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Protein

DnaJ homolog subfamily C member 28

Gene

Dnajc28

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May have a role in protein folding or as a chaperone.

GO - Biological processi

Keywordsi

Molecular functionChaperone

Names & Taxonomyi

Protein namesi
Recommended name:
DnaJ homolog subfamily C member 28
Gene namesi
Name:Dnajc28
Synonyms:ORF28
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:2181053 Dnajc28

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000711401 – 385DnaJ homolog subfamily C member 28Add BLAST385

Proteomic databases

MaxQBiQ8VCE1
PaxDbiQ8VCE1
PRIDEiQ8VCE1

PTM databases

PhosphoSitePlusiQ8VCE1

Expressioni

Gene expression databases

BgeeiENSMUSG00000039763 Expressed in 202 organ(s), highest expression level in heart
ExpressionAtlasiQ8VCE1 baseline and differential
GenevisibleiQ8VCE1 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000132288

Structurei

3D structure databases

ProteinModelPortaliQ8VCE1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 132JPROSITE-ProRule annotationAdd BLAST85

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili261 – 318Sequence analysisAdd BLAST58

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG0568 Eukaryota
ENOG410ZU5V LUCA
GeneTreeiENSGT00390000008217
HOGENOMiHOG000010237
HOVERGENiHBG051232
InParanoidiQ8VCE1
KOiK19373
PhylomeDBiQ8VCE1
TreeFamiTF323730

Family and domain databases

CDDicd06257 DnaJ, 1 hit
Gene3Di1.10.287.110, 1 hit
InterProiView protein in InterPro
IPR001623 DnaJ_domain
IPR018961 DnaJ_homolog_subfam-C_membr-28
IPR036869 J_dom_sf
PfamiView protein in Pfam
PF00226 DnaJ, 1 hit
PF09350 DUF1992, 1 hit
SMARTiView protein in SMART
SM00271 DnaJ, 1 hit
SUPFAMiSSF46565 SSF46565, 1 hit
PROSITEiView protein in PROSITE
PS50076 DNAJ_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q8VCE1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MINTVCMKTT RILRLHLTNA SLIPPGIKML SDPRSRMIST HESQKLREYY
60 70 80 90 100
RLLNLDEGCS VDDVRESFHK LARQYHPDSG SSDADSATFI KIEEAYRNVL
110 120 130 140 150
SHAIKRMHAG QDKAEDAAED EEEGKFKYNT PQHRHYLSFE GVGFGTPSQR
160 170 180 190 200
EKQYRQFRAD RATEQVMEYQ RQKLQREFFA NSITVKDVRQ SKQQKITQAI
210 220 230 240 250
ERLVEDLIQE SMAKGDFDNL SGKGKPLKKF SGCSYIDPMT HNLNRILIDN
260 270 280 290 300
GYQPEWILMQ KEIKDTIEQL REALLMSRKK LGNPLSPTEQ KQWAQVCEQF
310 320 330 340 350
QEKIRKLNKR INDFNLIVPI LTRQKVHFDA QKEIIRVQEM YGAFVEANEV
360 370 380
TEENQTDVSQ GEESKTPRVK AGFLNWLNLW KSIKI
Length:385
Mass (Da):44,873
Last modified:November 3, 2009 - v2
Checksum:iC7E5DACE342C8943
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9Q1L7E9Q1L7_MOUSE
DnaJ homolog subfamily C member 28
Dnajc28
409Annotation score:
D3Z0T8D3Z0T8_MOUSE
DnaJ homolog subfamily C member 28
Dnajc28
84Annotation score:
D3Z032D3Z032_MOUSE
DnaJ homolog subfamily C member 28
Dnajc28
196Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC005604 mRNA Translation: AAH05604.1
BC020175 mRNA Translation: AAH20175.2
CCDSiCCDS49911.1
RefSeqiNP_619605.2, NM_138664.2
UniGeneiMm.101927

Genome annotation databases

EnsembliENSMUST00000049244; ENSMUSP00000048113; ENSMUSG00000039763
GeneIDi246738
KEGGimmu:246738
UCSCiuc007zxt.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC005604 mRNA Translation: AAH05604.1
BC020175 mRNA Translation: AAH20175.2
CCDSiCCDS49911.1
RefSeqiNP_619605.2, NM_138664.2
UniGeneiMm.101927

3D structure databases

ProteinModelPortaliQ8VCE1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000132288

PTM databases

PhosphoSitePlusiQ8VCE1

Proteomic databases

MaxQBiQ8VCE1
PaxDbiQ8VCE1
PRIDEiQ8VCE1

Protocols and materials databases

DNASUi246738
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000049244; ENSMUSP00000048113; ENSMUSG00000039763
GeneIDi246738
KEGGimmu:246738
UCSCiuc007zxt.1 mouse

Organism-specific databases

CTDi54943
MGIiMGI:2181053 Dnajc28

Phylogenomic databases

eggNOGiKOG0568 Eukaryota
ENOG410ZU5V LUCA
GeneTreeiENSGT00390000008217
HOGENOMiHOG000010237
HOVERGENiHBG051232
InParanoidiQ8VCE1
KOiK19373
PhylomeDBiQ8VCE1
TreeFamiTF323730

Miscellaneous databases

PROiPR:Q8VCE1
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000039763 Expressed in 202 organ(s), highest expression level in heart
ExpressionAtlasiQ8VCE1 baseline and differential
GenevisibleiQ8VCE1 MM

Family and domain databases

CDDicd06257 DnaJ, 1 hit
Gene3Di1.10.287.110, 1 hit
InterProiView protein in InterPro
IPR001623 DnaJ_domain
IPR018961 DnaJ_homolog_subfam-C_membr-28
IPR036869 J_dom_sf
PfamiView protein in Pfam
PF00226 DnaJ, 1 hit
PF09350 DUF1992, 1 hit
SMARTiView protein in SMART
SM00271 DnaJ, 1 hit
SUPFAMiSSF46565 SSF46565, 1 hit
PROSITEiView protein in PROSITE
PS50076 DNAJ_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiDJC28_MOUSE
AccessioniPrimary (citable) accession number: Q8VCE1
Secondary accession number(s): Q99JX0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2002
Last sequence update: November 3, 2009
Last modified: November 7, 2018
This is version 109 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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