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Entry version 122 (12 Aug 2020)
Sequence version 2 (18 May 2010)
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Protein

Uncharacterized protein C4orf3

Gene

C4orf3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

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PathwayCommonsi
Q8WVX3

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.A.50.6.1, the phospholamban (ca(2+)-channel and ca(2+)-atpase regulator) (plb) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein C4orf3
Alternative name(s):
Hepatitis C virus F protein-transactivated protein 1
Short name:
HCV F-transactivated protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:C4orf3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000164096.12

Human Gene Nomenclature Database

More...
HGNCi
HGNC:19225, C4orf3

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8WVX3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei45 – 65HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
401152

Open Targets

More...
OpenTargetsi
ENSG00000164096

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA164717306

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8WVX3, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
C4orf3

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003257841 – 66Uncharacterized protein C4orf3Add BLAST66

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q8WVX3

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8WVX3

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
Q8WVX3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8WVX3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8WVX3

PeptideAtlas

More...
PeptideAtlasi
Q8WVX3

PRoteomics IDEntifications database

More...
PRIDEi
Q8WVX3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
74831 [Q8WVX3-1]
74832 [Q8WVX3-2]

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q8WVX3-1 [Q8WVX3-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8WVX3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8WVX3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000164096, Expressed in epithelium of mammary gland and 231 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8WVX3, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000164096, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Isoform 2 [Q8WVX3-2]
With#Exp.IntAct
ADGRG3 [Q86Y34]3EBI-12003442,EBI-17979264
AQP6 [Q13520]3EBI-12003442,EBI-13059134
ARL13B [Q3SXY8]3EBI-12003442,EBI-11343438
BCL2L13 [Q9BXK5]5EBI-12003442,EBI-747430
BIK [Q13323]3EBI-12003442,EBI-700794
CCRL2 - isoform 2 [O00421-2]3EBI-12003442,EBI-12874086
CD79A [P11912]3EBI-12003442,EBI-7797864
CISD2 [Q8N5K1]3EBI-12003442,EBI-1045797
CLDN9 [O95484]3EBI-12003442,EBI-18341636
CREB3L1 [Q96BA8]3EBI-12003442,EBI-6942903
CXCR2 [P25025]3EBI-12003442,EBI-2835281
CYBC1 [Q9BQA9]3EBI-12003442,EBI-2680384
DEGS1 [O15121]3EBI-12003442,EBI-1052713
EBP [Q15125]3EBI-12003442,EBI-3915253
ERGIC3 [Q9Y282]3EBI-12003442,EBI-781551
FAM174A [Q8TBP5]3EBI-12003442,EBI-18636064
FAM209A [Q5JX71]3EBI-12003442,EBI-18304435
FFAR2 [O15552]3EBI-12003442,EBI-2833872
GJA5 [P36382]3EBI-12003442,EBI-750433
GJB4 [Q9NTQ9]3EBI-12003442,EBI-12831526
GJB5 [O95377]3EBI-12003442,EBI-3909454
GPR61 [Q9BZJ8]3EBI-12003442,EBI-12808020
HHATL [Q9HCP6]3EBI-12003442,EBI-5916693
JAGN1 [Q8N5M9]3EBI-12003442,EBI-10266796
LAPTM5 [Q13571]3EBI-12003442,EBI-2865663
LY6G6C [O95867]3EBI-12003442,EBI-9088345
MFSD14B [Q5SR56]3EBI-12003442,EBI-373355
MILR1 [Q7Z6M3]3EBI-12003442,EBI-18391669
MMD [Q15546]3EBI-12003442,EBI-17873222
MMGT1 [Q8N4V1]3EBI-12003442,EBI-6163737
MRM3 [Q9HC36]3EBI-12003442,EBI-1045440
MS4A3 [Q96HJ5]3EBI-12003442,EBI-12806656
NCAPH2 - isoform 4 [Q6IBW4-4]3EBI-12003442,EBI-10247000
PLEKHO1 [Q53GL0]3EBI-12003442,EBI-949945
PTGES [O14684]3EBI-12003442,EBI-11161398
REEP4 [Q9H6H4]3EBI-12003442,EBI-7545592
RETREG3 [Q86VR2]3EBI-12003442,EBI-10192441
RHBDL1 [O75783]3EBI-12003442,EBI-12104986
RHCG [Q9UBD6]3EBI-12003442,EBI-15853497
SHISAL1 [Q3SXP7]3EBI-12003442,EBI-18037857
SLC14A2 [Q15849]3EBI-12003442,EBI-1573290
SLC19A3 [Q9BZV2]3EBI-12003442,EBI-3923779
SLC35C2 - isoform 3 [Q9NQQ7-3]3EBI-12003442,EBI-17295964
SLC35E3 [Q7Z769]3EBI-12003442,EBI-13389236
SLC39A2 [Q9NP94]3EBI-12003442,EBI-12898013
SLC41A3 [Q96GZ6]3EBI-12003442,EBI-7225508
SLCO3A1 - isoform 2 [Q9UIG8-2]3EBI-12003442,EBI-13041931
SSMEM1 [Q8WWF3]3EBI-12003442,EBI-17280858
STX1A [Q16623]3EBI-12003442,EBI-712466
SYNPR [Q8TBG9]3EBI-12003442,EBI-10273251
TIMMDC1 [Q9NPL8]3EBI-12003442,EBI-6268651
TM4SF19 [Q96DZ7]3EBI-12003442,EBI-6448756
TMEM101 [Q96IK0]3EBI-12003442,EBI-3922699
TMEM237 - isoform 2 [Q96Q45-2]3EBI-12003442,EBI-10982110
TMEM248 [Q9NWD8]3EBI-12003442,EBI-10314986
TMEM45A [Q9NWC5]3EBI-12003442,EBI-10823938
TMEM45B [Q96B21]3EBI-12003442,EBI-3923061
TMEM51 [Q9NW97]3EBI-12003442,EBI-726044
YIF1A [O95070]3EBI-12003442,EBI-2799703

