UniProtKB - Q8VYJ7 (CLPB4_ARATH)
Protein
Chaperone protein ClpB4, mitochondrial
Gene
CLPB4
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Molecular chaperone that does not seem to be involved in heat stress response or tolerance.1 Publication
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 287 – 294 | ATPSequence analysis | 8 | |
Nucleotide bindingi | 690 – 697 | ATPSequence analysis | 8 |
GO - Molecular functioni
- ATPase activity Source: GO_Central
- ATP binding Source: UniProtKB-KW
GO - Biological processi
- cellular response to heat Source: GO_Central
- protein refolding Source: InterPro
Keywordsi
Molecular function | Chaperone |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Chaperone protein ClpB4, mitochondrialAlternative name(s): ATP-dependent Clp protease ATP-binding subunit ClpB homolog 4 Casein lytic proteinase B4 |
Gene namesi | Name:CLPB4 Synonyms:CLPB-M, HSP98.7 Ordered Locus Names:At2g25140 ORF Names:F13D4.100 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT2G25140 |
TAIRi | locus:2040159, AT2G25140 |
Subcellular locationi
Mitochondrion
- Mitochondrion 1 Publication
Chloroplast
- chloroplast Source: TAIR
- chloroplast envelope Source: TAIR
- chloroplast stroma Source: TAIR
Mitochondrion
- mitochondrion Source: TAIR
Other locations
- cytoplasm Source: GO_Central
Keywords - Cellular componenti
MitochondrionPathology & Biotechi
Disruption phenotypei
No visible phenotype under normal growth conditions.1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 39 | MitochondrionSequence analysisAdd BLAST | 39 | |
ChainiPRO_0000412574 | 40 – 964 | Chaperone protein ClpB4, mitochondrialAdd BLAST | 925 |
Proteomic databases
PaxDbi | Q8VYJ7 |
PRIDEi | Q8VYJ7 |
ProteomicsDBi | 246654 |
PTM databases
iPTMneti | Q8VYJ7 |
SwissPalmi | Q8VYJ7 |
Expressioni
Inductioni
By heat stress.2 Publications
Gene expression databases
ExpressionAtlasi | Q8VYJ7, baseline and differential |
Genevisiblei | Q8VYJ7, AT |
Interactioni
Protein-protein interaction databases
BioGRIDi | 2404, 6 interactors |
IntActi | Q8VYJ7, 1 interactor |
STRINGi | 3702.AT2G25140.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 83 – 227 | Clp RPROSITE-ProRule annotationAdd BLAST | 145 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 88 – 153 | Repeat 1PROSITE-ProRule annotationAdd BLAST | 66 | |
Regioni | 164 – 227 | Repeat 2PROSITE-ProRule annotationAdd BLAST | 64 | |
Regioni | 242 – 490 | IBy similarityAdd BLAST | 249 | |
Regioni | 616 – 807 | IIBy similarityAdd BLAST | 192 |
Sequence similaritiesi
Belongs to the ClpA/ClpB family.Curated
Keywords - Domaini
Repeat, Transit peptidePhylogenomic databases
eggNOGi | KOG1051, Eukaryota |
HOGENOMi | CLU_005070_4_2_1 |
InParanoidi | Q8VYJ7 |
OMAi | YEVFHGV |
OrthoDBi | 611758at2759 |
PhylomeDBi | Q8VYJ7 |
Family and domain databases
Gene3Di | 1.10.1780.10, 1 hit |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003959, ATPase_AAA_core IPR017730, Chaperonin_ClpB IPR019489, Clp_ATPase_C IPR036628, Clp_N_dom_sf IPR004176, Clp_R_dom IPR001270, ClpA/B IPR018368, ClpA/B_CS1 IPR028299, ClpA/B_CS2 IPR041546, ClpA/ClpB_AAA_lid IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00004, AAA, 1 hit PF07724, AAA_2, 1 hit PF17871, AAA_lid_9, 1 hit PF02861, Clp_N, 2 hits PF10431, ClpB_D2-small, 1 hit |
PRINTSi | PR00300, CLPPROTEASEA |
SMARTi | View protein in SMART SM00382, AAA, 2 hits SM01086, ClpB_D2-small, 1 hit |
SUPFAMi | SSF52540, SSF52540, 2 hits SSF81923, SSF81923, 1 hit |
TIGRFAMsi | TIGR03346, chaperone_ClpB, 1 hit |
PROSITEi | View protein in PROSITE PS51903, CLP_R, 1 hit PS00870, CLPAB_1, 1 hit PS00871, CLPAB_2, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q8VYJ7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MALRRLSKSV SSAIKAQYTL SRPSPLLRSR SLSSSPHYTS IGRPTNSFIG
60 70 80 90 100
KINNSSITHA TTTHGQLFPL SSPRRFCTTT AQVNQNEFTE MAWEGLINAF
110 120 130 140 150
DAARESKQQI VESEHLMKAL LEQKDGMARK IFTKAGIDNS SVLQATDLFI
