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Entry version 111 (11 Dec 2019)
Sequence version 1 (01 Mar 2002)
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Protein

Probable chalcone--flavonone isomerase 3

Gene

CHI3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in anthocyanin biosynthesis.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • A chalcone = a flavanone. EC:5.5.1.6

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: flavonoid biosynthesis

This protein is involved in the pathway flavonoid biosynthesis, which is part of Secondary metabolite biosynthesis.
View all proteins of this organism that are known to be involved in the pathway flavonoid biosynthesis and in Secondary metabolite biosynthesis.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIsomerase
Biological processFlavonoid biosynthesis

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

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BioCyci
ARA:AT5G05270-MONOMER

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00154

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable chalcone--flavonone isomerase 3 (EC:5.5.1.6)
Short name:
Chalcone isomerase 3
Alternative name(s):
Chalcone isomerase-like 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CHI3
Synonyms:CHI-L1, CHIL
Ordered Locus Names:At5g05270
ORF Names:K18I23.7
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Arabidopsis Information Portal

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Araporti
AT5G05270

The Arabidopsis Information Resource

More...
TAIRi
locus:2153539 AT5G05270

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004220761 – 209Probable chalcone--flavonone isomerase 3Add BLAST209

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q8VZW3

PRoteomics IDEntifications database

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PRIDEi
Q8VZW3

Protein Mass spectra EXtraction

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ProMEXi
Q8VZW3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Induced by PAP1.1 Publication

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q8VZW3 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8VZW3 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
15688, 4 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT5G05270.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1209
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q8VZW3

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the chalcone isomerase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410IVHU Eukaryota
ENOG4111ZUZ LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000243947

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8VZW3

KEGG Orthology (KO)

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KOi
K01859

Identification of Orthologs from Complete Genome Data

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OMAi
MVDEIPF

Database of Orthologous Groups

More...
OrthoDBi
1381233at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8VZW3

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.890.20, 1 hit
3.50.70.10, 1 hit

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR016087 Chalcone_isomerase
IPR016088 Chalcone_isomerase_3-sand
IPR016089 Chalcone_isomerase_bundle_sf
IPR036298 Chalcone_isomerase_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02431 Chalcone, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF54626 SSF54626, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8VZW3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGTEMVMVHE VPFPPQIITS KPLSLLGQGI TDIEIHFLQV KFTAIGVYLD
60 70 80 90 100
PSDVKTHLDN WKGKTGKELA GDDDFFDALA SAEMEKVIRV VVIKEIKGAQ
110 120 130 140 150
YGVQLENTVR DRLAEEDKYE EEEETELEKV VGFFQSKYFK ANSVITYHFS
160 170 180 190 200
AKDGICEIGF ETEGKEEEKL KVENANVVGM MQRWYLSGSR GVSPSTIVSI

ADSISAVLT
Length:209
Mass (Da):23,332
Last modified:March 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i587A37BA5A91A0C7
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB09970 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AB010692 Genomic DNA Translation: BAB09970.1 Different initiation.
CP002688 Genomic DNA Translation: AED90848.1
CP002688 Genomic DNA Translation: AED90849.1
AY063786 mRNA Translation: AAL36093.1
AY096448 mRNA Translation: AAM20088.1
AY088019 mRNA Translation: AAM65565.1

NCBI Reference Sequences

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RefSeqi
NP_568154.1, NM_120609.3
NP_850770.1, NM_180439.2

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT5G05270.1; AT5G05270.1; AT5G05270
AT5G05270.2; AT5G05270.2; AT5G05270

Database of genes from NCBI RefSeq genomes

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GeneIDi
830409

Gramene; a comparative resource for plants

More...
Gramenei
AT5G05270.1; AT5G05270.1; AT5G05270
AT5G05270.2; AT5G05270.2; AT5G05270

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT5G05270

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB010692 Genomic DNA Translation: BAB09970.1 Different initiation.
CP002688 Genomic DNA Translation: AED90848.1
CP002688 Genomic DNA Translation: AED90849.1
AY063786 mRNA Translation: AAL36093.1
AY096448 mRNA Translation: AAM20088.1
AY088019 mRNA Translation: AAM65565.1
RefSeqiNP_568154.1, NM_120609.3
NP_850770.1, NM_180439.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4DOKX-ray1.70A/B5-209[»]
SMRiQ8VZW3
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi15688, 4 interactors
STRINGi3702.AT5G05270.1

Proteomic databases

PaxDbiQ8VZW3
PRIDEiQ8VZW3
ProMEXiQ8VZW3

Genome annotation databases

EnsemblPlantsiAT5G05270.1; AT5G05270.1; AT5G05270
AT5G05270.2; AT5G05270.2; AT5G05270
GeneIDi830409
GrameneiAT5G05270.1; AT5G05270.1; AT5G05270
AT5G05270.2; AT5G05270.2; AT5G05270
KEGGiath:AT5G05270

Organism-specific databases

AraportiAT5G05270
TAIRilocus:2153539 AT5G05270

Phylogenomic databases

eggNOGiENOG410IVHU Eukaryota
ENOG4111ZUZ LUCA
HOGENOMiHOG000243947
InParanoidiQ8VZW3
KOiK01859
OMAiMVDEIPF
OrthoDBi1381233at2759
PhylomeDBiQ8VZW3

Enzyme and pathway databases

UniPathwayiUPA00154
BioCyciARA:AT5G05270-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q8VZW3

Gene expression databases

ExpressionAtlasiQ8VZW3 baseline and differential
GenevisibleiQ8VZW3 AT

Family and domain databases

Gene3Di1.10.890.20, 1 hit
3.50.70.10, 1 hit
InterProiView protein in InterPro
IPR016087 Chalcone_isomerase
IPR016088 Chalcone_isomerase_3-sand
IPR016089 Chalcone_isomerase_bundle_sf
IPR036298 Chalcone_isomerase_sf
PfamiView protein in Pfam
PF02431 Chalcone, 1 hit
SUPFAMiSSF54626 SSF54626, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCFI3_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8VZW3
Secondary accession number(s): Q9FLC7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2013
Last sequence update: March 1, 2002
Last modified: December 11, 2019
This is version 111 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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