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UniProtKB - Q8WVC6 (DCAKD_HUMAN)

Entry version 152 (02 Dec 2020)
Sequence version 1 (01 Mar 2002)
Previous versions | rss
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Protein

Dephospho-CoA kinase domain-containing protein

Gene

DCAKD

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi8 – 15ATPSequence analysis8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q8WVC6

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Dephospho-CoA kinase domain-containing protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DCAKD
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...EuPathDBi		HostDB:ENSG00000172992.11

Human Gene Nomenclature Database

More...HGNCi		HGNC:26238, DCAKD

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q8WVC6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000172992

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA142672013

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q8WVC6, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		DCAKD

Domain mapping of disease mutations (DMDM)

More...DMDMi		74730834

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003168491 – 231Dephospho-CoA kinase domain-containing proteinAdd BLAST231

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q8WVC6

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q8WVC6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q8WVC6

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q8WVC6

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8WVC6

PeptideAtlas

More...PeptideAtlasi		Q8WVC6

PRoteomics IDEntifications database

More...PRIDEi		Q8WVC6

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		74776 [Q8WVC6-1]
74777 [Q8WVC6-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8WVC6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8WVC6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000172992, Expressed in subventricular zone (inner) (primate) and 190 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8WVC6, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8WVC6, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000172992, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		122965, 35 interactors

Protein interaction database and analysis system

More...IntActi		Q8WVC6, 17 interactors

Molecular INTeraction database

More...MINTi		Q8WVC6

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000308515

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8WVC6, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8WVC6

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini3 – 207DPCKAdd BLAST205

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CoaE family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3220, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00550000075038

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8WVC6

Identification of Orthologs from Complete Genome Data

More...OMAi		QMDIEQK

Database of Orthologous Groups

More...OrthoDBi		1263008at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8WVC6

TreeFam database of animal gene trees

More...TreeFami		TF314815

Family and domain databases

HAMAP database of protein families

More...HAMAPi		MF_00376, Dephospho_CoA_kinase, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001977, Depp_CoAkinase
IPR027417, P-loop_NTPase

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01121, CoaE, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52540, SSF52540, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00152, TIGR00152, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51219, DPCK, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8WVC6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MFLVGLTGGI ASGKSSVIQV FQQLGCAVID VDVMARHVVQ PGYPAHRRIV 
        60         70         80         90        100
EVFGTEVLLE NGDINRKVLG DLIFNQPDRR QLLNAITHPE IRKEMMKETF 
       110        120        130        140        150
KYFLRGYRYV ILDIPLLFET KKLLKYMKHT VVVYCDRDTQ LARLMRRNSL 
       160        170        180        190        200
NRKDAEARIN AQLPLTDKAR MARHVLDNSG EWSVTKRQVI LLHTELERSL 
       210        220        230 
EYLPLRFGVL TGLAAIASLL YLLTHYLLPY A
Length:231
Mass (Da):26,550
Last modified:March 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE3AE93E8E3962544
GO
Isoform 2 (identifier: Q8WVC6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     106-132: GYRYVILDIPLLFETKKLLKYMKHTVV → EPRTSPRGKKHVPSALKEADSLMRRDT
     133-231: Missing.

Show »
Length:132
Mass (Da):14,927
Checksum:i33228A5A74EDA3AF
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7ESP4K7ESP4_HUMAN
Dephospho-CoA kinase domain-contain...
DCAKD
209Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti218S → N in BAF83444 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03840684N → I1 PublicationCorresponds to variant dbSNP:rs17850104Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_030810106 – 132GYRYV…KHTVV → EPRTSPRGKKHVPSALKEAD SLMRRDT in isoform 2. 1 PublicationAdd BLAST27
Alternative sequenceiVSP_030811133 – 231Missing in isoform 2. 1 PublicationAdd BLAST99

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK026608 mRNA Translation: BAB15508.1
AK290755 mRNA Translation: BAF83444.1
CH471178 Genomic DNA Translation: EAW51558.1
CH471178 Genomic DNA Translation: EAW51559.1
CH471178 Genomic DNA Translation: EAW51560.1
CH471178 Genomic DNA Translation: EAW51561.1
CH471178 Genomic DNA Translation: EAW51562.1
BC006472 mRNA Translation: AAH06472.1
BC006546 mRNA Translation: AAH06546.1
BC018132 mRNA Translation: AAH18132.1
BC033299 mRNA Translation: AAH33299.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS11493.1 [Q8WVC6-1]

NCBI Reference Sequences

More...RefSeqi		NP_001122103.1, NM_001128631.2 [Q8WVC6-1]
NP_001275583.1, NM_001288654.2 [Q8WVC6-1]
NP_001275584.1, NM_001288655.1 [Q8WVC6-1]
NP_001308255.1, NM_001321326.1 [Q8WVC6-1]
NP_079095.3, NM_024819.6 [Q8WVC6-1]
XP_005257745.1, XM_005257688.2 [Q8WVC6-2]
XP_011523564.1, XM_011525262.2 [Q8WVC6-1]
XP_016880591.1, XM_017025102.1
XP_016880592.1, XM_017025103.1 [Q8WVC6-2]
XP_016880593.1, XM_017025104.1 [Q8WVC6-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000310604; ENSP00000308515; ENSG00000172992 [Q8WVC6-1]
ENST00000342350; ENSP00000341504; ENSG00000172992 [Q8WVC6-1]
ENST00000452796; ENSP00000413483; ENSG00000172992 [Q8WVC6-1]
ENST00000588499; ENSP00000467913; ENSG00000172992 [Q8WVC6-1]
ENST00000614054; ENSP00000478909; ENSG00000172992 [Q8WVC6-1]
ENST00000651974; ENSP00000498268; ENSG00000172992 [Q8WVC6-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		79877

