP VFTWTSHHRA SNHSPGGSRL 
       610        620        630        640        650
LELQEEKLSN YRMEMKPLLR METHPQKRRY SKGGACRGLG DDHRPEDRGF 
       660        670        680        690        700
GVQRLRSKAQ NKENFRPASS AEPAVQKLAS LRLGGAEPRL LRWDLTFSPP 
       710        720        730        740 
QKSLPVALES DEENGDELKS STGSAPILVV MVILLNIGVA ILFINFFI

Length:748

Mass (Da):81,469

Last modified:January 17, 2003 - v2

Checksum:ⁱB88E5065FD7BCD02

GO

Isoform 2 (identifier: Q8WXH2-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
128-188: GTYQGQWVGG...PDASPAVAGS → DATAFGAEPG...DSPISTPQCT
189-748: Missing.

« Hide

        10         20         30         40         50
MSSGGRFNFD DGGSYCGGWE DGKAHGHGVC TGPKGQGEYT GSWSHGFEVL 
        60         70         80         90        100
GVYTWPSGNT YQGTWAQGKR HGIGLESKGK WVYKGEWTHG FKGRYGVREC 
       110        120        130        140        150
AGNGAKYEGT WSNGLQDGYG TETYSDGDAT AFGAEPGPEA RELPAAAAAA 
       160        170        180 
AAAAAAAAAV RWFLCREPWP ALQLPACLDS PISTPQCT

Show »

Length:188

Mass (Da):19,766

Checksum:ⁱ1B7895E8FDFB4310

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	176	A → P in BAB11983 (PubMed:10891348).Curated		1
Sequence conflictⁱ	186	A → D in BAB11983 (PubMed:10891348).Curated		1

Polymorphismⁱ

Isoform 2 length of the poly-Ala region is variable (6 to 27 CTG/CAG triplets) in the normal population and may be expanded (41 to 58 CTG/CAG triplets) in patients suffering from Huntington disease-like type 2.

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_032494	376	I → T1 PublicationCorresponds to variant dbSNP:rs17857118Ensembl.	1
Natural variantⁱVAR_032495	472	P → T1 PublicationCorresponds to variant dbSNP:rs17853660Ensembl.	1
Natural variantⁱVAR_032496	645	P → L1 PublicationCorresponds to variant dbSNP:rs17853661Ensembl.	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_002787	128 – 188	GTYQG…AVAGS → DATAFGAEPGPEARELPAAA AAAAAAAAAAAAVRWFLCRE PWPALQLPACLDSPISTPQC T in isoform 2. CuratedAdd BLAST		61
Alternative sequenceⁱVSP_002788	189 – 748	Missing in isoform 2. CuratedAdd BLAST		560

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AB042636 mRNA Translation: BAB11983.1 AB042640 Genomic DNA Translation: BAB11987.1 CH471114 Genomic DNA Translation: EAW95386.1 CH471114 Genomic DNA Translation: EAW95387.1 BC036533 mRNA Translation: AAH36533.1 AF429315 Genomic DNA Translation: AAL40941.1 BE042890 mRNA No translation available.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS10962.1 [Q8WXH2-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_065706.2, NM_020655.3 [Q8WXH2-1]
UniGeneⁱ	Hs.592068 Hs.733790

Genome annotation databases

Ensemblⁱ	ENST00000284262; ENSP00000284262; ENSG00000154118 [Q8WXH2-1]
GeneIDⁱ	57338
KEGGⁱ	hsa:57338
UCSC genome browser More...UCSCⁱ	uc002fkd.5 human [Q8WXH2-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism, Triplet repeat expansion

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q8WXH2	cDNA FLJ30924 fis, clone FEBRA2006521, highly similar to Junctophilin-3		HUMAN		423	UniRef100_Q8WXH2
cDNA FLJ58183, highly similar to Junctophilin-3		HUMAN		611

Protein	Similar proteins		Species	Score	Length	Source
Q8WXH2	cDNA FLJ30924 fis, clone FEBRA2006521, highly similar to Junctophilin-3		HUMAN		423	UniRef90_Q8WXH2
Junctophilin 3		GORGO		770
Junctophilin 3		PONAB		769
Uncharacterized protein		Cebus capucinus imitator		748
Uncharacterized protein		RHIBE		748
+25
Q8WXH2-2	Junctophilin-3		HUMAN		186	UniRef90_Q8WXH2-2
Uncharacterized protein		COLAP		184
Uncharacterized protein		MANLE		184
Junctophilin 3		PANTR		183
Uncharacterized protein		CERAT		182
+8

