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1 to 25 of 25  Show
  1. 1
    "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    Category: Sequences.
    Strain: C57BL/6J.
    Tissue: Corpora quadrigemina, Embryo, Liver and Lung.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 10645 and mapped to 44212 other entries.

  2. 2
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3).
    Category: Sequences.
    Strain: FVB/N.
    Tissue: Eye, Mammary tumor and Salivary gland.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50435 other entries.

  3. 3
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 25276 and mapped to 5 other entries.

  4. 4
    "A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter."
    De Stefani D., Raffaello A., Teardo E., Szabo I., Rizzuto R.
    Nature 476:336-340(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY.
    Category: Expression.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 and mapped to 8 other entries.

  5. 5
    "MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling."
    Plovanich M., Bogorad R.L., Sancak Y., Kamer K.J., Strittmatter L., Li A.A., Girgis H.S., Kuchimanchi S., De Groot J., Speciner L., Taneja N., Oshea J., Koteliansky V., Mootha V.K.
    PLoS ONE 8:E55785-E55785(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION IN A COMPLEX WITH MCU AND MICU2, TISSUE SPECIFICITY.
    Category: Expression, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3 and mapped to 10 other entries.

  6. 6
    "MICU1 and MICU2 finely tune the mitochondrial Ca(2+) uniporter by exerting opposite effects on MCU activity."
    Patron M., Checchetto V., Raffaello A., Teardo E., Vecellio Reane D., Mantoan M., Granatiero V., Szabo I., De Stefani D., Rizzuto R.
    Mol. Cell 53:726-737(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH MICU2, DISULFIDE BOND, CALCIUM-BINDING MUTAGENESIS OF CYS-62; CYS-203; ASP-233; GLU-244; CYS-277; ASP-423; GLU-434 AND CYS-465.
    Category: Function, Pathology & Biotech, PTM / Processing, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 4 and mapped to 6 other entries.

  7. 7
    "MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration."
    Antony A.N., Paillard M., Moffat C., Juskeviciute E., Correnti J., Bolon B., Rubin E., Csordas G., Seifert E.L., Hoek J.B., Hajnoczky G.
    Nat. Commun. 7:10955-10955(2016) [PubMed] [Europe PMC] [Abstract]
    Cited for: DISRUPTION PHENOTYPE.
    Category: Pathology & Biotech.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 1 other entry.

  8. 8
    "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    Okazaki Y., Furuno M., Kasukawa T., Adachi J., Bono H., Kondo S., Nikaido I., Osato N., Saito R., Suzuki H., Yamanaka I., Kiyosawa H., Yagi K., Tomaru Y., Hasegawa Y., Nogami A., Schonbach C., Gojobori T.
    Hayashizaki Y.
    Nature 420:563-573(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Source: MGI:2384909.

    This publication is cited by 16951 and mapped to 41689 other entries.

  9. 9
    Category: Sequences.
    Source: MGI:2384909.

    This publication is mapped to 18710 other entries.

  10. 10
    "Hom s 4, an IgE-reactive autoantigen belonging to a new subfamily of calcium-binding proteins, can induce Th cell type 1-mediated autoreactivity."
    Aichberger K.J., Mittermann I., Reininger R., Seiberler S., Swoboda I., Spitzauer S., Kopp T., Stingl G., Sperr W.R., Valent P., Repa A., Bohle B., Kraft D., Valenta R.
    J. Immunol. 175:1286-1294(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Source: MGI:2384909.

    This publication is mapped to 2 other entries.

  11. 11
    "EUCOMM--the European conditional mouse mutagenesis program."
    Friedel R.H., Seisenberger C., Kaloff C., Wurst W.
    Brief Funct Genomic Proteomic 6:180-185(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Source: MGI:2384909.

    This publication is mapped to 11055 other entries.

  12. 12
    Category: Subcellular Location.
    Source: MGI:2384909.

    This publication is cited by 9 and mapped to 3692 other entries.

  13. 13
    Category: Sequences.
    Source: MGI:2384909.

    This publication is mapped to 29645 other entries.

  14. 14
    Category: Function, Pathology & Biotech.
    Source: MGI:2384909.

    This publication is mapped to 35149 other entries.

  15. 15
    "Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter."
    Baughman J.M., Perocchi F., Girgis H.S., Plovanich M., Belcher-Timme C.A., Sancak Y., Bao X.R., Strittmatter L., Goldberger O., Bogorad R.L., Koteliansky V., Mootha V.K.
    Nature 476:341-345(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location, Interaction.
    Source: MGI:2384909.

    This publication is cited by 2 and mapped to 8 other entries.

  16. 16
    Category: Function, Subcellular Location.
    Source: MGI:2384909.

    This publication is mapped to 2 other entries.

  17. 17
    "MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload."
    Liu J.C., Liu J., Holmstrom K.M., Menazza S., Parks R.J., Fergusson M.M., Yu Z.X., Springer D.A., Halsey C., Liu C., Murphy E., Finkel T.
    Cell Rep 16:1561-1573(2016) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: that MICU1 serves as a molecular gatekeeper preventing calcium overload and suggests that modulating the calcium uniporter could have widespread therapeutic benefits. [GeneRIF:216001].
    Source: MGI:2384909, GeneRIF:216001.

