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Entry version 97 (07 Oct 2020)
Sequence version 2 (22 Nov 2005)
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Protein

Putative potassium transporter 8

Gene

HAK8

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

High-affinity potassium transporter.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processIon transport, Potassium transport, Transport
LigandPotassium

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative potassium transporter 8
Alternative name(s):
OsHAK8
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:HAK8
Ordered Locus Names:Os03g0337500, LOC_Os03g21890
ORF Names:OsJ_10761
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOryza sativa subsp. japonica (Rice)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri39947 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007752 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3
  • UP000059680 Componenti: Chromosome 3
  • UP000000763 Componenti: Chromosome 3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 22CytoplasmicSequence analysisAdd BLAST22
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei23 – 43Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini44 – 59ExtracellularSequence analysisAdd BLAST16
Transmembranei60 – 80Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini81 – 151CytoplasmicSequence analysisAdd BLAST71
Transmembranei152 – 172Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini173 – 191ExtracellularSequence analysisAdd BLAST19
Transmembranei192 – 212Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini213 – 215CytoplasmicSequence analysis3
Transmembranei216 – 236Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini237 – 264ExtracellularSequence analysisAdd BLAST28
Transmembranei265 – 285Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini286 – 292CytoplasmicSequence analysis7
Transmembranei293 – 313Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini314 – 343ExtracellularSequence analysisAdd BLAST30
Transmembranei344 – 364Helical; Name=8Sequence analysisAdd BLAST21
Topological domaini365 – 391CytoplasmicSequence analysisAdd BLAST27
Transmembranei392 – 412Helical; Name=9Sequence analysisAdd BLAST21
Topological domaini413 – 422ExtracellularSequence analysis10
Transmembranei423 – 443Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini444 – 448CytoplasmicSequence analysis5
Transmembranei449 – 469Helical; Name=11Sequence analysisAdd BLAST21
Topological domaini470 – 473ExtracellularSequence analysis4
Transmembranei474 – 494Helical; Name=12Sequence analysisAdd BLAST21
Topological domaini495 – 793CytoplasmicSequence analysisAdd BLAST299

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002090951 – 793Putative potassium transporter 8Add BLAST793

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi420N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8VXB5

PRoteomics IDEntifications database

More...
PRIDEi
Q8VXB5

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
4530.OS03T0337500-00

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8VXB5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QPSA, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8VXB5

KEGG Orthology (KO)

More...
KOi
K03549

Database of Orthologous Groups

More...
OrthoDBi
332035at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003855, K+_transporter

The PANTHER Classification System

More...
PANTHERi
PTHR30540, PTHR30540, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02705, K_trans, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00794, kup, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q8VXB5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDLEFGRGMR SPQRDSWKTT LLLAYQSLGV VYGDLSISPL YVFKSTFAED
60 70 80 90 100
IQHSETNEEI FGVLSFVFWT LTLIPLIKYV SIVLRADDNG EGGTFALYSL
110 120 130 140 150
ICRHANVSLL PNRQIADEEL STYKLECSSE RTDKSCIKVW LEKHKKLHTA
160 170 180 190 200
LLIMVLIGTC MVIGDGVLTP AISVFSAVSG LEFSLSKDHR EYAVIPITCV
210 220 230 240 250
ILAFLFALQH YGTHRVGFLF APIVLAWLIC MSALGLYNII HWNPHVYQAL
260 270 280 290 300
NPCYMFKFLK KTRKYGWMSL GGILLCMTGS EAMFADLGHF SYSAIQLAFT
310 320 330 340 350
SLVYPALILA YMGQAAYLSK HHDFYSNSQV GFYIAVPDKV RWPVLVLAIL
360 370 380 390 400
ASVVGSQAII SGTFSIINQS QSLSCFPRVK VVHTSDKIHG QIYIPEINWL
410 420 430 440 450
LMILCIAVTV GFRDTKHMGN ASGLAVITVM LVTTCLTSLV IMLCWRRPPV
460 470 480 490 500
LALCFLLFFG SVEALYFSAS LIKFLEGAWL PILLALFLMA VMLVWHYTTI
510 520 530 540 550
KKYEFDLHNK VTLEWLLALG DKLGMVRVPG IGLVYTDLTS GVPANFSRFV
560 570 580 590 600
TNLPAFHQVL VFVCVKSVPV PYVFPAERYL IGRVGPPGHR SYRCIVRYGY
610 620 630 640 650
RDVHQDVDSF ETELVESLAT FIKLDASYRC SDASGGGGDH EPEEERGTRL
660 670 680 690 700
AVIGSSHASY DIQDSVQHSS AASVETTTTR RRSGGGDDDG SPGGGGGRAK
710 720 730 740 750
QVRFFIDSHV ASPEAADNKQ VAEELEALAA ARDAGTAFIL GHSHVQCKPG
760 770 780 790
SSLLKRLAVD VGYNFLRRNC RGPDVALRVP PASLLEVGMV YVL
Length:793
Mass (Da):87,653
Last modified:November 22, 2005 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2C5A1C69EAF180F7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0P0VX74A0A0P0VX74_ORYSJ
Potassium transporter
Os03g0337500, OSNPB_030337500
867Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAF11962 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC134885 Genomic DNA No translation available.
DP000009 Genomic DNA Translation: ABF95828.1
AP008209 Genomic DNA Translation: BAF11962.1 Sequence problems.
AP014959 Genomic DNA No translation available.
CM000140 Genomic DNA Translation: EAZ26845.1
AJ427977 Genomic DNA Translation: CAD20998.1

NCBI Reference Sequences

More...
RefSeqi
XP_015630461.1, XM_015774975.1
XP_015630462.1, XM_015774976.1
XP_015630463.1, XM_015774977.1
XP_015630464.1, XM_015774978.1
XP_015630465.1, XM_015774979.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
9271735

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
osa:9271735

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC134885 Genomic DNA No translation available.
DP000009 Genomic DNA Translation: ABF95828.1
AP008209 Genomic DNA Translation: BAF11962.1 Sequence problems.
AP014959 Genomic DNA No translation available.
CM000140 Genomic DNA Translation: EAZ26845.1
AJ427977 Genomic DNA Translation: CAD20998.1
RefSeqiXP_015630461.1, XM_015774975.1
XP_015630462.1, XM_015774976.1
XP_015630463.1, XM_015774977.1
XP_015630464.1, XM_015774978.1
XP_015630465.1, XM_015774979.1

3D structure databases

SMRiQ8VXB5
ModBaseiSearch...

Protein-protein interaction databases

STRINGi4530.OS03T0337500-00

Proteomic databases

PaxDbiQ8VXB5
PRIDEiQ8VXB5

Genome annotation databases

GeneIDi9271735
KEGGiosa:9271735

Phylogenomic databases

eggNOGiENOG502QPSA, Eukaryota
InParanoidiQ8VXB5
KOiK03549
OrthoDBi332035at2759

Family and domain databases

InterProiView protein in InterPro
IPR003855, K+_transporter
PANTHERiPTHR30540, PTHR30540, 1 hit
PfamiView protein in Pfam
PF02705, K_trans, 1 hit
TIGRFAMsiTIGR00794, kup, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiHAK8_ORYSJ
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8VXB5
Secondary accession number(s): Q0DS26, Q10LS0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 22, 2005
Last modified: October 7, 2020
This is version 97 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families
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