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Entry version 144 (29 Sep 2021)
Sequence version 1 (01 Mar 2002)
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Protein

Spectrin beta chain

Gene

Sptbn4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin cappingUniRule annotationARBA annotation, Actin-bindingUniRule annotationARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Spectrin beta chainUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Sptbn4Imported
Synonyms:Spnb4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1890574, Sptbn4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, CytoskeletonUniRule annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
Q8VIE5

PRoteomics IDEntifications database

More...
PRIDEi
Q8VIE5

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8VIE5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8VIE5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8VIE5, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini62 – 166Calponin-homology (CH)InterPro annotationAdd BLAST105
Domaini181 – 286Calponin-homology (CH)InterPro annotationAdd BLAST106
Domaini2415 – 2524PHInterPro annotationAdd BLAST110

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 38DisorderedSequence analysisAdd BLAST38
Regioni1849 – 1868DisorderedSequence analysisAdd BLAST20
Regioni2183 – 2429DisorderedSequence analysisAdd BLAST247
Regioni2530 – 2561DisorderedSequence analysisAdd BLAST32

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili121 – 141Sequence analysisAdd BLAST21
Coiled coili465 – 499Sequence analysisAdd BLAST35
Coiled coili627 – 647Sequence analysisAdd BLAST21
Coiled coili737 – 771Sequence analysisAdd BLAST35
Coiled coili1121 – 1141Sequence analysisAdd BLAST21
Coiled coili1441 – 1468Sequence analysisAdd BLAST28
Coiled coili1659 – 1686Sequence analysisAdd BLAST28
Coiled coili2012 – 2032Sequence analysisAdd BLAST21
Coiled coili2079 – 2099Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi2224 – 2310Basic and acidic residuesSequence analysisAdd BLAST87
Compositional biasi2338 – 2360Pro residuesSequence analysisAdd BLAST23

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the spectrin family.UniRule annotationARBA annotation

Keywords - Domaini

Coiled coilSequence analysis, RepeatARBA annotation

Phylogenomic databases

Identification of Orthologs from Complete Genome Data

More...
OMAi
SPECGQH

Database of Orthologous Groups

More...
OrthoDBi
543832at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00014, CH, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.418.10, 2 hits
2.30.29.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001589, Actinin_actin-bd_CS
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR011993, PH-like_dom_sf
IPR041681, PH_9
IPR001605, PH_dom-spectrin-type
IPR001849, PH_domain
IPR018159, Spectrin/alpha-actinin
IPR016343, Spectrin_bsu
IPR002017, Spectrin_repeat

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00307, CH, 2 hits
PF15410, PH_9, 1 hit
PF00435, Spectrin, 14 hits

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002297, Spectrin_beta_subunit, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00683, SPECTRINPH

