Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 127 (12 Aug 2020)
Sequence version 1 (01 Mar 2002)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Aminopeptidase M1

Gene

APM1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Metallopeptidase that binds to the auxin transport inhibitor N-1-naphthylphthalamic acid (NPA). Required for embryonic and seedling development as well as cell cycle progression. Homodimerization is required to proper localization and activity. May play a negative role in the regulation of PIN auxin transport proteins.4 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide. EC:3.4.11.2

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Zn2+1 PublicationNote: Binds 1 zinc ion per subunit.1 Publication

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

    1. Vmax=59 nmol/min/mg enzyme for Tyr-aminofluoromethylcoumarin1 Publication
    2. Vmax=35 nmol/min/mg enzyme for Ala-aminofluoromethylcoumarin1 Publication
    3. Vmax=18 nmol/min/mg enzyme for Pro-aminofluoromethylcoumarin1 Publication

    Sites

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei138SubstrateBy similarity1
    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi307Zinc; catalyticPROSITE-ProRule annotation1
    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei308Proton acceptorPROSITE-ProRule annotation1
    Metal bindingi311Zinc; catalyticPROSITE-ProRule annotation1
    Metal bindingi330Zinc; catalyticPROSITE-ProRule annotation1
    <p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei392Transition state stabilizerBy similarity1

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionAminopeptidase, Hydrolase, Metalloprotease, Protease
    LigandMetal-binding, Zinc

    Protein family/group databases

    MEROPS protease database

    More...
    MEROPSi
    M01.A25

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Aminopeptidase M1 (EC:3.4.11.2)
    Alternative name(s):
    Alpha-aminoacylpeptide hydrolase
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:APM1
    Ordered Locus Names:At4g33090
    ORF Names:F4I10_20
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

    Organism-specific databases

    Arabidopsis Information Portal

    More...
    Araporti
    AT4G33090

    The Arabidopsis Information Resource

    More...
    TAIRi
    locus:2125904, AT4G33090

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

    Keywords - Cellular componenti

    Cytoplasm, Endoplasmic reticulum, Membrane, Microsome

    <p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

    <p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

    Loss-of-function mutants show irregular, uncoordinated cell divisions throughout embryogenesis, affecting the shape and number of cotyledons and the hypophysis, and is seedling lethal at 5 days after germination due to root growth arrest. Quiescent center and cell cycle markers show no signals in apm1-1 knockdown mutants, and the ground tissue specifiers SHORTROOT and SCARECROW are misexpressed or mislocalized. apm1 mutants have multiple, fused cotyledons and hypocotyls with enlarged epidermal cells with cell adhesion defects. apm1 alleles show defects in gravitropism and auxin transport.1 Publication

    Mutagenesis

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi273M → K: Abolishes function. 1 Publication1
    Mutagenesisi307H → A: Abolishes function. 1 Publication1
    Mutagenesisi729L → A: Decreases protein stability and abolishes function. 1 Publication1

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004245831 – 879Aminopeptidase M1Add BLAST879

    Proteomic databases

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    Q8VZH2

    PRoteomics IDEntifications database

    More...
    PRIDEi
    Q8VZH2

    Protein Mass spectra EXtraction

    More...
    ProMEXi
    Q8VZH2

    ProteomicsDB: a multi-organism proteome resource

    More...
    ProteomicsDBi
    244964

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    <p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

    Ubiquitous with preferential expression in 5 days-old seedlings, roots, young flowers, upper inflorescence stems, and rosette leaves.2 Publications

    <p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

    Expression starts at 3 days and peaks at 5 days. After, expression levels remain constant from 7 to 10 days. During embryogenesis, expressed first at the site of root meristem formation, then in the epidernal and ground tissue, root meristem and suspensor. In the mature embryo, expressed in the vascular primordia throughout the hypocotyl/root axis.2 Publications

    Gene expression databases

    ExpressionAtlas, Differential and Baseline Expression

    More...
    ExpressionAtlasi
    Q8VZH2, baseline and differential

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...
    Genevisiblei
    Q8VZH2, AT

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    <p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

    Homodimer.

    Interacts with N-1-naphthylphthalamic acid (NPA).

