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Protein

Protein FAM114A2

Gene

Fam114a2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM114A2
Gene namesi
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1917629 Fam114a2

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002745651 – 497Protein FAM114A2Add BLAST497

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei84PhosphoserineBy similarity1
Modified residuei205PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ8VE88
PeptideAtlasiQ8VE88
PRIDEiQ8VE88

PTM databases

iPTMnetiQ8VE88
PhosphoSitePlusiQ8VE88
SwissPalmiQ8VE88

Expressioni

Gene expression databases

BgeeiENSMUSG00000020523 Expressed in 301 organ(s), highest expression level in seminal vesicle
GenevisibleiQ8VE88 MM

Interactioni

Protein-protein interaction databases

IntActiQ8VE88, 1 interactor
MINTiQ8VE88

Structurei

3D structure databases

ProteinModelPortaliQ8VE88
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi293 – 298Poly-Glu6

Sequence similaritiesi

Belongs to the FAM114 family.Curated

Phylogenomic databases

eggNOGiENOG410IHQB Eukaryota
ENOG411029H LUCA
GeneTreeiENSGT00390000010054
HOGENOMiHOG000059573
HOVERGENiHBG056879
InParanoidiQ8VE88
OMAiLFENYCG
OrthoDBiEOG091G06FS
PhylomeDBiQ8VE88
TreeFamiTF324360

Family and domain databases

InterProiView protein in InterPro
IPR007998 DUF719
PANTHERiPTHR12842 PTHR12842, 1 hit
PfamiView protein in Pfam
PF05334 DUF719, 1 hit

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q8VE88-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSDKDPPESP VVTGVASTLK DENCEPVEKP EDKSQPVVST RKRPETKPSS
60 70 80 90 100
DLEASALPAQ VSLAVAKETA SKDVPQTGWG YWGSWGKSLL SSASATVATV
110 120 130 140 150
GQGISNVIEK AETSLGIPSP TEISAEVKQA AGEKNAGENG SLLVAAPFGM
160 170 180 190 200
LSTISTAVQS TGKSVISGGL DALEFIGKKT MDVIAEGDPG FKRTKGLMNR
210 220 230 240 250
TSTLSQVLRE AKDKEEQRPS NEVTMETDKK THYGLLFDEF QGLSHLEALE
260 270 280 290 300
MLSRESEIKV KSILSSLSGE ELQTTRLELE QLKEVFSLAE FCEEEEEERQ
310 320 330 340 350
GDDNFTKEIT DLFAQLHVSS RPEKLARARN TAYKWIRTSL ARPVAEKEEG
360 370 380 390 400
EKESEAGNTE EAQKHSIEDI HAFAIRSLAE LTACSIELFH KTAALVLHGQ
410 420 430 440 450
KQEVTALERS QTLSQMTVML CKDLASLSKE FTTCLTTAGV REKADVLNPV
460 470 480 490
ITAVFLEASN SASYIQDAFQ LLLPVLQISL IESKTESSTC EPQSRDL
Length:497
Mass (Da):54,045
Last modified:February 6, 2007 - v2
Checksum:i9346964631460F6D
GO
Isoform 2 (identifier: Q8VE88-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     61-67: Missing.

Show »
Length:490
Mass (Da):53,376
Checksum:iEFD0D0464955F95E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti14G → E in AAH19518 (PubMed:15489334).Curated1
Sequence conflicti304N → D in AAH19518 (PubMed:15489334).Curated1
Sequence conflicti318V → I in AAH19518 (PubMed:15489334).Curated1
Sequence conflicti438A → V in AAH19518 (PubMed:15489334).Curated1
Sequence conflicti488S → P in BAE29069 (PubMed:16141072).Curated1
Sequence conflicti494S → P in AAH19518 (PubMed:15489334).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_02279661 – 67Missing in isoform 2. 1 Publication7