160 170 180 190 200
SKQPTVSDAS GQRLGSSLSV ILENAKRHKK DMLDSYVSVE HFLLAYYSDT
210 220 230 240 250
RFGQEFFRDM KLDIQVLKDA IKDVRGDQRV TDRNPESKYQ ALEKYGNDLT
260 270 280 290 300
EMARRGKLDP VIGRDDEIRR CIQILCRRTK NNPVIIGEPG VGKTAIAEGL
310 320 330 340 350
AQRIVRGDVP EPLMNRKLIS LDMGSLLAGA KFRGDFEERL KAVMKEVSAS
360 370 380 390 400
NGQTILFIDE IHTVVGAGAM DGAMDASNLL KPMLGRGELR CIGATTLTEY
410 420 430 440 450
RKYIEKDPAL ERRFQQVLCV QPSVEDTISI LRGLRERYEL HHGVTISDSA
460 470 480 490 500
LVSAAVLADR YITERFLPDK AIDLVDEAGA KLKMEITSKP TELDGIDRAV
510 520 530 540 550
IKLEMEKLSL KNDTDKASKE RLQKIENDLS TLKQKQKELN VQWEKEKSLM
560 570 580 590 600
TKIRSFKEEI DRVNLEIESA EREYDLNRAA ELKYGTLLSL QRQLEEAEKN
610 620 630 640 650
LTNFRQFGQS LLREVVTDLD IAEIVSKWTG IPLSNLQQSE REKLVMLEEV
660 670 680 690 700
LHHRVIGQDM AVKSVADAIR RSRAGLSDPN RPIASFMFMG PTGVGKTELA
710 720 730 740 750
KALAGYLFNT ENAIVRVDMS EYMEKHSVSR LVGAPPGYVG YEEGGQLTEV
760 770 780 790 800
VRRRPYSVVL FDEIEKAHPD VFNILLQLLD DGRITDSQGR TVSFKNCVVI
810 820 830 840 850
MTSNIGSHHI LETLRNNEDS KEAVYEIMKR QVVELARQNF RPEFMNRIDE
860 870 880 890 900
YIVFQPLDSN EISKIVELQM RRVKNSLEQK KIKLQYTKEA VDLLAQLGFD
910 920 930 940 950
PNYGARPVKR VIQQMVENEI AVGILKGDFA EEDTVLVDVD HLASDNKLVI
960
KKLESNASAE EMAA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP002685 Genomic DNA Translation: AEC07662.1 AY070722 mRNA Translation: AAL50064.1 BT002223 mRNA Translation: AAN72234.1 |
PIRi | G84644 |
RefSeqi | NP_565586.1, NM_128071.3 |
Genome annotation databases
EnsemblPlantsi | AT2G25140.1; AT2G25140.1; AT2G25140 |
GeneIDi | 817052 |
Gramenei | AT2G25140.1; AT2G25140.1; AT2G25140 |
KEGGi | ath:AT2G25140 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP002685 Genomic DNA Translation: AEC07662.1 AY070722 mRNA Translation: AAL50064.1 BT002223 mRNA Translation: AAN72234.1 |
PIRi | G84644 |
RefSeqi | NP_565586.1, NM_128071.3 |
3D structure databases
SMRi | Q8VYJ7 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 2404, 6 interactors |
IntActi | Q8VYJ7, 1 interactor |
STRINGi | 3702.AT2G25140.1 |
PTM databases
iPTMneti | Q8VYJ7 |
SwissPalmi | Q8VYJ7 |
Proteomic databases
PaxDbi | Q8VYJ7 |
PRIDEi | Q8VYJ7 |
ProteomicsDBi | 246654 |
Genome annotation databases
EnsemblPlantsi | AT2G25140.1; AT2G25140.1; AT2G25140 |
GeneIDi | 817052 |
Gramenei | AT2G25140.1; AT2G25140.1; AT2G25140 |
KEGGi | ath:AT2G25140 |
Organism-specific databases
Araporti | AT2G25140 |
TAIRi | locus:2040159, AT2G25140 |
Phylogenomic databases
eggNOGi | KOG1051, Eukaryota |
HOGENOMi | CLU_005070_4_2_1 |
InParanoidi | Q8VYJ7 |
OMAi | YEVFHGV |
OrthoDBi | 611758at2759 |
PhylomeDBi | Q8VYJ7 |
Miscellaneous databases
PROi | PR:Q8VYJ7 |
Gene expression databases
ExpressionAtlasi | Q8VYJ7, baseline and differential |
Genevisiblei | Q8VYJ7, AT |
Family and domain databases
Gene3Di | 1.10.1780.10, 1 hit |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003959, ATPase_AAA_core IPR017730, Chaperonin_ClpB IPR019489, Clp_ATPase_C IPR036628, Clp_N_dom_sf IPR004176, Clp_R_dom IPR001270, ClpA/B IPR018368, ClpA/B_CS1 IPR028299, ClpA/B_CS2 IPR041546, ClpA/ClpB_AAA_lid IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00004, AAA, 1 hit PF07724, AAA_2, 1 hit PF17871, AAA_lid_9, 1 hit PF02861, Clp_N, 2 hits PF10431, ClpB_D2-small, 1 hit |
PRINTSi | PR00300, CLPPROTEASEA |
SMARTi | View protein in SMART SM00382, AAA, 2 hits SM01086, ClpB_D2-small, 1 hit |
SUPFAMi | SSF52540, SSF52540, 2 hits SSF81923, SSF81923, 1 hit |
TIGRFAMsi | TIGR03346, chaperone_ClpB, 1 hit |
PROSITEi | View protein in PROSITE PS51903, CLP_R, 1 hit PS00870, CLPAB_1, 1 hit PS00871, CLPAB_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CLPB4_ARATH | |
Accessioni | Q8VYJ7Primary (citable) accession number: Q8VYJ7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 21, 2011 |
Last sequence update: | March 1, 2002 | |
Last modified: | April 7, 2021 | |
This is version 132 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families