Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 109 (07 Oct 2020)
Sequence version 1 (01 Mar 2002)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Serine-rich single-pass membrane protein 1

Gene

SSMEM1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q8WWF3

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Serine-rich single-pass membrane protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SSMEM1
Synonyms:C7orf45
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000165120.3

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29580, SSMEM1

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8WWF3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei35 – 55HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000165120

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162380490

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8WWF3, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SSMEM1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74730975

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002713541 – 244Serine-rich single-pass membrane protein 1Add BLAST244

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8WWF3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8WWF3

PeptideAtlas

More...
PeptideAtlasi
Q8WWF3

PRoteomics IDEntifications database

More...
PRIDEi
Q8WWF3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
74880

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8WWF3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8WWF3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000165120, Expressed in testis and 35 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8WWF3, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8WWF3, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000165120, Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q8WWF3
With#Exp.IntAct
ALG3 [Q92685]3EBI-17280858,EBI-2848814
APOA2 [P02652]3EBI-17280858,EBI-1171525
AQP1 [P29972]3EBI-17280858,EBI-745213
AQP10 [Q96PS8]3EBI-17280858,EBI-12820279
AQP3 [Q92482]3EBI-17280858,EBI-2808854
ATP6V0C [P27449]3EBI-17280858,EBI-721179
BET1 [O15155]3EBI-17280858,EBI-749204
BLCAP [P62952]3EBI-17280858,EBI-3895726
C11orf24 [Q96F05]3EBI-17280858,EBI-2836238
C1QL4 [Q86Z23]3EBI-17280858,EBI-12062109
C4orf3 - isoform 2 [Q8WVX3-2]3EBI-17280858,EBI-12003442
C5 [P01031]3EBI-17280858,EBI-8558308
CCL4L2 [Q8NHW4]3EBI-17280858,EBI-10271156
CDS2 [O95674]3EBI-17280858,EBI-3913685
CLRN2 [A0PK11]3EBI-17280858,EBI-12813623
CMTM7 [Q96FZ5]3EBI-17280858,EBI-2807956
CSGALNACT2 [Q8N6G5]3EBI-17280858,EBI-10267100
CXCL9 [Q07325]3EBI-17280858,EBI-3911467
CYB561 [P49447]3EBI-17280858,EBI-8646596
CYBC1 [Q9BQA9]3EBI-17280858,EBI-2680384
DEFB103B [P81534]3EBI-17280858,EBI-12074168
DEFB121 [Q5J5C9]3EBI-17280858,EBI-10244198
EFNA5 [P52803]3EBI-17280858,EBI-1753674
EHHADH [Q08426]3EBI-17280858,EBI-2339219
EMD [P50402]3EBI-17280858,EBI-489887
ERG28 [Q9UKR5]3EBI-17280858,EBI-711490
ERMP1 [Q7Z2K6]3EBI-17280858,EBI-10976398
FAM3C [Q92520]3EBI-17280858,EBI-2876774
