Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 133 (12 Aug 2020)
Sequence version 1 (01 Mar 2002)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Nuclear poly(A) polymerase 4

Gene

PAPS4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Essential protein (PubMed:19956626). Polymerase that creates the 3'-poly(A) tail of mRNA's (PubMed:15297145). Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus (By similarity).By similarity2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium ions. Also active with manganese.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi114Magnesium 1; catalyticBy similarity1
Metal bindingi114Magnesium 2; catalyticBy similarity1
Metal bindingi116Magnesium 1; catalyticBy similarity1
Metal bindingi116Magnesium 2; catalyticBy similarity1
Metal bindingi169Magnesium 2; catalyticBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei169ATPBy similarity1
Binding sitei230ATPBy similarity1
Binding sitei239ATPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi101 – 103ATPBy similarity3
Nucleotide bindingi113 – 116ATPBy similarity4
Nucleotide bindingi114 – 116ATPBy similarity3
Nucleotide bindingi248 – 249ATPBy similarity2

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionNucleotidyltransferase, Transferase
Biological processmRNA processing
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.7.7.19, 399

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nuclear poly(A) polymerase 41 Publication (EC:2.7.7.191 Publication)
Short name:
AtPAP(IV)1 Publication
Short name:
PAP(IV)Curated
Short name:
Poly(A) polymerase IVCurated
Short name:
nPAP1 Publication
Alternative name(s):
Polynucleotide adenylyltransferase 4Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PAPS41 Publication
Synonyms:NPAP1 Publication
Ordered Locus Names:At4g32850Imported
ORF Names:T16I18.60Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT4G32850

The Arabidopsis Information Resource

More...
TAIRi
locus:2134113, AT4G32850

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Lethal.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004313481 – 741Nuclear poly(A) polymerase 4Add BLAST741

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8VYW1

PRoteomics IDEntifications database

More...
PRIDEi
Q8VYW1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
236323 [Q8VYW1-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8VYW1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Mostly expressed in flowers (very active in pollen, sepals, styles, and stigmas), cotyledons and hypocotyls, and, to a lower extent, in roots (confined to the vascular tissue in the radicle) and leaves (in the vascular tissue and leaf petioles). Barely detected in stems (PubMed:15297145, PubMed:19956626). Active in the primary and secondary root systems (PubMed:19956626).2 Publications

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8VYW1, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8VYW1, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer (By similarity).

Forms a complex with cleavage and polyadenylation specificity factor (CPSF) subunits CFIS2, FIPS3, PAPS1, PABN1, PABN2, PABN3 and FIPS5 (PubMed:16282318, PubMed:18479511).

By similarity2 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei160Interaction with RNABy similarity1
Sitei330Interaction with RNABy similarity1
Sitei401Interaction with RNABy similarity1
Sitei406Interaction with RNABy similarity1
Sitei598Interaction with RNABy similarity1

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
14706, 9 interactors

Protein interaction database and analysis system

More...
IntActi
Q8VYW1, 7 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT4G32850.8

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8VYW1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi485 – 492Nuclear localization signalPROSITE-ProRule annotation8

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the poly(A) polymerase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2245, Eukaryota

KEGG Orthology (KO)

More...
KOi
K14376

Identification of Orthologs from Complete Genome Data

More...
OMAi
QNRDYEE

Database of Orthologous Groups

More...
OrthoDBi
326577at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8VYW1

