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Entry version 133 (12 Aug 2020)
Sequence version 1 (01 Mar 2002)
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Protein

Pleckstrin homology domain-containing family H member 3

Gene

Plekhh3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Pleckstrin homology domain-containing family H member 3
Short name:
PH domain-containing family H member 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Plekhh3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2384950, Plekhh3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 18Sequence analysisAdd BLAST18
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000031110919 – 796Pleckstrin homology domain-containing family H member 3Add BLAST778

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei30PhosphoserineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi474N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei638Omega-N-methylarginineBy similarity1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Glycoprotein, Methylation, Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8VCE9

PRoteomics IDEntifications database

More...
PRIDEi
Q8VCE9

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q8VCE9, 1 site

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8VCE9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8VCE9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000035172, Expressed in cardiac ventricle and 210 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8VCE9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8VCE9, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
229859, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000046044

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8VCE9, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8VCE9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini95 – 199PHPROSITE-ProRule annotationAdd BLAST105
Domaini237 – 399MyTH4PROSITE-ProRule annotationAdd BLAST163
Domaini404 – 757FERMPROSITE-ProRule annotationAdd BLAST354

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4229, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159764

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001626_4_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8VCE9

Identification of Orthologs from Complete Genome Data

More...
OMAi
PESEMDN

Database of Orthologous Groups

More...
OrthoDBi
478730at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8VCE9

TreeFam database of animal gene trees

More...
TreeFami
TF327852

Family and domain databases

Conserved Domains Database

More...
CDDi
cd14473, FERM_B-lobe, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.80.10, 1 hit
1.25.40.530, 1 hit
2.30.29.30, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019749, Band_41_domain
IPR014352, FERM/acyl-CoA-bd_prot_sf
IPR035963, FERM_2
IPR019748, FERM_central
IPR000299, FERM_domain
IPR000857, MyTH4_dom
IPR038185, MyTH4_dom_sf
IPR011993, PH-like_dom_sf
IPR001849, PH_domain
IPR000159, RA_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00373, FERM_M, 1 hit
PF00784, MyTH4, 1 hit
PF00788, RA, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00295, B41, 1 hit
SM00139, MyTH4, 1 hit
SM00233, PH, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47031, SSF47031, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50057, FERM_3, 1 hit
PS51016, MYTH4, 1 hit
PS50003, PH_DOMAIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8VCE9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MPLPGGLWWL LCCRRGFTLL HRDYGDGELS GDGDEDEDDE TFELRTPSPA
60 70 80 90 100
GGGRGSLDVT LTQPTRNGPI SDRLQGWEET WSLIPDKGLP EEDPDIIVKG
110 120 130 140 150
WLYREPRGGG ARPWLLPRRA WFVLTRDSLD QFSSSGKGAR RLGSLVLTSL
160 170 180 190 200
CSVTGPERRP KETGLWSVTV SGRKHSIRLC SPRQAEAERW GVALREVIAS
210 220 230 240 250
KAPLETPTQL LLRDIQESCG DPEAVALIYR RNPILRHTSS ALYAPLLPLP
260 270 280 290 300
YEVSAPGPGY APLREEAVRL FLALQALEGA RRPGPLMQGV LQTCRDLPAL
310 320 330 340 350
QDELFLQLAK QTSGPAGPPG LPATQDPATL RYWQLLTCMS CTFRPGGAVR
360 370 380 390 400
GHLLGHLERT EQALPDSELA EYARFIRKAL GRTRGRELVP SLAEISALSR
410 420 430 440 450
RQELLCTVHC PGAGACPVSI DSHTTAGEVA RELVGRLGLA RSRNAFALYE
460 470 480 490 500
QRGAQERALA GGTLVADVLT RFENLTSEEA GLEDSPDCGW RLCLRLHGPL
510 520 530 540 550
HPEGLSPEGH ELPFLFEQAH ALLLRGRPPP PEDTLRALAA LRLQSLHRDF
560 570 580 590 600
SPRGPLPLLD RLLPPPIPPR EQPPCPTRRP PPSAALLAGA LWSPGLAKRR
610 620 630 640 650
AERARRGGTG RSTGSTAQVG GGGASTTAAV LGGWKRLRGM GQAEAMAAYL
660 670 680 690 700
ALAAQCPGFG AARYDVLELS TEPGGGAPQK LCLGLGAKAM SLSRPGETEP
710 720 730 740 750
IHSVSYGHVA ACQLIGPHTL ALRVGDSQLL LQSPQVEEIM ELVNAYLANP
760 770 780 790
SPERPCRSGS SSGPPSQDLP DTSPPSQHQV LEEPQGQSGC LKQLQD
Length:796
Mass (Da):85,842
Last modified:March 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i343C40578FBC0F24
GO
Isoform 2 (identifier: Q8VCE9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     471-474: RFEN → S

Show »
Length:793
Mass (Da):85,382
Checksum:iF852147E0DF71399
GO
Isoform 3 (identifier: Q8VCE9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     471-474: RFEN → S
     664-705: YDVLELSTEP...GETEPIHSVS → SLVEVLHRSS...SAMVMWPPAS
     706-796: Missing.

Show »
Length:702
Mass (Da):76,108
Checksum:iB6A0593B2D8ADEEF
GO
Isoform 4 (identifier: Q8VCE9-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     664-705: YDVLELSTEP...GETEPIHSVS → SLVEVLHRSS...SAMVMWPPAS
     706-796: Missing.

