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Protein

Sialyltransferase-like protein 1

Gene

SIA1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Required for normal pollen grain germination and pollen tube growth. May not be required for pollen development and female gametophytic function.1 Publication

GO - Molecular functioni

GO - Biological processi

  • oligosaccharide metabolic process Source: GO_Central
  • pollen germination Source: TAIR
  • pollen tube growth Source: TAIR
  • protein N-linked glycosylation via asparagine Source: GO_Central
  • sialylation Source: GO_Central

Keywordsi

Molecular functionGlycosyltransferase, Transferase

Protein family/group databases

CAZyiGT29 Glycosyltransferase Family 29

Names & Taxonomyi

Protein namesi
Recommended name:
Sialyltransferase-like protein 1Curated (EC:2.4.-.-Curated)
Alternative name(s):
Protein MALE GAMETOPHYTE DEFECTIVE 21 Publication
Gene namesi
Name:SIA1Curated
Synonyms:MGP21 Publication
Ordered Locus Names:At1g08660Imported
ORF Names:F22O13.14Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G08660
TAIRilocus:2025540 AT1G08660

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 14CytoplasmicCuratedAdd BLAST14
Transmembranei15 – 35Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST21
Topological domaini36 – 474LumenalCuratedAdd BLAST439

Keywords - Cellular componenti

Golgi apparatus, Membrane

Pathology & Biotechi

Disruption phenotypei

Inhibition of pollen germination and retarded pollen tube growth.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004343091 – 474Sialyltransferase-like protein 1Add BLAST474

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi88N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi120N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi155N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi243N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ8VZJ0

Expressioni

Tissue specificityi

Highly expressed in inflorescences and siliques and at lower levels in roots, leaves and stems.1 Publication

Gene expression databases

ExpressionAtlasiQ8VZJ0 baseline and differential
GenevisibleiQ8VZJ0 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G08660.1

Structurei

3D structure databases

ProteinModelPortaliQ8VZJ0
SMRiQ8VZJ0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 29 family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2692 Eukaryota
ENOG410XT8P LUCA
HOGENOMiHOG000243861
InParanoidiQ8VZJ0
OMAiHRDFNAM
OrthoDBiEOG093607OL
PhylomeDBiQ8VZJ0

Family and domain databases

Gene3Di3.90.1480.20, 2 hits
InterProiView protein in InterPro
IPR001675 Glyco_trans_29
IPR038578 GT29-like_sf
PfamiView protein in Pfam
PF00777 Glyco_transf_29, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry describes 1 isoform i produced by alternative splicing. AlignAdd to basket
Note: A number of isoforms are produced. According to EST sequences.Curated

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8VZJ0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRSHQAGRKL PLLQLLGCVA VFSVFVFTIQ SSFFADNNRK LDLQPEDIQI
60 70 80 90 100
LSDFQSSVQQ CVANRGLGLS AHIIDHCNLI LKFPEGTNST WYNAQFKVFE
110 120 130 140 150
ALEFKYNVCE AVLLWEQYRN MTTVLTREYL DVRPDGWLDY AAMRIAQLGA
160 170 180 190 200
DKCYNRTLCE EHLNVILPAK PPFHPRQFHK CAVVGNSGDL LKTEFGEEID
210 220 230 240 250
SHDAVFRDNE APVNEKYAKY VGVKRDFRLV VRGAARNMIK ILNGSDNEVL
260 270 280 290 300
IIKSVTHRDF NEMIKRIPNP VYLFQGIVLR RGAKGTGMKS IELALSMCDI
310 320 330 340 350
VDIYGFTVDP GYTEWTRYFS TPRKGHNPLQ GRAYYQLLEC LGVIRIHSPM
360 370 380 390 400
RSERKEDWSS VPSREMISRA HTAALRLQRS QQPTSSKRDG SGQFGNCKVW
410 420 430 440 450
GDADPTKGPV SGSPDMSETR KKSNYKKWEV MPFRSLRKEA RDHYIQMKGV
460 470
SQYKMDGNKL DDLVCVRHPL KLDT
Length:474
Mass (Da):54,216
Last modified:March 1, 2002 - v1
Checksum:i13094B7D300B938E
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F4HXN8F4HXN8_ARATH
MALE GAMETOPHYTE DEFECTIVE 2
MGP2 MALE GAMETOPHYTE DEFECTIVE 2, SIA1, sialyltransferase-like 1, At1g08660, F22O13.14 MGP2 MALE GAMETOPHYTE DEFECTIVE 2, SIA1, sialyltransferase-like 1, At1g08660, F22O13.14, F22O13_14
347Annotation score:
A0A1P8AM36A0A1P8AM36_ARATH
MALE GAMETOPHYTE DEFECTIVE 2
MGP2 MALE GAMETOPHYTE DEFECTIVE 2, SIA1, sialyltransferase-like 1, At1g08660, F22O13.14 MGP2 MALE GAMETOPHYTE DEFECTIVE 2, SIA1, sialyltransferase-like 1, At1g08660, F22O13.14, F22O13_14
296Annotation score:

