UniProtKB - Q8WWZ7 (ABCA5_HUMAN)
Cholesterol transporter ABCA5
ABCA5
Functioni
Cholesterol efflux transporter in macrophages that is responsible for APOAI/high-density lipoproteins (HDL) formation at the plasma membrane under high cholesterol levels and participates in reverse cholesterol transport (PubMed:25125465).
May play a role in the processing of autolysosomes (By similarity).
By similarity1 PublicationCatalytic activityi
- This reaction proceeds in the forward1 Publication direction.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 514 – 521 | ATP 1PROSITE-ProRule annotation | 8 | |
Nucleotide bindingi | 1333 – 1340 | ATP 2PROSITE-ProRule annotation | 8 |
GO - Molecular functioni
- ABC-type transporter activity Source: InterPro
- ATPase-coupled transmembrane transporter activity Source: GO_Central
- ATP binding Source: UniProtKB-KW
- lipid transporter activity Source: GO_Central
GO - Biological processi
- cholesterol efflux Source: BHF-UCL
- cholesterol homeostasis Source: UniProtKB
- cholesterol metabolic process Source: UniProtKB
- high-density lipoprotein particle remodeling Source: BHF-UCL
- lipid transport Source: GO_Central
- negative regulation of macrophage derived foam cell differentiation Source: BHF-UCL
- positive regulation of reverse cholesterol transport Source: UniProtKB
- regulation of cholesterol efflux Source: UniProtKB
- reverse cholesterol transport Source: BHF-UCL
Keywordsi
Molecular function | Translocase |
Biological process | Lipid transport, Transport |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
PathwayCommonsi | Q8WWZ7 |
Reactomei | R-HSA-1369062, ABC transporters in lipid homeostasis |
SignaLinki | Q8WWZ7 |
Protein family/group databases
TCDBi | 3.A.1.211.9, the atp-binding cassette (abc) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: Cholesterol transporter ABCA5Curated (EC:7.6.2.-1 Publication)Alternative name(s): ATP-binding cassette sub-family A member 5Curated |
Gene namesi | |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:35, ABCA5 |
MIMi | 612503, gene |
neXtProti | NX_Q8WWZ7 |
VEuPathDBi | HostDB:ENSG00000154265 |
Subcellular locationi
Golgi apparatus
- Golgi apparatus membrane By similarity; Multi-pass membrane protein By similarity
Plasma membrane
- Cell membrane By similarity
Endosome
- Late endosome membrane By similarity; Multi-pass membrane protein By similarity
Lysosome
- Lysosome membrane By similarity; Multi-pass membrane protein By similarity
Note: Localized at cell membrane under high cholesterol levels.By similarity
Endosome
- late endosome Source: BHF-UCL
- late endosome membrane Source: UniProtKB-SubCell
Golgi apparatus
- Golgi apparatus Source: GO_Central
- Golgi membrane Source: UniProtKB-SubCell
Lysosome
- lysosomal membrane Source: Reactome
- lysosome Source: BHF-UCL
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