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK018570 mRNA Translation: BAB31282.1
AK149763 mRNA Translation: BAE29069.1
AL672236 Genomic DNA No translation available.
BC019518 mRNA Translation: AAH19518.1
CCDSiCCDS24717.1 [Q8VE88-2]
CCDS48801.1 [Q8VE88-1]
RefSeqiNP_001162138.1, NM_001168667.1 [Q8VE88-2]
NP_001162139.1, NM_001168668.1 [Q8VE88-1]
NP_080618.1, NM_026342.3 [Q8VE88-2]
XP_006534079.1, XM_006534016.3 [Q8VE88-1]
XP_011247496.1, XM_011249194.2 [Q8VE88-1]
XP_011247497.1, XM_011249195.2 [Q8VE88-2]
UniGeneiMm.25632

Genome annotation databases

EnsembliENSMUST00000020831; ENSMUSP00000020831; ENSMUSG00000020523 [Q8VE88-2]
ENSMUST00000108850; ENSMUSP00000104478; ENSMUSG00000020523 [Q8VE88-1]
GeneIDi67726
KEGGimmu:67726
UCSCiuc007izt.2 mouse [Q8VE88-1]
uc007izu.2 mouse [Q8VE88-2]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK018570 mRNA Translation: BAB31282.1
AK149763 mRNA Translation: BAE29069.1
AL672236 Genomic DNA No translation available.
BC019518 mRNA Translation: AAH19518.1
CCDSiCCDS24717.1 [Q8VE88-2]
CCDS48801.1 [Q8VE88-1]
RefSeqiNP_001162138.1, NM_001168667.1 [Q8VE88-2]
NP_001162139.1, NM_001168668.1 [Q8VE88-1]
NP_080618.1, NM_026342.3 [Q8VE88-2]
XP_006534079.1, XM_006534016.3 [Q8VE88-1]
XP_011247496.1, XM_011249194.2 [Q8VE88-1]
XP_011247497.1, XM_011249195.2 [Q8VE88-2]
UniGeneiMm.25632

3D structure databases

ProteinModelPortaliQ8VE88
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8VE88, 1 interactor
MINTiQ8VE88

PTM databases

iPTMnetiQ8VE88
PhosphoSitePlusiQ8VE88
SwissPalmiQ8VE88

Proteomic databases

PaxDbiQ8VE88
PeptideAtlasiQ8VE88
PRIDEiQ8VE88

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000020831; ENSMUSP00000020831; ENSMUSG00000020523 [Q8VE88-2]
ENSMUST00000108850; ENSMUSP00000104478; ENSMUSG00000020523 [Q8VE88-1]
GeneIDi67726
KEGGimmu:67726
UCSCiuc007izt.2 mouse [Q8VE88-1]
uc007izu.2 mouse [Q8VE88-2]

Organism-specific databases

CTDi10827
MGIiMGI:1917629 Fam114a2

Phylogenomic databases

eggNOGiENOG410IHQB Eukaryota
ENOG411029H LUCA
GeneTreeiENSGT00390000010054
HOGENOMiHOG000059573
HOVERGENiHBG056879
InParanoidiQ8VE88
OMAiLFENYCG
OrthoDBiEOG091G06FS
PhylomeDBiQ8VE88
TreeFamiTF324360

Miscellaneous databases

PROiPR:Q8VE88
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000020523 Expressed in 301 organ(s), highest expression level in seminal vesicle
GenevisibleiQ8VE88 MM

Family and domain databases

InterProiView protein in InterPro
IPR007998 DUF719
PANTHERiPTHR12842 PTHR12842, 1 hit
PfamiView protein in Pfam
PF05334 DUF719, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF1142_MOUSE
AccessioniPrimary (citable) accession number: Q8VE88
Secondary accession number(s): Q3UE42, Q5QNR1, Q9D310
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: February 6, 2007
Last modified: November 7, 2018
This is version 97 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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