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.460.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR043519, NT_sf
IPR011068, NuclTrfase_I-like_C
IPR007012, PolA_pol_cen_dom
IPR007010, PolA_pol_RNA-bd_dom
IPR014492, PolyA_polymerase
IPR002934, Polymerase_NTP_transf_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01909, NTP_transf_2, 1 hit
PF04928, PAP_central, 1 hit
PF04926, PAP_RNA-bind, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF018425, PolyA_polymerase, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF55003, SSF55003, 1 hit
SSF81301, SSF81301, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (8)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 8 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q8VYW1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MMVGTQNLGG SLPPLNSPKS YGITKPLSLA GPSSADIKRN VELEKYLVDE
60 70 80 90 100
GLYESKDDTM RREEVLGRID QIVKHWVKQL TQQRGYTDQM VEDANAVIFT
110 120 130 140 150
FGSYRLGVHG PGADIDTLCV GPSYVNREED FFIILHDILA EMEEVTELHP
160 170 180 190 200
VPDAHVPVMK FKFQGIPIDL LYASISLLVV PQDLDISSSS VLCEVDEPTV
210 220 230 240 250
RSLNGCRVAD QILKLVPNFE HFRTTLRCLK YWAKKRGVYS NVTGFLGGVN
260 270 280 290 300
WALLVARVCQ LYPNAIPSML VSRFFRVYTQ WRWPNPVMLC AIEEDELGFP
310 320 330 340 350
VWDRRKNHRD RYHLMPIITP AYPCMNSSYN VSQSTLRVMT EQFQFGNNIL
360 370 380 390 400
QEIELNKQHW SSLFEQYMFF EAYKNYLQVD IVAADAEDLL AWKGWVESRF
410 420 430 440 450
RQLTLKIERD TNGMLMCHPQ PNEYVDTARQ FLHCAFFMGL QRAEGVGGQE
460 470 480 490 500
CQQFDIRGTV DEFRQEVNMY MFWKPGMDVF VSHVRRRQLP PFVFPNGYRR
510 520 530 540 550
PRQSRHQNLP GGKSGEDGSV SHSGSVVERH AKRKNDSEMM DVRPEKPEKR
560 570 580 590 600
ASLSPQSLDI VSPENSAITT GWTPPVCNLR RPPSEEIEAD NLNTECTELT
610 620 630 640 650
DLARNECNSG SEQVLEVDSM AVVQECSDPA EPLGKCVTPD SVDVVACVSG
660 670 680 690 700
QEENLDRNLR SVSISGTDSP LLPSRSCGQN RDYEGFGFPA ANSDPMGKKN
710 720 730 740
LYSQSGMSED LQSNSLVSGM EKSEDRARSE SFQKSQIRLL T
Length:741
Mass (Da):83,943
Last modified:March 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBCA233700431BB6D
GO
Isoform 2 (identifier: Q8VYW1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     739-741: LLT → HVCYAKS

Show »
Length:745
Mass (Da):84,405
Checksum:i735F77CB63A7D5B0
GO
Isoform 3 (identifier: Q8VYW1-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     740-741: LT → SLKSTV

Note: Incomplete sequence.1 Publication
Show »
Length:745
Mass (Da):84,344
Checksum:i743DFFB30A30A370
GO
Isoform 4 (identifier: Q8VYW1-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     728-741: RSESFQKSQIRLLT → STSRLSLKSTV

Note: Incomplete sequence.1 Publication
Show »
Length:738
Mass (Da):83,428
Checksum:i301D1888E989C28B
GO
Isoform 5 (identifier: Q8VYW1-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     713-730: SNSLVSGMEKSEDRARSE → VIKLPHSSYHKISSVENI
     731-741: Missing.

Show »
Length:730
Mass (Da):82,710
Checksum:iD575F77A85673584
GO
Isoform 6 (identifier: Q8VYW1-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     729-741: SESFQKSQIRLLT → LSLKSTV

Show »
Length:735
Mass (Da):83,153
Checksum:i5C0F09C68852C41B
GO
Isoform 7 (identifier: Q8VYW1-7) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     713-716: SNSL → CQET
     717-741: Missing.

Show »
Length:716
Mass (Da):81,138
Checksum:i1F277FBEFC4F786D
GO
Isoform 8 (identifier: Q8VYW1-8) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     739-741: LLT → HAIDVKKTGDFNSNCCVGQTTESRSFW

Show »
Length:765
Mass (Da):86,629
Checksum:iCCCAF39132F2A101
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAB80002 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_057246713 – 730SNSLV…RARSE → VIKLPHSSYHKISSVENI in isoform 5. Add BLAST18
Alternative sequenceiVSP_057247713 – 716SNSL → CQET in isoform 7. 4
Alternative sequenceiVSP_057248717 – 741Missing in isoform 7. Add BLAST25
Alternative sequenceiVSP_057249728 – 741RSESF…IRLLT → STSRLSLKSTV in isoform 4. Add BLAST14
Alternative sequenceiVSP_057250729 – 741SESFQ…IRLLT → LSLKSTV in isoform 6. Add BLAST13
Alternative sequenceiVSP_057251731 – 741Missing in isoform 5. Add BLAST11
Alternative sequenceiVSP_057252739 – 741LLT → HVCYAKS in isoform 2. 3
Alternative sequenceiVSP_057253739 – 741LLT → HAIDVKKTGDFNSNCCVGQT TESRSFW in isoform 8. 3
Alternative sequenceiVSP_057254740 – 741LT → SLKSTV in isoform 3. 2

