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UniProtKB - Q8WW24 (TEKT4_HUMAN)

Entry version 134 (22 Apr 2020)
Sequence version 1 (01 Mar 2002)
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Protein

Tektin-4

Gene

TEKT4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be a structural component of the sperm flagellum. Contributes to normal sperm motility.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCilium biogenesis/degradation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tektin-4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TEKT4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:31012 TEKT4

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q8WW24

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, Cilium, Flagellum

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		150483

Open Targets

More...OpenTargetsi		ENSG00000163060

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA142670819

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q8WW24 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		TEKT4

Domain mapping of disease mutations (DMDM)

More...DMDMi		74730916

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002611611 – 435Tektin-4Add BLAST435

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q8WW24

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8WW24

PeptideAtlas

More...PeptideAtlasi		Q8WW24

PRoteomics IDEntifications database

More...PRIDEi		Q8WW24

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		74851

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8WW24

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8WW24

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Strongly expressed in spermatozoa. Also detected at low levels in pancreas.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000163060 Expressed in testis and 79 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8WW24 baseline and differential

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000163060 Tissue enhanced (fallopian tube, testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q8WW24
With#Exp.IntAct
ACBD4 - isoform 3 [Q8NC06-3]3EBI-750487,EBI-12811089
AKAP8L [Q9ULX6]3EBI-750487,EBI-357530
ALAS1 [P13196]6EBI-750487,EBI-3905054
AMMECR1 - isoform 3 [Q9Y4X0-3]3EBI-750487,EBI-12823597
ANKRD55 [Q3KP44]3EBI-750487,EBI-14493093
ARID5A [Q03989]3EBI-750487,EBI-948603
ATG5 [A9UGY9]3EBI-750487,EBI-10175276
ATG5 [Q9H1Y0]6EBI-750487,EBI-1047414
BCL6 [P41182]3EBI-750487,EBI-765407
BLZF1 [Q9H2G9]3EBI-750487,EBI-2548012
C11orf1 [Q9H5F2]3EBI-750487,EBI-718615
C1orf109 [Q9NX04]3EBI-750487,EBI-8643161
CTDSP1 [Q9GZU7]3EBI-750487,EBI-751587
DDIT4L [Q96D03]3EBI-750487,EBI-742054
EFHC2 [Q5JST6]3EBI-750487,EBI-2349927
EYA2 - isoform 2 [O00167-2]3EBI-750487,EBI-12807776
FAM220A [Q7Z4H9]3EBI-750487,EBI-12871772
GATA1 - isoform 2 [P15976-2]5EBI-750487,EBI-9090198
GPSM1 - isoform 3 [Q86YR5-3]3EBI-750487,EBI-10261098
GRB10 - isoform 4 [Q13322-4]3EBI-750487,EBI-12353035
GSE1 [Q14687]5EBI-750487,EBI-372619
HCK - isoform 2 [P08631-2]3EBI-750487,EBI-9834454
HNRNPH1 [P31943]3EBI-750487,EBI-351590
HNRNPM [P52272]3EBI-750487,EBI-486809
HOXA1 [P49639]3EBI-750487,EBI-740785
HOXB5 [P09067]3EBI-750487,EBI-3893317
HOXC8 [P31273]3EBI-750487,EBI-1752118
IKZF3 [Q9UKT9]7EBI-750487,EBI-747204
INCA1 [Q0VD86]3EBI-750487,EBI-6509505
KPRP [Q5T749]3EBI-750487,EBI-10981970
KRT18 [P05783]3EBI-750487,EBI-297888
KRT34 [O76011]5EBI-750487,EBI-1047093
KRT35 [Q92764]3EBI-750487,EBI-1058674
KRT75 [O95678]3EBI-750487,EBI-2949715
KRT86 [O43790]3EBI-750487,EBI-9996498
KRTAP11-1 [Q8IUC1]3EBI-750487,EBI-1052037
KRTAP13-3 [Q3SY46]5EBI-750487,EBI-10241252
KRTAP19-1 [Q8IUB9]5EBI-750487,EBI-12811111
KRTAP19-2 [Q3LHN2]3EBI-750487,EBI-12196745
KRTAP19-6 [Q3LI70]3EBI-750487,EBI-12805508