- intracellular membrane-bounded organelle Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 32 – 52 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 220 – 240 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 264 – 284 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 297 – 317 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 328 – 348 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 355 – 375 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 396 – 416 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 866 – 886 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 967 – 987 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 1021 – 1041 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 1071 – 1091 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 1102 – 1122 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 1139 – 1159 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 1169 – 1189 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 1207 – 1227 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Cell membrane, Endosome, Golgi apparatus, Lysosome, MembranePathology & Biotechi
Organism-specific databases
DisGeNETi | 23461 |
MalaCardsi | ABCA5 |
OpenTargetsi | ENSG00000154265 |
Orphaneti | 2026, Gingival fibromatosis-hypertrichosis syndrome |
PharmGKBi | PA24380 |
Miscellaneous databases
Pharosi | Q8WWZ7, Tbio |
Chemistry databases
DrugBanki | DB00864, Tacrolimus |
Genetic variation databases
BioMutai | ABCA5 |
DMDMi | 115503762 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000250669 | 1 – 1642 | Cholesterol transporter ABCA5Add BLAST | 1642 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 86 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 458 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 996 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Post-translational modificationi
Keywords - PTMi
GlycoproteinProteomic databases
EPDi | Q8WWZ7 |
jPOSTi | Q8WWZ7 |
MassIVEi | Q8WWZ7 |
MaxQBi | Q8WWZ7 |
PaxDbi | Q8WWZ7 |
PeptideAtlasi | Q8WWZ7 |
PRIDEi | Q8WWZ7 |
ProteomicsDBi | 74970 [Q8WWZ7-1] 74971 [Q8WWZ7-2] 74972 [Q8WWZ7-3] |
PTM databases
GlyGeni | Q8WWZ7, 3 sites |
iPTMneti | Q8WWZ7 |
PhosphoSitePlusi | Q8WWZ7 |
Expressioni
Tissue specificityi
Developmental stagei
Gene expression databases
Bgeei | ENSG00000154265, Expressed in intestine and 239 other tissues |
ExpressionAtlasi | Q8WWZ7, baseline and differential |
Genevisiblei | Q8WWZ7, HS |
Organism-specific databases
HPAi | ENSG00000154265, Low tissue specificity |
Interactioni
Protein-protein interaction databases
BioGRIDi | 117024, 4 interactors |
IntActi | Q8WWZ7, 3 interactors |
STRINGi | 9606.ENSP00000376443 |
Miscellaneous databases
RNActi | Q8WWZ7, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 478 – 713 | ABC transporter 1PROSITE-ProRule annotationAdd BLAST | 236 | |
Domaini | 1290 – 1533 | ABC transporter 2PROSITE-ProRule annotationAdd BLAST | 244 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1249 – 1268 | DisorderedSequence analysisAdd BLAST | 20 |
Sequence similaritiesi
Keywords - Domaini
Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0059, Eukaryota |
GeneTreei | ENSGT00940000158172 |
InParanoidi | Q8WWZ7 |
OMAi | LQLACMF |
OrthoDBi | 131191at2759 |
PhylomeDBi | Q8WWZ7 |
TreeFami | TF105192 |
Family and domain databases
Gene3Di | 3.40.50.300, 2 hits |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003439, ABC_transporter-like_ATP-bd IPR017871, ABC_transporter-like_CS IPR026082, ABCA IPR030367, ABCA5 IPR027417, P-loop_NTPase |
PANTHERi | PTHR19229, PTHR19229, 1 hit PTHR19229:SF100, PTHR19229:SF100, 1 hit |