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
134952, 10 interactors

Protein interaction database and analysis system

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IntActi
Q8WVX3, 67 interactors

Molecular INTeraction database

More...
MINTi
Q8WVX3

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000382026

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8WVX3, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q8WVX3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG502T0GP, Eukaryota

Ensembl GeneTree

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GeneTreei
ENSGT00530000064570

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_135965_0_0_1

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q8WVX3

Identification of Orthologs from Complete Genome Data

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OMAi
PRRKHDI

Database of Orthologous Groups

More...
OrthoDBi
1307860at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8WVX3

TreeFam database of animal gene trees

More...
TreeFami
TF343305

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR038780, C4orf3

The PANTHER Classification System

More...
PANTHERi
PTHR37367, PTHR37367, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF17696, DUF5542, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q8WVX3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEVDAPGVDG RDGLRERRGF SEGGRQNFDV RPQSGANGLP KHSYWLDLWL
60
FILFDVVVFL FVYFLP
Length:66
Mass (Da):7,604
Last modified:May 18, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6973371B80AE75CC
GO
Isoform 2 (identifier: Q8WVX3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MTSLINSPIN...GLLRSCRSEM

Show »
Length:199
Mass (Da):22,558
Checksum:i78988F83DB793925
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03991117R → Q1 PublicationCorresponds to variant dbSNP:rs17851522Ensembl.1
Natural variantiVAR_03991232P → H. Corresponds to variant dbSNP:rs11544530Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0324051M → MTSLINSPINRRPLQNVEGN NRCQRKAKNYGNKYFIHCLD LEKITLSPRRKHDIEGGDKL NVKFSQLRSRRQRKAEPGAC ALGRVGSECIPEPGARRTAQ AAGLRSVSGAANTKVRELKH FRFLGLLRSCRSEM in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY605045 mRNA Translation: AAT35812.1
AC092656 Genomic DNA No translation available.
BC017399 mRNA Translation: AAH17399.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS43266.1 [Q8WVX3-1]
CCDS54798.1 [Q8WVX3-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001001701.2, NM_001001701.3 [Q8WVX3-1]
NP_001163801.1, NM_001170330.1 [Q8WVX3-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000399075; ENSP00000382026; ENSG00000164096 [Q8WVX3-2]
ENST00000504110; ENSP00000485697; ENSG00000164096 [Q8WVX3-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
401152

