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Entry version 106 (08 May 2019)
Sequence version 1 (01 Mar 2002)
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Protein

Protein FAM222B

Gene

FAM222B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
Q8WU58

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein FAM222B
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM222B
Synonyms:C17orf63
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25563 FAM222B

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8WU58

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
55731

Open Targets

More...
OpenTargetsi
ENSG00000173065

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142672246

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM222B

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74730670

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002742451 – 562Protein FAM222BAdd BLAST562

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q8WU58

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8WU58

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8WU58

PeptideAtlas

More...
PeptideAtlasi
Q8WU58

PRoteomics IDEntifications database

More...
PRIDEi
Q8WU58

ProteomicsDB human proteome resource

More...
ProteomicsDBi
74633

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8WU58

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8WU58

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000173065 Expressed in 235 organ(s), highest expression level in sperm

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8WU58 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8WU58 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA051840
HPA062239

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
120850, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q8WU58, 39 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000462419

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi148 – 220Gln-richAdd BLAST73

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAM222 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IEMV Eukaryota
ENOG410YNEB LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063811

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000111757

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8WU58

Identification of Orthologs from Complete Genome Data

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OMAi
HLQQMCG

Database of Orthologous Groups

More...
OrthoDBi
379104at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8WU58

TreeFam database of animal gene trees

More...
TreeFami
TF331508

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029340 FAM222

The PANTHER Classification System

More...
PANTHERi
PTHR16070 PTHR16070, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15258 FAM222A, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

Q8WU58-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLACLPGPGD LSFQLLSHTQ MNTGLQKWDT TQKMRTAHYP TPAELDAYAK
60 70 80 90 100
KVANNPLTIK IFPNSVKVPQ RKHVRRTVNG LDTSAQRYSP YPTQAATKAG
110 120 130 140 150
LLAIVKVPAK SILKDFDGTR ARLLPEAIMN PPVAPYATVA PSTLAHPQAQ
160 170 180 190 200
ALARQQALQH AQTLAHAPPQ TLQHPQGIPP PQALSHPQSL QQPQGLGHPQ
210 220 230 240 250
PMAQTQGLVH PQALAHQGLQ HPHNPLLHGG RKMPDSDAPP NVTVSTSTIP
260 270 280 290 300
LSMAATLQHS QPPDLSSIVH QINQFCQTRA GISTTSVCEG QIANPSPISR
310 320 330 340 350
SLLINASTRV STHSVPTPMP SCVVNPMEHT HAATAALPAA GPVNLPTGIS
360 370 380 390 400
RVPTGYPSDL KPVTWNQHQL AHLQQMCSEA SGTPAPGLTG KHAAGRELAG
410 420 430 440 450
PGFVGKAPAY PQELCLAQSF HLKPPLEKPT PSPPVNGMAA PLAYPNGHYF
460 470 480 490 500
QPLWNNILPT PNSDSSGSQD LAMPFHGGQP TGAPLDCAAA PGAHYRAGTG
510 520 530 540 550
GGPVASQNSL MQTVDYLSGD FQQACFREQS LAMLSKAHRA PGNRAPDPTE
560
SRSLHIQHPG YR
Length:562
Mass (Da):59,652
Last modified:March 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5DCE56EBA36523C3
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B4DRX9B4DRX9_HUMAN
Protein FAM222B
FAM222B
434Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QKY8J3QKY8_HUMAN
Protein FAM222B
FAM222B
239Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QRR9J3QRR9_HUMAN
Protein FAM222B
FAM222B
179Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QLP2J3QLP2_HUMAN
Protein FAM222B
FAM222B
136Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QR32J3QR32_HUMAN
Protein FAM222B
FAM222B
43Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KSK8J3KSK8_HUMAN
Protein FAM222B
FAM222B
28Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QRM5J3QRM5_HUMAN
Protein FAM222B
FAM222B
54Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA90974 differs from that shown. Reason: Frameshift at position 433.Curated
The sequence BAB15306 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti15L → P in BAA91757 (PubMed:14702039).Curated1
Sequence conflicti261Q → R in BAA91757 (PubMed:14702039).Curated1
Sequence conflicti557Q → L in BAA91757 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_050900471L → S. Corresponds to variant dbSNP:rs2043031Ensembl.1
Natural variantiVAR_050901542G → S. Corresponds to variant dbSNP:rs36029715Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK000147 mRNA Translation: BAA90974.1 Frameshift.
AK001562 mRNA Translation: BAA91757.1
AK025980 mRNA Translation: BAB15306.1 Different initiation.
AC010761 Genomic DNA No translation available.
AC024267 Genomic DNA No translation available.
BC021228 mRNA Translation: AAH21228.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS45637.1