Show »
Length:705
Mass (Da):76,568
Checksum:i089B02003C28767D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0QWE8M0QWE8_MOUSE
Pleckstrin homology domain-containi...
Plekhh3
320Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A2A4L0A2A4L0_MOUSE
Pleckstrin homology domain-containi...
Plekhh3
247Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_029399471 – 474RFEN → S in isoform 2 and isoform 3. 2 Publications4
Alternative sequenceiVSP_029400664 – 705YDVLE…IHSVS → SLVEVLHRSSAWVWEQRPCR SPGLVRQNPSTVSAMVMWPP AS in isoform 3 and isoform 4. 2 PublicationsAdd BLAST42
Alternative sequenceiVSP_029401706 – 796Missing in isoform 3 and isoform 4. 2 PublicationsAdd BLAST91

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK154510 mRNA Translation: BAE32639.1
AL590969 Genomic DNA No translation available.
BC020025 mRNA Translation: AAH20025.1
BC024538 mRNA Translation: AAH24538.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS25453.1 [Q8VCE9-1]
CCDS83899.1 [Q8VCE9-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001333698.1, NM_001346769.1 [Q8VCE9-2]
NP_666142.1, NM_146030.2 [Q8VCE9-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000043397; ENSMUSP00000046044; ENSMUSG00000035172 [Q8VCE9-1]
ENSMUST00000129895; ENSMUSP00000137841; ENSMUSG00000035172 [Q8VCE9-4]
ENSMUST00000164474; ENSMUSP00000127088; ENSMUSG00000035172 [Q8VCE9-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
217198

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:217198

UCSC genome browser

More...
UCSCi
uc007lnq.2, mouse [Q8VCE9-1]
uc007lnr.2, mouse [Q8VCE9-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK154510 mRNA Translation: BAE32639.1
AL590969 Genomic DNA No translation available.
BC020025 mRNA Translation: AAH20025.1
BC024538 mRNA Translation: AAH24538.1
CCDSiCCDS25453.1 [Q8VCE9-1]
CCDS83899.1 [Q8VCE9-2]
RefSeqiNP_001333698.1, NM_001346769.1 [Q8VCE9-2]
NP_666142.1, NM_146030.2 [Q8VCE9-1]

3D structure databases

SMRiQ8VCE9
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi229859, 1 interactor
STRINGi10090.ENSMUSP00000046044

PTM databases

GlyGeniQ8VCE9, 1 site
iPTMnetiQ8VCE9
PhosphoSitePlusiQ8VCE9

Proteomic databases

PaxDbiQ8VCE9
PRIDEiQ8VCE9

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
29328, 31 antibodies

Genome annotation databases

EnsembliENSMUST00000043397; ENSMUSP00000046044; ENSMUSG00000035172 [Q8VCE9-1]
ENSMUST00000129895; ENSMUSP00000137841; ENSMUSG00000035172 [Q8VCE9-4]
ENSMUST00000164474; ENSMUSP00000127088; ENSMUSG00000035172 [Q8VCE9-2]
GeneIDi217198
KEGGimmu:217198
UCSCiuc007lnq.2, mouse [Q8VCE9-1]
uc007lnr.2, mouse [Q8VCE9-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
79990
MGIiMGI:2384950, Plekhh3

Phylogenomic databases

eggNOGiKOG4229, Eukaryota
GeneTreeiENSGT00940000159764
HOGENOMiCLU_001626_4_0_1
InParanoidiQ8VCE9
OMAiPESEMDN
OrthoDBi478730at2759
PhylomeDBiQ8VCE9
TreeFamiTF327852

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
217198, 1 hit in 18 CRISPR screens

Protein Ontology

More...
PROi
PR:Q8VCE9
RNActiQ8VCE9, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000035172, Expressed in cardiac ventricle and 210 other tissues
ExpressionAtlasiQ8VCE9, baseline and differential
GenevisibleiQ8VCE9, MM

Family and domain databases

CDDicd14473, FERM_B-lobe, 1 hit
Gene3Di1.20.80.10, 1 hit
1.25.40.530, 1 hit
2.30.29.30, 2 hits
InterProiView protein in InterPro
IPR019749, Band_41_domain
IPR014352, FERM/acyl-CoA-bd_prot_sf
IPR035963, FERM_2
IPR019748, FERM_central
IPR000299, FERM_domain
IPR000857, MyTH4_dom
IPR038185, MyTH4_dom_sf
IPR011993, PH-like_dom_sf
IPR001849, PH_domain
IPR000159, RA_dom
PfamiView protein in Pfam
PF00373, FERM_M, 1 hit
PF00784, MyTH4, 1 hit
PF00788, RA, 1 hit
SMARTiView protein in SMART
SM00295, B41, 1 hit
SM00139, MyTH4, 1 hit
SM00233, PH, 1 hit
SUPFAMiSSF47031, SSF47031, 1 hit
PROSITEiView protein in PROSITE
PS50057, FERM_3, 1 hit
PS51016, MYTH4, 1 hit
PS50003, PH_DOMAIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPKHH3_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8VCE9
Secondary accession number(s): Q3U3Z6, Q8R1H2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: March 1, 2002
Last modified: August 12, 2020
This is version 133 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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