UniProtKB - Q8VZ59 (YUC6_ARATH)
Indole-3-pyruvate monooxygenase YUCCA6
YUC6
Functioni
Involved in auxin biosynthesis via the indole-3-pyruvic acid (IPA) pathway. Also able to convert in vitro phenyl pyruvate (PPA) to phenyl acetic acid (PAA). Required for the formation of floral organs and vascular tissues. Belongs to the set of redundant YUCCA genes probably responsible for auxin biosynthesis in shoots.
5 PublicationsCatalytic activityi
- EC:1.14.13.1682 Publications
Cofactori
Kineticsi
- KM=26 µM for NADPH2 Publications
- KM=43 µM for phenyl pyruvate2 Publications
- KM=0.274 mM for tryptamine2 Publications
- Vmax=9.46 µmol/min/mg enzyme with tryptamine as substrate2 Publications
: auxin biosynthesis Pathwayi
This protein is involved in the pathway auxin biosynthesis, which is part of Plant hormone metabolism.View all proteins of this organism that are known to be involved in the pathway auxin biosynthesis and in Plant hormone metabolism.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 36 – 41 | FADSequence analysis | 6 | |
Nucleotide bindingi | 204 – 209 | NADPSequence analysis | 6 |
GO - Molecular functioni
- flavin adenine dinucleotide binding Source: InterPro
- indole-3-pyruvate monooxygenase activity Source: UniProtKB-EC
- N,N-dimethylaniline monooxygenase activity Source: InterPro
- NADP binding Source: InterPro
GO - Biological processi
- auxin biosynthetic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Monooxygenase, Oxidoreductase |
Biological process | Auxin biosynthesis |
Ligand | FAD, Flavoprotein, NADP |
Enzyme and pathway databases
BRENDAi | 1.14.13.168, 399 |
UniPathwayi | UPA00151 |
Names & Taxonomyi
Protein namesi | Recommended name: Indole-3-pyruvate monooxygenase YUCCA6 (EC:1.14.13.168)Alternative name(s): Flavin-containing monooxygenase YUCCA6 Protein HYPERTALL1 |
Gene namesi | Name:YUC6 Synonyms:HYT1, YUCCA6 Ordered Locus Names:At5g25620 ORF Names:T14C9.160 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT5G25620 |
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm 1 Publication
Other locations
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPathology & Biotechi
Disruption phenotypei
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000400073 | 1 – 417 | Indole-3-pyruvate monooxygenase YUCCA6Add BLAST | 417 |
Proteomic databases
PaxDbi | Q8VZ59 |
PRIDEi | Q8VZ59 |
Expressioni
Tissue specificityi
Inductioni
Gene expression databases
ExpressionAtlasi | Q8VZ59, baseline and differential |
Genevisiblei | Q8VZ59, AT |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG1399, Eukaryota |
InParanoidi | Q8VZ59 |
OMAi | WRRHYDR |
PhylomeDBi | Q8VZ59 |
Family and domain databases
Gene3Di | 3.50.50.60, 1 hit |
InterProi | View protein in InterPro IPR036188, FAD/NAD-bd_sf IPR020946, Flavin_mOase-like IPR036291, NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF00743, FMO-like, 1 hit |
SUPFAMi | SSF51735, SSF51735, 1 hit SSF51905, SSF51905, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry describes 1 produced by isoform ialternative splicing. AlignAdd to basketThis entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MDFCWKREME GKLAHDHRGM TSPRRICVVT GPVIVGAGPS GLATAACLKE
60 70 80 90 100
RGITSVLLER SNCIASLWQL KTYDRLHLHL PKQFCELPII PFPGDFPTYP
110 120 130 140 150
TKQQFIEYLE DYARRFDIKP EFNQTVESAA FDENLGMWRV TSVGEEGTTE
160 170 180 190 200
YVCRWLVAAT GENAEPVVPR FEGMDKFAAA GVVKHTCHYK TGGDFAGKRV
210 220 230 240 250
LVVGCGNSGM EVCLDLCNFG AQPSLVVRDA VHVLPREMLG TSTFGLSMFL
260 270 280 290 300
LKWLPIRLVD RFLLVVSRFI LGDTTLLGLN RPRLGPLELK NISGKTPVLD
310 320 330 340 350
VGTLAKIKTG DIKVCSGIRR LKRHEVEFDN GKTERFDAII LATGYKSNVP
360 370 380 390 400
SWLKENKMFS KKDGFPIQEF PEGWRGECGL YAVGFTKRGI SGASMDAKRI
410
AEDIHKCWKQ DEQVKKI
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketF4JY69 | F4JY69_ARATH | Flavin-containing monooxygenase | YUC6 AtYUC6, YUCCA6, At5g25620, T14C9.160, T14C9_160 | 434 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC006601 Genomic DNA No translation available. CP002688 Genomic DNA Translation: AED93473.1 AY065229 mRNA Translation: AAL38705.1 AY113851 mRNA Translation: AAM44899.1 |
RefSeqi | NP_197944.2, NM_122473.3 [Q8VZ59-1] |
Genome annotation databases
EnsemblPlantsi | AT5G25620.1; AT5G25620.1; AT5G25620 [Q8VZ59-1] |
GeneIDi | 832638 |
Gramenei | AT5G25620.1; AT5G25620.1; AT5G25620 [Q8VZ59-1] |
KEGGi | ath:AT5G25620 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC006601 Genomic DNA No translation available. CP002688 Genomic DNA Translation: AED93473.1 AY065229 mRNA Translation: AAL38705.1 AY113851 mRNA Translation: AAM44899.1 |
RefSeqi | NP_197944.2, NM_122473.3 [Q8VZ59-1] |
3D structure databases
SMRi | Q8VZ59 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 3702.AT5G25620.2 |
Proteomic databases
PaxDbi | Q8VZ59 |
PRIDEi | Q8VZ59 |
Genome annotation databases
EnsemblPlantsi | AT5G25620.1; AT5G25620.1; AT5G25620 [Q8VZ59-1] |
GeneIDi | 832638 |
Gramenei | AT5G25620.1; AT5G25620.1; AT5G25620 [Q8VZ59-1] |
KEGGi | ath:AT5G25620 |
Organism-specific databases
Araporti | AT5G25620 |
Phylogenomic databases
eggNOGi | KOG1399, Eukaryota |
InParanoidi | Q8VZ59 |
OMAi | WRRHYDR |
PhylomeDBi | Q8VZ59 |
Enzyme and pathway databases
UniPathwayi | UPA00151 |
BRENDAi | 1.14.13.168, 399 |
Miscellaneous databases
PROi | PR:Q8VZ59 |
Gene expression databases
ExpressionAtlasi | Q8VZ59, baseline and differential |
Genevisiblei | Q8VZ59, AT |
Family and domain databases
Gene3Di | 3.50.50.60, 1 hit |
InterProi | View protein in InterPro IPR036188, FAD/NAD-bd_sf IPR020946, Flavin_mOase-like IPR036291, NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF00743, FMO-like, 1 hit |
SUPFAMi | SSF51735, SSF51735, 1 hit SSF51905, SSF51905, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | YUC6_ARATH | |
Accessioni | Q8VZ59Primary (citable) accession number: Q8VZ59 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 2, 2010 |
Last sequence update: | March 1, 2002 | |
Last modified: | February 23, 2022 | |
This is version 138 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families