UniProtKB - Q8W4L5 (VAL1_ARATH)
Protein
B3 domain-containing transcription repressor VAL1
Gene
VAL1
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Transcriptional repressor of gene expression involved in embryonic pathways, such as LEC1, ABI3, and FUS3. Repressor of the sugar-inducible genes involved in the seed maturation program in seedlings. Plays an essential role in regulating the transition from seed maturation to seedling growth. Functionally redundant with VAL2/HSL1.3 Publications
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 295 – 396 | TF-B3PROSITE-ProRule annotationAdd BLAST | 102 | |
Zinc fingeri | 538 – 588 | CW-typePROSITE-ProRule annotationAdd BLAST | 51 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- DNA-binding transcription factor activity Source: TAIR
- zinc ion binding Source: InterPro
GO - Biological processi
- negative regulation of transcription, DNA-templated Source: TAIR
- response to abscisic acid Source: TAIR
- response to sucrose Source: TAIR
Keywordsi
Molecular function | DNA-binding, Repressor |
Biological process | Transcription, Transcription regulation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: B3 domain-containing transcription repressor VAL1Alternative name(s): Protein HIGH-LEVEL EXPRESSION OF SUGAR-INDUCIBLE 2 Protein VP1/ABI3-LIKE 1 |
Gene namesi | Name:VAL1 Synonyms:HSI2 Ordered Locus Names:At2g30470 ORF Names:T6B20.17 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT2G30470 |
TAIRi | locus:2064417, AT2G30470 |
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotation1 Publication
Mitochondrion
- mitochondrion Source: TAIR
Nucleus
- nucleus Source: TAIR
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000375117 | 1 – 790 | B3 domain-containing transcription repressor VAL1Add BLAST | 790 |
Proteomic databases
PaxDbi | Q8W4L5 |
PRIDEi | Q8W4L5 |
ProteomicsDBi | 243257 |
PTM databases
iPTMneti | Q8W4L5 |
Expressioni
Tissue specificityi
Expressed in flowers and at lower levels in roots, stems and leaves.1 Publication
Gene expression databases
ExpressionAtlasi | Q8W4L5, baseline and differential |
Genevisiblei | Q8W4L5, AT |
Interactioni
Subunit structurei
Interacts with SNL1.
1 PublicationBinary interactionsi
Q8W4L5
With | #Exp. | IntAct |
---|---|---|
PYL9 [Q84MC7] | 3 | EBI-2616403,EBI-2349513 |
Protein-protein interaction databases
BioGRIDi | 2946, 9 interactors |
IntActi | Q8W4L5, 6 interactors |
MINTi | Q8W4L5 |
STRINGi | 3702.AT2G30470.1 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q8W4L5 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 685 – 732 | Sequence analysisAdd BLAST | 48 |
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 538 – 588 | CW-typePROSITE-ProRule annotationAdd BLAST | 51 |
Keywords - Domaini
Coiled coil, Zinc-fingerPhylogenomic databases
eggNOGi | ENOG502QWC1, Eukaryota |
HOGENOMi | CLU_015907_0_0_1 |
InParanoidi | Q8W4L5 |
OMAi | TGYTHES |
OrthoDBi | 186755at2759 |
PhylomeDBi | Q8W4L5 |
Family and domain databases
CDDi | cd10017, B3_DNA, 1 hit |
Gene3Di | 2.40.330.10, 1 hit |
InterProi | View protein in InterPro IPR003340, B3_DNA-bd IPR015300, DNA-bd_pseudobarrel_sf IPR011124, Znf_CW |
Pfami | View protein in Pfam PF02362, B3, 1 hit PF07496, zf-CW, 1 hit |
SMARTi | View protein in SMART SM01019, B3, 1 hit |
SUPFAMi | SSF101936, SSF101936, 1 hit |
PROSITEi | View protein in PROSITE PS50863, B3, 1 hit PS51050, ZF_CW, 1 hit |
i Sequence
Sequence statusi: Complete.