Pfami | View protein in Pfam PF00005, ABC_tran, 2 hits |
SMARTi | View protein in SMART SM00382, AAA, 2 hits |
SUPFAMi | SSF52540, SSF52540, 2 hits |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 2 hits |
s (3+)i Sequence
Sequence statusi: Complete.
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 3 described isoforms and 8 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MSTAIREVGV WRQTRTLLLK NYLIKCRTKK SSVQEILFPL FFLFWLILIS
60 70 80 90 100
MMHPNKKYEE VPNIELNPMD KFTLSNLILG YTPVTNITSS IMQKVSTDHL
110 120 130 140 150
PDVIITEEYT NEKEMLTSSL SKPSNFVGVV FKDSMSYELR FFPDMIPVSS
160 170 180 190 200
IYMDSRAGCS KSCEAAQYWS SGFTVLQASI DAAIIQLKTN VSLWKELEST
210 220 230 240 250
KAVIMGETAV VEIDTFPRGV ILIYLVIAFS PFGYFLAIHI VAEKEKKIKE
260 270 280 290 300
FLKIMGLHDT AFWLSWVLLY TSLIFLMSLL MAVIATASLL FPQSSSIVIF
310 320 330 340 350
LLFFLYGLSS VFFALMLTPL FKKSKHVGIV EFFVTVAFGF IGLMIILIES
360 370 380 390 400
FPKSLVWLFS PFCHCTFVIG IAQVMHLEDF NEGASFSNLT AGPYPLIITI
410 420 430 440 450
IMLTLNSIFY VLLAVYLDQV IPGEFGLRRS SLYFLKPSYW SKSKRNYEEL
460 470 480 490 500
SEGNVNGNIS FSEIIEPVSS EFVGKEAIRI SGIQKTYRKK GENVEALRNL
510 520 530 540 550
SFDIYEGQIT ALLGHSGTGK STLMNILCGL CPPSDGFASI YGHRVSEIDE
560 570 580 590 600
MFEARKMIGI CPQLDIHFDV LTVEENLSIL ASIKGIPANN IIQEVQKVLL
610 620 630 640 650
DLDMQTIKDN QAKKLSGGQK RKLSLGIAVL GNPKILLLDE PTAGMDPCSR
660 670 680 690 700
HIVWNLLKYR KANRVTVFST HFMDEADILA DRKAVISQGM LKCVGSSMFL
710 720 730 740 750
KSKWGIGYRL SMYIDKYCAT ESLSSLVKQH IPGATLLQQN DQQLVYSLPF
760 770 780 790 800
KDMDKFSGLF SALDSHSNLG VISYGVSMTT LEDVFLKLEV EAEIDQADYS
810 820 830 840 850
VFTQQPLEEE MDSKSFDEME QSLLILSETK AALVSTMSLW KQQMYTIAKF
860 870 880 890 900
HFFTLKRESK SVRSVLLLLL IFFTVQIFMF LVHHSFKNAV VPIKLVPDLY
910 920 930 940 950
FLKPGDKPHK YKTSLLLQNS ADSDISDLIS FFTSQNIMVT MINDSDYVSV
960 970 980 990 1000
APHSAALNVM HSEKDYVFAA VFNSTMVYSL PILVNIISNY YLYHLNVTET
1010 1020 1030 1040 1050
IQIWSTPFFQ EITDIVFKIE LYFQAALLGI IVTAMPPYFA MENAENHKIK
1060 1070 1080 1090 1100
AYTQLKLSGL LPSAYWIGQA VVDIPLFFII LILMLGSLLA FHYGLYFYTV
1110 1120 1130 1140 1150
KFLAVVFCLI GYVPSVILFT YIASFTFKKI LNTKEFWSFI YSVAALACIA
1160 1170 1180 1190 1200
ITEITFFMGY TIATILHYAF CIIIPIYPLL GCLISFIKIS WKNVRKNVDT
1210 1220 1230 1240 1250
YNPWDRLSVA VISPYLQCVL WIFLLQYYEK KYGGRSIRKD PFFRNLSTKS
1260 1270 1280 1290 1300
KNRKLPEPPD NEDEDEDVKA ERLKVKELMG CQCCEEKPSI MVSNLHKEYD
1310 1320 1330 1340 1350
DKKDFLLSRK VKKVATKYIS FCVKKGEILG LLGPNGAGKS TIINILVGDI
1360 1370 1380 1390 1400
EPTSGQVFLG DYSSETSEDD DSLKCMGYCP QINPLWPDTT LQEHFEIYGA
1410 1420 1430 1440 1450
VKGMSASDMK EVISRITHAL DLKEHLQKTV KKLPAGIKRK LCFALSMLGN
1460 1470 1480 1490 1500
PQITLLDEPS TGMDPKAKQH MWRAIRTAFK NRKRAAILTT HYMEEAEAVC
1510 1520 1530 1540 1550
DRVAIMVSGQ LRCIGTVQHL KSKFGKGYFL EIKLKDWIEN LEVDRLQREI
1560 1570 1580 1590 1600
QYIFPNASRQ ESFSSILAYK IPKEDVQSLS QSFFKLEEAK HAFAIEEYSF
1610 1620 1630 1640
SQATLEQVFV ELTKEQEEED NSCGTLNSTL WWERTQEDRV VF
Computationally mapped potential isoform sequencesi
There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketK7EJW6 | K7EJW6_HUMAN | Cholesterol transporter ABCA5 | ABCA5 | 573 | Annotation score: | ||
Q6N017 | Q6N017_HUMAN | Cholesterol transporter ABCA5 | ABCA5 DKFZp686K07118 | 431 | Annotation score: | ||
K7EPM3 | K7EPM3_HUMAN | Cholesterol transporter ABCA5 | ABCA5 | 917 | Annotation score: | ||