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL161582 Genomic DNA Translation: CAB80002.1 Different initiation.
CP002687 Genomic DNA Translation: AEE86126.1
CP002687 Genomic DNA Translation: AEE86127.1
CP002687 Genomic DNA Translation: AEE86128.1
CP002687 Genomic DNA Translation: AEE86129.1
CP002687 Genomic DNA Translation: AEE86130.1
CP002687 Genomic DNA Translation: AEE86131.1
CP002687 Genomic DNA Translation: AEE86132.1
CP002687 Genomic DNA Translation: AEE86133.1
CP002687 Genomic DNA Translation: AEE86134.1
CP002687 Genomic DNA Translation: AEE86135.1
CP002687 Genomic DNA Translation: ANM67865.1
CP002687 Genomic DNA Translation: ANM67866.1
CP002687 Genomic DNA Translation: ANM67867.1
CP002687 Genomic DNA Translation: ANM67868.1
CP002687 Genomic DNA Translation: ANM67869.1
CP002687 Genomic DNA Translation: ANM67870.1
CP002687 Genomic DNA Translation: ANM67871.1
AY069880 mRNA Translation: AAL47435.1
BT000485 mRNA Translation: AAN18054.1
AK316738 mRNA Translation: BAH19461.1
AK318704 mRNA Translation: BAH56819.1
AY323908 mRNA Translation: AAP86216.1
AK230297 mRNA Translation: BAF02098.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T10692

NCBI Reference Sequences

More...
RefSeqi
NP_001031778.1, NM_001036701.1 [Q8VYW1-7]
NP_001031779.1, NM_001036702.1 [Q8VYW1-8]
NP_001119102.1, NM_001125630.1 [Q8VYW1-3]
NP_001119103.1, NM_001125631.2 [Q8VYW1-2]
NP_001329663.1, NM_001342181.1 [Q8VYW1-5]
NP_001329664.1, NM_001342180.1 [Q8VYW1-5]
NP_001329665.1, NM_001342179.1 [Q8VYW1-5]
NP_001329666.1, NM_001342185.1 [Q8VYW1-5]
NP_001329667.1, NM_001342184.1 [Q8VYW1-5]
NP_001329668.1, NM_001342183.1 [Q8VYW1-5]
NP_001329669.1, NM_001342182.1 [Q8VYW1-5]
NP_195011.4, NM_119438.4 [Q8VYW1-6]
NP_849561.1, NM_179230.2 [Q8VYW1-1]
NP_849562.2, NM_179231.2 [Q8VYW1-4]
NP_974668.1, NM_202939.3 [Q8VYW1-5]
NP_974669.1, NM_202940.3 [Q8VYW1-3]
NP_974670.2, NM_202941.3 [Q8VYW1-4]

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT4G32850.1; AT4G32850.1; AT4G32850 [Q8VYW1-1]
AT4G32850.10; AT4G32850.10; AT4G32850 [Q8VYW1-2]
AT4G32850.11; AT4G32850.11; AT4G32850 [Q8VYW1-5]
AT4G32850.12; AT4G32850.12; AT4G32850 [Q8VYW1-5]
AT4G32850.13; AT4G32850.13; AT4G32850 [Q8VYW1-5]
AT4G32850.14; AT4G32850.14; AT4G32850 [Q8VYW1-5]
AT4G32850.15; AT4G32850.15; AT4G32850 [Q8VYW1-5]
AT4G32850.16; AT4G32850.16; AT4G32850 [Q8VYW1-5]
AT4G32850.17; AT4G32850.17; AT4G32850 [Q8VYW1-5]
AT4G32850.2; AT4G32850.2; AT4G32850 [Q8VYW1-4]
AT4G32850.3; AT4G32850.3; AT4G32850 [Q8VYW1-6]
AT4G32850.4; AT4G32850.4; AT4G32850 [Q8VYW1-5]
AT4G32850.5; AT4G32850.5; AT4G32850 [Q8VYW1-3]
AT4G32850.6; AT4G32850.6; AT4G32850 [Q8VYW1-4]
AT4G32850.7; AT4G32850.7; AT4G32850 [Q8VYW1-7]
AT4G32850.8; AT4G32850.8; AT4G32850 [Q8VYW1-8]
AT4G32850.9; AT4G32850.9; AT4G32850 [Q8VYW1-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
829421

