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Entry version 115 (12 Aug 2020)
Sequence version 3 (19 Feb 2014)
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Protein

Transmembrane protein 239

Gene

TMEM239

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q8WW34

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transmembrane protein 239
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TMEM239
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000198326.9

Human Gene Nomenclature Database

More...
HGNCi
HGNC:40044, TMEM239

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8WW34

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei105 – 125HelicalSequence analysisAdd BLAST21
Transmembranei145 – 171HelicalSequence analysisAdd BLAST27

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
100288797

Open Targets

More...
OpenTargetsi
ENSG00000198326

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8WW34, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TMEM239

Domain mapping of disease mutations (DMDM)

More...
DMDMi
353558900

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004136941 – 195Transmembrane protein 239Add BLAST195

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8WW34

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8WW34

PeptideAtlas

More...
PeptideAtlasi
Q8WW34

PRoteomics IDEntifications database

More...
PRIDEi
Q8WW34

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
68307
74855 [Q8WW34-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8WW34

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8WW34

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000198326, Expressed in left testis and 50 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8WW34, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000198326, Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q8WW34
With#Exp.IntAct
ATF7 [P17544]3EBI-9675724,EBI-765623
C12orf10 [Q86UA3]3EBI-9675724,EBI-10258793
COQ8A [Q8NI60]5EBI-9675724,EBI-745535
FGD2 [Q7Z6J4]3EBI-9675724,EBI-1057190
LENG1 [Q96BZ8]3EBI-9675724,EBI-726510
POLI [Q9UNA4]3EBI-9675724,EBI-741774
SDCBP [O00560]3EBI-9675724,EBI-727004
SENP2 [Q9HC62]3EBI-9675724,EBI-714881
USP5 [P45974]3EBI-9675724,EBI-741277
WDYHV1 [Q96HA8]3EBI-9675724,EBI-741158
Isoform 2 [Q8WW34-2]
With#Exp.IntAct
AQP6 [Q13520]3EBI-11528917,EBI-13059134
CD79A [P11912]3EBI-11528917,EBI-7797864
CLDN20 [P56880]3EBI-11528917,EBI-23801559
CLRN1 [P58418]3EBI-11528917,EBI-17274839
COQ8A [Q8NI60]3EBI-11528917,EBI-745535
CREB3L1 [Q96BA8]3EBI-11528917,EBI-6942903
CREB3L3 [Q68CJ9]3EBI-11528917,EBI-852194
DARS2 [Q6PI48]3EBI-11528917,EBI-3917045
DCUN1D1 [Q96GG9]3EBI-11528917,EBI-740086
EBP [Q15125]3EBI-11528917,EBI-3915253
EMP1 [P54849]3EBI-11528917,EBI-4319440
FAM174A [Q8TBP5]3EBI-11528917,EBI-18636064
FBXL19 - isoform 2 [Q6PCT2-2]3EBI-11528917,EBI-11959077
FFAR2 [O15552]3EBI-11528917,EBI-2833872
FKBP7 [Q9Y680]3EBI-11528917,EBI-3918971
FTHL17 [Q9BXU8]3EBI-11528917,EBI-12156897
FXYD6 [Q9H0Q3]3EBI-11528917,EBI-713304
GJA8 [P48165]3EBI-11528917,EBI-17458373
GPR101 [Q96P66]3EBI-11528917,EBI-17935713
GPR151 [Q8TDV0]3EBI-11528917,EBI-11955647
GPR42 [O15529]3EBI-11528917,EBI-18076404
LNX1 [Q8TBB1]3EBI-11528917,EBI-739832
MFSD14B [Q5SR56]3EBI-11528917,EBI-373355
MIEF2 - isoform 3 [Q96C03-3]3EBI-11528917,EBI-11988931
MPP1 [Q00013]3EBI-11528917,EBI-711788
MS4A3 [Q96HJ5]3EBI-11528917,EBI-12806656
MTIF3 [Q9H2K0]3EBI-11528917,EBI-3923617
MTURN [Q8N3F0]3EBI-11528917,EBI-11980301
OCIAD1 [Q9NX40]3EBI-11528917,EBI-2683029
ODF4 [Q2M2E3]3EBI-11528917,EBI-12382569
OTULIN [Q96BN8]3EBI-11528917,EBI-750730
PDCD1LG2 [Q9BQ51]3EBI-11528917,EBI-16427978
PNKP [Q96T60]3EBI-11528917,EBI-1045072
REEP2 [Q9BRK0]3EBI-11528917,EBI-11337973
RETREG3 [Q86VR2]3EBI-11528917,EBI-10192441
S100B [A8MRB1]3EBI-11528917,EBI-16432654
SCAND1 [P57086]3EBI-11528917,EBI-745846
SCN3B [Q9NY72]3EBI-11528917,EBI-17247926
SDCBP [O00560]3EBI-11528917,EBI-727004
SENP2 [Q9HC62]3EBI-11528917,EBI-714881
SLC10A1 [Q14973]3EBI-11528917,EBI-3923031
SLC10A6 [Q3KNW5]3EBI-11528917,EBI-18159983
SLC18A1 - isoform 3 [P54219-3]3EBI-11528917,EBI-17595455
SLC34A2 - isoform 2 [O95436-2]3EBI-11528917,EBI-12811757
SLC35C2 - isoform 3 [Q9NQQ7-3]3EBI-11528917,EBI-17295964
SNX1 [Q13596]3EBI-11528917,EBI-2822329
SNX2 [O60749]3EBI-11528917,EBI-1046690
SPG21 [Q9NZD8]3EBI-11528917,EBI-742688
SSMEM1 [Q8WWF3]3EBI-11528917,EBI-17280858
SYT16 [Q17RD7]3EBI-11528917,EBI-10238936
TBRG4 [Q969Z0]3EBI-11528917,EBI-702328
TIMMDC1 [Q9NPL8]3EBI-11528917,EBI-6268651
TMEM248 [Q9NWD8]3EBI-11528917,EBI-10314986
TMX2 [Q9Y320]3EBI-11528917,EBI-6447886
TRHR [P34981]3EBI-11528917,EBI-18055230
UBASH3A - isoform 2 [P57075-2]3EBI-11528917,EBI-7353612
USP5 - isoform Short [P45974-2]3EBI-11528917,EBI-12072186