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:401152

UCSC genome browser

More...
UCSCi
uc003icv.5, human [Q8WVX3-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY605045 mRNA Translation: AAT35812.1
AC092656 Genomic DNA No translation available.
BC017399 mRNA Translation: AAH17399.1
CCDSiCCDS43266.1 [Q8WVX3-1]
CCDS54798.1 [Q8WVX3-2]
RefSeqiNP_001001701.2, NM_001001701.3 [Q8WVX3-1]
NP_001163801.1, NM_001170330.1 [Q8WVX3-2]

3D structure databases

SMRiQ8WVX3
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi134952, 10 interactors
IntActiQ8WVX3, 67 interactors
MINTiQ8WVX3
STRINGi9606.ENSP00000382026

Protein family/group databases

TCDBi1.A.50.6.1, the phospholamban (ca(2+)-channel and ca(2+)-atpase regulator) (plb) family

PTM databases

iPTMnetiQ8WVX3
PhosphoSitePlusiQ8WVX3

Polymorphism and mutation databases

BioMutaiC4orf3

Proteomic databases

EPDiQ8WVX3
jPOSTiQ8WVX3
MassIVEiQ8WVX3
MaxQBiQ8WVX3
PaxDbiQ8WVX3
PeptideAtlasiQ8WVX3
PRIDEiQ8WVX3
ProteomicsDBi74831 [Q8WVX3-1]
74832 [Q8WVX3-2]
TopDownProteomicsiQ8WVX3-1 [Q8WVX3-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
26668, 81 antibodies

The DNASU plasmid repository

More...
DNASUi
401152

Genome annotation databases

EnsembliENST00000399075; ENSP00000382026; ENSG00000164096 [Q8WVX3-2]
ENST00000504110; ENSP00000485697; ENSG00000164096 [Q8WVX3-1]
GeneIDi401152
KEGGihsa:401152
UCSCiuc003icv.5, human [Q8WVX3-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
401152
DisGeNETi401152
EuPathDBiHostDB:ENSG00000164096.12

GeneCards: human genes, protein and diseases

More...
GeneCardsi
C4orf3
HGNCiHGNC:19225, C4orf3
HPAiENSG00000164096, Low tissue specificity
neXtProtiNX_Q8WVX3
OpenTargetsiENSG00000164096
PharmGKBiPA164717306

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502T0GP, Eukaryota
GeneTreeiENSGT00530000064570
HOGENOMiCLU_135965_0_0_1
InParanoidiQ8WVX3
OMAiPRRKHDI
OrthoDBi1307860at2759
PhylomeDBiQ8WVX3
TreeFamiTF343305

Enzyme and pathway databases

PathwayCommonsiQ8WVX3

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
401152, 1 hit in 871 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
C4orf3, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
401152
PharosiQ8WVX3, Tdark

Protein Ontology

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PROi
PR:Q8WVX3
RNActiQ8WVX3, protein

Gene expression databases

BgeeiENSG00000164096, Expressed in epithelium of mammary gland and 231 other tissues
GenevisibleiQ8WVX3, HS

Family and domain databases

InterProiView protein in InterPro
IPR038780, C4orf3
PANTHERiPTHR37367, PTHR37367, 1 hit
PfamiView protein in Pfam
PF17696, DUF5542, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCD003_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8WVX3
Secondary accession number(s): Q6J203
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: May 18, 2010
Last modified: August 12, 2020
This is version 122 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
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