UniProtKB - Q8WW38 (FOG2_HUMAN)
Zinc finger protein ZFPM2
ZFPM2
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 244 – 277 | CCHC FOG-type 1PROSITE-ProRule annotationAdd BLAST | 34 | |
Zinc fingeri | 296 – 320 | C2H2-type 1PROSITE-ProRule annotationAdd BLAST | 25 | |
Zinc fingeri | 335 – 357 | C2H2-type 2PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 363 – 385 | C2H2-type 3PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 542 – 575 | CCHC FOG-type 2PROSITE-ProRule annotationAdd BLAST | 34 | |
Zinc fingeri | 681 – 714 | CCHC FOG-type 3PROSITE-ProRule annotationAdd BLAST | 34 | |
Zinc fingeri | 848 – 881 | CCHC FOG-type 4PROSITE-ProRule annotationAdd BLAST | 34 | |
Zinc fingeri | 1113 – 1146 | CCHC FOG-type 5PROSITE-ProRule annotationAdd BLAST | 34 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- RNA polymerase II transcription factor binding Source: GO_Central
- transcription coactivator activity Source: BHF-UCL
- transcription corepressor activity Source: BHF-UCL
- transcription factor binding Source: BHF-UCL
- zinc ion binding Source: BHF-UCL
GO - Biological processi
- blood coagulation Source: Reactome
- cell differentiation Source: GO_Central
- embryonic organ development Source: Ensembl
- gonadal mesoderm development Source: UniProtKB-KW
- heart development Source: GO_Central
- in utero embryonic development Source: Ensembl
- lung development Source: Ensembl
- negative regulation of cell death Source: Ensembl
- negative regulation of fat cell differentiation Source: UniProtKB
- negative regulation of female gonad development Source: Ensembl
- negative regulation of transcription, DNA-templated Source: UniProtKB
- negative regulation of transcription by RNA polymerase II Source: BHF-UCL
- outflow tract septum morphogenesis Source: BHF-UCL
- positive regulation of cardiac muscle cell proliferation Source: BHF-UCL
- positive regulation of male gonad development Source: Ensembl
- positive regulation of transcription by RNA polymerase II Source: BHF-UCL
- right ventricular cardiac muscle tissue morphogenesis Source: BHF-UCL
- vasculogenesis Source: Ensembl
- ventricular septum morphogenesis Source: BHF-UCL
Keywordsi
Molecular function | Activator, DNA-binding, Repressor |
Biological process | Differentiation, Gonadal differentiation, Transcription, Transcription regulation |
Ligand | Metal-binding, Zinc |
Enzyme and pathway databases
PathwayCommonsi | Q8WW38 |
Reactomei | R-HSA-983231, Factors involved in megakaryocyte development and platelet production |
SIGNORi | Q8WW38 |
Names & Taxonomyi
Protein namesi | Recommended name: Zinc finger protein ZFPM2Alternative name(s): Friend of GATA protein 2 Short name: FOG-2 Short name: Friend of GATA 2 Short name: hFOG-2 Zinc finger protein 89B Zinc finger protein multitype 2 |
Gene namesi | Name:ZFPM2 Synonyms:FOG2, ZNF89B |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:16700, ZFPM2 |
MIMi | 603693, gene |
neXtProti | NX_Q8WW38 |
VEuPathDBi | HostDB:ENSG00000169946.13 |
Subcellular locationi
Nucleus
- Nucleus 1 Publication
Nucleus
- nuclear chromatin Source: NTNU_SB
- nucleoplasm Source: HPA
- nucleus Source: GO_Central
Other locations
- cytoplasm Source: Ensembl
Keywords - Cellular componenti
NucleusPathology & Biotechi
Involvement in diseasei
Tetralogy of Fallot (TOF)2 Publications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_017942 | 30 | E → G in TOF and CTHM; does not affect its ability to interact with GATA4. 2 PublicationsCorresponds to variant dbSNP:rs121908601EnsemblClinVar. | 1 | |
Natural variantiVAR_072075 | 544 | M → I in SRXY9 and TOF; reduced its ability to interact with GATA4. 2 PublicationsCorresponds to variant dbSNP:rs187043152EnsemblClinVar. | 1 | |