Gramene; a comparative resource for plants

More...
Gramenei
AT4G32850.1; AT4G32850.1; AT4G32850 [Q8VYW1-1]
AT4G32850.10; AT4G32850.10; AT4G32850 [Q8VYW1-2]
AT4G32850.11; AT4G32850.11; AT4G32850 [Q8VYW1-5]
AT4G32850.12; AT4G32850.12; AT4G32850 [Q8VYW1-5]
AT4G32850.13; AT4G32850.13; AT4G32850 [Q8VYW1-5]
AT4G32850.14; AT4G32850.14; AT4G32850 [Q8VYW1-5]
AT4G32850.15; AT4G32850.15; AT4G32850 [Q8VYW1-5]
AT4G32850.16; AT4G32850.16; AT4G32850 [Q8VYW1-5]
AT4G32850.17; AT4G32850.17; AT4G32850 [Q8VYW1-5]
AT4G32850.2; AT4G32850.2; AT4G32850 [Q8VYW1-4]
AT4G32850.3; AT4G32850.3; AT4G32850 [Q8VYW1-6]
AT4G32850.4; AT4G32850.4; AT4G32850 [Q8VYW1-5]
AT4G32850.5; AT4G32850.5; AT4G32850 [Q8VYW1-3]
AT4G32850.6; AT4G32850.6; AT4G32850 [Q8VYW1-4]
AT4G32850.7; AT4G32850.7; AT4G32850 [Q8VYW1-7]
AT4G32850.8; AT4G32850.8; AT4G32850 [Q8VYW1-8]
AT4G32850.9; AT4G32850.9; AT4G32850 [Q8VYW1-3]

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT4G32850

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL161582 Genomic DNA Translation: CAB80002.1 Different initiation.
CP002687 Genomic DNA Translation: AEE86126.1
CP002687 Genomic DNA Translation: AEE86127.1
CP002687 Genomic DNA Translation: AEE86128.1
CP002687 Genomic DNA Translation: AEE86129.1
CP002687 Genomic DNA Translation: AEE86130.1
CP002687 Genomic DNA Translation: AEE86131.1
CP002687 Genomic DNA Translation: AEE86132.1
CP002687 Genomic DNA Translation: AEE86133.1
CP002687 Genomic DNA Translation: AEE86134.1
CP002687 Genomic DNA Translation: AEE86135.1
CP002687 Genomic DNA Translation: ANM67865.1
CP002687 Genomic DNA Translation: ANM67866.1
CP002687 Genomic DNA Translation: ANM67867.1
CP002687 Genomic DNA Translation: ANM67868.1
CP002687 Genomic DNA Translation: ANM67869.1
CP002687 Genomic DNA Translation: ANM67870.1
CP002687 Genomic DNA Translation: ANM67871.1
AY069880 mRNA Translation: AAL47435.1
BT000485 mRNA Translation: AAN18054.1
AK316738 mRNA Translation: BAH19461.1
AK318704 mRNA Translation: BAH56819.1
AY323908 mRNA Translation: AAP86216.1
AK230297 mRNA Translation: BAF02098.1
PIRiT10692
RefSeqiNP_001031778.1, NM_001036701.1 [Q8VYW1-7]
NP_001031779.1, NM_001036702.1 [Q8VYW1-8]
NP_001119102.1, NM_001125630.1 [Q8VYW1-3]
NP_001119103.1, NM_001125631.2 [Q8VYW1-2]
NP_001329663.1, NM_001342181.1 [Q8VYW1-5]
NP_001329664.1, NM_001342180.1 [Q8VYW1-5]
NP_001329665.1, NM_001342179.1 [Q8VYW1-5]
NP_001329666.1, NM_001342185.1 [Q8VYW1-5]
NP_001329667.1, NM_001342184.1 [Q8VYW1-5]
NP_001329668.1, NM_001342183.1 [Q8VYW1-5]
NP_001329669.1, NM_001342182.1 [Q8VYW1-5]
NP_195011.4, NM_119438.4 [Q8VYW1-6]
NP_849561.1, NM_179230.2 [Q8VYW1-1]
NP_849562.2, NM_179231.2 [Q8VYW1-4]
NP_974668.1, NM_202939.3 [Q8VYW1-5]
NP_974669.1, NM_202940.3 [Q8VYW1-3]
NP_974670.2, NM_202941.3 [Q8VYW1-4]

3D structure databases

SMRiQ8VYW1
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi14706, 9 interactors
IntActiQ8VYW1, 7 interactors
STRINGi3702.AT4G32850.8

PTM databases

iPTMnetiQ8VYW1

Proteomic databases

PaxDbiQ8VYW1
PRIDEiQ8VYW1
ProteomicsDBi236323 [Q8VYW1-1]

