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Protein

Pecanex-like protein 3

Gene

Pcnx3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Pecanex-like protein 3
Alternative name(s):
Pecanex homolog protein 3Imported
Gene namesi
Name:Pcnx3Imported
Synonyms:Pcnxl3
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:1861733 Pcnx3

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei33 – 53HelicalSequence analysisAdd BLAST21
Transmembranei54 – 74HelicalSequence analysisAdd BLAST21
Transmembranei793 – 815HelicalSequence analysisAdd BLAST23
Transmembranei819 – 836HelicalSequence analysisAdd BLAST18
Transmembranei852 – 872HelicalSequence analysisAdd BLAST21
Transmembranei880 – 900HelicalSequence analysisAdd BLAST21
Transmembranei903 – 923HelicalSequence analysisAdd BLAST21
Transmembranei946 – 968HelicalSequence analysisAdd BLAST23
Transmembranei980 – 1000HelicalSequence analysisAdd BLAST21
Transmembranei1053 – 1073HelicalSequence analysisAdd BLAST21
Transmembranei1078 – 1098HelicalSequence analysisAdd BLAST21
Transmembranei1244 – 1264HelicalSequence analysisAdd BLAST21
Transmembranei1280 – 1300HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002157961 – 2028Pecanex-like protein 3Add BLAST2028

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi95N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei127PhosphoserineCombined sources1
Modified residuei129PhosphothreonineBy similarity1
Glycosylationi319N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei370PhosphothreonineBy similarity1
Modified residuei392PhosphoserineBy similarity1
Modified residuei431PhosphoserineCombined sources1
Modified residuei505PhosphoserineCombined sources1
Modified residuei521PhosphoserineCombined sources1
Modified residuei1025PhosphoserineBy similarity1
Modified residuei1697PhosphoserineBy similarity1
Glycosylationi1770N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei1909PhosphoserineBy similarity1
Modified residuei1955PhosphoserineBy similarity1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiQ8VI59
PeptideAtlasiQ8VI59
PRIDEiQ8VI59

PTM databases

iPTMnetiQ8VI59
PhosphoSitePlusiQ8VI59
SwissPalmiQ8VI59

Expressioni

Gene expression databases

BgeeiENSMUSG00000054874 Expressed in 261 organ(s), highest expression level in cerebellum
CleanExiMM_PCNXL3
ExpressionAtlasiQ8VI59 baseline and differential
GenevisibleiQ8VI59 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000109245

Structurei

3D structure databases

ProteinModelPortaliQ8VI59
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi425 – 458Ser-richAdd BLAST34
Compositional biasi809 – 812Poly-Leu4
Compositional biasi1427 – 1430Poly-Cys4
Compositional biasi1841 – 1845Poly-Gly5
Compositional biasi1853 – 1924Pro-richAdd BLAST72

Sequence similaritiesi

Belongs to the pecanex family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3604 Eukaryota
ENOG410XPRI LUCA
GeneTreeiENSGT00390000013164
HOGENOMiHOG000007773
HOVERGENiHBG045627
InParanoidiQ8VI59
OMAiMRQSVRE
OrthoDBiEOG091G007W
PhylomeDBiQ8VI59
TreeFamiTF313570

Family and domain databases

InterProiView protein in InterPro
IPR007735 Pecanex
PfamiView protein in Pfam
PF05041 Pecanex_C, 1 hit