    This publication is mapped to 6 other entries.

  18. 18
    "A MICU1 Splice Variant Confers High Sensitivity to the Mitochondrial Ca<sup>2+</sup> Uptake Machinery of Skeletal Muscle."
    Vecellio Reane D., Vallese F., Checchetto V., Acquasaliente L., Butera G., De Filippis V., Szabo I., Zanotti G., Rizzuto R., Raffaello A.
    Mol Cell 64:760-773(2016) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Interaction.
    Annotation: A MICU1 splice variant confers high sensitivity to the mitochondrial Ca(2+) uptake machinery of skeletal muscle. [GeneRIF:216001].
    Source: MGI:2384909, GeneRIF:216001.

    This publication is mapped to 2 other entries.

  19. 19
    "Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca<sup>2+</sup> Signals Is Controlled by the Stoichiometry of MICU1/2 and MCU."
    Paillard M., Csordas G., Szanda G., Golenar T., Debattisti V., Bartok A., Wang N., Moffat C., Seifert E.L., Spat A., Hajnoczky G.
    Cell Rep 18:2291-2300(2017) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: a possible role for tissue-specific stoichiometry between the Ca(2+)-sensing regulators (MICUs) and pore unit (MCU) of the uniporter was investigated. [GeneRIF:216001].
    Source: MGI:2384909, GeneRIF:216001.

    This publication is mapped to 5 other entries.

  20. 20
    "MICU1 Alleviates Diabetic Cardiomyopathy Through Mitochondrial Ca<sup>2+</sup>-Dependent Antioxidant Response."
    Ji L., Liu F., Jing Z., Huang Q., Zhao Y., Cao H., Li J., Yin C., Xing J., Li F.
    Diabetes 66:1586-1600(2017) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: MICU1 was downregulated in db/db mouse hearts which contributes to myocardial apoptosis in diabetes. Importantly the reconstitution of MICU1 in diabetic hearts significantly inhibited the development of diabetic cardiomyopathy as evidenced by enhanced cardiac function and reduced cardiac hypertrophy and myocardial fibrosis in db/db mice. [GeneRIF:216001].
    Source: MGI:2384909, GeneRIF:216001.

    This publication is mapped to 8 other entries.

  21. 21
    "MICU1 protects against myocardial ischemia/reperfusion injury and its control by the importer receptor Tom70."
    Xue Q., Pei H., Liu Q., Zhao M., Sun J., Gao E., Ma X., Tao L.
    Cell Death Dis 8:e2923-e2923(2017) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location, Pathology & Biotech.
    Annotation: MICU1 exerted protection against myocardial ischemia/reperfusion injury via prevention of mitochondrial Ca2+ overload preservation of mitochondrial integrity and promotion of mitochondrial energy metabolism.
    Source: GeneRIF:216001.
  22. 22
    Category: Function, Expression.
    Annotation: FOXD1-dependent MICU1 expression regulates mitochondrial activity and cell differentiation. [GeneRIF:216001].
    Source: MGI:2384909, GeneRIF:216001.

    This publication is mapped to 11 other entries.

  23. 23
    "MICU1 Interacts with the D-Ring of the MCU Pore to Control Its Ca<sup>2+</sup> Flux and Sensitivity to Ru360."
    Paillard M., Csordas G., Huang K.T., Varnai P., Joseph S.K., Hajnoczky G.
    Mol Cell 72:778-785.e3(2018) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Interaction.
    Annotation: Authors propose that MICU1 has to interact with the D-ring formed by the DIME domains in MCU to control the uniporter. [GeneRIF:216001].
    Source: MGI:2384909, GeneRIF:216001.

    This publication is mapped to 3 other entries.

  24. 24
    "Crystal structure of MICU2 and comparison with MICU1 reveal insights into the uniporter gating mechanism."
    Kamer K.J., Jiang W., Kaushik V.K., Mootha V.K., Grabarek Z.
    Proc Natl Acad Sci U S A 116:3546-3555(2019) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction, Structure.
    Annotation: s. We propose that in the MICU1-MICU2 oligomeric complex the C-terminal helices of both proteins form a central semiautonomous assembly which contributes to the gating mechanism of the uniporter.
    Source: GeneRIF:216001.

    This publication is mapped to 1 other entry.

  25. 25
    "Dysregulation of Mitochondrial Ca<sup>2+</sup> Uptake and Sarcolemma Repair Underlie Muscle Weakness and Wasting in Patients and Mice Lacking MICU1."
    Debattisti V., Horn A., Singh R., Seifert E.L., Hogarth M.W., Mazala D.A., Huang K.T., Horvath R., Jaiswal J.K., Hajnoczky G.
    Cell Rep 29:1274-1286.e6(2019) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: Dysregulation of Mitochondrial Ca(2+) Uptake and Sarcolemma Repair Underlie Muscle Weakness and Wasting in Patients and Mice Lacking MICU1. [GeneRIF:216001].
    Source: MGI:2384909, GeneRIF:216001.

    This publication is mapped to 3 other entries.

1 to 25 of 25  Show
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