    1 Publication

    Protein-protein interaction databases

    The Biological General Repository for Interaction Datasets (BioGRID)

    More...
    BioGRIDi
    14731, 1 interactor

    Protein interaction database and analysis system

    More...
    IntActi
    Q8VZH2, 1 interactor

    STRING: functional protein association networks

    More...
    STRINGi
    3702.AT4G33090.1

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    3D structure databases

    SWISS-MODEL Repository - a database of annotated 3D protein structure models

    More...
    SMRi
    Q8VZH2

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Region

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni98 – 205Required for membrane associationAdd BLAST108
    Regioni271 – 275Substrate bindingBy similarity5

    Motif

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi728 – 729Dileucine internalization motifSequence analysis2

    <p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

    Dileucine motif seems to be involved in protein-protein interactions.

    <p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Belongs to the peptidase M1 family.Curated

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    KOG1046, Eukaryota

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    CLU_003705_0_1_1

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    Q8VZH2

    KEGG Orthology (KO)

    More...
    KOi
    K08776

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    MMEYVAI

    Database of Orthologous Groups

    More...
    OrthoDBi
    110058at2759

    Database for complete collections of gene phylogenies

    More...
    PhylomeDBi
    Q8VZH2

    Family and domain databases

    Conserved Domains Database

    More...
    CDDi
    cd09601, M1_APN-Q_like, 1 hit

    Gene3D Structural and Functional Annotation of Protein Families

    More...
    Gene3Di
    2.60.40.1730, 1 hit

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR042097, Aminopeptidase_N-like_N
    IPR024571, ERAP1-like_C_dom
    IPR034016, M1_APN-typ
    IPR001930, Peptidase_M1
    IPR014782, Peptidase_M1_dom

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF11838, ERAP1_C, 1 hit
    PF01433, Peptidase_M1, 1 hit

    Protein Motif fingerprint database; a protein domain database

    More...
    PRINTSi
    PR00756, ALADIPTASE

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF63737, SSF63737, 1 hit

    PROSITE; a protein domain and family database

    More...
    PROSITEi
    View protein in PROSITE
    PS00142, ZINC_PROTEASE, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    Q8VZH2-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MDQFKGEPRL PKFAVPKRYD LRLNPDLIAC TFTGTVAIDL DIVADTRFIV
    60 70 80 90 100
    LNAADLSVND ASVSFTPPSS SKALAAPKVV LFEEDEILVL EFGEILPHGV
    110 120 130 140 150
    GVLKLGFNGV LNDKMKGFYR STYEHNGEKK NMAVTQFEPA DARRCFPCWD
    160 170 180 190 200
    EPACKATFKI TLEVPTDLVA LSNMPIMEEK VNGNLKIVSY QESPIMSTYL
    210 220 230 240 250
    VAIVVGLFDY VEDHTSDGIK VRVYCQVGKA DQGKFALHVG AKTLDLFKEY
    260 270 280 290 300
    FAVPYPLPKM DMIAIPDFAA GAMENYGLVT YRETALLYDE QHSAASNKQR
    310 320 330 340 350
    VATVVAHELA HQWFGNLVTM EWWTHLWLNE GFATWVSYLA TDSLFPEWKI
    360 370 380 390 400
    WTQFLDESTE GLRLDGLEES HPIEVEVNHA AEIDEIFDAI SYRKGASVIR
    410 420 430 440 450
    MLQSYLGAEV FQKSLAAYIK NHAYSNAKTE DLWAALEAGS GEPVNKLMSS
    460 470 480 490 500
    WTKQKGYPVV SAKIKDGKLE LEQSRFLSSG SPGEGQWIVP VTLCCGSYEK
    510 520 530 540 550
    RKNFLLESKS GAYDLKELLG CSIADGSDKI NGTCSWIKIN VDQAGFYRVK
    560 570 580 590 600
    YDDSLAAGLR NATESQSLTS IDRYGILDDS FALTMARQQS LASLLTLCSA
    610 620 630 640 650
    YKKELDYTVL SNLIAISYKV VKIGADANQE LMSGIKHFFI GVFQFAAGKL
    660 670 680 690 700
    GWDPKQGESH LDAMLRGEVL TALAVFGHDE TLKEAVRRFD AFLADRNTPL
    710 720 730 740 750
    LPPDIRRAAY VAVMQRANKS DKSGYESLLR VYRETDLSQE KTRILGSLAS
    760 770 780 790 800
    CPDPTIVQDV LNFVLSDEVR NQDALYGLSG VSWEGREVAW KWLQEKWEYI
    810 820 830 840 850
    GNTWGSGFLI TRFISAVVSP FASFEKAKEV EEFFATRSKP SMARTLKQSI
    860 870
    ERVHINANWV ESIKKEDNLT QLVAQLSSN
    Length:879
    Mass (Da):98,179
    Last modified:March 1, 2002 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9E7E6D7E8F5AB991
    GO

