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Entry version 121 (16 Oct 2019)
Sequence version 4 (13 Jul 2010)
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Protein

Protein OSCP1

Gene

OSCP1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in drug clearance in the placenta.1 Publication

Miscellaneous

May be involved in the development and/or progression of nosopharyngeal carcinoma.

Caution

The polymorphism 'Glu58Gly' (described in PubMed:12819961) is in fact an error, the G to A change described representing a synonymous mutation that does not induce any amino acid change in Gly-32.Curated

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

In Xenopus laevis oocytes, in a sodium-independent manner.
  1. KM=35.0 µM for p-aminohippurate (PAH)1 Publication
  2. KM=62.3 µM for tetraethylammonium1 Publication

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    • transmembrane transporter activity Source: UniProtKB

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Biological processTransport

    Protein family/group databases

    Transport Classification Database

    More...
    TCDBi
    9.B.68.1.1 the putative na-independent organic solute carrier protein (oscp1) family

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Protein OSCP1
    Short name:
    hOSCP1
    Alternative name(s):
    Organic solute transport protein 1
    Oxidored-nitro domain-containing protein 1
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:OSCP1
    Synonyms:C1orf102, NOR1
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

    Organism-specific databases

    Human Gene Nomenclature Database

    More...
    HGNCi
    HGNC:29971 OSCP1

    Online Mendelian Inheritance in Man (OMIM)

    More...
    MIMi
    608854 gene

    neXtProt; the human protein knowledge platform

    More...
    neXtProti
    NX_Q8WVF1

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

    Keywords - Cellular componenti

    Cell membrane, Membrane

    <p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

    Organism-specific databases

    DisGeNET

    More...
    DisGeNETi
    127700

    Open Targets

    More...
    OpenTargetsi
    ENSG00000116885

    The Pharmacogenetics and Pharmacogenomics Knowledge Base

    More...
    PharmGKBi
    PA165752125

    Miscellaneous databases

    Pharos NIH Druggable Genome Knowledgebase

    More...
    Pharosi
    Q8WVF1

    Polymorphism and mutation databases

    BioMuta curated single-nucleotide variation and disease association database

    More...
    BioMutai
    OSCP1

    Domain mapping of disease mutations (DMDM)

    More...
    DMDMi
    300669715

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002519651 – 389Protein OSCP1Add BLAST389

    Proteomic databases

    MassIVE - Mass Spectrometry Interactive Virtual Environment

    More...
    MassIVEi
    Q8WVF1

    MaxQB - The MaxQuant DataBase

    More...
    MaxQBi
    Q8WVF1

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    Q8WVF1

    PeptideAtlas

    More...
    PeptideAtlasi
    Q8WVF1

    PRoteomics IDEntifications database

    More...
    PRIDEi
    Q8WVF1

    ProteomicsDB: a multi-organism proteome resource

    More...
    ProteomicsDBi
    74786 [Q8WVF1-1]
    74787 [Q8WVF1-2]
    74788 [Q8WVF1-3]
    74789 [Q8WVF1-4]

    PTM databases

    iPTMnet integrated resource for PTMs in systems biology context

    More...
    iPTMneti
    Q8WVF1

    Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

    More...
    PhosphoSitePlusi
    Q8WVF1

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    <p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

    Expressed predominantly in testis, also found in placenta and to a lesser extent in thymus and small intestine; abundantly expressed in tumor-derived cell lines (PubMed:16006562). Ubiquitously expressed (PubMed:12819961).2 Publications

    Gene expression databases

    Bgee dataBase for Gene Expression Evolution

    More...
    Bgeei
    ENSG00000116885 Expressed in 92 organ(s), highest expression level in right testis

    ExpressionAtlas, Differential and Baseline Expression

    More...
    ExpressionAtlasi
    Q8WVF1 baseline and differential

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...
    Genevisiblei
    Q8WVF1 HS

    Organism-specific databases

    Human Protein Atlas

    More...
    HPAi
    HPA028436
    HPA052655

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    Protein-protein interaction databases

    The Biological General Repository for Interaction Datasets (BioGrid)

    More...
    BioGridi
    126078, 5 interactors

    Protein interaction database and analysis system

    More...
    IntActi
    Q8WVF1, 5 interactors

    STRING: functional protein association networks

    More...
    STRINGi
    9606.ENSP00000235532

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    KOG4033 Eukaryota
    ENOG41107FG LUCA

    Ensembl GeneTree

    More...
    GeneTreei
    ENSGT00390000004808

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    Q8WVF1

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    LIEMYTP

    Database of Orthologous Groups

    More...
    OrthoDBi
    1398008at2759

    Database for complete collections of gene phylogenies

    More...
    PhylomeDBi
    Q8WVF1

    TreeFam database of animal gene trees

    More...
    TreeFami
    TF105789

    Family and domain databases

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR019332 OSCP1

    The PANTHER Classification System

    More...
    PANTHERi
    PTHR21439 PTHR21439, 1 hit

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF10188 Oscp1, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