Natural variantiVAR_017943 | 657 | S → G in TOF; slightly impairs its ability to interact with GATA4. 1 PublicationCorresponds to variant dbSNP:rs28374544EnsemblClinVar. | 1 |
Diaphragmatic hernia 3 (DIH3)1 Publication
46,XY sex reversal 9 (SRXY9)1 Publication
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_071104 | 260 | R → Q in SRXY9; results in reduced transactivation activity on the AMH promoter; does not affect its ability to interact with GATA4. 1 PublicationCorresponds to variant dbSNP:rs200834568EnsemblClinVar. | 1 | |
Natural variantiVAR_071105 | 402 | S → R in SRXY9; results in reduced transactivation activity on the AMH promoter; abolished its ability to interact with GATA4. 1 PublicationCorresponds to variant dbSNP:rs606231252EnsemblClinVar. | 1 | |
Natural variantiVAR_072075 | 544 | M → I in SRXY9 and TOF; reduced its ability to interact with GATA4. 2 PublicationsCorresponds to variant dbSNP:rs187043152EnsemblClinVar. | 1 |
Conotruncal heart malformations (CTHM)1 Publication
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_017942 | 30 | E → G in TOF and CTHM; does not affect its ability to interact with GATA4. 2 PublicationsCorresponds to variant dbSNP:rs121908601EnsemblClinVar. | 1 | |
Natural variantiVAR_072074 | 227 | I → V in CTHM. 1 PublicationCorresponds to variant dbSNP:rs202204708EnsemblClinVar. | 1 |
Keywords - Diseasei
Cardiomyopathy, Disease variantOrganism-specific databases
DisGeNETi | 23414 |
MalaCardsi | ZFPM2 |
MIMi | 187500, phenotype 217095, phenotype 610187, phenotype 616067, phenotype |
OpenTargetsi | ENSG00000169946 |
Orphaneti | 251510, 46,XY partial gonadal dysgenesis 2140, Congenital diaphragmatic hernia 3303, Tetralogy of Fallot |
PharmGKBi | PA134947303 |
Miscellaneous databases
Pharosi | Q8WW38, Tbio |
Genetic variation databases
BioMutai | ZFPM2 |
DMDMi | 126302543 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000221043 | 1 – 1151 | Zinc finger protein ZFPM2Add BLAST | 1151 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Cross-linki | 324 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)1 Publication | ||
Cross-linki | 444 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources | ||
Cross-linki | 471 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)1 Publication | ||
Modified residuei | 532 | PhosphoserineCombined sources | 1 | |
Modified residuei | 581 | PhosphoserineCombined sources | 1 | |
Modified residuei | 904 | PhosphoserineCombined sources | 1 | |
Cross-linki | 915 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)1 Publication | ||
Cross-linki | 955 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)1 Publication | ||
Modified residuei | 1014 | PhosphoserineCombined sources | 1 |
Post-translational modificationi
Keywords - PTMi
Isopeptide bond, Phosphoprotein, Ubl conjugationProteomic databases
jPOSTi | Q8WW38 |
MassIVEi | Q8WW38 |
MaxQBi | Q8WW38 |
PaxDbi | Q8WW38 |
PeptideAtlasi | Q8WW38 |
PRIDEi | Q8WW38 |
ProteomicsDBi | 74858 [Q8WW38-1] 74859 [Q8WW38-2] |
PTM databases
iPTMneti | Q8WW38 |
PhosphoSitePlusi | Q8WW38 |
Expressioni
Tissue specificityi
Gene expression databases
Bgeei | ENSG00000169946, Expressed in cerebellum and 203 other tissues |
ExpressionAtlasi | Q8WW38, baseline and differential |
Genevisiblei | Q8WW38, HS |
Organism-specific databases
HPAi | ENSG00000169946, Tissue enhanced (brain, ovary) |
Interactioni
Subunit structurei
Interacts with the N-terminal zinc-finger of GATA4, GATA5 and probably GATA6.
Interacts with retinoid nuclear receptor RXRA when ligand bound (By similarity).
Interacts with corepressor CTBP2; this interaction is however not essential for corepressor activity. Able to bind GATA1 in vitro.
Interacts with NR2F2 and NR2F6 (By similarity).
Interacts with ATOH8; mediates indirect interaction with GATA4 (By similarity).
