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Protein

Importin-4

Gene

Ipo4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of RPS3A. Acts as chaperone for exposed basic domains.By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • nuclear localization sequence binding Source: GO_Central
  • Ran GTPase binding Source: InterPro

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Importin-4
Short name:
Imp4
Alternative name(s):
Importin-4a
Short name:
Imp4a
Ran-binding protein 4
Short name:
RanBP4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ipo4
Synonyms:Imp4a, Ranbp4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1923001 Ipo4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001207491 – 1082Importin-4Add BLAST1082

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8VI75

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8VI75

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8VI75

PeptideAtlas

More...
PeptideAtlasi
Q8VI75

PRoteomics IDEntifications database

More...
PRIDEi
Q8VI75

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8VI75

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8VI75

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000002319 Expressed in 290 organ(s), highest expression level in internal carotid artery

CleanEx database of gene expression profiles

More...
CleanExi
MM_IPO4

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8VI75 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8VI75 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Binds with high affinity to RPS3A. The binding is coupled to RanGTP cycles. Found in a cytosolic complex with ASF1A, ASF1B, CDAN1 and histones H3.1 and H4 (By similarity).By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
217713, 3 interactors

Protein interaction database and analysis system

More...
IntActi
Q8VI75, 2 interactors

Molecular INTeraction database

More...
MINTi
Q8VI75

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000036555

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q8VI75

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8VI75

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini24 – 90Importin N-terminalPROSITE-ProRule annotationAdd BLAST67
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati348 – 385HEAT 1Add BLAST38
Repeati390 – 427HEAT 2Add BLAST38
Repeati431 – 471HEAT 3Add BLAST41
Repeati475 – 513HEAT 4Add BLAST39
Repeati896 – 933HEAT 5Add BLAST38
Repeati937 – 975HEAT 6Add BLAST39

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the importin beta family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410KD6C Eukaryota
ENOG410XP2Z LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00550000075074

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000008166

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG049052

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8VI75

KEGG Orthology (KO)

More...
KOi
K20221

Identification of Orthologs from Complete Genome Data

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OMAi
LCKTKQG

Database of Orthologous Groups

More...
OrthoDBi
EOG091G012W

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8VI75

TreeFam database of animal gene trees

More...
TreeFami
TF323157

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024 ARM-type_fold
IPR000357 HEAT
IPR001494 Importin-beta_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02985 HEAT, 1 hit
PF03810 IBN_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00913 IBN_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50166 IMPORTIN_B_NT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q8VI75-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEPAGLEQIL KELLLPDTER IRRATEQLQT ILRDPAALPA LFDLLATATD
60 70 80 90 100
SQIRQFAAVL TRRRLNNRWR RLAPEQRESL KSLVLTALQK ETVHSVSVSL
110 120 130 140 150
AQLSATIFRK EGLQGWPQFM NLLQHSTHSS HSPEKEVGLL LLSVVVSSQP
160 170 180 190 200
EAFHAHQHEL LQLLNETLSD VSFPGVLFYS LRTLTAIARY VRPDDVSLAR
210 220 230 240 250
MLVPKVVTAL RTLIPLDEVK ACEALEALDE MLETELPIIN PHLSEVLTFC
260 270 280 290 300
LEVAKNVALG EPLRVRVLCC LTFLVKVKSK ALLKNRLVPP LLHALFPLMA
310 320 330 340 350
AEPPMGQLDP EDQDSDDDDL EIGLMGETPK HFAVQVVDML ALHLPPEKLC
360 370 380 390 400
PHVMPMLEEA LRSEDPYQRK AGFLVLAVLS DGAGDHIRQR LLYPLLQIVC
410 420 430 440 450
KGLDDPSQIV RNAALFALGQ FSENLQPHIS SYSEEVMPLL LSYLKSVPMG
460 470 480 490 500
NTHHLAKACY ALENFVENLG PKVQPYLPEL MECMLQPLKN PSKARTKELA
510 520 530 540 550
VSAIGAIATA AQDSLLPYFP TIMDLLREFL LTGHEDFHLV QIQSLETLGV
560 570 580 590 600
LARALGESMK PLAEECCQLG LGLCIHIDDP DVRRCTYSLF AALSGLMGEG
610 620 630 640 650
LGPYLPQITT LMLLSLRSTE GIVPQYDGIS SFLLFDDDSE AEEEEELMDE
660 670 680 690 700
DMEEEGDDSE ISGYSVENAF FDEKEDTCTA LGEISMNTCV AFLPFMDATF
710 720 730 740 750
DEVYKLLECP HMNVRKSAYE ALGQFCCALH KASQRSSSDP SSSPVLQTSL
760 770 780 790 800
ARVMPAYMQA VKVERERPVV MAVLESLTGV LRTCGSLALQ PPGRLSELCN
810 820 830 840 850
VLKAVLQKKT ACQDAEEDDD EDDDQAEYDA MLLEHAGEAI PVLAATAGGH
860 870 880 890 900
AFAPFFATFL PLLLCKTKQS CTVAEKSFAV GTLAESIQGL GTASAQFVSR
910 920 930 940 950
LFPVLLNNAR EADPEVRSNA IFGLGVLAEH GGCPAQDHFP KLLGLLLPLL
960 970 980 990 1000
ARERHDRVRD NICGALARVL MASPVGKTEP QVLATLLRAL PLKEDMEEWL
1010 1020 1030 1040 1050
TIGHLFSFLH QNNPEQVVDV ASELLRICSL ILPDNRIPPD TKAALLLLLT
1060 1070 1080
FLAKQHTDSF HTALGSLPND KAQELQAMMG LT
Length:1,082
Mass (Da):119,275
Last modified:March 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBF78D395A3111FF3
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5U4C5Q5U4C5_MOUSE
Importin-4
Ipo4
818Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RES6D6RES6_MOUSE
Importin 4, isoform CRA_a
Ipo4 mCG_22060
98Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3BRV3A0A2I3BRV3_MOUSE
Importin-4
Ipo4
188Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3BQQ0A0A2I3BQQ0_MOUSE
Importin-4
Ipo4
74Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH03469 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAC26988 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF123388 mRNA Translation: AAL55522.1
AK030490 mRNA Translation: BAC26988.1 Different initiation.
AK147086 mRNA Translation: BAE27666.1
AK171031 mRNA Translation: BAE42197.1
BC003469 mRNA Translation: AAH03469.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS27121.1

