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Entry version 114 (11 Dec 2019)
Sequence version 1 (01 Mar 2002)
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Protein

Ureidoglycolate hydrolase

Gene

UAH

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in the catabolism of purine nucleotides. Can use (S)-ureidoglycolate as substrate, but not (R)-ureidoglycolate or allantoate. The sequential activity of AAH, UGLYAH and UAH allows a complete purine breakdown without the intermediate generation of urea.3 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mn2+1 Publication, Ni2+1 Publication, Co2+1 PublicationNote: Binds 2 manganese ions per subunit. Can also use nickel and cobalt with lower activity.1 Publication

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

kcat is 1.43 sec(-1) with (S)-ureidoglycolate as substrate (at pH 8.5 and 30 degrees Celsius) (PubMed:25020232). kcat is 7.9 sec(-1) for (S)-ureidoglycolate (PubMed:19935661).2 Publications
  1. KM=38.7 µM for (S)-ureidoglycolate1 Publication
  2. KM=11.3 µM for (S)-ureidoglycolate (at pH 8.5 and 30 degrees Celsius)1 Publication

    <p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: (S)-allantoin degradation

    This protein is involved in step 1 of the subpathway that synthesizes glyoxylate from (S)-ureidoglycolate.2 Publications
    Proteins known to be involved in this subpathway in this organism are:
    1. Ureidoglycolate hydrolase (UAH)
    This subpathway is part of the pathway (S)-allantoin degradation, which is itself part of Nitrogen metabolism.
    View all proteins of this organism that are known to be involved in the subpathway that synthesizes glyoxylate from (S)-ureidoglycolate, the pathway (S)-allantoin degradation and in Nitrogen metabolism.

    Sites

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi138Manganese 1; via tele nitrogenCombined sources1 Publication1
    Metal bindingi149Manganese 1; catalyticCombined sources1 Publication1
    Metal bindingi149Manganese 2Combined sources1 Publication1
    Metal bindingi184Manganese 2Combined sources1 Publication1
    Metal bindingi254Manganese 1; via tele nitrogenCombined sources1 Publication1
    <p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei290SubstrateCombined sources1 Publication1
    <p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei299Necessary for dimerizationBy similarity1
    Binding sitei340SubstrateCombined sources1 Publication1
    Binding sitei353SubstrateCombined sources1 Publication1
    Metal bindingi448Manganese 2; via tele nitrogenCombined sources1 Publication1
    Binding sitei448SubstrateCombined sources1 Publication1

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    • manganese ion binding Source: UniProtKB
    • ureidoglycolate hydrolase activity Source: UniProtKB

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionHydrolase
    Biological processPurine metabolism
    LigandManganese, Metal-binding

    Enzyme and pathway databases

    BioCyc Collection of Pathway/Genome Databases

    More...
    BioCyci
    ARA:AT5G43600-MONOMER
    MetaCyc:AT5G43600-MONOMER

    UniPathway: a resource for the exploration and annotation of metabolic pathways

    More...
    UniPathwayi
    UPA00395;UER00656

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Ureidoglycolate hydrolase1 Publication (EC:3.5.1.1162 Publications)
    Short name:
    AtUAH1 Publication
    Alternative name(s):
    Allantoate amidohydrolase 21 Publication
    Short name:
    AtAHH21 Publication
    Ureidoglycolate amidohydrolase1 Publication
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:UAH1 Publication
    Synonyms:AAH21 Publication
    Ordered Locus Names:At5g43600Imported
    ORF Names:K9D7.10Imported
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

    Organism-specific databases

    Arabidopsis Information Portal

    More...
    Araporti
    AT5G43600

    The Arabidopsis Information Resource

    More...
    TAIRi
    locus:2158342 AT5G43600

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

    Keywords - Cellular componenti

    Endoplasmic reticulum

    <p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

    <p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

    No visible phenotype under normal growth conditions, but mutant plants show a slight reduction of growth on a medium containing allantoin as the sole nitrogen source and accumulate ureidoglycolate.1 Publication