By similarity2 PublicationsBinary interactionsi
Hide detailsQ8WW38
With | #Exp. | IntAct |
---|---|---|
DMWD [G5E9A7] | 3 | EBI-947213,EBI-10976677 |
GFAP [P14136] | 3 | EBI-947213,EBI-744302 |
LMNA [P02545] | 3 | EBI-947213,EBI-351935 |
PRPF3 [O43395] | 3 | EBI-947213,EBI-744322 |
SPRED1 [Q7Z699] | 3 | EBI-947213,EBI-5235340 |
GO - Molecular functioni
- RNA polymerase II transcription factor binding Source: GO_Central
- transcription factor binding Source: BHF-UCL
Protein-protein interaction databases
BioGRIDi | 116986, 19 interactors |
ELMi | Q8WW38 |
IntActi | Q8WW38, 8 interactors |
STRINGi | 9606.ENSP00000384179 |
Miscellaneous databases
RNActi | Q8WW38, protein |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 829 – 835 | Interaction with CTBP2Curated | 7 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 736 – 740 | Nuclear localization signalBy similarity | 5 |
Domaini
Sequence similaritiesi
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 244 – 277 | CCHC FOG-type 1PROSITE-ProRule annotationAdd BLAST | 34 | |
Zinc fingeri | 296 – 320 | C2H2-type 1PROSITE-ProRule annotationAdd BLAST | 25 | |
Zinc fingeri | 335 – 357 | C2H2-type 2PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 363 – 385 | C2H2-type 3PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 542 – 575 | CCHC FOG-type 2PROSITE-ProRule annotationAdd BLAST | 34 | |
Zinc fingeri | 681 – 714 | CCHC FOG-type 3PROSITE-ProRule annotationAdd BLAST | 34 | |
Zinc fingeri | 848 – 881 | CCHC FOG-type 4PROSITE-ProRule annotationAdd BLAST | 34 | |
Zinc fingeri | 1113 – 1146 | CCHC FOG-type 5PROSITE-ProRule annotationAdd BLAST | 34 |
Keywords - Domaini
Repeat, Zinc-fingerPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00530000063823 |
InParanoidi | Q8WW38 |
OMAi | WQGVEDS |
OrthoDBi | 1030296at2759 |
PhylomeDBi | Q8WW38 |
TreeFami | TF331342 |
Family and domain databases
InterProi | View protein in InterPro IPR039746, FOG IPR034731, ZF_CCHC_FOG IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
PANTHERi | PTHR12958, PTHR12958, 1 hit |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 8 hits |
SUPFAMi | SSF57667, SSF57667, 6 hits |
PROSITEi | View protein in PROSITE PS51810, ZF_CCHC_FOG, 5 hits PS00028, ZINC_FINGER_C2H2_1, 2 hits PS50157, ZINC_FINGER_C2H2_2, 2 hits |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MSRRKQSKPR QIKRPLEDAI EDEEEECPSE ETDIISKGDF PLEESFSTEF
60 70 80 90 100
GPENLSCEEV EYFCNKGDDE GIQETAESDG DTQSEKPGQP GVETDDWDGP
110 120 130 140 150
GELEVFQKDG ERKIQSRQQL PVGTTWGPFP GKMDLNNNSL KTKAQVPMVL
160 170 180 190 200
TAGPKWLLDV TWQGVEDNKN NCIVYSKGGQ LWCTTTKAIS EGEELIAFVV
210 220 230 240 250
DFDSRLQAAS QMTLTEGMYP ARLLDSIQLL PQQAAMASIL PTAIVNKDIF
260 270 280 290 300
PCKSCGIWYR SERNLQAHLM YYCSGRQREA APVSEENEDS AHQISSLCPF
310 320 330 340 350
PQCTKSFSNA RALEMHLNSH SGVKMEEFLP PGASLKCTVC SYTADSVINF
360 370 380 390 400
HQHLFSHLTQ AAFRCNHCHF GFQTQRELLQ HQELHVPSGK LPRESDMEHS
410 420 430 440 450
PSATEDSLQP ATDLLTRSEL PQSQKAMQTK DASSDTELDK CEKKTQLFLT
460 470 480 490 500
NQRPEIQPTT NKQSFSYTKI KSEPSSPRLA SSPVQPNIGP SFPVGPFLSQ
510 520 530 540 550
FSFPQDITMV PQASEILAKM SELVHRRLRH GSSSYPPVIY SPLMPKGATC
560 570 580 590 600
FECNITFNNL DNYLVHKKHY CSSRWQQMAK SPEFPSVSEK MPEALSPNTG
610 620 630 640 650
QTSINLLNPA AHSADPENPL LQTSCINSST VLDLIGPNGK GHDKDFSTQT
660 670 680 690 700
KKLSTSSNND DKINGKPVDV KNPSVPLVDG ESDPNKTTCE ACNITFSRHE
