Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Zinc finger CCHC domain-containing protein 13

Gene

ZCCHC13

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri4 – 21CCHC-type 1; degeneratePROSITE-ProRule annotationAdd BLAST18
Zinc fingeri45 – 62CCHC-type 2; degeneratePROSITE-ProRule annotationAdd BLAST18
Zinc fingeri65 – 82CCHC-type 3PROSITE-ProRule annotationAdd BLAST18
Zinc fingeri89 – 106CCHC-type 4PROSITE-ProRule annotationAdd BLAST18
Zinc fingeri110 – 127CCHC-type 5PROSITE-ProRule annotationAdd BLAST18
Zinc fingeri128 – 145CCHC-type 6PROSITE-ProRule annotationAdd BLAST18

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger CCHC domain-containing protein 13
Gene namesi
Name:ZCCHC13
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000187969.5
HGNCiHGNC:31749 ZCCHC13
neXtProtiNX_Q8WW36

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000187969
PharmGKBiPA134926925

Polymorphism and mutation databases

BioMutaiZCCHC13
DMDMi71152962

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001509741 – 166Zinc finger CCHC domain-containing protein 13Add BLAST166

Proteomic databases

PaxDbiQ8WW36
PeptideAtlasiQ8WW36
PRIDEiQ8WW36
ProteomicsDBi74857

PTM databases

iPTMnetiQ8WW36
PhosphoSitePlusiQ8WW36

Expressioni

Gene expression databases

BgeeiENSG00000187969 Expressed in 13 organ(s), highest expression level in testis
CleanExiHS_ZCCHC13
GenevisibleiQ8WW36 HS

Organism-specific databases

HPAiHPA003382

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
SIAH1Q8IUQ43EBI-954111,EBI-747107

Protein-protein interaction databases

BioGridi133309, 2 interactors
IntActiQ8WW36, 6 interactors
STRINGi9606.ENSP00000345633

Structurei

3D structure databases

ProteinModelPortaliQ8WW36
SMRiQ8WW36
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri4 – 21CCHC-type 1; degeneratePROSITE-ProRule annotationAdd BLAST18
Zinc fingeri45 – 62CCHC-type 2; degeneratePROSITE-ProRule annotationAdd BLAST18
Zinc fingeri65 – 82CCHC-type 3PROSITE-ProRule annotationAdd BLAST18
Zinc fingeri89 – 106CCHC-type 4PROSITE-ProRule annotationAdd BLAST18
Zinc fingeri110 – 127CCHC-type 5PROSITE-ProRule annotationAdd BLAST18
Zinc fingeri128 – 145CCHC-type 6PROSITE-ProRule annotationAdd BLAST18

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG4400 Eukaryota
COG5082 LUCA
GeneTreeiENSGT00510000047065
HOGENOMiHOG000186262
HOVERGENiHBG000397
InParanoidiQ8WW36
OMAiGEDSICY
OrthoDBiEOG091G0LZK
PhylomeDBiQ8WW36
TreeFamiTF316974

Family and domain databases

InterProiView protein in InterPro
IPR001878 Znf_CCHC
IPR036875 Znf_CCHC_sf
PfamiView protein in Pfam
PF00098 zf-CCHC, 4 hits
SMARTiView protein in SMART
SM00343 ZnF_C2HC, 6 hits
SUPFAMiSSF57756 SSF57756, 3 hits
PROSITEiView protein in PROSITE
PS50158 ZF_CCHC, 4 hits

Sequencei

Sequence statusi: Complete.

Q8WW36-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSKDFFACG HSGHWARGCP RGGAGGRRGG GHGRGSQCGS TTLSYTCYCC
60 70 80 90 100
GESGRNAKNC VLLGNICYNC GRSGHIAKDC KDPKRERRQH CYTCGRLGHL
110 120 130 140 150
ARDCDRQKEQ KCYSCGKLGH IQKDCAQVKC YRCGEIGHVA INCSKARPGQ
160
LLPLRQIPTS SQGMSQ
Length:166
Mass (Da):18,005
Last modified:March 1, 2002 - v1
Checksum:i40CC28B9FF3F64C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC021176 mRNA Translation: AAH21176.1
CCDSiCCDS14425.1
RefSeqiNP_976048.1, NM_203303.2
UniGeneiHs.157231

Genome annotation databases

EnsembliENST00000339534; ENSP00000345633; ENSG00000187969
GeneIDi389874
KEGGihsa:389874
UCSCiuc004ebs.5 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC021176 mRNA Translation: AAH21176.1
CCDSiCCDS14425.1
RefSeqiNP_976048.1, NM_203303.2
UniGeneiHs.157231

3D structure databases

ProteinModelPortaliQ8WW36
SMRiQ8WW36
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi133309, 2 interactors
IntActiQ8WW36, 6 interactors
STRINGi9606.ENSP00000345633

PTM databases

iPTMnetiQ8WW36
PhosphoSitePlusiQ8WW36

Polymorphism and mutation databases

BioMutaiZCCHC13
DMDMi71152962

Proteomic databases

PaxDbiQ8WW36
PeptideAtlasiQ8WW36
PRIDEiQ8WW36
ProteomicsDBi74857

Protocols and materials databases

DNASUi389874
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000339534; ENSP00000345633; ENSG00000187969
GeneIDi389874
KEGGihsa:389874
UCSCiuc004ebs.5 human

Organism-specific databases

CTDi389874
EuPathDBiHostDB:ENSG00000187969.5
GeneCardsiZCCHC13
HGNCiHGNC:31749 ZCCHC13
HPAiHPA003382
neXtProtiNX_Q8WW36
OpenTargetsiENSG00000187969
PharmGKBiPA134926925
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4400 Eukaryota
COG5082 LUCA
GeneTreeiENSGT00510000047065
HOGENOMiHOG000186262
HOVERGENiHBG000397
InParanoidiQ8WW36
OMAiGEDSICY
OrthoDBiEOG091G0LZK
PhylomeDBiQ8WW36
TreeFamiTF316974

Miscellaneous databases

GenomeRNAii389874
PROiPR:Q8WW36

Gene expression databases

BgeeiENSG00000187969 Expressed in 13 organ(s), highest expression level in testis
CleanExiHS_ZCCHC13
GenevisibleiQ8WW36 HS

Family and domain databases

InterProiView protein in InterPro
IPR001878 Znf_CCHC
IPR036875 Znf_CCHC_sf
PfamiView protein in Pfam
PF00098 zf-CCHC, 4 hits
SMARTiView protein in SMART
SM00343 ZnF_C2HC, 6 hits
SUPFAMiSSF57756 SSF57756, 3 hits
PROSITEiView protein in PROSITE
PS50158 ZF_CCHC, 4 hits
ProtoNetiSearch...

Entry informationi

Entry nameiZCH13_HUMAN
AccessioniPrimary (citable) accession number: Q8WW36
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: March 1, 2002
Last modified: November 7, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again