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:79877

UCSC genome browser

More...UCSCi		uc002ihx.3, human [Q8WVC6-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK026608 mRNA Translation: BAB15508.1
AK290755 mRNA Translation: BAF83444.1
CH471178 Genomic DNA Translation: EAW51558.1
CH471178 Genomic DNA Translation: EAW51559.1
CH471178 Genomic DNA Translation: EAW51560.1
CH471178 Genomic DNA Translation: EAW51561.1
CH471178 Genomic DNA Translation: EAW51562.1
BC006472 mRNA Translation: AAH06472.1
BC006546 mRNA Translation: AAH06546.1
BC018132 mRNA Translation: AAH18132.1
BC033299 mRNA Translation: AAH33299.1
CCDSiCCDS11493.1 [Q8WVC6-1]
RefSeqiNP_001122103.1, NM_001128631.2 [Q8WVC6-1]
NP_001275583.1, NM_001288654.2 [Q8WVC6-1]
NP_001275584.1, NM_001288655.1 [Q8WVC6-1]
NP_001308255.1, NM_001321326.1 [Q8WVC6-1]
NP_079095.3, NM_024819.6 [Q8WVC6-1]
XP_005257745.1, XM_005257688.2 [Q8WVC6-2]
XP_011523564.1, XM_011525262.2 [Q8WVC6-1]
XP_016880591.1, XM_017025102.1
XP_016880592.1, XM_017025103.1 [Q8WVC6-2]
XP_016880593.1, XM_017025104.1 [Q8WVC6-2]

3D structure databases

SMRiQ8WVC6
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi122965, 35 interactors
IntActiQ8WVC6, 17 interactors
MINTiQ8WVC6
STRINGi9606.ENSP00000308515

PTM databases

iPTMnetiQ8WVC6
PhosphoSitePlusiQ8WVC6

Polymorphism and mutation databases

BioMutaiDCAKD
DMDMi74730834

Proteomic databases

EPDiQ8WVC6
jPOSTiQ8WVC6
MassIVEiQ8WVC6
MaxQBiQ8WVC6
PaxDbiQ8WVC6
PeptideAtlasiQ8WVC6
PRIDEiQ8WVC6
ProteomicsDBi74776 [Q8WVC6-1]
74777 [Q8WVC6-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		29945, 170 antibodies

The DNASU plasmid repository

More...DNASUi		79877

Genome annotation databases

EnsembliENST00000310604; ENSP00000308515; ENSG00000172992 [Q8WVC6-1]
ENST00000342350; ENSP00000341504; ENSG00000172992 [Q8WVC6-1]
ENST00000452796; ENSP00000413483; ENSG00000172992 [Q8WVC6-1]
ENST00000588499; ENSP00000467913; ENSG00000172992 [Q8WVC6-1]
ENST00000614054; ENSP00000478909; ENSG00000172992 [Q8WVC6-1]
ENST00000651974; ENSP00000498268; ENSG00000172992 [Q8WVC6-1]
GeneIDi79877
KEGGihsa:79877
UCSCiuc002ihx.3, human [Q8WVC6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		79877
EuPathDBiHostDB:ENSG00000172992.11

GeneCards: human genes, protein and diseases

More...GeneCardsi		DCAKD
HGNCiHGNC:26238, DCAKD
HPAiENSG00000172992, Low tissue specificity
neXtProtiNX_Q8WVC6
OpenTargetsiENSG00000172992
PharmGKBiPA142672013

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3220, Eukaryota
GeneTreeiENSGT00550000075038
InParanoidiQ8WVC6
OMAiQMDIEQK
OrthoDBi1263008at2759
PhylomeDBiQ8WVC6
TreeFamiTF314815

Enzyme and pathway databases

PathwayCommonsiQ8WVC6

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		79877, 5 hits in 844 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		DCAKD, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		79877
PharosiQ8WVC6, Tdark

Protein Ontology

More...PROi		PR:Q8WVC6
RNActiQ8WVC6, protein

Gene expression databases

BgeeiENSG00000172992, Expressed in subventricular zone (inner) (primate) and 190 other tissues
ExpressionAtlasiQ8WVC6, baseline and differential
GenevisibleiQ8WVC6, HS

Family and domain databases

HAMAPiMF_00376, Dephospho_CoA_kinase, 1 hit
InterProiView protein in InterPro
IPR001977, Depp_CoAkinase
IPR027417, P-loop_NTPase
PfamiView protein in Pfam
PF01121, CoaE, 1 hit
SUPFAMiSSF52540, SSF52540, 1 hit
TIGRFAMsiTIGR00152, TIGR00152, 1 hit
PROSITEiView protein in PROSITE
PS51219, DPCK, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDCAKD_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8WVC6
Secondary accession number(s): A8K3Z0
, D3DX60, D3DX62, Q9BR71, Q9H5W1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: March 1, 2002
Last modified: December 2, 2020
This is version 152 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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