710 720 730 740 750
TYMVHKQYYC ATRHDPPLKR SASNKVPAMQ RTMRTRKRRK MYEMCLPEQE
760 770 780 790 800
QRPPLVQQRF LDVANLNNPC TSTQEPTEGL GECYHPRCDI FPGIVSKHLE
810 820 830 840 850
TSLTINKCVP VSKCDTTHSS VSCLEMDVPI DLSKKCLSQS ERTTTSPKRL
860 870 880 890 900
LDYHECTVCK ISFNKVENYL AHKQNFCPVT AHQRNDLGQL DGKVFPNPES
910 920 930 940 950
ERNSPDVSYE RSIIKCEKNG NLKQPSPNGN LFSSHLATLQ GLKVFSEAAQ
960 970 980 990 1000
LIATKEENRH LFLPQCLYPG AIKKAKGADQ LSPYYGIKPS DYISGSLVIH
1010 1020 1030 1040 1050
NTDIEQSRNA ENESPKGQAS SNGCAALKKD SLPLLPKNRG MVIVNGGLKQ
1060 1070 1080 1090 1100
DERPAANPQQ ENISQNPQHE DDHKSPSWIS ENPLAANENV SPGIPSAEEQ
1110 1120 1130 1140 1150
LSSIAKGVNG SSQAPTSGKY CRLCDIQFNN LSNFITHKKF YCSSHAAEHV
K
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketE7ET52 | E7ET52_HUMAN | Zinc finger protein ZFPM2 | ZFPM2 | 1,019 | Annotation score: | ||
E5RJX0 | E5RJX0_HUMAN | Zinc finger protein ZFPM2 | ZFPM2 | 26 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 198 | F → L in CAB97541 (Ref. 3) Curated | 1 | |
Sequence conflicti | 939 | L → P in AAD49558 (PubMed:10438528).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_017942 | 30 | E → G in TOF and CTHM; does not affect its ability to interact with GATA4. 2 PublicationsCorresponds to variant dbSNP:rs121908601EnsemblClinVar. | 1 | |
Natural variantiVAR_072074 | 227 | I → V in CTHM. 1 PublicationCorresponds to variant dbSNP:rs202204708EnsemblClinVar. | 1 | |
Natural variantiVAR_071104 | 260 | R → Q in SRXY9; results in reduced transactivation activity on the AMH promoter; does not affect its ability to interact with GATA4. 1 PublicationCorresponds to variant dbSNP:rs200834568EnsemblClinVar. | 1 | |
Natural variantiVAR_071105 | 402 | S → R in SRXY9; results in reduced transactivation activity on the AMH promoter; abolished its ability to interact with GATA4. 1 PublicationCorresponds to variant dbSNP:rs606231252EnsemblClinVar. | 1 | |
Natural variantiVAR_024178 | 403 | A → G1 PublicationCorresponds to variant dbSNP:rs11993776EnsemblClinVar. | 1 | |
Natural variantiVAR_072075 | 544 | M → I in SRXY9 and TOF; reduced its ability to interact with GATA4. 2 PublicationsCorresponds to variant dbSNP:rs187043152EnsemblClinVar. | 1 | |
Natural variantiVAR_017943 | 657 | S → G in TOF; slightly impairs its ability to interact with GATA4. 1 PublicationCorresponds to variant dbSNP:rs28374544EnsemblClinVar. | 1 | |
Natural variantiVAR_017944 | 782 | E → D1 PublicationCorresponds to variant dbSNP:rs2920048EnsemblClinVar. | 1 | |
Natural variantiVAR_030760 | 1055 | A → V. Corresponds to variant dbSNP:rs16873741EnsemblClinVar. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_009701 | 1 – 132 | Missing in isoform 2. 1 PublicationAdd BLAST | 132 | |
Alternative sequenceiVSP_009702 | 247 – 287 | KDIFP…VSEEN → SKCSVLCSPALEVMGIYGRK KCLLTRNQEQTFFLQKKKKK K in isoform 2. 1 PublicationAdd BLAST | 41 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF119334 mRNA Translation: AAD49558.1 BC020928 mRNA Translation: AAH20928.1 BC109222 mRNA Translation: AAI09223.1 AL389987 mRNA Translation: CAB97539.1 AL389989 mRNA Translation: CAB97541.1 |
CCDSi | CCDS47908.1 [Q8WW38-1] |
RefSeqi | NP_036214.2, NM_012082.3 [Q8WW38-1] |
Genome annotation databases
Ensembli | ENST00000407775; ENSP00000384179; ENSG00000169946 [Q8WW38-1] |
GeneIDi | 23414 |