K7EMV2 | K7EMV2_HUMAN | Cholesterol transporter ABCA5 | ABCA5 | 127 | Annotation score: | ||
K7ENF9 | K7ENF9_HUMAN | Cholesterol transporter ABCA5 | ABCA5 | 192 | Annotation score: | ||
A0A075B778 | A0A075B778_HUMAN | Cholesterol transporter ABCA5 | ABCA5 | 250 | Annotation score: | ||
K7EKS9 | K7EKS9_HUMAN | Cholesterol transporter ABCA5 | ABCA5 | 63 | Annotation score: | ||
K7EQ50 | K7EQ50_HUMAN | Cholesterol transporter ABCA5 | ABCA5 | 38 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 1215 | Y → H in BAB71208 (PubMed:14702039).Curated | 1 | |
Sequence conflicti | 1357 | V → I in CAB93535 (PubMed:12504089).Curated | 1 | |
Sequence conflicti | 1366 | T → S in CAB93535 (PubMed:12504089).Curated | 1 | |
Sequence conflicti | 1371 | D → G in BAB71208 (PubMed:14702039).Curated | 1 | |
Sequence conflicti | 1419 | A → G in BAB71208 (PubMed:14702039).Curated | 1 | |
Sequence conflicti | 1523 | K → R in BAB71208 (PubMed:14702039).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_027571 | 93 | Q → K. Corresponds to variant dbSNP:rs12383Ensembl. | 1 | |
Natural variantiVAR_048128 | 178 | A → T1 PublicationCorresponds to variant dbSNP:rs11544715Ensembl. | 1 | |
Natural variantiVAR_027572 | 484 | Q → R1 PublicationCorresponds to variant dbSNP:rs17686569Ensembl. | 1 | |
Natural variantiVAR_027573 | 753 | M → V. Corresponds to variant dbSNP:rs9898003Ensembl. | 1 | |
Natural variantiVAR_027574 | 832 | A → S3 PublicationsCorresponds to variant dbSNP:rs536009Ensembl. | 1 | |
Natural variantiVAR_027575 | 960 | M → V1 PublicationCorresponds to variant dbSNP:rs557491Ensembl. | 1 | |
Natural variantiVAR_048129 | 1260 | D → G. Corresponds to variant dbSNP:rs11544716Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_020690 | 1 – 777 | Missing in isoform 3. 1 PublicationAdd BLAST | 777 | |
Alternative sequenceiVSP_020691 | 922 – 925 | DSDI → GESV in isoform 2. 1 Publication | 4 | |
Alternative sequenceiVSP_020692 | 926 – 1642 | Missing in isoform 2. 1 PublicationAdd BLAST | 717 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY028897 mRNA Translation: AAK30022.1 AJ275973 mRNA Translation: CAB93535.3 AJ512612 mRNA Translation: CAD54757.1 AK056533 mRNA Translation: BAB71208.1 AK058170 mRNA Translation: BAB71700.1 Different initiation. AB067475 mRNA Translation: BAB67781.1 |
CCDSi | CCDS11685.1 [Q8WWZ7-1] |
RefSeqi | NP_061142.2, NM_018672.4 [Q8WWZ7-1] NP_758424.1, NM_172232.3 [Q8WWZ7-1] |
Genome annotation databases
Ensembli | ENST00000392676; ENSP00000376443; ENSG00000154265 ENST00000588877; ENSP00000467882; ENSG00000154265 |
GeneIDi | 23461 |
KEGGi | hsa:23461 |
MANE-Selecti | ENST00000392676.8; ENSP00000376443.2; NM_172232.4; NP_758424.1 |
UCSCi | uc002jif.3, human [Q8WWZ7-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Web resourcesi
ABCMdb Database for mutations in ABC proteins |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY028897 mRNA Translation: AAK30022.1 AJ275973 mRNA Translation: CAB93535.3 AJ512612 mRNA Translation: CAD54757.1 AK056533 mRNA Translation: BAB71208.1 AK058170 mRNA Translation: BAB71700.1 Different initiation. AB067475 mRNA Translation: BAB67781.1 |
CCDSi | CCDS11685.1 [Q8WWZ7-1] |
RefSeqi | NP_061142.2, NM_018672.4 [Q8WWZ7-1] NP_758424.1, NM_172232.3 [Q8WWZ7-1] |