    Mutagenesis

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi138H → A: Impaired enzyme activity. 1 Publication1
    Mutagenesisi149D → A or N: Impaired enzyme activity. 1 Publication1
    Mutagenesisi183E → A, D or Q: Impaired enzyme activity. 1 Publication1
    Mutagenesisi184E → A: Impaired enzyme activity. 1 Publication1
    Mutagenesisi254H → A: Impaired enzyme activity. 1 Publication1
    Mutagenesisi257Q → A or E: Impaired enzyme activity. 1 Publication1
    Mutagenesisi257Q → N: Strongly reduced substrate affinity and enzyme activity. 1 Publication1
    Mutagenesisi290H → A or N: Impaired enzyme activity. 1 Publication1
    Mutagenesisi290H → Q: Strongly reduced substrate affinity and enzyme activity. 1 Publication1
    Mutagenesisi340N → A: Strongly reduced substrate affinity and abolished enzyme activity. 1 Publication1
    Mutagenesisi340N → D: Impaired enzyme activity. 1 Publication1
    Mutagenesisi351D → A: Impaired enzyme activity. 1 Publication1
    Mutagenesisi353R → A or K: Impaired enzyme activity. 1 Publication1
    Mutagenesisi423Y → A or G: Impaired enzyme activity. 1 Publication1
    Mutagenesisi423Y → F: Reduced substrate affinity and enzyme activity. 1 Publication1
    Mutagenesisi424H → N: Reduced substrate affinity and enzyme activity. 1 Publication1
    Mutagenesisi448H → A: Impaired enzyme activity. 1 Publication1

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 25Sequence analysisAdd BLAST25
    <p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000042344626 – 476Ureidoglycolate hydrolaseAdd BLAST451

    Proteomic databases

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    Q8VXY9

    PRoteomics IDEntifications database

    More...
    PRIDEi
    Q8VXY9

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    Gene expression databases

    ExpressionAtlas, Differential and Baseline Expression

    More...
    ExpressionAtlasi
    Q8VXY9 baseline and differential

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...
    Genevisiblei
    Q8VXY9 AT

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    <p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

    Homodimer.

    1 Publication

    Protein-protein interaction databases

    The Biological General Repository for Interaction Datasets (BioGrid)

    More...
    BioGridi
    19630, 1 interactor

    STRING: functional protein association networks

    More...
    STRINGi
    3702.AT5G43600.1

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    Secondary structure

    1476
    Legend: HelixTurnBeta strandPDB Structure known for this area
    Show more details

    3D structure databases

    SWISS-MODEL Repository - a database of annotated 3D protein structure models

    More...
    SMRi
    Q8VXY9

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    Protein Data Bank in Europe - Knowledge Base

    More...
    PDBe-KBi
    Search...

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Region

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni183 – 184Substrate bindingCombined sources1 Publication2
    Regioni254 – 257Substrate bindingCombined sources1 Publication4
    Regioni276 – 391Involved in dimerization1 PublicationAdd BLAST116
    Regioni423 – 424Substrate bindingCombined sources1 Publication2

    <p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Belongs to the peptidase M20 family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    ENOG410IF7Y Eukaryota
    COG0624 LUCA

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    HOG000241291

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    Q8VXY9

    KEGG Orthology (KO)

    More...
    KOi
    K18151

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    IWPHGRW

    Database of Orthologous Groups

    More...
    OrthoDBi
    529725at2759

    Database for complete collections of gene phylogenies

    More...
    PhylomeDBi
    Q8VXY9

    Family and domain databases

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR010158 Amidase_Cbmase
    IPR036264 Bact_exopeptidase_dim_dom
    IPR002933 Peptidase_M20

    The PANTHER Classification System

    More...
    PANTHERi
    PTHR32494 PTHR32494, 1 hit

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF01546 Peptidase_M20, 1 hit

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF55031 SSF55031, 1 hit

    TIGRFAMs; a protein family database

    More...
    TIGRFAMsi
    TIGR01879 hydantase, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

    Q8VXY9-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MESLKRFLCS IALLLISLLL PSSLAQQQQH ESIRTMEDFS GYPIHEPGQF
    60 70 80 90 100
    GSINLASSLS VDAPGLQNQI DELSSFSDAP SPSVTRVLYT DKDVSARRYV
    110 120 130 140 150
    KNLMALAGLT VREDAVGNIF GKWDGLEPNL PAVATGSHID AIPYSGKYDG
    160 170 180 190 200
    VVGVLGAIEA INVLKRSGFK PKRSLEIILF TSEEPTRFGI SCLGSRLLAG
    210 220 230 240 250
    SKELAEALKT TVVDGQNVSF IEAARSAGYA EDKDDDLSSV FLKKGSYFAF
    260 270 280 290 300
    LELHIEQGPI LEDEGLDIGV VTAIAAPASL KVEFEGNGGH AGAVLMPYRN
    310 320 330 340 350
    DAGLAAAELA LAVEKHVLES ESIDTVGTVG ILELHPGAIN SIPSKSHLEI
    360 370 380 390 400
    DTRDIDEARR NTVIKKIQES ANTIAKKRKV KLSEFKIVNQ DPPALSDKLV
    410 420 430 440 450
    IKKMAEAATE LNLSHKMMIS RAYHDSLFMA RISPMGMIFI PCYKGYSHKP
    460 470
    EEYSSPEDMA NGVKVLSLTL AKLSLD
    Length:476
    Mass (Da):51,487
    Last modified:March 1, 2002 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCBAEB842B3B0BC0F
    GO

