UniProtKB - Q8VHR5 (P66B_MOUSE)

BLAST

>sp|Q8VHR5|P66B_MOUSE Transcriptional repressor p66-beta OS=Mus musculus OX=10090 GN=Gatad2b PE=1 SV=1
MDRMTEDALRLNLLKRSLDPADERDDVLAKRLKMEGHEAMERLKMLALLKRKDLANLEVP
HELPTKQDGSGVKGYEEKLNGNLRPHGDNNRTAGRPGKENINDEPVDMSARRSEPDRGRL
TPSPDIIVLSDNEASSPRSSSRMEERLKAANLEMFKGKGMEERQQLIKQLRDELRLEEAR
LVLLKKLRQSQLQKENVVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQGIEPQNM
RTLQGHSVIRSATNTTLPHMLMSQRVIAPNPAQLQGQRGPPKPGIVRTTTPNMNPAISYQ
PQSSSSVPCQRTTSSAIYMNLASHIQPGTVNRVSSPLPSPSAMSDAANSQAAAKLALRKQ
LEKTLLEIPPPKPPAPLLHFLPSAANSEFIYMVGLEEVVQSVIDSQGKNCASLLRVEPFV
CAQCRTDFTPHWKQEKNGKILCEQCMTSNQKKALKAEHTNRLKNAFVKALQQEQEIEQRL
QQQAALSPTTAPAVSSVSKQETIMRHHTLRQAPQPQSSLQRGIPTSARSMLSNFAQAPQL
SVPGGLLGMPGVNIAYLNTGIGGHKAPSLADRQREYLLDMIPPRSISQSISGQK

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History
Entry version 134 (07 Nov 2018)
Sequence version 1 (01 Mar 2002)
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Protein

Transcriptional repressor p66-beta

Gene

Gatad2b

Organism

Mus musculus (Mouse)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2A (By similarity). Targets MBD3 to discrete loci in the nucleus (By similarity). Plays a role in synapse development (By similarity).By similarity

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	415 – 468	GATA-typePROSITE-ProRule annotationAdd BLAST		54

GO - Molecular functionⁱ

sequence-specific DNA binding Source: InterPro
zinc ion binding Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

negative regulation of transcription by RNA polymerase II
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Repressor
Biological process	Transcription, Transcription regulation
Ligand	Metal-binding, Zinc

Enzyme and pathway databases

Reactomeⁱ	R-MMU-3214815 HDACs deacetylate histones R-MMU-6804758 Regulation of TP53 Activity through Acetylation R-MMU-73762 RNA Polymerase I Transcription Initiation R-MMU-8943724 Regulation of PTEN gene transcription

Reactomeⁱ

R-MMU-3214815 HDACs deacetylate histones
R-MMU-6804758 Regulation of TP53 Activity through Acetylation
R-MMU-73762 RNA Polymerase I Transcription Initiation
R-MMU-8943724 Regulation of PTEN gene transcription

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Transcriptional repressor p66-beta Alternative name(s): GATA zinc finger domain-containing protein 2B p66/p68
Gene namesⁱ	Name:Gatad2b
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 3

Organism-specific databases

MGIⁱ	MGI:2443225 Gatad2b

Keywords - Cellular componentⁱ

Nucleus

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000083503	1 – 594	Transcriptional repressor p66-betaAdd BLAST		594

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	17	PhosphoserineBy similarity	1
Cross-linkⁱ	33	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linkⁱ	66	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linkⁱ	98	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residueⁱ	121	PhosphothreonineCombined sources	1
Modified residueⁱ	123	PhosphoserineCombined sources	1
Modified residueⁱ	130	PhosphoserineCombined sources	1
Modified residueⁱ	135	PhosphoserineCombined sources	1
Modified residueⁱ	136	PhosphoserineCombined sources	1
Cross-linkⁱ	148	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linkⁱ	200	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residueⁱ	209	PhosphoserineBy similarity	1
Cross-linkⁱ	282	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residueⁱ	334	PhosphoserineBy similarity	1
Modified residueⁱ	339	PhosphoserineCombined sources	1
Modified residueⁱ	341	PhosphoserineCombined sources	1
Cross-linkⁱ	354	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linkⁱ	455	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linkⁱ	468	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residueⁱ	487	PhosphoserineBy similarity	1
Cross-linkⁱ	499	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMⁱ

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDⁱ	Q8VHR5
PaxDbⁱ	Q8VHR5
PeptideAtlas More...PeptideAtlasⁱ	Q8VHR5
PRIDEⁱ	Q8VHR5

