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Protein

Olfactory receptor

Gene

Olfr272

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer
Biological processOlfactionUniRule annotationSAAS annotation, Sensory transduction

Enzyme and pathway databases

ReactomeiR-MMU-381753 Olfactory Signaling Pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptorUniRule annotation
Gene namesi
Name:Olfr272Imported
ORF Names:mCG_56267Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:3030106 Olfr272

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei26 – 50HelicalUniRule annotationAdd BLAST25
Transmembranei62 – 86HelicalUniRule annotationAdd BLAST25
Transmembranei98 – 120HelicalUniRule annotationAdd BLAST23
Transmembranei141 – 158HelicalUniRule annotationAdd BLAST18
Transmembranei204 – 226HelicalUniRule annotationAdd BLAST23
Transmembranei238 – 259HelicalUniRule annotationAdd BLAST22
Transmembranei279 – 298HelicalUniRule annotationAdd BLAST20

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000051593 Expressed in 2 organ(s), highest expression level in olfactory epithelium

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000055721

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 296G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST256

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410J9DN Eukaryota
ENOG41115KZ LUCA
GeneTreeiENSGT00760000119058
HOGENOMiHOG000041364
HOG000041365
HOVERGENiHBG017625
KOiK04257
OMAiWVTGLVD
OrthoDBiEOG091G0CU6
TreeFamiTF352686

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8VGA0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEMTNDSMLT EFLLVGLSDH PKLQTVLFVL VLCMYLMILL GNGVLIAVVI
60 70 80 90 100
HDIRLHTPMY FFLCNLSFLD ICYTSSSVPL ILSSFLTVRK RVSFSECMIQ
110 120 130 140 150
MFFSFAMGAT ECVLLGTMAL DRFMAICYPL RYPVIMSKDT YVPMAAGCWV
160 170 180 190 200
AGLVDSVVQT SLAVQLPFCT NNVIHHFVCE ILGILELACA DISINVISLT
210 220 230 240 250
GSNLLFLAVP LLVIAVSYMF IIATILRIPS AEGKRKAFST CSAHLTVVII
260 270 280 290 300
FYGTIFSMYA KPKSKDTAGA GHQSVMEALI SLFYGVMTPM LNPLIYSLRN
310
KDVKAAVQNM LGRKTLSKM
Length:319
Mass (Da):35,261
Last modified:March 1, 2002 - v1
Checksum:i6758589AA782017F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL772397 Genomic DNA No translation available.
BC128006 mRNA Translation: AAI28007.1
AY073254 Genomic DNA Translation: AAL60917.1
AY317365 Genomic DNA Translation: AAP70824.1
CH466565 Genomic DNA Translation: EDL02292.1
RefSeqiNP_667050.1, NM_146839.1
UniGeneiMm.331617

Genome annotation databases

EnsembliENSMUST00000051600; ENSMUSP00000055721; ENSMUSG00000051593
ENSMUST00000107667; ENSMUSP00000103294; ENSMUSG00000051593
ENSMUST00000213989; ENSMUSP00000149339; ENSMUSG00000051593
GeneIDi258836
KEGGimmu:258836
UCSCiuc008swq.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL772397 Genomic DNA No translation available.
BC128006 mRNA Translation: AAI28007.1
AY073254 Genomic DNA Translation: AAL60917.1
AY317365 Genomic DNA Translation: AAP70824.1
CH466565 Genomic DNA Translation: EDL02292.1
RefSeqiNP_667050.1, NM_146839.1
UniGeneiMm.331617

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000055721

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000051600; ENSMUSP00000055721; ENSMUSG00000051593
ENSMUST00000107667; ENSMUSP00000103294; ENSMUSG00000051593
ENSMUST00000213989; ENSMUSP00000149339; ENSMUSG00000051593
GeneIDi258836
KEGGimmu:258836
UCSCiuc008swq.1 mouse

Organism-specific databases

CTDi258836
MGIiMGI:3030106 Olfr272

Phylogenomic databases

eggNOGiENOG410J9DN Eukaryota
ENOG41115KZ LUCA
GeneTreeiENSGT00760000119058
HOGENOMiHOG000041364
HOG000041365
HOVERGENiHBG017625
KOiK04257
OMAiWVTGLVD
OrthoDBiEOG091G0CU6
TreeFamiTF352686

Enzyme and pathway databases

ReactomeiR-MMU-381753 Olfactory Signaling Pathway

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000051593 Expressed in 2 organ(s), highest expression level in olfactory epithelium

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ8VGA0_MOUSE
AccessioniPrimary (citable) accession number: Q8VGA0
Secondary accession number(s): B1AWZ7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: November 7, 2018
This is version 135 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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