KRTAP26-1 [Q6PEX3]3EBI-750487,EBI-3957672
KRTAP6-2 [Q3LI66]5EBI-750487,EBI-11962084
KRTAP7-1 [Q8IUC3]3EBI-750487,EBI-18394498
LASP1 - isoform 2 [Q14847-2]3EBI-750487,EBI-9088686
LMCD1 [Q9NZU5]3EBI-750487,EBI-5774016
LNX1 [Q8TBB1]3EBI-750487,EBI-739832
MAGEA4 [P43358]7EBI-750487,EBI-743122
MAGEA4 [Q1RN33]3EBI-750487,EBI-10194128
MEF2B [Q02080]3EBI-750487,EBI-6427785
MIIP [Q5JXC2]3EBI-750487,EBI-2801965
MORN3 [Q6PF18]3EBI-750487,EBI-9675802
MYOZ3 [Q8TDC0]3EBI-750487,EBI-5662487
NANOS3 - isoform 2 [P60323-2]3EBI-750487,EBI-18012223
NFKBID [Q8NI38]3EBI-750487,EBI-10271199
NR5A1 [Q13285]3EBI-750487,EBI-874629
PCSK5 - isoform PC6A [Q92824-2]3EBI-750487,EBI-11956269
PHF11 [Q9UIL8]3EBI-750487,EBI-2861403
PKP2 - isoform 1 [Q99959-2]3EBI-750487,EBI-10987518
PLAGL2 [Q9UPG8]3EBI-750487,EBI-2876622
POLDIP3 [Q8WUT1]3EBI-750487,EBI-10276663
PPP1R13B [Q96KQ4]3EBI-750487,EBI-1105153
PPP1R32 - isoform 2 [Q7Z5V6-2]6EBI-750487,EBI-12000762
PRDM14 [Q9GZV8]6EBI-750487,EBI-3957793
PRDM6 [Q9NQX0]3EBI-750487,EBI-11320284
PROP1 [O75360]3EBI-750487,EBI-9027467
PSMA1 [P25786]3EBI-750487,EBI-359352
PTH1R [Q03431]3EBI-750487,EBI-2860297
RAMAC [Q9BTL3]3EBI-750487,EBI-744023
RARA [P10276]4EBI-750487,EBI-413374
RARA - isoform Alpha-2 [P10276-2]3EBI-750487,EBI-10197061
RBM48 [Q5RL73]3EBI-750487,EBI-473821
RECK [Q6P9E2]6EBI-750487,EBI-10253121
RFX6 [Q8HWS3]3EBI-750487,EBI-746118
RUSC1 [Q9BVN2]5EBI-750487,EBI-6257312
SCN5A - isoform 3 [Q14524-3]3EBI-750487,EBI-14276801
SLC25A6 [P12236]3EBI-750487,EBI-356254
SMAD3 [P84022]3EBI-750487,EBI-347161
SMRP1 [Q8NCR6]3EBI-750487,EBI-10269322
SOCS4 [Q8WXH5]3EBI-750487,EBI-3942425
SPATA8 [Q6RVD6]3EBI-750487,EBI-8635958
SPATC1L - isoform 2 [Q9H0A9-2]3EBI-750487,EBI-11995806
SPG21 [Q9NZD8]3EBI-750487,EBI-742688
SUV39H1 [O43463]3EBI-750487,EBI-349968
TADA2A [O75478]3EBI-750487,EBI-742268
TEKT1 [Q969V4]3EBI-750487,EBI-10180409
TFAP4 [Q01664]3EBI-750487,EBI-2514218
TOX2 - isoform 3 [Q96NM4-3]3EBI-750487,EBI-12815137
TRIB3 [Q96RU7]5EBI-750487,EBI-492476
TRIP6 [Q15654]4EBI-750487,EBI-742327
TSPAN4 [O14817]3EBI-750487,EBI-8652667
UBASH3A - isoform 2 [P57075-2]3EBI-750487,EBI-7353612
USP2 [O75604]3EBI-750487,EBI-743272
VGLL1 [Q99990]3EBI-750487,EBI-11983165
ZFP90 [Q8TF47]3EBI-750487,EBI-11419867
ZIM2 [Q9NZV7]3EBI-750487,EBI-11962760
ZMYND12 [Q9H0C1]3EBI-750487,EBI-12030590
ZNF20 [P17024]3EBI-750487,EBI-717634
ZNF417 [Q8TAU3]3EBI-750487,EBI-740727
ZNF426 [Q9BUY5]3EBI-750487,EBI-743265
ZNF474 [Q6S9Z5]3EBI-750487,EBI-17269964
ZNF552 [Q9H707]3EBI-750487,EBI-2555731
ZNF581 [Q9P0T4]3EBI-750487,EBI-745520
ZNF655 [Q8N720]3EBI-750487,EBI-625509
ZNF688 [P0C7X2]3EBI-750487,EBI-4395732

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		127301, 28 interactors

Protein interaction database and analysis system

More...IntActi		Q8WW24, 116 interactors

Molecular INTeraction database

More...MINTi		Q8WW24

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000295201

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8WW24 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8WW24

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili102 – 180Sequence analysisAdd BLAST79
Coiled coili310 – 336Sequence analysisAdd BLAST27
Coiled coili363 – 411Sequence analysisAdd BLAST49

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the tektin family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2685 Eukaryota
ENOG410XSCN LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00950000182894

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_033588_2_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8WW24

KEGG Orthology (KO)

More...KOi		K18631

Identification of Orthologs from Complete Genome Data

More...OMAi		FRTAKYL

Database of Orthologous Groups

More...OrthoDBi		581072at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8WW24