PTM databases

iPTMnetⁱ	Q8VHR5
PhosphoSitePlusⁱ	Q8VHR5

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000042390 Expressed in 255 organ(s), highest expression level in secondary oocyte
CleanExⁱ	MM_GATAD2B
ExpressionAtlasⁱ	Q8VHR5 baseline and differential
Genevisibleⁱ	Q8VHR5 MM

Interactionⁱ

Subunit structureⁱ

Binds MBD2 and MBD3. Interaction with MBD2 is required for the enhancement of MBD2-mediated repression and for targeting to the chromatin (By similarity). Component of the MeCP1 histone deacetylase complex (By similarity). Interacts with histone tails, including that of histones H2A, H2B, H3 and H4 (By similarity).By similarity

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
Nr4a1	P12813	2	EBI-3043880,EBI-10896863

With

Entry

#Exp.

IntAct

Notes

Nr4a1

P12813

EBI-3043880,EBI-10896863

Protein-protein interaction databases

BioGridⁱ	230858, 9 interactors
ComplexPortalⁱ	CPX-953 MBD2/NuRD nucleosome remodeling and deacetylase complex CPX-954 MBD3/NuRD nucleosome remodeling and deacetylase complex
CORUMⁱ	Q8VHR5
Database of interacting proteins More...DIPⁱ	DIP-62049N
IntActⁱ	Q8VHR5, 8 interactors
Molecular INTeraction database More...MINTⁱ	Q8VHR5
STRINGⁱ	10090.ENSMUSP00000041370

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q8VHR5
SMRⁱ	Q8VHR5
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	166 – 191	CR1Add BLAST		26
Regionⁱ	341 – 481	CR2Add BLAST		141

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	141 – 195	Sequence analysisAdd BLAST		55
Coiled coilⁱ	450 – 483	Sequence analysisAdd BLAST		34

Domainⁱ

Both CR1 and CR2 regions are required for speckled nuclear localization.By similarity

Zinc finger

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	415 – 468	GATA-typePROSITE-ProRule annotationAdd BLAST		54

Keywords - Domainⁱ

Coiled coil, Zinc-finger

Phylogenomic databases

eggNOGⁱ	ENOG410IQ4W Eukaryota ENOG410ZCNE LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000004097
HOGENOMⁱ	HOG000074070
HOVERGENⁱ	HBG053401
InParanoidⁱ	Q8VHR5
OMAⁱ	MNPTINY
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0HRN
PhylomeDBⁱ	Q8VHR5
TreeFamⁱ	TF321369

Family and domain databases

Gene3Dⁱ	3.30.50.10, 1 hit
InterProⁱ	View protein in InterPro IPR032346 P66_CC IPR000679 Znf_GATA IPR013088 Znf_NHR/GATA
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00320 GATA, 1 hit PF16563 P66_CC, 1 hit
PROSITEⁱ	View protein in PROSITE PS50114 GATA_ZN_FINGER_2, 1 hit

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q8VHR5-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MDRMTEDALR LNLLKRSLDP ADERDDVLAK RLKMEGHEAM ERLKMLALLK 
        60         70         80         90        100
RKDLANLEVP HELPTKQDGS GVKGYEEKLN GNLRPHGDNN RTAGRPGKEN 
       110        120        130        140        150
INDEPVDMSA RRSEPDRGRL TPSPDIIVLS DNEASSPRSS SRMEERLKAA 
       160        170        180        190        200
NLEMFKGKGM EERQQLIKQL RDELRLEEAR LVLLKKLRQS QLQKENVVQK 
       210        220        230        240        250
TPVVQNAASI VQPSPAHVGQ QGLSKLPSRP GAQGIEPQNM RTLQGHSVIR 
       260        270        280        290        300
SATNTTLPHM LMSQRVIAPN PAQLQGQRGP PKPGIVRTTT PNMNPAISYQ 
       310        320        330        340        350
PQSSSSVPCQ RTTSSAIYMN LASHIQPGTV NRVSSPLPSP SAMSDAANSQ 
       360        370        380        390        400
AAAKLALRKQ LEKTLLEIPP PKPPAPLLHF LPSAANSEFI YMVGLEEVVQ 
       410        420        430        440        450
SVIDSQGKNC ASLLRVEPFV CAQCRTDFTP HWKQEKNGKI LCEQCMTSNQ 
       460        470        480        490        500
KKALKAEHTN RLKNAFVKAL QQEQEIEQRL QQQAALSPTT APAVSSVSKQ 
       510        520        530        540        550
ETIMRHHTLR QAPQPQSSLQ RGIPTSARSM LSNFAQAPQL SVPGGLLGMP 
       560        570        580        590 
GVNIAYLNTG IGGHKAPSLA DRQREYLLDM IPPRSISQSI SGQK

Length:594

Mass (Da):65,411

Last modified:March 1, 2002 - v1

Checksum:ⁱC57330259EADAAE6

Isoform 2 (identifier: Q8VHR5-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
475-485: EIEQRLQQQAA → VRTLTPTCTVI
486-594: Missing.