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00033, CH, 2 hits
SM00233, PH, 1 hit
SM00150, SPEC, 16 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47576, SSF47576, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00019, ACTININ_1, 1 hit
PS00020, ACTININ_2, 1 hit
PS50021, CH, 2 hits
PS50003, PH_DOMAIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8VIE5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAQVPGEVDN MEGPAVSNNN NPSARWESPD RGWDREPPAA ANAAASLFEC
60 70 80 90 100
SRIKALADER EAVQKKTFTK WVNSHLARVG CHIGDLYADL RDGFVLTRLL
110 120 130 140 150
EVLSGEQLPR PTRGRMRIHS LENVDKALQF LKEQRVHLEN VGSHDIVDGN
160 170 180 190 200
HRLTLGLVWT IILRFQIQVI KIETEDNRET RSAKDALLLW CQMKTAGYPE
210 220 230 240 250
VNIQNFTTSW RDGLAFNALI HRHRPDLVDL SKLTKSNANY NLQRAFRTAE
260 270 280 290 300
QHLGLARLLD PEDVNMEAPD EKSIITYVVS FYHYFSKMKA LAVEGKRIGK
310 320 330 340 350
VLDQVLEVDK IIERYEELAA ELLAWIHRTV DLISNQKFAN SLSGVQQQLQ
360 370 380 390 400
AFTAYCTLEK PVKFQEKGNL EVLLFSIQSK LRAHNRRLFV PREGCGIWDI
410 420 430 440 450
DKAWGELEKA EHEREAALRA ELIRQEKLEL LAQRFDHKVA MRESWLNENQ
460 470 480 490 500
RLVSQDNFGY ELPAVEAAMK KHEAIEADIA AYEERVQGVA ELAQALAAEG
510 520 530 540 550
YYDARRVAAQ RDSVLRQWAL LTGLVGARRT RLEQNLALQK VFQEMVYMVD
560 570 580 590 600
WMEEMQTQLL SRECGQHLVE ADDLLQKHGL LEGDIAAQSE RVEALNAAAL
610 620 630 640 650
RFSQLQGYQP CDPQVICNRV NHVHGCLSEL QEQAARRRAE LEASRSLWAL
660 670 680 690 700
LQELEEAESW ARDKERLLEA TSGSGGAAGT AGGAHDLSST ARLLAQHKIL
710 720 730 740 750
QGELGGRRAL LQQALRRGEE LAAAGGSVGP GAEPLHLAGL AERAASARRR
760 770 780 790 800
WQRLEEAAAR RERRLQEARA LHQFGADLDG LLDWLRDAYR LAAAGDFGHD
810 820 830 840 850
EASSRRLARQ HRALTGEVEA HRGPVGGLRR QLATLGGASG AGPLVVALQV
860 870 880 890 900
RVVEAEQLFA EVTEVAALRR QWLRDALAVY RMFGEVHACE LWIGEKEQWL
910 920 930 940 950
LAMRVPDSLD DVEVVQHRFE SLDQEMNSLM GRVLDVNQTV QELVEGGHPS
960 970 980 990 1000
SDEVRSCQDH LNSRWNRIVE LVEQRKEEMS AVLLVENHVL EVAEVRAQVR
1010 1020 1030 1040 1050
EKRRAVESAP RAGGALQWRL SGLEAALQAL EPRQAALLEE AALLAERFPA
1060 1070 1080 1090 1100
QATRLHQGAE ELGAEWGALA GAAQACGEAV AAAGRLQRFL RDLDTFLDWL
1110 1120 1130 1140 1150
VRAQEAAGAV EGPLPRSLEE ADGLLARHAA LKEEVDQREE DYARIVAASE
1160 1170 1180 1190 1200
ALLASEGAEL GPGLALDEWL PHLEVGWHKL LGLWEERREA LVQAHVYQLF
1210 1220 1230 1240 1250
LRDLCQALAV LRNQEVALSG AELPCTVESV EEAMKRHRDF LTTMELNQQK
1260 1270 1280 1290 1300
MQVAVQAAES LLRQGNAYGE QAQEAVARLL EKSQENQLRA QQWMQKLLDQ
1310 1320 1330 1340 1350
LVLQHFLRDC HELDGWIHEK MLMARDGTRE DSHKLHKRWL RHQAFMAELA
1360 1370 1380 1390 1400
QNKEWLEKIE REGQQLMQEK PELAASVRKK LGEIRQCWAE LESTTQAKAR
1410 1420 1430 1440 1450
QLFEASKADQ LVQSFAELDK RLLHMESQLQ DVDPGGDLAT VNSQLKKLQS
1460 1470 1480 1490 1500
MESQVEEWCR EVGELQAQTA ALPLEQASKE LVGERQSAVG ERLVRLLEPL
1510 1520 1530 1540 1550
QERRRLLLAS KELHQVAHDL DDELAWVQER LPLAMQTERG TGLQAVQQHI
1560 1570 1580 1590 1600
KKNQGLRREI QAHGPRLEEV LERAGVLASL RSPEAEAVRR GQEQLQSAWT
1610 1620 1630 1640 1650
GLREAAERRQ QTLDAAFQVE QYYFDVAEVE AWLGEQELLM MSEDKGKDEQ
1660 1670 1680 1690 1700
STLQLLKKHL QLEQGVENYE ESIAQLSRQC RALLEMGHPD SEQISRRQSQ
1710 1720 1730 1740 1750
VDRLYVALKE LGEERRVSLE QQYWLYQLSR QVDELEHWIA EKEVVAGSPE
1760 1770 1780 1790 1800
LGQDFEHVSV LQEKFSEFAS ETGTAGRERL AAVNQMVDEL IECGHTAAAT
1810 1820 1830 1840 1850
MAEWKDGLNE AWAELLELMG TRAQLLAASR ELHKFFSDAR ELQGQIEEKR
1860 1870 1880 1890 1900
RRLPRLTAPP EPRPSASSMQ RTLRAFEHDL QLLVSQVRQL QEGAAQLRTV
1910 1920 1930 1940 1950
YAGEHAEAIA SREQEVLQGW KELLAACEDA RLHVSSTADA LRFHSQARDL
1960 1970 1980 1990 2000
LSWMDGIAGQ IGAADKPRDV SSVEVLMNYH QGLKTELEAR VPELAACQEL
2010 2020 2030 2040 2050
GRSLLLNKSA MADEIQAQLD KLGSRKEEVS EKWDRHWEWL QQMLEVHQFA
2060 2070 2080 2090 2100
QEAVVADAWL TAQEPLLQSR ELGSSVDEVE QLIRRHEAFR KAAAAWEERF
2110 2120 2130 2140 2150
SSLRRLTTIE KLKAEQSKQP PTPLLGRKFF GDPTELAAKA APLLRPGGYD
2160 2170 2180 2190 2200
RGLEPLARRA SDTLSAEVRT RVGYVRQELK PERLQPRIDR LPETSGKVEP
2210 2220 2230 2240 2250
AAPTAAALDT TDTPGTPAAT EQVRPRSERQ ELADRAEELP RRRRSERQES
2260 2270 2280 2290 2300
VDQPEETARR RRPERQESAD HEGPHSLTLG RYEQMERRRE RRERRIERQE
2310 2320 2330 2340 2350
SSEQETPTRG ELVKGKATLA DIVEQLQEKE AGPGIPAGVP SLPQPRELPP
2360 2370 2380 2390 2400
GRLPNGLEPP ERTPRPDRPR ARDRPKPRRR PRPREGGEGG GSRRSRSAPA
2410 2420 2430 2440 2450
QGGSAPAPPP PPTHTVQHEG FLLRKRELDA NRKSSNRSWV SLYCVLSKGE
2460 2470 2480 2490 2500
LGFYKDSKGP ASGGTHGGEP LLSLHKATSE VASDYKKKKH VFKLQTQDGS
2510 2520 2530 2540 2550
EFLLQAKDEE EMNGWLEAVA NSVAEHAEIA RWGQTLPTTS STDEGNPKRE
2560
GGERRASGRR K
Length:2,561
Mass (Da):288,809
Last modified:March 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4DF01A9180140F33
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB055618 mRNA Translation: BAB83243.1