Genome annotation databases

EnsemblPlantsiAT4G32850.1; AT4G32850.1; AT4G32850 [Q8VYW1-1]
AT4G32850.10; AT4G32850.10; AT4G32850 [Q8VYW1-2]
AT4G32850.11; AT4G32850.11; AT4G32850 [Q8VYW1-5]
AT4G32850.12; AT4G32850.12; AT4G32850 [Q8VYW1-5]
AT4G32850.13; AT4G32850.13; AT4G32850 [Q8VYW1-5]
AT4G32850.14; AT4G32850.14; AT4G32850 [Q8VYW1-5]
AT4G32850.15; AT4G32850.15; AT4G32850 [Q8VYW1-5]
AT4G32850.16; AT4G32850.16; AT4G32850 [Q8VYW1-5]
AT4G32850.17; AT4G32850.17; AT4G32850 [Q8VYW1-5]
AT4G32850.2; AT4G32850.2; AT4G32850 [Q8VYW1-4]
AT4G32850.3; AT4G32850.3; AT4G32850 [Q8VYW1-6]
AT4G32850.4; AT4G32850.4; AT4G32850 [Q8VYW1-5]
AT4G32850.5; AT4G32850.5; AT4G32850 [Q8VYW1-3]
AT4G32850.6; AT4G32850.6; AT4G32850 [Q8VYW1-4]
AT4G32850.7; AT4G32850.7; AT4G32850 [Q8VYW1-7]
AT4G32850.8; AT4G32850.8; AT4G32850 [Q8VYW1-8]
AT4G32850.9; AT4G32850.9; AT4G32850 [Q8VYW1-3]
GeneIDi829421
GrameneiAT4G32850.1; AT4G32850.1; AT4G32850 [Q8VYW1-1]
AT4G32850.10; AT4G32850.10; AT4G32850 [Q8VYW1-2]
AT4G32850.11; AT4G32850.11; AT4G32850 [Q8VYW1-5]
AT4G32850.12; AT4G32850.12; AT4G32850 [Q8VYW1-5]
AT4G32850.13; AT4G32850.13; AT4G32850 [Q8VYW1-5]
AT4G32850.14; AT4G32850.14; AT4G32850 [Q8VYW1-5]
AT4G32850.15; AT4G32850.15; AT4G32850 [Q8VYW1-5]
AT4G32850.16; AT4G32850.16; AT4G32850 [Q8VYW1-5]
AT4G32850.17; AT4G32850.17; AT4G32850 [Q8VYW1-5]
AT4G32850.2; AT4G32850.2; AT4G32850 [Q8VYW1-4]
AT4G32850.3; AT4G32850.3; AT4G32850 [Q8VYW1-6]
AT4G32850.4; AT4G32850.4; AT4G32850 [Q8VYW1-5]
AT4G32850.5; AT4G32850.5; AT4G32850 [Q8VYW1-3]
AT4G32850.6; AT4G32850.6; AT4G32850 [Q8VYW1-4]
AT4G32850.7; AT4G32850.7; AT4G32850 [Q8VYW1-7]
AT4G32850.8; AT4G32850.8; AT4G32850 [Q8VYW1-8]
AT4G32850.9; AT4G32850.9; AT4G32850 [Q8VYW1-3]
KEGGiath:AT4G32850

Organism-specific databases

AraportiAT4G32850
TAIRilocus:2134113, AT4G32850

Phylogenomic databases

eggNOGiKOG2245, Eukaryota
KOiK14376
OMAiQNRDYEE
OrthoDBi326577at2759
PhylomeDBiQ8VYW1

Enzyme and pathway databases

BRENDAi2.7.7.19, 399

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q8VYW1

Gene expression databases

ExpressionAtlasiQ8VYW1, baseline and differential
GenevisibleiQ8VYW1, AT

Family and domain databases

Gene3Di3.30.460.10, 1 hit
InterProiView protein in InterPro
IPR043519, NT_sf
IPR011068, NuclTrfase_I-like_C
IPR007012, PolA_pol_cen_dom
IPR007010, PolA_pol_RNA-bd_dom
IPR014492, PolyA_polymerase
IPR002934, Polymerase_NTP_transf_dom
PfamiView protein in Pfam
PF01909, NTP_transf_2, 1 hit
PF04928, PAP_central, 1 hit
PF04926, PAP_RNA-bind, 1 hit
PIRSFiPIRSF018425, PolyA_polymerase, 1 hit
SUPFAMiSSF55003, SSF55003, 1 hit
SSF81301, SSF81301, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPAPS4_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8VYW1
Secondary accession number(s): B3H654
, B9DFE4, F4JV63, F4JV67, F4JV69, F4JV71, F4JV72, Q0WLA9, Q7XJ91, Q9M075
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 26, 2014
Last sequence update: March 1, 2002
Last modified: August 12, 2020
This is version 133 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again