FATE1 [Q969F0]3EBI-17280858,EBI-743099
FDPS [P14324]3EBI-17280858,EBI-948245
FPR2 [P25090]3EBI-17280858,EBI-17291771
GET3 [O43681]3EBI-17280858,EBI-2515857
GJB2 [P29033]3EBI-17280858,EBI-3905204
GPHB5 [Q86YW7]3EBI-17280858,EBI-11659720
GPR151 [Q8TDV0]3EBI-17280858,EBI-11955647
HMOX2 [P30519]3EBI-17280858,EBI-712096
LAT - isoform 2 [O43561-2]3EBI-17280858,EBI-8070286
LEPROTL1 [O95214]3EBI-17280858,EBI-750776
LNPEP - isoform 2 [Q9UIQ6-2]3EBI-17280858,EBI-12133176
MARCHF2 [Q9P0N8]3EBI-17280858,EBI-10317612
MCRS1 [Q96EZ8]3EBI-17280858,EBI-348259
MFSD12 - isoform 2 [Q6NUT3-2]3EBI-17280858,EBI-17295698
MFSD5 [Q6N075]3EBI-17280858,EBI-3920969
MFSD6 [Q6ZSS7]3EBI-17280858,EBI-2858252
MIP [P30301]3EBI-17280858,EBI-8449636
MMD2 - isoform 2 [Q8IY49-2]3EBI-17280858,EBI-13349813
MS4A13 [Q5J8X5]3EBI-17280858,EBI-12070086
NIPAL4 [Q0D2K0]3EBI-17280858,EBI-9550165
NRM [Q8IXM6]3EBI-17280858,EBI-10262547
PGAP2 - isoform 5 [Q9UHJ9-5]3EBI-17280858,EBI-12092917
PLPP1 [O14494]3EBI-17280858,EBI-2865290
PLPP4 [Q5VZY2]3EBI-17280858,EBI-10485931
PLPP6 [Q8IY26]3EBI-17280858,EBI-11721828
PLPPR2 [Q96GM1]3EBI-17280858,EBI-12955265
PPGB [Q59EV6]3EBI-17280858,EBI-14210385
RHD - isoform 2 [Q02161-2]3EBI-17280858,EBI-17249212
RTP2 [Q5QGT7]3EBI-17280858,EBI-10244780
RUSF1 [Q96GQ5]3EBI-17280858,EBI-8636004
S1PR5 [Q9H228]3EBI-17280858,EBI-2564169
SERP1 [Q9Y6X1]3EBI-17280858,EBI-10329948
SLC30A2 [Q9BRI3]3EBI-17280858,EBI-8644112
SLC30A8 [Q8IWU4]3EBI-17280858,EBI-10262251
SLC35A1 [P78382]3EBI-17280858,EBI-12870360
SLC35A4 [Q96G79]3EBI-17280858,EBI-12363689
SLC35C2 - isoform 3 [Q9NQQ7-3]3EBI-17280858,EBI-17295964
SLC35E3 [Q7Z769]3EBI-17280858,EBI-13389236
SLC38A1 [Q9H2H9]3EBI-17280858,EBI-9978441
SLC38A7 [Q9NVC3]3EBI-17280858,EBI-10314552
SLC39A2 [Q9NP94]3EBI-17280858,EBI-12898013
SLC39A9 [Q9NUM3]3EBI-17280858,EBI-2823239
SLC41A1 [Q8IVJ1]3EBI-17280858,EBI-12266234
SLC41A2 [Q96JW4]3EBI-17280858,EBI-10290130
STX8 [Q9UNK0]3EBI-17280858,EBI-727240
TAP1 [Q03518]3EBI-17280858,EBI-747259
TAS2R10 [Q9NYW0]3EBI-17280858,EBI-12963900
TLCD1 [Q96CP7]3EBI-17280858,EBI-11337932
TM6SF2 [Q9BZW4]3EBI-17280858,EBI-13082040
TMEM128 - isoform 2 [Q5BJH2-2]3EBI-17280858,EBI-10694905
TMEM144 [Q7Z5S9]3EBI-17280858,EBI-12876358
TMEM14A [Q9Y6G1]3EBI-17280858,EBI-2800360
TMEM14C [Q9P0S9]3EBI-17280858,EBI-2339195
TMEM203 [Q969S6]3EBI-17280858,EBI-12274070
TMEM218 [A2RU14]3EBI-17280858,EBI-10173151
TMEM222 [Q9H0R3]3EBI-17280858,EBI-347385
TMEM239 - isoform 2 [Q8WW34-2]3EBI-17280858,EBI-11528917
TMEM243 [Q9BU79]3EBI-17280858,EBI-12887458
TMEM45A [Q9NWC5]3EBI-17280858,EBI-10823938
TMEM60 [Q9H2L4]3EBI-17280858,EBI-2852148
TMEM86A [Q8N2M4]3EBI-17280858,EBI-12015604
TMEM86B [Q8N661]3EBI-17280858,EBI-2548832
TMEM97 [Q5BJF2]3EBI-17280858,EBI-12111910
TMPPE [Q6ZT21]3EBI-17280858,EBI-11724433
TNF [P01375]3EBI-17280858,EBI-359977
TUSC5 [A5PKU2]3EBI-17280858,EBI-11988865
UNC93B1 [Q9H1C4]3EBI-17280858,EBI-4401271
UPK1B [O75841]3EBI-17280858,EBI-12237619
VAMP4 [O75379]3EBI-17280858,EBI-744953
YIPF6 [Q96EC8]3EBI-17280858,EBI-751210
ZFPL1 [O95159]3EBI-17280858,EBI-718439