    This entry has 4 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

    Isoform 1 (identifier: Q8WVF1-1) [UniParc]FASTAAdd to basket

    This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide
            10         20         30         40         50
    MSVRTLPLLF LNLGGEMLYI LDQRLRAQNI PGDKARKDEW TEVDRKRVLN
    60 70 80 90 100
    DIISTMFNRK FMEELFKPQE LYSKKALRTV YERLAHASIM KLNQASMDKL
    110 120 130 140 150
    YDLMTMAFKY QVLLCPRPKD VLLVTFNHLD TIKGFIRDSP TILQQVDETL
    160 170 180 190 200
    RQLTEIYGGL SAGEFQLIRQ TLLIFFQDLH IRVSMFLKDK VQNNNGRFVL
    210 220 230 240 250
    PVSGPVPWGT EVPGLIRMFN NKGEEVKRIE FKHGGNYVPA PKEGSFELYG
    260 270 280 290 300
    DRVLKLGTNM YSVNQPVETH VSGSSKNLAS WTQESIAPNP LAKEELNFLA
    310 320 330 340 350
    RLMGGMEIKK PSGPEPGFRL NLFTTDEEEE QAALTRPEEL SYEVINIQAT
    360 370 380
    QDQQRSEELA RIMGEFEITE QPRLSTSKGD DLLAMMDEL
    Length:389
    Mass (Da):44,586
    Last modified:July 13, 2010 - v4
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8EA5C1EF2D9973F4
    GO
    Isoform 2 (identifier: Q8WVF1-2) [UniParc]FASTAAdd to basket

    The sequence of this isoform differs from the canonical sequence as follows:
         329-378: Missing.

    Note: No experimental confirmation available.
    Show »
    Length:339
    Mass (Da):38,810
    Checksum:iA275B77A753D79D1
    GO
    Isoform 3 (identifier: Q8WVF1-3) [UniParc]FASTAAdd to basket

    The sequence of this isoform differs from the canonical sequence as follows:
         38-47: Missing.

    Show »
    Length:379
    Mass (Da):43,271
    Checksum:iB233ECE9C1E46F08
    GO
    Isoform 4 (identifier: Q8WVF1-4) [UniParc]FASTAAdd to basket

    The sequence of this isoform differs from the canonical sequence as follows:
         38-47: Missing.
         183-231: VSMFLKDKVQ...KGEEVKRIEF → RECFWKHMQE...ENFEFCTWAK
         232-389: Missing.

    Show »
    Length:223
    Mass (Da):26,431
    Checksum:i769226B3771F756D
    GO

    <p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

    There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
    EntryEntry nameProtein names
    Gene namesLengthAnnotation
    C9JF58C9JF58_HUMAN
    Protein OSCP1
    OSCP1
    334Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    H7C0S2H7C0S2_HUMAN
    Protein OSCP1
    OSCP1
    255Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    H0YAG0H0YAG0_HUMAN
    Protein OSCP1
    OSCP1
    94Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    H0YDT3H0YDT3_HUMAN
    Protein OSCP1
    OSCP1
    13Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

    <p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

    The sequence AAL89738 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

    Experimental Info

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti51D → G in BAC05326 (PubMed:14702039).Curated1
    Sequence conflicti317G → R in BAE16984 (PubMed:16006562).Curated1
    Sequence conflicti377S → G in AAL89738 (PubMed:12819961).Curated1
    Sequence conflicti377S → G in AAH18069 (Ref. 5) Curated1

    Natural variant

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02774131P → R2 PublicationsCorresponds to variant dbSNP:rs11547025Ensembl.1
    Natural variantiVAR_056958141T → A1 PublicationCorresponds to variant dbSNP:rs34409118Ensembl.1
    Natural variantiVAR_027742242K → E. Corresponds to variant dbSNP:rs2359016Ensembl.1

    Alternative sequence

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_03947538 – 47Missing in isoform 3 and isoform 4. 3 Publications10
    Alternative sequenceiVSP_039476183 – 231VSMFL…KRIEF → RECFWKHMQETVHSAQCCLP GVGNYMEDRRRRLTFHYVYP FENFEFCTWAK in isoform 4. CuratedAdd BLAST49
    Alternative sequenceiVSP_039477232 – 389Missing in isoform 4. CuratedAdd BLAST158
    Alternative sequenceiVSP_020826329 – 378Missing in isoform 2. 1 PublicationAdd BLAST50

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    AF462348 mRNA Translation: AAL89738.1 Different initiation.
    AB079075 mRNA Translation: BAE16984.1
    AK098541 mRNA Translation: BAC05326.1
    AC119675 Genomic DNA No translation available.
    CH471059 Genomic DNA Translation: EAX07365.1
    BC018069 mRNA Translation: AAH18069.2

    The Consensus CDS (CCDS) project

    More...
    CCDSi
    CCDS409.2 [Q8WVF1-3]
    CCDS410.1 [Q8WVF1-4]
    CCDS81301.1 [Q8WVF1-1]

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_001317422.1, NM_001330493.1 [Q8WVF1-1]
    NP_659484.4, NM_145047.4 [Q8WVF1-3]
    NP_996668.1, NM_206837.2 [Q8WVF1-4]