TreeFam database of animal gene trees

More...TreeFami		TF320754

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000435 Tektin

The PANTHER Classification System

More...PANTHERi		PTHR19960 PTHR19960, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00511 TEKTIN

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8WW24-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAQTVPPCEL PCKEYDVARN TGAYTSSGLA TASFRTSKYL LEEWFQNCYA 
        60         70         80         90        100
RYHQAFADRD QSERQRHESQ QLATETQALA QRTQQDSTRT VGERLQDTHS 
       110        120        130        140        150
WKSELQREME ALAAETNLLL AQKQRLERAL DATEVPFSIT TDNLQCRERR 
       160        170        180        190        200
EHPNLVRDHV ETELLKEAEL IRNIQELLKR TIMQAVSQIR LNREHKETCE 
       210        220        230        240        250
MDWSDKMEAY NIDETCGRHH SQSTEVQAHP YSTTFQESAS TPETRAKFTQ 
       260        270        280        290        300
DNLCRAQRER LASANLRVLV DCILRDTSED LRLQCDAVNL AFGRRCEELE 
       310        320        330        340        350
DARYKLHHHL HKTLREITDQ EHNVAALKQA IKDKEAPLHV AQTRLYLRSH 
       360        370        380        390        400
RPNMELCRDA AQFRLLSEVE ELNMSLTALR EKLLEAEQSL RNLEDIHMSL 
       410        420        430 
EKDIAAMTNS LFIDRQKCMA HRTRYPTILQ LAGYQ
Length:435
Mass (Da):50,649
Last modified:March 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i90C16D8B0F782CED
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02908583T → M. Corresponds to variant dbSNP:rs4854235Ensembl.1
Natural variantiVAR_062151100S → G. Corresponds to variant dbSNP:rs11164112Ensembl.1
Natural variantiVAR_029086102K → N. Corresponds to variant dbSNP:rs17802433Ensembl.1
Natural variantiVAR_035941272C → S in a breast cancer sample; somatic mutation. 1 Publication1
Natural variantiVAR_029087409N → K. Corresponds to variant dbSNP:rs17120062Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AC097374 Genomic DNA Translation: AAX88873.1
BC021716 mRNA Translation: AAH21716.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS2005.1

NCBI Reference Sequences

More...RefSeqi		NP_653306.1, NM_144705.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000295201; ENSP00000295201; ENSG00000163060

Database of genes from NCBI RefSeq genomes

More...GeneIDi		150483

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:150483

UCSC genome browser

More...UCSCi		uc002stw.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC097374 Genomic DNA Translation: AAX88873.1
BC021716 mRNA Translation: AAH21716.1
CCDSiCCDS2005.1
RefSeqiNP_653306.1, NM_144705.3

3D structure databases

SMRiQ8WW24
ModBaseiSearch...

Protein-protein interaction databases

BioGridi127301, 28 interactors
IntActiQ8WW24, 116 interactors
MINTiQ8WW24
STRINGi9606.ENSP00000295201

PTM databases

iPTMnetiQ8WW24
PhosphoSitePlusiQ8WW24

Polymorphism and mutation databases

BioMutaiTEKT4
DMDMi74730916

Proteomic databases

MassIVEiQ8WW24
PaxDbiQ8WW24
PeptideAtlasiQ8WW24
PRIDEiQ8WW24
ProteomicsDBi74851

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		32286 162 antibodies

The DNASU plasmid repository

More...DNASUi		150483

Genome annotation databases

EnsembliENST00000295201; ENSP00000295201; ENSG00000163060
GeneIDi150483
KEGGihsa:150483
UCSCiuc002stw.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		150483
DisGeNETi150483

GeneCards: human genes, protein and diseases

More...GeneCardsi		TEKT4
HGNCiHGNC:31012 TEKT4
HPAiENSG00000163060 Tissue enhanced (fallopian tube, testis)
neXtProtiNX_Q8WW24
OpenTargetsiENSG00000163060
PharmGKBiPA142670819

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG2685 Eukaryota
ENOG410XSCN LUCA
GeneTreeiENSGT00950000182894
HOGENOMiCLU_033588_2_1_1
InParanoidiQ8WW24
KOiK18631
OMAiFRTAKYL
OrthoDBi581072at2759
PhylomeDBiQ8WW24
TreeFamiTF320754

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		150483
PharosiQ8WW24 Tbio

Protein Ontology

More...PROi		PR:Q8WW24
RNActiQ8WW24 protein

Gene expression databases

BgeeiENSG00000163060 Expressed in testis and 79 other tissues
ExpressionAtlasiQ8WW24 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR000435 Tektin
PANTHERiPTHR19960 PTHR19960, 1 hit
PRINTSiPR00511 TEKTIN

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTEKT4_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8WW24
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: March 1, 2002
Last modified: April 22, 2020
This is version 134 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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