« Hide

        10         20         30         40         50
MDRMTEDALR LNLLKRSLDP ADERDDVLAK RLKMEGHEAM ERLKMLALLK 
        60         70         80         90        100
RKDLANLEVP HELPTKQDGS GVKGYEEKLN GNLRPHGDNN RTAGRPGKEN 
       110        120        130        140        150
INDEPVDMSA RRSEPDRGRL TPSPDIIVLS DNEASSPRSS SRMEERLKAA 
       160        170        180        190        200
NLEMFKGKGM EERQQLIKQL RDELRLEEAR LVLLKKLRQS QLQKENVVQK 
       210        220        230        240        250
TPVVQNAASI VQPSPAHVGQ QGLSKLPSRP GAQGIEPQNM RTLQGHSVIR 
       260        270        280        290        300
SATNTTLPHM LMSQRVIAPN PAQLQGQRGP PKPGIVRTTT PNMNPAISYQ 
       310        320        330        340        350
PQSSSSVPCQ RTTSSAIYMN LASHIQPGTV NRVSSPLPSP SAMSDAANSQ 
       360        370        380        390        400
AAAKLALRKQ LEKTLLEIPP PKPPAPLLHF LPSAANSEFI YMVGLEEVVQ 
       410        420        430        440        450
SVIDSQGKNC ASLLRVEPFV CAQCRTDFTP HWKQEKNGKI LCEQCMTSNQ 
       460        470        480 
KKALKAEHTN RLKNAFVKAL QQEQVRTLTP TCTVI

Note: May be due to intron retention. No experimental confirmation available.

Show »

Length:485

Mass (Da):53,734

Checksum:ⁱ319D9E907558D734

Computationally mapped potential isoform sequencesⁱ

There are 2 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

A1L3S7	A1L3S7_MOUSE	Gatad2b protein Gatad2b protein (Transcriptional repressor p66-beta)	Gatad2b	578	Annotation score:
A0A0U1RNM2	A0A0U1RNM2_MOUSE	Transcriptional repressor p66-beta Transcriptional repressor p66-beta	Gatad2b	263	Annotation score:

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_010930	475 – 485	EIEQRLQQQAA → VRTLTPTCTVI in isoform 2. 1 PublicationAdd BLAST		11
Alternative sequenceⁱVSP_010931	486 – 594	Missing in isoform 2. 1 PublicationAdd BLAST		109

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF411837 mRNA Translation: AAL39081.1 AK041594 mRNA Translation: BAC30997.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS17526.1 [Q8VHR5-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_647465.1, NM_139304.1 [Q8VHR5-1] XP_006501422.2, XM_006501359.3 [Q8VHR5-1] XP_006501424.1, XM_006501361.2 [Q8VHR5-1]
UniGeneⁱ	Mm.270999

Genome annotation databases

Ensemblⁱ	ENSMUST00000049382; ENSMUSP00000041370; ENSMUSG00000042390 [Q8VHR5-1] ENSMUST00000199607; ENSMUSP00000142617; ENSMUSG00000042390 [Q8VHR5-1] ENSMUST00000199754; ENSMUSP00000142514; ENSMUSG00000042390 [Q8VHR5-1]
GeneIDⁱ	229542
KEGGⁱ	mmu:229542
UCSC genome browser More...UCSCⁱ	uc008qca.1 mouse [Q8VHR5-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q8VHR5	MKIAA1150 protein (Fragment)		MOUSE		369	UniRef100_Q8VHR5

Protein	Similar proteins		Species	Score	Length	Source
Q8VHR5	MKIAA1150 protein (Fragment)		MOUSE		369	UniRef90_Q8VHR5
GATAD2B isoform 1		PONAB		705
GATA zinc finger domain containing 2B		CALJA		604
GATA zinc finger domain containing 2B		SAIBB		601
GATAD2B isoform 3		PANTR		600
+139