Q8W4L5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFEVKMGSKM CMNASCGTTS TVEWKKGWPL RSGLLADLCY RCGSAYESSL
60 70 80 90 100
FCEQFHKDQS GWRECYLCSK RLHCGCIASK VTIELMDYGG VGCSTCACCH
110 120 130 140 150
QLNLNTRGEN PGVFSRLPMK TLADRQHVNG ESGGRNEGDL FSQPLVMGGD
160 170 180 190 200
KREEFMPHRG FGKLMSPEST TTGHRLDAAG EMHESSPLQP SLNMGLAVNP
210 220 230 240 250
FSPSFATEAV EGMKHISPSQ SNMVHCSASN ILQKPSRPAI STPPVASKSA
260 270 280 290 300
QARIGRPPVE GRGRGHLLPR YWPKYTDKEV QQISGNLNLN IVPLFEKTLS
310 320 330 340 350
ASDAGRIGRL VLPKACAEAY FPPISQSEGI PLKIQDVRGR EWTFQFRYWP
360 370 380 390 400
NNNSRMYVLE GVTPCIQSMM LQAGDTVTFS RVDPGGKLIM GSRKAANAGD
410 420 430 440 450
MQGCGLTNGT STEDTSSSGV TENPPSINGS SCISLIPKEL NGMPENLNSE
460 470 480 490 500
TNGGRIGDDP TRVKEKKRTR TIGAKNKRLL LHSEESMELR LTWEEAQDLL
510 520 530 540 550
RPSPSVKPTI VVIEEQEIEE YDEPPVFGKR TIVTTKPSGE QERWATCDDC
560 570 580 590 600
SKWRRLPVDA LLSFKWTCID NVWDVSRCSC SAPEESLKEL ENVLKVGREH
610 620 630 640 650
KKRRTGESQA AKSQQEPCGL DALASAAVLG DTIGEPEVAT TTRHPRHRAG
660 670 680 690 700
CSCIVCIQPP SGKGRHKPTC GCTVCSTVKR RFKTLMMRRK KKQLERDVTA
710 720 730 740 750
AEDKKKKDME LAESDKSKEE KEVNTARIDL NSDPYNKEDV EAVAVEKEES
760 770 780 790
RKRAIGQCSG VVAQDASDVL GVTELEGEGK NVREEPRVSS
Sequence cautioni
The sequence AAB63089 differs from that shown. Reason: Erroneous gene model prediction.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB206553 mRNA Translation: BAD90970.1 U93215 Genomic DNA Translation: AAB63089.1 Sequence problems. CP002685 Genomic DNA Translation: AEC08392.1 AY062492 mRNA Translation: AAL32570.1 |
PIRi | G84708 |
RefSeqi | NP_850146.1, NM_179815.3 |
Genome annotation databases
EnsemblPlantsi | AT2G30470.1; AT2G30470.1; AT2G30470 |
GeneIDi | 817597 |
Gramenei | AT2G30470.1; AT2G30470.1; AT2G30470 |
KEGGi | ath:AT2G30470 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB206553 mRNA Translation: BAD90970.1 U93215 Genomic DNA Translation: AAB63089.1 Sequence problems. CP002685 Genomic DNA Translation: AEC08392.1 AY062492 mRNA Translation: AAL32570.1 |
PIRi | G84708 |
RefSeqi | NP_850146.1, NM_179815.3 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
5YUG | X-ray | 1.57 | A/B/E/G | 1-110 | [»] | |
5YUH | X-ray | 1.80 | A | 1-110 | [»] | |
5YZY | X-ray | 2.61 | C | 273-400 | [»] | |
5YZZ | X-ray | 2.58 | C | 273-400 | [»] | |
5Z00 | X-ray | 2.59 | C/G/K/M | 273-400 | [»] | |
6FAS | X-ray | 1.90 | A/B | 287-397 | [»] | |
6J9A | X-ray | 2.92 | A | 273-403 | [»] | |
SMRi | Q8W4L5 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 2946, 9 interactors |
IntActi | Q8W4L5, 6 interactors |
MINTi | Q8W4L5 |
STRINGi | 3702.AT2G30470.1 |
PTM databases
iPTMneti | Q8W4L5 |
Proteomic databases
PaxDbi | Q8W4L5 |
PRIDEi | Q8W4L5 |
ProteomicsDBi | 243257 |
Genome annotation databases
EnsemblPlantsi | AT2G30470.1; AT2G30470.1; AT2G30470 |
GeneIDi | 817597 |
Gramenei | AT2G30470.1; AT2G30470.1; AT2G30470 |
KEGGi | ath:AT2G30470 |
Organism-specific databases
Araporti | AT2G30470 |
TAIRi | locus:2064417, AT2G30470 |
Phylogenomic databases
eggNOGi | ENOG502QWC1, Eukaryota |
HOGENOMi | CLU_015907_0_0_1 |
InParanoidi | Q8W4L5 |
OMAi | TGYTHES |
OrthoDBi | 186755at2759 |
PhylomeDBi | Q8W4L5 |
Miscellaneous databases
PROi | PR:Q8W4L5 |
Gene expression databases
ExpressionAtlasi | Q8W4L5, baseline and differential |
Genevisiblei | Q8W4L5, AT |
Family and domain databases
CDDi | cd10017, B3_DNA, 1 hit |
Gene3Di | 2.40.330.10, 1 hit |
InterProi | View protein in InterPro IPR003340, B3_DNA-bd IPR015300, DNA-bd_pseudobarrel_sf IPR011124, Znf_CW |
Pfami | View protein in Pfam PF02362, B3, 1 hit PF07496, zf-CW, 1 hit |
SMARTi | View protein in SMART SM01019, B3, 1 hit |
SUPFAMi | SSF101936, SSF101936, 1 hit |
PROSITEi | View protein in PROSITE PS50863, B3, 1 hit PS51050, ZF_CW, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | VAL1_ARATH | |
Accessioni | Q8W4L5Primary (citable) accession number: Q8W4L5 Secondary accession number(s): O04346 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 26, 2009 |
Last sequence update: | March 1, 2002 | |
Last modified: | April 7, 2021 | |
This is version 127 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - PDB cross-references
Index of Protein Data Bank (PDB) cross-references