Sequences (2+)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.iShow all

Isoform 1 (identifier: Q8VI59-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGSQVLQILR QGVWASLTGG WFFDPHQSTF SNCFHLYVWI FLLIFPFLLY
60 70 80 90 100
MVLPPSLMVA GVYCLVVAVI FATIKTVNYR LHAMFDQGEI VEKRNSTMGE
110 120 130 140 150
QEEEAAQGES SLPRDPGVEM TVFRKVSSTP PVRCSSQHSV FGFNQVSELL
160 170 180 190 200
PRMEDSGPLR DIKELVREQG SNNVIVTSAD REMLKLSSQE KLIGDLPQTP
210 220 230 240 250
PGVVPDPSLP STDSSERSPM AGDGVPWGGS GVADTPMSPL LKGSLSQELS
260 270 280 290 300
KSFLTLTRPD RALVRTSSRR EQCRGTGGYQ PLDRRGSGDP MPQKAGSSDS
310 320 330 340 350
CFSGTDRETL SSFKSEKTNS THLDSPPGGH APEGSDTDPP SEAELPASPD
360 370 380 390 400
AGVPSDDTLR SFDTVIGAGT PPGQTEPLLV VRPKDLALLR PSKRRPPMRG
410 420 430 440 450
HSPPGRTPRR PLLEGSGFFE DEDTSEGSEL SPASSLRSQR RYSTDSSSST
460 470 480 490 500
SCYSPESSQG AAGGPRKRRA PHGAEEGTAV PPKRPYGTQR TPSTASAKTH
510 520 530 540 550
ARVLSMDGAG GDVLRAPLAG SKAELEAQPG MELAAGEPAV LPPEARRGPA
560 570 580 590 600
ANQPGWRGEL QEEGAVGGAP EETGQRECTS NVRRAQAIRR RHNAGSNPTP
610 620 630 640 650
PASVMGSPPS SLQEAQRGRA ASHSRALTLP SALHFASSLL LTRAGPNVHE
660 670 680 690 700
ASNFDDTSEG AVHYFYDESG VRRSYTFGLA GGGYENPVSQ PGEQAANGAW
710 720 730 740 750
DRHSHSSSFH SADVPEATGG LNLLQPRPVV LQGMQVRRVP LEIPEEQTLM
760 770 780 790 800
EEAPPRAQHS YKYWFLPGRW TSVRYERLAL LALLDRTRGV MENIFGVGLS
810 820 830 840 850
SLVAFLGYLL LLKGFFTDIW VFQFCLVIAS CQYSLLKSVQ PDAASPMHGH
860 870 880 890 900
NWVIAYSRPV YFCICCLLIW LLDALGTAQP FPPVSLYGLT LFSASFFFCA
910 920 930 940 950
RDVATVFTLC FPFVFLLGLL PQVNTCLMYL LEQIDMHGFG GTAATSPLTA
960 970 980 990 1000
VFSLTRSLLA AALLYGFCLG AIKTPWPEQH VPVLFSVFCG LLVAMSYHLS
1010 1020 1030 1040 1050
RQSSDPTVLW SLVRSKLFPE LEERSLETAR VEPPDPLPEK MRQSVREVLH
1060 1070 1080 1090 1100
SDLVMCVVIA VLTFAVSAST VFIALKSVLG FVLYALAGAV GFFTHYLLPQ
1110 1120 1130 1140 1150
LRKQLPWFCL SQPVLKPLEY SQYEVRGAAQ VMWFEKLYAG LQCAEKYLIY
1160 1170 1180 1190 1200
PAVVLNALTV DAHTVVSHPD KFCLYCRALL MTVAGLKLLR SAFCCPPQQY
1210 1220 1230 1240 1250
LTLAFTVLLF HFDYPRLSQG FLLDYFLMSL LCSKLWDLLY KLRFVLTYIA
1260 1270 1280 1290 1300
PWQITWGSAF HAFAQPFAVP HSAMLFLQAL LSGLFSTPLN PLLGSAVFIM
1310 1320 1330 1340 1350
SYARPLKFWE RDYNTKRVDH SNTRLVTQLD RNPGADDNNL NSIFYEHLTR
1360 1370 1380 1390 1400
SLQHTLCGDL VLGRWGNYGP GDCFVLASDY LNALVHLIEV GNGLITFQLR
1410 1420 1430 1440 1450
GLEFRGTYCQ QREVEAITEG VEEDEGCCCC EPGHLPRVLS FNAAFGQRWL
1460 1470 1480 1490 1500
AWEVTASKYV LEGYSISDNN AASMLQVFDL RKILVTYYVK SIIYYVSRSP
1510 1520 1530 1540 1550
KLETWLNHEG IAAALRPVRA LGYADSDPTF SLSVDEDYDL RLSGLSLPSF
1560 1570 1580 1590 1600
CAVHLEWIQY CASRRSQPVD QDWNSPLVTL CFGLCVLGRR ALGTASHSMS
1610 1620 1630 1640 1650
ASLEPFLYGL HALFKGDFRI TSPRDEWVFA DMDLLHRVVA PGVRMALKLH
1660 1670 1680 1690 1700
QDHFTSPDEY EEPAALYDAI AANEERLVIS HEGDPAWRSA ILSNTPSLLA
1710 1720 1730 1740 1750
LRHVMDDASD EYKIIMLNRR HLSFRVIKVN RECVRGLWAG QQQELVFLRN
1760 1770 1780 1790 1800
RNPERGSIQN AKQALRNMIN SSCDQPLGYP IYVSPLTTSL AGSHPQLRAL
1810 1820 1830 1840 1850
WGGPVSLGAI ARWLLRSWER LHKGCGAGCN SGGNVDDSDC GGGGGLTSLS
1860 1870 1880 1890 1900
NHPPLAHPTP ENAAGSSEQP LPPGPSWGPR PSLSGSGDGR PPPLLQWPPP
1910 1920 1930 1940 1950
RLPGPPPASP APTEGPRPSR PSGPALLNSE GPSGKWSLGG RKGLGGPDGE
1960 1970 1980 1990 2000
PASGSPKGGT PKSQAPLDLS LSPDVSSEAS PARTTQDLPC LDSSIPEGCT
2010 2020
PSGAPGDWPV PAEERESPAA QPLLEHQY
Length:2,028
Mass (Da):221,573
Last modified:April 29, 2008 - v2
Checksum:iB51969382FBFCA89
GO
Isoform 2 (identifier: Q8VI59-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     161-568: Missing.