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
126451, 106 interactors

Protein interaction database and analysis system

More...
IntActi
Q8WWF3, 110 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000297819

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8WWF3, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502S512, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000015907

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_099475_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8WWF3

Identification of Orthologs from Complete Genome Data

More...
OMAi
PEINTKF

Database of Orthologous Groups

More...
OrthoDBi
1140894at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8WWF3

TreeFam database of animal gene trees

More...
TreeFami
TF337221

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027955, DUF4636

The PANTHER Classification System

More...
PANTHERi
PTHR31822, PTHR31822, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15468, DUF4636, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q8WWF3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGDLFSLFWE VDPPPIPVNC AIPNQDYECW KDDSCGTIGS FLLWYFVIVF
60 70 80 90 100
VLMFFSRASV WMSEDKKDEG SGTSTSVRKA SKETSCKRQS KDSAWDPSQT
110 120 130 140 150
MKKPKQNQLT PVTNSEVALV NAYPEQRRAR RQSQFNEVNQ NQHDSDTTEY
160 170 180 190 200
GSEESNSEAS SWKESESEHH PSPDSIKRRK MAQRQRNLGS YQMSERHCLH
210 220 230 240
CKALRTNEWL AHHSRQKPSV TPPMKRDSQE ESSISDINKK FSKF
Length:244
Mass (Da):28,167
Last modified:March 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i14EB74E45FE0303D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A3B3ISA2A0A3B3ISA2_HUMAN
Serine-rich single-pass membrane pr...
SSMEM1
183Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02987388R → W. Corresponds to variant dbSNP:rs4728190Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK097635 mRNA Translation: BAC05126.1
BC017587 mRNA Translation: AAH17587.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5816.1

NCBI Reference Sequences

More...
RefSeqi
NP_660311.1, NM_145268.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000297819; ENSP00000297819; ENSG00000165120

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
136263

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:136263

UCSC genome browser

More...
UCSCi
uc003vpp.4, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK097635 mRNA Translation: BAC05126.1
BC017587 mRNA Translation: AAH17587.1
CCDSiCCDS5816.1
RefSeqiNP_660311.1, NM_145268.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi126451, 106 interactors
IntActiQ8WWF3, 110 interactors
STRINGi9606.ENSP00000297819

PTM databases

iPTMnetiQ8WWF3
PhosphoSitePlusiQ8WWF3

Polymorphism and mutation databases

BioMutaiSSMEM1
DMDMi74730975

Proteomic databases

MassIVEiQ8WWF3
PaxDbiQ8WWF3
PeptideAtlasiQ8WWF3
PRIDEiQ8WWF3
ProteomicsDBi74880

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
17943, 55 antibodies

The DNASU plasmid repository

More...
DNASUi
136263

Genome annotation databases

EnsembliENST00000297819; ENSP00000297819; ENSG00000165120
GeneIDi136263
KEGGihsa:136263
UCSCiuc003vpp.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
136263
EuPathDBiHostDB:ENSG00000165120.3

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SSMEM1
HGNCiHGNC:29580, SSMEM1
HPAiENSG00000165120, Tissue enriched (testis)
neXtProtiNX_Q8WWF3
OpenTargetsiENSG00000165120
PharmGKBiPA162380490

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502S512, Eukaryota
GeneTreeiENSGT00390000015907
HOGENOMiCLU_099475_0_0_1
InParanoidiQ8WWF3
OMAiPEINTKF
OrthoDBi1140894at2759
PhylomeDBiQ8WWF3
TreeFamiTF337221

Enzyme and pathway databases

PathwayCommonsiQ8WWF3

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
136263, 3 hits in 867 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
136263
PharosiQ8WWF3, Tdark

Protein Ontology

More...
PROi
PR:Q8WWF3
RNActiQ8WWF3, protein

Gene expression databases

BgeeiENSG00000165120, Expressed in testis and 35 other tissues
ExpressionAtlasiQ8WWF3, baseline and differential
GenevisibleiQ8WWF3, HS

Family and domain databases

InterProiView protein in InterPro
IPR027955, DUF4636
PANTHERiPTHR31822, PTHR31822, 1 hit
PfamiView protein in Pfam
PF15468, DUF4636, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSSMM1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8WWF3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: March 1, 2002
Last modified: October 7, 2020
This is version 109 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again