KEGGi | hsa:23414 |
UCSCi | uc003ymd.4, human [Q8WW38-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF119334 mRNA Translation: AAD49558.1 BC020928 mRNA Translation: AAH20928.1 BC109222 mRNA Translation: AAI09223.1 AL389987 mRNA Translation: CAB97539.1 AL389989 mRNA Translation: CAB97541.1 |
CCDSi | CCDS47908.1 [Q8WW38-1] |
RefSeqi | NP_036214.2, NM_012082.3 [Q8WW38-1] |
3D structure databases
SMRi | Q8WW38 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 116986, 19 interactors |
ELMi | Q8WW38 |
IntActi | Q8WW38, 8 interactors |
STRINGi | 9606.ENSP00000384179 |
PTM databases
iPTMneti | Q8WW38 |
PhosphoSitePlusi | Q8WW38 |
Genetic variation databases
BioMutai | ZFPM2 |
DMDMi | 126302543 |
Proteomic databases
jPOSTi | Q8WW38 |
MassIVEi | Q8WW38 |
MaxQBi | Q8WW38 |
PaxDbi | Q8WW38 |
PeptideAtlasi | Q8WW38 |
PRIDEi | Q8WW38 |
ProteomicsDBi | 74858 [Q8WW38-1] 74859 [Q8WW38-2] |
Protocols and materials databases
Antibodypediai | 1311, 136 antibodies |
Genome annotation databases
Ensembli | ENST00000407775; ENSP00000384179; ENSG00000169946 [Q8WW38-1] |
GeneIDi | 23414 |
KEGGi | hsa:23414 |
UCSCi | uc003ymd.4, human [Q8WW38-1] |
Organism-specific databases
CTDi | 23414 |
DisGeNETi | 23414 |
GeneCardsi | ZFPM2 |
HGNCi | HGNC:16700, ZFPM2 |
HPAi | ENSG00000169946, Tissue enhanced (brain, ovary) |
MalaCardsi | ZFPM2 |
MIMi | 187500, phenotype 217095, phenotype 603693, gene 610187, phenotype 616067, phenotype |
neXtProti | NX_Q8WW38 |
OpenTargetsi | ENSG00000169946 |
Orphaneti | 251510, 46,XY partial gonadal dysgenesis 2140, Congenital diaphragmatic hernia 3303, Tetralogy of Fallot |
PharmGKBi | PA134947303 |
VEuPathDBi | HostDB:ENSG00000169946.13 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00530000063823 |
InParanoidi | Q8WW38 |
OMAi | WQGVEDS |
OrthoDBi | 1030296at2759 |
PhylomeDBi | Q8WW38 |
TreeFami | TF331342 |
Enzyme and pathway databases
PathwayCommonsi | Q8WW38 |
Reactomei | R-HSA-983231, Factors involved in megakaryocyte development and platelet production |
SIGNORi | Q8WW38 |
Miscellaneous databases
BioGRID-ORCSi | 23414, 7 hits in 896 CRISPR screens |
ChiTaRSi | ZFPM2, human |
GeneWikii | ZFPM2 |
GenomeRNAii | 23414 |
Pharosi | Q8WW38, Tbio |
PROi | PR:Q8WW38 |
RNActi | Q8WW38, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000169946, Expressed in cerebellum and 203 other tissues |
ExpressionAtlasi | Q8WW38, baseline and differential |
Genevisiblei | Q8WW38, HS |
Family and domain databases
InterProi | View protein in InterPro IPR039746, FOG IPR034731, ZF_CCHC_FOG IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
PANTHERi | PTHR12958, PTHR12958, 1 hit |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 8 hits |
SUPFAMi | SSF57667, SSF57667, 6 hits |
PROSITEi | View protein in PROSITE PS51810, ZF_CCHC_FOG, 5 hits PS00028, ZINC_FINGER_C2H2_1, 2 hits PS50157, ZINC_FINGER_C2H2_2, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | FOG2_HUMAN | |
Accessioni | Q8WW38Primary (citable) accession number: Q8WW38 Secondary accession number(s): Q32MA6 Q9UNI5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 15, 2004 |
Last sequence update: | February 20, 2007 | |
Last modified: | February 10, 2021 | |
This is version 157 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families - Human chromosome 8
Human chromosome 8: entries, gene names and cross-references to MIM