Show »
Length:1,620
Mass (Da):178,898
Checksum:i01524ACED13B43F6
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6SDA4F6SDA4_MOUSE
Pecanex-like protein 3
Pcnx3 Pcnxl3
280Annotation score:
F7DCB1F7DCB1_MOUSE
Pecanex-like protein 3
Pcnx3 Pcnxl3
712Annotation score:
F7AXS1F7AXS1_MOUSE
Pecanex-like protein 3
Pcnx3 Pcnxl3
254Annotation score:
F6VNK1F6VNK1_MOUSE
Pecanex-like protein 3
Pcnx3 Pcnxl3
240Annotation score:
F6VP43F6VP43_MOUSE
Pecanex-like protein 3
Pcnx3 Pcnxl3
129Annotation score:

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_033246161 – 568Missing in isoform 2. 1 PublicationAdd BLAST408

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC096538 mRNA No translation available.
AF237953 mRNA Translation: AAL62024.1
CCDSiCCDS29475.2 [Q8VI59-1]
RefSeqiNP_659117.2, NM_144868.3 [Q8VI59-1]
UniGeneiMm.329650

Genome annotation databases

EnsembliENSMUST00000068169; ENSMUSP00000063786; ENSMUSG00000054874 [Q8VI59-2]
ENSMUST00000113615; ENSMUSP00000109245; ENSMUSG00000054874 [Q8VI59-1]
GeneIDi104401
KEGGimmu:104401
UCSCiuc008gep.2 mouse [Q8VI59-2]
uc008geq.2 mouse [Q8VI59-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiPCX3_MOUSE
AccessioniPrimary (citable) accession number: Q8VI59
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2003
Last sequence update: April 29, 2008
Last modified: September 12, 2018
This is version 99 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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