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Protein

Ganglioside-induced differentiation-associated protein 1-like 1

Gene

Gdap1l1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

While belonging to the GST superfamily, it probably lacks glutathione transferase activity.Curated

Names & Taxonomyi

Protein namesi
Recommended name:
Ganglioside-induced differentiation-associated protein 1-like 1
Short name:
GDAP1-L1
Gene namesi
Name:Gdap1l1
Synonyms:Gdap1l
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:2385163 Gdap1l1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001860411 – 370Ganglioside-induced differentiation-associated protein 1-like 1Add BLAST370

Proteomic databases

MaxQBiQ8VE33
PaxDbiQ8VE33
PRIDEiQ8VE33

PTM databases

iPTMnetiQ8VE33
PhosphoSitePlusiQ8VE33
SwissPalmiQ8VE33

Expressioni

Gene expression databases

BgeeiENSMUSG00000017943 Expressed in 131 organ(s), highest expression level in brain
ExpressionAtlasiQ8VE33 baseline and differential
GenevisibleiQ8VE33 MM

Interactioni

Protein-protein interaction databases

IntActiQ8VE33, 2 interactors
MINTiQ8VE33
STRINGi10090.ENSMUSP00000018087

Structurei

3D structure databases

ProteinModelPortaliQ8VE33
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 129GST N-terminalAdd BLAST85
Domaini177 – 344GST C-terminalAdd BLAST168

Sequence similaritiesi

Belongs to the GST superfamily.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG4420 Eukaryota
ENOG410YE2J LUCA
GeneTreeiENSGT00510000046788
HOGENOMiHOG000231002
HOVERGENiHBG051717
InParanoidiQ8VE33
OrthoDBiEOG091G0BAC
PhylomeDBiQ8VE33

Family and domain databases

InterProiView protein in InterPro
IPR034336 GDAP1
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR036249 Thioredoxin-like_sf
PANTHERiPTHR44188 PTHR44188, 1 hit
PfamiView protein in Pfam
PF13417 GST_N_3, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q8VE33-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATPNNLTPT NCSWWPISAL ESDAAKPVET PDAPEASSPA HWPKESLVLY
60 70 80 90 100
HWTQSFSSQK RLQVRLVIAE KGLACEERDV SLPQSEHKEP WFMRLNLGEE
110 120 130 140 150
VPVIIHRDNI ISDYDQIIDY VERTFTGEHV VALMPEAGSP QHARVLQYRE
160 170 180 190 200
LLDALPMDAY THGCILHPEL TTDSMIPKYA TAEIRRHLAN ATTDLMKLDH
210 220 230 240 250
EEEPQLSEPY LSKQKKLMAK ILEHDDVSYL KKILGELAMV LDQIEAELEK
260 270 280 290 300
RKLENEGQTC ELWLCGCAFT LADVLLGATL HRLKFLGLSK KYWEDGSRPN
310 320 330 340 350
LQSFFERVQR RFAFRKVLGD IHTTLLSAVI PNAFRLVKRK PPSFFGASFL
360 370
MGSLGGMGYF AYWYLKKKYI
Length:370
Mass (Da):42,318
Last modified:March 1, 2002 - v1
Checksum:i7ACDD616D8A9D399
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q3USC7Q3USC7_MOUSE
Ganglioside-induced differentiation...
Gdap1l1
367Annotation score:
A2A5H8A2A5H8_MOUSE
Ganglioside-induced differentiation...
Gdap1l1
266Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591488 Genomic DNA No translation available.
BC019941 mRNA Translation: AAH19941.1
UniGeneiMm.102080

Genome annotation databases

EnsembliENSMUST00000109421; ENSMUSP00000105048; ENSMUSG00000017943
UCSCiuc012ciq.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591488 Genomic DNA No translation available.
BC019941 mRNA Translation: AAH19941.1
UniGeneiMm.102080

3D structure databases

ProteinModelPortaliQ8VE33
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8VE33, 2 interactors
MINTiQ8VE33
STRINGi10090.ENSMUSP00000018087

PTM databases

iPTMnetiQ8VE33
PhosphoSitePlusiQ8VE33
SwissPalmiQ8VE33

Proteomic databases

MaxQBiQ8VE33
PaxDbiQ8VE33
PRIDEiQ8VE33

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000109421; ENSMUSP00000105048; ENSMUSG00000017943
UCSCiuc012ciq.1 mouse

Organism-specific databases

MGIiMGI:2385163 Gdap1l1

Phylogenomic databases

eggNOGiKOG4420 Eukaryota
ENOG410YE2J LUCA
GeneTreeiENSGT00510000046788
HOGENOMiHOG000231002
HOVERGENiHBG051717
InParanoidiQ8VE33
OrthoDBiEOG091G0BAC
PhylomeDBiQ8VE33

Miscellaneous databases

PROiPR:Q8VE33
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000017943 Expressed in 131 organ(s), highest expression level in brain
ExpressionAtlasiQ8VE33 baseline and differential
GenevisibleiQ8VE33 MM

Family and domain databases

InterProiView protein in InterPro
IPR034336 GDAP1
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR036249 Thioredoxin-like_sf
PANTHERiPTHR44188 PTHR44188, 1 hit
PfamiView protein in Pfam
PF13417 GST_N_3, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiGD1L1_MOUSE
AccessioniPrimary (citable) accession number: Q8VE33
Secondary accession number(s): A2A5I0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 7, 2003
Last sequence update: March 1, 2002
Last modified: November 7, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health

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