NCBI Reference Sequences

More...
RefSeqi
NP_115999.2, NM_032610.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
80297

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB055618 mRNA Translation: BAB83243.1
RefSeqiNP_115999.2, NM_032610.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

PTM databases

iPTMnetiQ8VIE5
PhosphoSitePlusiQ8VIE5

Proteomic databases

PeptideAtlasiQ8VIE5
PRIDEiQ8VIE5

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
80297

Genome annotation databases

GeneIDi80297

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57731
MGIiMGI:1890574, Sptbn4

Phylogenomic databases

OMAiSPECGQH
OrthoDBi543832at2759

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
80297, 2 hits in 61 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Sptbn4, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

GenevisibleiQ8VIE5, MM

Family and domain databases

CDDicd00014, CH, 2 hits
Gene3Di1.10.418.10, 2 hits
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR001589, Actinin_actin-bd_CS
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR011993, PH-like_dom_sf
IPR041681, PH_9
IPR001605, PH_dom-spectrin-type
IPR001849, PH_domain
IPR018159, Spectrin/alpha-actinin
IPR016343, Spectrin_bsu
IPR002017, Spectrin_repeat
PfamiView protein in Pfam
PF00307, CH, 2 hits
PF15410, PH_9, 1 hit
PF00435, Spectrin, 14 hits
PIRSFiPIRSF002297, Spectrin_beta_subunit, 1 hit
PRINTSiPR00683, SPECTRINPH
SMARTiView protein in SMART
SM00033, CH, 2 hits
SM00233, PH, 1 hit
SM00150, SPEC, 16 hits
SUPFAMiSSF47576, SSF47576, 1 hit
PROSITEiView protein in PROSITE
PS00019, ACTININ_1, 1 hit
PS00020, ACTININ_2, 1 hit
PS50021, CH, 2 hits
PS50003, PH_DOMAIN, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ8VIE5_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8VIE5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: September 29, 2021
This is version 144 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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