3D structure databases
SMRi | Q8WWZ7 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 117024, 4 interactors |
IntActi | Q8WWZ7, 3 interactors |
STRINGi | 9606.ENSP00000376443 |
Chemistry databases
DrugBanki | DB00864, Tacrolimus |
Protein family/group databases
TCDBi | 3.A.1.211.9, the atp-binding cassette (abc) superfamily |
PTM databases
GlyGeni | Q8WWZ7, 3 sites |
iPTMneti | Q8WWZ7 |
PhosphoSitePlusi | Q8WWZ7 |
Genetic variation databases
BioMutai | ABCA5 |
DMDMi | 115503762 |
Proteomic databases
EPDi | Q8WWZ7 |
jPOSTi | Q8WWZ7 |
MassIVEi | Q8WWZ7 |
MaxQBi | Q8WWZ7 |
PaxDbi | Q8WWZ7 |
PeptideAtlasi | Q8WWZ7 |
PRIDEi | Q8WWZ7 |
ProteomicsDBi | 74970 [Q8WWZ7-1] 74971 [Q8WWZ7-2] 74972 [Q8WWZ7-3] |
Protocols and materials databases
Antibodypediai | 19335, 180 antibodies from 28 providers |
DNASUi | 23461 |
Genome annotation databases
Ensembli | ENST00000392676; ENSP00000376443; ENSG00000154265 ENST00000588877; ENSP00000467882; ENSG00000154265 |
GeneIDi | 23461 |
KEGGi | hsa:23461 |
MANE-Selecti | ENST00000392676.8; ENSP00000376443.2; NM_172232.4; NP_758424.1 |
UCSCi | uc002jif.3, human [Q8WWZ7-1] |
Organism-specific databases
CTDi | 23461 |
DisGeNETi | 23461 |
GeneCardsi | ABCA5 |
HGNCi | HGNC:35, ABCA5 |
HPAi | ENSG00000154265, Low tissue specificity |
MalaCardsi | ABCA5 |
MIMi | 612503, gene |
neXtProti | NX_Q8WWZ7 |
OpenTargetsi | ENSG00000154265 |
Orphaneti | 2026, Gingival fibromatosis-hypertrichosis syndrome |
PharmGKBi | PA24380 |
VEuPathDBi | HostDB:ENSG00000154265 |
HUGEi | Search... |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG0059, Eukaryota |
GeneTreei | ENSGT00940000158172 |
InParanoidi | Q8WWZ7 |
OMAi | LQLACMF |
OrthoDBi | 131191at2759 |
PhylomeDBi | Q8WWZ7 |
TreeFami | TF105192 |
Enzyme and pathway databases
PathwayCommonsi | Q8WWZ7 |
Reactomei | R-HSA-1369062, ABC transporters in lipid homeostasis |
SignaLinki | Q8WWZ7 |
Miscellaneous databases
BioGRID-ORCSi | 23461, 8 hits in 1041 CRISPR screens |
ChiTaRSi | ABCA5, human |
GenomeRNAii | 23461 |
Pharosi | Q8WWZ7, Tbio |
PROi | PR:Q8WWZ7 |
RNActi | Q8WWZ7, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000154265, Expressed in intestine and 239 other tissues |
ExpressionAtlasi | Q8WWZ7, baseline and differential |
Genevisiblei | Q8WWZ7, HS |
Family and domain databases
Gene3Di | 3.40.50.300, 2 hits |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003439, ABC_transporter-like_ATP-bd IPR017871, ABC_transporter-like_CS IPR026082, ABCA IPR030367, ABCA5 IPR027417, P-loop_NTPase |
PANTHERi | PTHR19229, PTHR19229, 1 hit PTHR19229:SF100, PTHR19229:SF100, 1 hit |
Pfami | View protein in Pfam PF00005, ABC_tran, 2 hits |
SMARTi | View protein in SMART SM00382, AAA, 2 hits |
SUPFAMi | SSF52540, SSF52540, 2 hits |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | ABCA5_HUMAN | |
Accessioni | Q8WWZ7Primary (citable) accession number: Q8WWZ7 Secondary accession number(s): Q8IVJ2 Q9NY14 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 3, 2006 |
Last sequence update: | October 3, 2006 | |
Last modified: | February 23, 2022 | |
This is version 145 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 17
Human chromosome 17: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families