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
940453, 15 interactors

Protein interaction database and analysis system

More...
IntActi
Q8WW34, 64 interactors

Molecular INTeraction database

More...
MINTi
Q8WW34

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8WW34, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi67 – 97Trp-richAdd BLAST31
Compositional biasi101 – 181Leu-richAdd BLAST81

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502R18E, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000005090

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_125766_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8WW34

Identification of Orthologs from Complete Genome Data

More...
OMAi
PQRAVPW

Database of Orthologous Groups

More...
OrthoDBi
1571659at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8WW34

TreeFam database of animal gene trees

More...
TreeFami
TF337840

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR031694, TMEM239

The PANTHER Classification System

More...
PANTHERi
PTHR37356, PTHR37356, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15841, TMEM239, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q8WW34-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRVGTWICLP GRPGRCRKQH DLGNCPEVPG IFKTLALSPG APDMMQQPRV
60 70 80 90 100
ETDTIGAGEG PQQAVPWSAW VTRHGWVRWW VSHMPPSWIQ WWSTSNWRQP
110 120 130 140 150
LQRLLWGLEG ILYLLLALML CHALFTTGSH LLSSLWPVVA AVWRHLLPAL
160 170 180 190
LLLVLSALPA LLFTASFLLL FSTLLSLVGL LTSMTHPGDT QDLDQ
Length:195
Mass (Da):21,842
Last modified:February 19, 2014 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i56A1F7799411E2A4
GO
Isoform 2 (identifier: Q8WW34-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-43: Missing.