Protein	Similar proteins		Species	Score	Length	Source
Q8WXH2	Junctophilin-3		MOUSE		744	UniRef50_Q9ET77
junctophilin-3		Enhydra lutris kenyoni		754
junctophilin-3		ODORO		754
Junctophilin-3 (Fragment)		NEOVI		181
Uncharacterized protein		AILME		754
+142
Q8WXH2-2	Junctophilin-3		HUMAN		186	UniRef50_Q8WXH2-2
Uncharacterized protein		MANLE		184
Uncharacterized protein		COLAP		184
Junctophilin 3		PANTR		183
Uncharacterized protein		CERAT		182
+25

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AB042636 mRNA Translation: BAB11983.1 AB042640 Genomic DNA Translation: BAB11987.1 CH471114 Genomic DNA Translation: EAW95386.1 CH471114 Genomic DNA Translation: EAW95387.1 BC036533 mRNA Translation: AAH36533.1 AF429315 Genomic DNA Translation: AAL40941.1 BE042890 mRNA No translation available.
CCDSⁱ	CCDS10962.1 [Q8WXH2-1]
RefSeqⁱ	NP_065706.2, NM_020655.3 [Q8WXH2-1]
UniGeneⁱ	Hs.592068 Hs.733790

3D structure databases

ProteinModelPortalⁱ	Q8WXH2
SMRⁱ	Q8WXH2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	121492, 3 interactors
IntActⁱ	Q8WXH2, 2 interactors
STRINGⁱ	9606.ENSP00000284262

PTM databases

iPTMnetⁱ	Q8WXH2
PhosphoSitePlusⁱ	Q8WXH2

Polymorphism and mutation databases

DMDMⁱ	27805485

DMDMⁱ

27805485

Proteomic databases

PaxDbⁱ	Q8WXH2
PeptideAtlasⁱ	Q8WXH2
PRIDEⁱ	Q8WXH2
ProteomicsDBⁱ	75053 75054 [Q8WXH2-2]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	57338
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000284262; ENSP00000284262; ENSG00000154118 [Q8WXH2-1]
GeneIDⁱ	57338
KEGGⁱ	hsa:57338
UCSCⁱ	uc002fkd.5 human [Q8WXH2-1]

Organism-specific databases

CTDⁱ	57338
DisGeNETⁱ	57338
EuPathDBⁱ	HostDB:ENSG00000154118.12
GeneCardsⁱ	JPH3
GeneReviewsⁱ	JPH3
H-InvDBⁱ	HIX0013325
HGNCⁱ	HGNC:14203 JPH3
HPAⁱ	HPA076304
MalaCardsⁱ	JPH3
MIMⁱ	605268 gene 606438 phenotype
neXtProtⁱ	NX_Q8WXH2
OpenTargetsⁱ	ENSG00000154118
Orphanetⁱ	98934 Huntington disease-like 2
PharmGKBⁱ	PA30000
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG0231 Eukaryota COG4642 LUCA
GeneTreeⁱ	ENSGT00730000110639
HOGENOMⁱ	HOG000264244
HOVERGENⁱ	HBG031648
InParanoidⁱ	Q8WXH2
KOⁱ	K19530
OMAⁱ	KLSNYEM
OrthoDBⁱ	EOG091G03WX
PhylomeDBⁱ	Q8WXH2
TreeFamⁱ	TF317210

Miscellaneous databases

ChiTaRSⁱ	JPH3 human
GeneWikiⁱ	JPH3
GenomeRNAiⁱ	57338
Protein Ontology More...PROⁱ	PR:Q8WXH2
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000154118 Expressed in 102 organ(s), highest expression level in dorsolateral prefrontal cortex
CleanExⁱ	HS_JPH3
Genevisibleⁱ	Q8WXH2 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR017191 Junctophilin IPR003409 MORN
PANTHERⁱ	PTHR23085 PTHR23085, 1 hit
Pfamⁱ	View protein in Pfam PF02493 MORN, 8 hits
PIRSFⁱ	PIRSF037387 Junctophilin, 1 hit
SMARTⁱ	View protein in SMART SM00698 MORN, 7 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	JPH3_HUMAN
Accessionⁱ	Q8WXH2Primary (citable) accession number: Q8WXH2 Secondary accession number(s): D3DUN2 , Q8N471, Q9HDC3, Q9HDC4
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 17, 2003
	Last sequence update:	January 17, 2003
	Last modified:	November 7, 2018
	This is version 154 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human chromosome 16
Human chromosome 16: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

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UniProtKB - Q8WXH2 (JPH3_HUMAN)

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Junctophilin-3

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Endoplasmic reticulum

Plasma membrane

Endoplasmic reticulum

Plasma Membrane

Other locations

Topology

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Compositional bias

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