NCBI Reference Sequences

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RefSeqi
NP_077229.4, NM_024267.6

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.27546

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000047131; ENSMUSP00000036555; ENSMUSG00000002319

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
75751

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:75751

UCSC genome browser

More...
UCSCi
uc007tzp.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF123388 mRNA Translation: AAL55522.1
AK030490 mRNA Translation: BAC26988.1 Different initiation.
AK147086 mRNA Translation: BAE27666.1
AK171031 mRNA Translation: BAE42197.1
BC003469 mRNA Translation: AAH03469.1 Different initiation.
CCDSiCCDS27121.1
RefSeqiNP_077229.4, NM_024267.6
UniGeneiMm.27546

3D structure databases

ProteinModelPortaliQ8VI75
SMRiQ8VI75
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi217713, 3 interactors
IntActiQ8VI75, 2 interactors
MINTiQ8VI75
STRINGi10090.ENSMUSP00000036555

PTM databases

iPTMnetiQ8VI75
PhosphoSitePlusiQ8VI75

Proteomic databases

EPDiQ8VI75
MaxQBiQ8VI75
PaxDbiQ8VI75
PeptideAtlasiQ8VI75
PRIDEiQ8VI75

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000047131; ENSMUSP00000036555; ENSMUSG00000002319
GeneIDi75751
KEGGimmu:75751
UCSCiuc007tzp.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
79711
MGIiMGI:1923001 Ipo4

Phylogenomic databases

eggNOGiENOG410KD6C Eukaryota
ENOG410XP2Z LUCA
GeneTreeiENSGT00550000075074
HOGENOMiHOG000008166
HOVERGENiHBG049052
InParanoidiQ8VI75
KOiK20221
OMAiLCKTKQG
OrthoDBiEOG091G012W
PhylomeDBiQ8VI75
TreeFamiTF323157

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Ipo4 mouse

Protein Ontology

More...
PROi
PR:Q8VI75

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000002319 Expressed in 290 organ(s), highest expression level in internal carotid artery
CleanExiMM_IPO4
ExpressionAtlasiQ8VI75 baseline and differential
GenevisibleiQ8VI75 MM

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR000357 HEAT
IPR001494 Importin-beta_N
PfamiView protein in Pfam
PF02985 HEAT, 1 hit
PF03810 IBN_N, 1 hit
SMARTiView protein in SMART
SM00913 IBN_N, 1 hit
SUPFAMiSSF48371 SSF48371, 2 hits
PROSITEiView protein in PROSITE
PS50166 IMPORTIN_B_NT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIPO4_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8VI75
Secondary accession number(s): Q3TBW0, Q99J52
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 2, 2004
Last sequence update: March 1, 2002
Last modified: November 7, 2018
This is version 130 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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