    Genome annotation databases

    Ensembl eukaryotic genome annotation project

    More...
    Ensembli
    ENST00000235532; ENSP00000235532; ENSG00000116885 [Q8WVF1-3]
    ENST00000354267; ENSP00000346216; ENSG00000116885 [Q8WVF1-4]
    ENST00000356637; ENSP00000349052; ENSG00000116885 [Q8WVF1-1]

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    127700

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    hsa:127700

    UCSC genome browser

    More...
    UCSCi
    uc001caq.4 human [Q8WVF1-1]

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AF462348 mRNA Translation: AAL89738.1 Different initiation.
    AB079075 mRNA Translation: BAE16984.1
    AK098541 mRNA Translation: BAC05326.1
    AC119675 Genomic DNA No translation available.
    CH471059 Genomic DNA Translation: EAX07365.1
    BC018069 mRNA Translation: AAH18069.2
    CCDSiCCDS409.2 [Q8WVF1-3]
    CCDS410.1 [Q8WVF1-4]
    CCDS81301.1 [Q8WVF1-1]
    RefSeqiNP_001317422.1, NM_001330493.1 [Q8WVF1-1]
    NP_659484.4, NM_145047.4 [Q8WVF1-3]
    NP_996668.1, NM_206837.2 [Q8WVF1-4]

    3D structure databases

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    SWISS-MODEL Interactive Workspace

    More...
    SWISS-MODEL-Workspacei
    Submit a new modelling project...

    Protein-protein interaction databases

    BioGridi126078, 5 interactors
    IntActiQ8WVF1, 5 interactors
    STRINGi9606.ENSP00000235532

    Protein family/group databases

    TCDBi9.B.68.1.1 the putative na-independent organic solute carrier protein (oscp1) family

    PTM databases

    iPTMnetiQ8WVF1
    PhosphoSitePlusiQ8WVF1

    Polymorphism and mutation databases

    BioMutaiOSCP1
    DMDMi300669715

    Proteomic databases

    MassIVEiQ8WVF1
    MaxQBiQ8WVF1
    PaxDbiQ8WVF1
    PeptideAtlasiQ8WVF1
    PRIDEiQ8WVF1
    ProteomicsDBi74786 [Q8WVF1-1]
    74787 [Q8WVF1-2]
    74788 [Q8WVF1-3]
    74789 [Q8WVF1-4]

    Protocols and materials databases

    The DNASU plasmid repository

    More...
    DNASUi
    127700

    Genome annotation databases

    EnsembliENST00000235532; ENSP00000235532; ENSG00000116885 [Q8WVF1-3]
    ENST00000354267; ENSP00000346216; ENSG00000116885 [Q8WVF1-4]
    ENST00000356637; ENSP00000349052; ENSG00000116885 [Q8WVF1-1]
    GeneIDi127700
    KEGGihsa:127700
    UCSCiuc001caq.4 human [Q8WVF1-1]

    Organism-specific databases

    Comparative Toxicogenomics Database

    More...
    CTDi
    127700
    DisGeNETi127700

    GeneCards: human genes, protein and diseases

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    GeneCardsi
    OSCP1
    HGNCiHGNC:29971 OSCP1
    HPAiHPA028436
    HPA052655
    MIMi608854 gene
    neXtProtiNX_Q8WVF1
    OpenTargetsiENSG00000116885
    PharmGKBiPA165752125

    GenAtlas: human gene database

    More...
    GenAtlasi
    Search...

    Phylogenomic databases

    eggNOGiKOG4033 Eukaryota
    ENOG41107FG LUCA
    GeneTreeiENSGT00390000004808
    InParanoidiQ8WVF1
    OMAiLIEMYTP
    OrthoDBi1398008at2759
    PhylomeDBiQ8WVF1
    TreeFamiTF105789

    Miscellaneous databases

    ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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    ChiTaRSi
    OSCP1 human

    Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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    GenomeRNAii
    127700
    PharosiQ8WVF1

    Protein Ontology

    More...
    PROi
    PR:Q8WVF1

    The Stanford Online Universal Resource for Clones and ESTs

    More...
    SOURCEi
    Search...

    Gene expression databases

    BgeeiENSG00000116885 Expressed in 92 organ(s), highest expression level in right testis
    ExpressionAtlasiQ8WVF1 baseline and differential
    GenevisibleiQ8WVF1 HS

    Family and domain databases

    InterProiView protein in InterPro
    IPR019332 OSCP1
    PANTHERiPTHR21439 PTHR21439, 1 hit
    PfamiView protein in Pfam
    PF10188 Oscp1, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiOSCP1_HUMAN
    <p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8WVF1
    Secondary accession number(s): A6NHM5
    , A6NHS9, A6NIN9, Q4AEJ0, Q8N7G2, Q8TDF1
    <p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
    Last sequence update: July 13, 2010
    Last modified: October 16, 2019
    This is version 121 of the entry and version 4 of the sequence. See complete history.
    <p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    <p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. Human chromosome 1
      Human chromosome 1: entries, gene names and cross-references to MIM
    4. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
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