NCBI Reference Sequences

More...
RefSeqi
NP_001070966.1, NM_001077498.2
NP_001275560.1, NM_001288631.1
NP_001275561.1, NM_001288632.1
NP_001275562.1, NM_001288633.1
NP_001275563.1, NM_001288634.1
NP_001275564.1, NM_001288635.1
NP_001275565.1, NM_001288636.1
NP_001275566.1, NM_001288637.1
NP_001275567.1, NM_001288638.1
NP_001275568.1, NM_001288639.1
NP_001275569.1, NM_001288640.1
NP_060652.2, NM_018182.3
XP_016880320.1, XM_017024831.1
XP_016880321.1, XM_017024832.1
XP_016880322.1, XM_017024833.1
XP_016880323.1, XM_017024834.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000452648; ENSP00000413645; ENSG00000173065
ENST00000581407; ENSP00000462419; ENSG00000173065

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
55731

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55731

UCSC genome browser

More...
UCSCi
uc002hct.2 human

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK000147 mRNA Translation: BAA90974.1 Frameshift.
AK001562 mRNA Translation: BAA91757.1
AK025980 mRNA Translation: BAB15306.1 Different initiation.
AC010761 Genomic DNA No translation available.
AC024267 Genomic DNA No translation available.
BC021228 mRNA Translation: AAH21228.1
CCDSiCCDS45637.1
RefSeqiNP_001070966.1, NM_001077498.2
NP_001275560.1, NM_001288631.1
NP_001275561.1, NM_001288632.1
NP_001275562.1, NM_001288633.1
NP_001275563.1, NM_001288634.1
NP_001275564.1, NM_001288635.1
NP_001275565.1, NM_001288636.1
NP_001275566.1, NM_001288637.1
NP_001275567.1, NM_001288638.1
NP_001275568.1, NM_001288639.1
NP_001275569.1, NM_001288640.1
NP_060652.2, NM_018182.3
XP_016880320.1, XM_017024831.1
XP_016880321.1, XM_017024832.1
XP_016880322.1, XM_017024833.1
XP_016880323.1, XM_017024834.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi120850, 1 interactor
IntActiQ8WU58, 39 interactors
STRINGi9606.ENSP00000462419

PTM databases

iPTMnetiQ8WU58
PhosphoSitePlusiQ8WU58

Polymorphism and mutation databases

BioMutaiFAM222B
DMDMi74730670

Proteomic databases

EPDiQ8WU58
jPOSTiQ8WU58
PaxDbiQ8WU58
PeptideAtlasiQ8WU58
PRIDEiQ8WU58
ProteomicsDBi74633

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
55731
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000452648; ENSP00000413645; ENSG00000173065
ENST00000581407; ENSP00000462419; ENSG00000173065
GeneIDi55731
KEGGihsa:55731
UCSCiuc002hct.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55731
DisGeNETi55731

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FAM222B

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0013663
HGNCiHGNC:25563 FAM222B
HPAiHPA051840
HPA062239
neXtProtiNX_Q8WU58
OpenTargetsiENSG00000173065
PharmGKBiPA142672246

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IEMV Eukaryota
ENOG410YNEB LUCA
GeneTreeiENSGT00530000063811
HOGENOMiHOG000111757
InParanoidiQ8WU58
OMAiHLQQMCG
OrthoDBi379104at2759
PhylomeDBiQ8WU58
TreeFamiTF331508

Enzyme and pathway databases

SignaLinkiQ8WU58

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FAM222B human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
55731

Protein Ontology

More...
PROi
PR:Q8WU58

Gene expression databases

BgeeiENSG00000173065 Expressed in 235 organ(s), highest expression level in sperm
ExpressionAtlasiQ8WU58 baseline and differential
GenevisibleiQ8WU58 HS

Family and domain databases

InterProiView protein in InterPro
IPR029340 FAM222
PANTHERiPTHR16070 PTHR16070, 1 hit
PfamiView protein in Pfam
PF15258 FAM222A, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF222B_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8WU58
Secondary accession number(s): Q9H6F3, Q9NVJ4, Q9NXN6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: March 1, 2002
Last modified: May 8, 2019
This is version 106 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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