Protein	Similar proteins		Species	Score	Length	Source
Q8VHR5	Transcriptional repressor p66-beta		HUMAN		593	UniRef50_Q8WXI9
GATA zinc finger domain containing 2B		MACMU		593
Transcriptional repressor p66-beta		CALJA		593
GATAD2B isoform 2		PONAB		593
Uncharacterized protein		COLAP		593
+265

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF411837 mRNA Translation: AAL39081.1 AK041594 mRNA Translation: BAC30997.1
CCDSⁱ	CCDS17526.1 [Q8VHR5-1]
RefSeqⁱ	NP_647465.1, NM_139304.1 [Q8VHR5-1] XP_006501422.2, XM_006501359.3 [Q8VHR5-1] XP_006501424.1, XM_006501361.2 [Q8VHR5-1]
UniGeneⁱ	Mm.270999

3D structure databases

ProteinModelPortalⁱ	Q8VHR5
SMRⁱ	Q8VHR5
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	230858, 9 interactors
ComplexPortalⁱ	CPX-953 MBD2/NuRD nucleosome remodeling and deacetylase complex CPX-954 MBD3/NuRD nucleosome remodeling and deacetylase complex
CORUMⁱ	Q8VHR5
DIPⁱ	DIP-62049N
IntActⁱ	Q8VHR5, 8 interactors
MINTⁱ	Q8VHR5
STRINGⁱ	10090.ENSMUSP00000041370

PTM databases

iPTMnetⁱ	Q8VHR5
PhosphoSitePlusⁱ	Q8VHR5

Proteomic databases

EPDⁱ	Q8VHR5
PaxDbⁱ	Q8VHR5
PeptideAtlasⁱ	Q8VHR5
PRIDEⁱ	Q8VHR5

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000049382; ENSMUSP00000041370; ENSMUSG00000042390 [Q8VHR5-1] ENSMUST00000199607; ENSMUSP00000142617; ENSMUSG00000042390 [Q8VHR5-1] ENSMUST00000199754; ENSMUSP00000142514; ENSMUSG00000042390 [Q8VHR5-1]
GeneIDⁱ	229542
KEGGⁱ	mmu:229542
UCSCⁱ	uc008qca.1 mouse [Q8VHR5-1]

Organism-specific databases

CTDⁱ	57459
MGIⁱ	MGI:2443225 Gatad2b

Phylogenomic databases

eggNOGⁱ	ENOG410IQ4W Eukaryota ENOG410ZCNE LUCA
GeneTreeⁱ	ENSGT00390000004097
HOGENOMⁱ	HOG000074070
HOVERGENⁱ	HBG053401
InParanoidⁱ	Q8VHR5
OMAⁱ	MNPTINY
OrthoDBⁱ	EOG091G0HRN
PhylomeDBⁱ	Q8VHR5
TreeFamⁱ	TF321369

Enzyme and pathway databases

Reactomeⁱ	R-MMU-3214815 HDACs deacetylate histones R-MMU-6804758 Regulation of TP53 Activity through Acetylation R-MMU-73762 RNA Polymerase I Transcription Initiation R-MMU-8943724 Regulation of PTEN gene transcription

Reactomeⁱ

Miscellaneous databases

ChiTaRSⁱ	Gatad2b mouse
Protein Ontology More...PROⁱ	PR:Q8VHR5
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000042390 Expressed in 255 organ(s), highest expression level in secondary oocyte
CleanExⁱ	MM_GATAD2B
ExpressionAtlasⁱ	Q8VHR5 baseline and differential
Genevisibleⁱ	Q8VHR5 MM

Family and domain databases

Gene3Dⁱ	3.30.50.10, 1 hit
InterProⁱ	View protein in InterPro IPR032346 P66_CC IPR000679 Znf_GATA IPR013088 Znf_NHR/GATA
Pfamⁱ	View protein in Pfam PF00320 GATA, 1 hit PF16563 P66_CC, 1 hit
PROSITEⁱ	View protein in PROSITE PS50114 GATA_ZN_FINGER_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	P66B_MOUSE
Accessionⁱ	Q8VHR5Primary (citable) accession number: Q8VHR5 Secondary accession number(s): Q8C9Q3
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 19, 2004
	Last sequence update:	March 1, 2002
	Last modified:	November 7, 2018
	This is version 134 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q8VHR5 (P66B_MOUSE)

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Transcriptional repressor p66-beta

Gatad2b

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Coiled coil

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