Sequence cautioni

The sequence AAF99778 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KJ139019 mRNA Translation: AHL38959.1
AC003981 Genomic DNA Translation: AAF99778.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE28328.1
AY064135 mRNA Translation: AAL36042.1
AY124807 mRNA Translation: AAM70516.1
PIRiT00720
RefSeqiNP_850940.1, NM_180609.4 [Q8VZJ0-1]
UniGeneiAt.27075

Genome annotation databases

EnsemblPlantsiAT1G08660.1; AT1G08660.1; AT1G08660 [Q8VZJ0-1]
GeneIDi837388
GrameneiAT1G08660.1; AT1G08660.1; AT1G08660 [Q8VZJ0-1]
KEGGiath:AT1G08660

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KJ139019 mRNA Translation: AHL38959.1
AC003981 Genomic DNA Translation: AAF99778.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE28328.1
AY064135 mRNA Translation: AAL36042.1
AY124807 mRNA Translation: AAM70516.1
PIRiT00720
RefSeqiNP_850940.1, NM_180609.4 [Q8VZJ0-1]
UniGeneiAt.27075

3D structure databases

ProteinModelPortaliQ8VZJ0
SMRiQ8VZJ0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT1G08660.1

Protein family/group databases

CAZyiGT29 Glycosyltransferase Family 29

Proteomic databases

PaxDbiQ8VZJ0

Protocols and materials databases

DNASUi837388
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G08660.1; AT1G08660.1; AT1G08660 [Q8VZJ0-1]
GeneIDi837388
GrameneiAT1G08660.1; AT1G08660.1; AT1G08660 [Q8VZJ0-1]
KEGGiath:AT1G08660

Organism-specific databases

AraportiAT1G08660
TAIRilocus:2025540 AT1G08660

Phylogenomic databases

eggNOGiKOG2692 Eukaryota
ENOG410XT8P LUCA
HOGENOMiHOG000243861
InParanoidiQ8VZJ0
OMAiHRDFNAM
OrthoDBiEOG093607OL
PhylomeDBiQ8VZJ0

Miscellaneous databases

PROiPR:Q8VZJ0

Gene expression databases

ExpressionAtlasiQ8VZJ0 baseline and differential
GenevisibleiQ8VZJ0 AT

Family and domain databases

Gene3Di3.90.1480.20, 2 hits
InterProiView protein in InterPro
IPR001675 Glyco_trans_29
IPR038578 GT29-like_sf
PfamiView protein in Pfam
PF00777 Glyco_transf_29, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSIA1_ARATH
AccessioniPrimary (citable) accession number: Q8VZJ0
Secondary accession number(s): Q9FRR9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 14, 2015
Last sequence update: March 1, 2002
Last modified: October 10, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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Main funding by: National Institutes of Health

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