    <p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

    The sequence BAD94901 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
    The sequence CAB36783 differs from that shown. Reason: Erroneous gene model prediction.Curated
    The sequence CAB80026 differs from that shown. Reason: Erroneous gene model prediction.Curated

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    AY143574 mRNA Translation: AAN41401.1
    AL035525 Genomic DNA Translation: CAB36783.1 Sequence problems.
    AL161582 Genomic DNA Translation: CAB80026.1 Sequence problems.
    CP002687 Genomic DNA Translation: AEE86172.1
    AY064961 mRNA Translation: AAL38379.1
    BT005811 mRNA Translation: AAO64746.1
    AK222071 mRNA Translation: BAD94901.1 Different initiation.
    AK227105 mRNA Translation: BAE99157.1

    Protein sequence database of the Protein Information Resource

    More...
    PIRi
    T05189

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_195035.2, NM_119463.5

    Genome annotation databases

    Ensembl plant genome annotation project

    More...
    EnsemblPlantsi
    AT4G33090.1; AT4G33090.1; AT4G33090

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    829446

    Gramene; a comparative resource for plants

    More...
    Gramenei
    AT4G33090.1; AT4G33090.1; AT4G33090

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    ath:AT4G33090

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AY143574 mRNA Translation: AAN41401.1
    AL035525 Genomic DNA Translation: CAB36783.1 Sequence problems.
    AL161582 Genomic DNA Translation: CAB80026.1 Sequence problems.
    CP002687 Genomic DNA Translation: AEE86172.1
    AY064961 mRNA Translation: AAL38379.1
    BT005811 mRNA Translation: AAO64746.1
    AK222071 mRNA Translation: BAD94901.1 Different initiation.
    AK227105 mRNA Translation: BAE99157.1
    PIRiT05189
    RefSeqiNP_195035.2, NM_119463.5

    3D structure databases

    SMRiQ8VZH2
    ModBaseiSearch...

    Protein-protein interaction databases

    BioGRIDi14731, 1 interactor
    IntActiQ8VZH2, 1 interactor
    STRINGi3702.AT4G33090.1

    Protein family/group databases

    MEROPSiM01.A25

    Proteomic databases

    PaxDbiQ8VZH2
    PRIDEiQ8VZH2
    ProMEXiQ8VZH2
    ProteomicsDBi244964

    Genome annotation databases

    EnsemblPlantsiAT4G33090.1; AT4G33090.1; AT4G33090
    GeneIDi829446
    GrameneiAT4G33090.1; AT4G33090.1; AT4G33090
    KEGGiath:AT4G33090

    Organism-specific databases

    AraportiAT4G33090
    TAIRilocus:2125904, AT4G33090

    Phylogenomic databases

    eggNOGiKOG1046, Eukaryota
    HOGENOMiCLU_003705_0_1_1
    InParanoidiQ8VZH2
    KOiK08776
    OMAiMMEYVAI
    OrthoDBi110058at2759
    PhylomeDBiQ8VZH2

    Miscellaneous databases

    Protein Ontology

    More...
    PROi
    PR:Q8VZH2

    Gene expression databases

    ExpressionAtlasiQ8VZH2, baseline and differential
    GenevisibleiQ8VZH2, AT

    Family and domain databases

    CDDicd09601, M1_APN-Q_like, 1 hit
    Gene3Di2.60.40.1730, 1 hit
    InterProiView protein in InterPro
    IPR042097, Aminopeptidase_N-like_N
    IPR024571, ERAP1-like_C_dom
    IPR034016, M1_APN-typ
    IPR001930, Peptidase_M1
    IPR014782, Peptidase_M1_dom
    PfamiView protein in Pfam
    PF11838, ERAP1_C, 1 hit
    PF01433, Peptidase_M1, 1 hit
    PRINTSiPR00756, ALADIPTASE
    SUPFAMiSSF63737, SSF63737, 1 hit
    PROSITEiView protein in PROSITE
    PS00142, ZINC_PROTEASE, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAPM1_ARATH
    <p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8VZH2
    Secondary accession number(s): Q56WG9, Q9SN00
    <p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 11, 2013
    Last sequence update: March 1, 2002
    Last modified: August 12, 2020
    This is version 127 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    <p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families
    3. Peptidase families
      Classification of peptidase families and list of entries
    UniProt is an ELIXIR core data resource
    Main funding by: National Institutes of Health

    We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

    Do not show this banner again