Show »
Length:152
Mass (Da):17,214
Checksum:i960DEC18B387FC24
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH21178 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0537371 – 43Missing in isoform 2. 1 PublicationAdd BLAST43

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK126033 mRNA Translation: BAC86404.1
AL035460 Genomic DNA No translation available.
AL161656 Genomic DNA No translation available.
CH471133 Genomic DNA Translation: EAX10573.1
BC021178 mRNA Translation: AAH21178.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS54444.1 [Q8WW34-2]
CCDS82595.1 [Q8WW34-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001161142.1, NM_001167670.2 [Q8WW34-2]
NP_001305136.1, NM_001318207.1 [Q8WW34-1]
XP_011527431.1, XM_011529129.2 [Q8WW34-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000361033; ENSP00000354312; ENSG00000198326 [Q8WW34-1]
ENST00000380585; ENSP00000369959; ENSG00000198326 [Q8WW34-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100288797

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:100288797

UCSC genome browser

More...
UCSCi
uc002wgx.3, human [Q8WW34-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK126033 mRNA Translation: BAC86404.1
AL035460 Genomic DNA No translation available.
AL161656 Genomic DNA No translation available.
CH471133 Genomic DNA Translation: EAX10573.1
BC021178 mRNA Translation: AAH21178.1 Different initiation.
CCDSiCCDS54444.1 [Q8WW34-2]
CCDS82595.1 [Q8WW34-1]
RefSeqiNP_001161142.1, NM_001167670.2 [Q8WW34-2]
NP_001305136.1, NM_001318207.1 [Q8WW34-1]
XP_011527431.1, XM_011529129.2 [Q8WW34-2]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi940453, 15 interactors
IntActiQ8WW34, 64 interactors
MINTiQ8WW34

PTM databases

iPTMnetiQ8WW34
PhosphoSitePlusiQ8WW34

Polymorphism and mutation databases

BioMutaiTMEM239
DMDMi353558900

Proteomic databases

MassIVEiQ8WW34
PaxDbiQ8WW34
PeptideAtlasiQ8WW34
PRIDEiQ8WW34
ProteomicsDBi68307
74855 [Q8WW34-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
74574, 5 antibodies

Genome annotation databases

EnsembliENST00000361033; ENSP00000354312; ENSG00000198326 [Q8WW34-1]
ENST00000380585; ENSP00000369959; ENSG00000198326 [Q8WW34-2]
GeneIDi100288797
KEGGihsa:100288797
UCSCiuc002wgx.3, human [Q8WW34-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
100288797
DisGeNETi100288797
EuPathDBiHostDB:ENSG00000198326.9

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TMEM239
HGNCiHGNC:40044, TMEM239
HPAiENSG00000198326, Tissue enriched (testis)
neXtProtiNX_Q8WW34
OpenTargetsiENSG00000198326

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502R18E, Eukaryota
GeneTreeiENSGT00390000005090
HOGENOMiCLU_125766_0_0_1
InParanoidiQ8WW34
OMAiPQRAVPW
OrthoDBi1571659at2759
PhylomeDBiQ8WW34
TreeFamiTF337840

Enzyme and pathway databases

PathwayCommonsiQ8WW34

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
100288797, 4 hits in 863 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
100288797
PharosiQ8WW34, Tdark

Protein Ontology

More...
PROi
PR:Q8WW34
RNActiQ8WW34, protein

Gene expression databases

BgeeiENSG00000198326, Expressed in left testis and 50 other tissues
GenevisibleiQ8WW34, HS

Family and domain databases

InterProiView protein in InterPro
IPR031694, TMEM239
PANTHERiPTHR37356, PTHR37356, 1 hit
PfamiView protein in Pfam
PF15841, TMEM239, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTM239_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8WW34
Secondary accession number(s): Q5JY54, Q6ZU23
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: February 19, 2014
Last modified: August 12, 2020
This is version 115 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
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