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Protein

Cysteine and tyrosine-rich protein 1

Gene

Cyyr1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Cysteine and tyrosine-rich protein 1
Alternative name(s):
Proline-rich domain-containing protein
Gene namesi
Name:Cyyr1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:2152187 Cyyr1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini30 – 61ExtracellularSequence analysisAdd BLAST32
Transmembranei62 – 82HelicalSequence analysisAdd BLAST21
Topological domaini83 – 165CytoplasmicSequence analysisAdd BLAST83

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 29Sequence analysisAdd BLAST29
ChainiPRO_000002105530 – 165Cysteine and tyrosine-rich protein 1Add BLAST136

Proteomic databases

MaxQBiQ8VIH7
PaxDbiQ8VIH7
PRIDEiQ8VIH7

PTM databases

iPTMnetiQ8VIH7
PhosphoSitePlusiQ8VIH7

Expressioni

Gene expression databases

BgeeiENSMUSG00000041134 Expressed in 179 organ(s), highest expression level in brain blood vessel
CleanExiMM_CYYR1
ExpressionAtlasiQ8VIH7 baseline and differential
GenevisibleiQ8VIH7 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000109811

Structurei

3D structure databases

ProteinModelPortaliQ8VIH7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi144 – 149Poly-Pro6

Sequence similaritiesi

Belongs to the CYYR1 family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IWAY Eukaryota
ENOG4111TRP LUCA
GeneTreeiENSGT00500000044986
HOGENOMiHOG000015276
HOVERGENiHBG051282
InParanoidiQ8VIH7
OMAiCMCMKNN
OrthoDBiEOG091G15ZN
PhylomeDBiQ8VIH7
TreeFamiTF332064

Family and domain databases

InterProiView protein in InterPro
IPR022640 CYYR1
PANTHERiPTHR38490 PTHR38490, 1 hit
PfamiView protein in Pfam
PF10873 CYYR1, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD588499 PD588499, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q8VIH7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDALRLPRRP GVLLPKLILL FVYAGDCLAQ CGKECHSYCC DGSTPYCCSY
60 70 80 90 100
YAYIGNILSG TAIAGIVFGI VFIMGVIAGI AICICMCMKN NRGTRVGVIR
110 120 130 140 150
AAHINAISYP MAPPPYTYDH EMEYRTDLPP PYSAAPQASA QRSPPPPYPG
160
NPRKYSSSQN RIRDN
Length:165
Mass (Da):18,044
Last modified:October 3, 2012 - v2
Checksum:i169DC2BF02BCFDD4
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H3BKF0H3BKF0_MOUSE
Cysteine and tyrosine-rich protein ...
Cyyr1
68Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti36H → R in AAL35295 (PubMed:12062809).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF442733 mRNA Translation: AAL35295.1
AY061854 mRNA Translation: AAL35738.1
AC154622 Genomic DNA No translation available.
CT025589 Genomic DNA No translation available.
BC099957 mRNA Translation: AAH99957.1
BC125594 mRNA Translation: AAI25595.1
BC125596 mRNA Translation: AAI25597.1
CCDSiCCDS28286.1
RefSeqiNP_659102.1, NM_144853.3
XP_006523068.1, XM_006523005.1
UniGeneiMm.213203
Mm.451566

Genome annotation databases

EnsembliENSMUST00000114174; ENSMUSP00000109811; ENSMUSG00000041134
GeneIDi224405
KEGGimmu:224405
UCSCiuc007ztu.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF442733 mRNA Translation: AAL35295.1
AY061854 mRNA Translation: AAL35738.1
AC154622 Genomic DNA No translation available.
CT025589 Genomic DNA No translation available.
BC099957 mRNA Translation: AAH99957.1
BC125594 mRNA Translation: AAI25595.1
BC125596 mRNA Translation: AAI25597.1
CCDSiCCDS28286.1
RefSeqiNP_659102.1, NM_144853.3
XP_006523068.1, XM_006523005.1
UniGeneiMm.213203
Mm.451566

3D structure databases

ProteinModelPortaliQ8VIH7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000109811

PTM databases

iPTMnetiQ8VIH7
PhosphoSitePlusiQ8VIH7

Proteomic databases

MaxQBiQ8VIH7
PaxDbiQ8VIH7
PRIDEiQ8VIH7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000114174; ENSMUSP00000109811; ENSMUSG00000041134
GeneIDi224405
KEGGimmu:224405
UCSCiuc007ztu.2 mouse

Organism-specific databases

CTDi116159
MGIiMGI:2152187 Cyyr1

Phylogenomic databases

eggNOGiENOG410IWAY Eukaryota
ENOG4111TRP LUCA
GeneTreeiENSGT00500000044986
HOGENOMiHOG000015276
HOVERGENiHBG051282
InParanoidiQ8VIH7
OMAiCMCMKNN
OrthoDBiEOG091G15ZN
PhylomeDBiQ8VIH7
TreeFamiTF332064

Miscellaneous databases

ChiTaRSiCyyr1 mouse
PROiPR:Q8VIH7
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000041134 Expressed in 179 organ(s), highest expression level in brain blood vessel
CleanExiMM_CYYR1
ExpressionAtlasiQ8VIH7 baseline and differential
GenevisibleiQ8VIH7 MM

Family and domain databases

InterProiView protein in InterPro
IPR022640 CYYR1
PANTHERiPTHR38490 PTHR38490, 1 hit
PfamiView protein in Pfam
PF10873 CYYR1, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD588499 PD588499, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCYYR1_MOUSE
AccessioniPrimary (citable) accession number: Q8VIH7
Secondary accession number(s): Q499D9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 13, 2002
Last sequence update: October 3, 2012
Last modified: September 12, 2018
This is version 102 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health

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