    <p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

    The sequence BAB11623 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    AB016875 Genomic DNA Translation: BAB11623.1 Different initiation.
    CP002688 Genomic DNA Translation: AED94986.1
    AY074343 mRNA Translation: AAL67039.1
    AY091387 mRNA Translation: AAM14326.1
    AK230338 mRNA Translation: BAF02137.1

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_199173.2, NM_123726.4

    Genome annotation databases

    Ensembl plant genome annotation project

    More...
    EnsemblPlantsi
    AT5G43600.1; AT5G43600.1; AT5G43600

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    834380

    Gramene; a comparative resource for plants

    More...
    Gramenei
    AT5G43600.1; AT5G43600.1; AT5G43600

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    ath:AT5G43600

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AB016875 Genomic DNA Translation: BAB11623.1 Different initiation.
    CP002688 Genomic DNA Translation: AED94986.1
    AY074343 mRNA Translation: AAL67039.1
    AY091387 mRNA Translation: AAM14326.1
    AK230338 mRNA Translation: BAF02137.1
    RefSeqiNP_199173.2, NM_123726.4

    3D structure databases

    Select the link destinations:

    Protein Data Bank Europe

    More...
    PDBei

    Protein Data Bank RCSB

    More...
    RCSB PDBi

    Protein Data Bank Japan

    More...
    PDBji
    Links Updated
    PDB entryMethodResolution (Å)ChainPositionsPDBsum
    4PXBX-ray1.90A/B50-476[»]
    4PXCX-ray1.89A/B50-476[»]
    4PXEX-ray1.45A/B50-476[»]
    SMRiQ8VXY9
    ModBaseiSearch...
    PDBe-KBiSearch...

    Protein-protein interaction databases

    BioGridi19630, 1 interactor
    STRINGi3702.AT5G43600.1

    Proteomic databases

    PaxDbiQ8VXY9
    PRIDEiQ8VXY9

    Genome annotation databases

    EnsemblPlantsiAT5G43600.1; AT5G43600.1; AT5G43600
    GeneIDi834380
    GrameneiAT5G43600.1; AT5G43600.1; AT5G43600
    KEGGiath:AT5G43600

    Organism-specific databases

    AraportiAT5G43600
    TAIRilocus:2158342 AT5G43600

    Phylogenomic databases

    eggNOGiENOG410IF7Y Eukaryota
    COG0624 LUCA
    HOGENOMiHOG000241291
    InParanoidiQ8VXY9
    KOiK18151
    OMAiIWPHGRW
    OrthoDBi529725at2759
    PhylomeDBiQ8VXY9

    Enzyme and pathway databases

    UniPathwayiUPA00395;UER00656
    BioCyciARA:AT5G43600-MONOMER
    MetaCyc:AT5G43600-MONOMER

    Miscellaneous databases

    Protein Ontology

    More...
    PROi
    PR:Q8VXY9

    Gene expression databases

    ExpressionAtlasiQ8VXY9 baseline and differential
    GenevisibleiQ8VXY9 AT

    Family and domain databases

    InterProiView protein in InterPro
    IPR010158 Amidase_Cbmase
    IPR036264 Bact_exopeptidase_dim_dom
    IPR002933 Peptidase_M20
    PANTHERiPTHR32494 PTHR32494, 1 hit
    PfamiView protein in Pfam
    PF01546 Peptidase_M20, 1 hit
    SUPFAMiSSF55031 SSF55031, 1 hit
    TIGRFAMsiTIGR01879 hydantase, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiUAH_ARATH
    <p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8VXY9
    Secondary accession number(s): Q9FIY0
    <p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 18, 2013
    Last sequence update: March 1, 2002
    Last modified: December 11, 2019
    This is version 114 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    <p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    3D-structure, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families
    4. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    5. Peptidase families
      Classification of peptidase families and list of entries
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