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Protein

Trehalase

Gene

Treh

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Alpha,alpha-trehalose + H2O = beta-D-glucose + alpha-D-glucose.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseUniRule annotation, Hydrolase

Protein family/group databases

CAZyiGH37 Glycoside Hydrolase Family 37

Names & Taxonomyi

Protein namesi
Recommended name:
TrehalaseUniRule annotation (EC:3.2.1.28UniRule annotation)
Alternative name(s):
Alpha-trehalose glucohydrolaseUniRule annotation
Gene namesi
Name:TrehImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1926230 Treh

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500431582921 – 541TrehalaseSequence analysisAdd BLAST521

Proteomic databases

PRIDEiQ8VCS8

Structurei

3D structure databases

ProteinModelPortaliQ8VCS8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 37 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0602 Eukaryota
COG1626 LUCA
HOGENOMiHOG000215465
HOVERGENiHBG073526

Family and domain databases

Gene3Di1.50.10.10, 1 hit
InterProiView protein in InterPro
IPR008928 6-hairpin_glycosidase_sf
IPR012341 6hp_glycosidase-like_sf
IPR001661 Glyco_hydro_37
IPR018232 Glyco_hydro_37_CS
PANTHERiPTHR23403 PTHR23403, 1 hit
PfamiView protein in Pfam
PF01204 Trehalase, 1 hit
PRINTSiPR00744 GLHYDRLASE37
SUPFAMiSSF48208 SSF48208, 1 hit
PROSITEiView protein in PROSITE
PS00928 TREHALASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8VCS8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTWELHLLLL LGLGLRSQEA LPPPCERSTA MESSCTKFRW PSSTKMTSSL
60 70 80 90 100
WICHWPHLQM KSCRSSVSWP QSTTTASPRN SFRNLSRVTS SPWGRSCSPG
110 120 130 140 150
PLRTGRTALS SCRRSRMLIC VSGRRSYTRS GKSWERRDSY WVMEGLLLSE
160 170 180 190 200
MASTVKGMLQ NFLDLVKTYG HIPNGGRIYY LQRSQPPLLT LMMDRYVAHT
210 220 230 240 250
KDVAFLQENI GTLASELDFW TVNRTVSVVS GGQSYVLNRY YVPYGGPRPE
260 270 280 290 300
SYRKDAELAN SVPEGDRETL WAELKAGAES GWDFSSRWLV GGPDPDLLSS
310 320 330 340 350
IRTSKMVPAD LNAFLCQAEE LMSNFYSRLG NNTEATKYRN LRAQRLAAME
360 370 380 390 400
AVLWDEQKGA WFDYDLEKGK KNLEFYPSNL TPLWAGCFSD PSVADKALKY
410 420 430 440 450
LEDSKILTYQ YGIPTSLRNT GQQWDFPNAW APLQDLVIRG LAKSASPRTQ
460 470 480 490 500
EVAFQLAQNW IKTNFKVYSQ KSAMFEKYDI SNGGHPGGGG EYEVQEGFGW
510 520 530 540
TNGLALMLLD RYGDQLTSGT QLASLGPHCL VAALLLSLLL Q
Length:541
Mass (Da):60,840
Last modified:March 1, 2002 - v1
Checksum:i05A27E32C3A2875F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC019214 mRNA Translation: AAH19214.1
UniGeneiMm.45380

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC019214 mRNA Translation: AAH19214.1
UniGeneiMm.45380

3D structure databases

ProteinModelPortaliQ8VCS8
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH37 Glycoside Hydrolase Family 37

Proteomic databases

PRIDEiQ8VCS8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1926230 Treh

Phylogenomic databases

eggNOGiKOG0602 Eukaryota
COG1626 LUCA
HOGENOMiHOG000215465
HOVERGENiHBG073526

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

Gene3Di1.50.10.10, 1 hit
InterProiView protein in InterPro
IPR008928 6-hairpin_glycosidase_sf
IPR012341 6hp_glycosidase-like_sf
IPR001661 Glyco_hydro_37
IPR018232 Glyco_hydro_37_CS
PANTHERiPTHR23403 PTHR23403, 1 hit
PfamiView protein in Pfam
PF01204 Trehalase, 1 hit
PRINTSiPR00744 GLHYDRLASE37
SUPFAMiSSF48208 SSF48208, 1 hit
PROSITEiView protein in PROSITE
PS00928 TREHALASE_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ8VCS8_MOUSE
AccessioniPrimary (citable) accession number: Q8VCS8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: May 23, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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