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Entry version 116 (29 Sep 2021)
Sequence version 1 (01 Mar 2002)
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Protein

Transmembrane protein 161A

Gene

Tmem161a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis (By similarity).

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transmembrane protein 161A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2384577, Tmem161a

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSMUSG00000002342

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini29 – 98ExtracellularSequence analysisAdd BLAST70
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei99 – 119HelicalSequence analysisAdd BLAST21
Topological domaini120 – 134CytoplasmicSequence analysisAdd BLAST15
Transmembranei135 – 155HelicalSequence analysisAdd BLAST21
Topological domaini156 – 166ExtracellularSequence analysisAdd BLAST11
Transmembranei167 – 187HelicalSequence analysisAdd BLAST21
Topological domaini188 – 224CytoplasmicSequence analysisAdd BLAST37
Transmembranei225 – 245HelicalSequence analysisAdd BLAST21
Topological domaini246 – 263ExtracellularSequence analysisAdd BLAST18
Transmembranei264 – 284HelicalSequence analysisAdd BLAST21
Topological domaini285 – 304CytoplasmicSequence analysisAdd BLAST20
Transmembranei305 – 325HelicalSequence analysisAdd BLAST21
Topological domaini326 – 370ExtracellularSequence analysisAdd BLAST45
Transmembranei371 – 391HelicalSequence analysisAdd BLAST21
Topological domaini392 – 450CytoplasmicSequence analysisAdd BLAST59
Transmembranei451 – 473HelicalSequence analysisAdd BLAST23
Topological domaini474 – 480ExtracellularSequence analysis7

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 28Sequence analysisAdd BLAST28
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000028808529 – 480Transmembrane protein 161AAdd BLAST452

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi34N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8VCA6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8VCA6

PRoteomics IDEntifications database

More...
PRIDEi
Q8VCA6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
263217 [Q8VCA6-1]
263218 [Q8VCA6-2]
263219 [Q8VCA6-3]

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q8VCA6, 1 site

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8VCA6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000002342, Expressed in fibroblast and 295 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8VCA6, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8VCA6, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000002413

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8VCA6, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8VCA6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TMEM161 family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3978, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000000672

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_027277_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8VCA6

Identification of Orthologs from Complete Genome Data

More...
OMAi
MALMGIQ

Database of Orthologous Groups

More...
OrthoDBi
734854at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8VCA6

TreeFam database of animal gene trees

More...
TreeFami
TF314570

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019395, Transmembrane_161A/B

The PANTHER Classification System

More...
PANTHERi
PTHR13624, PTHR13624, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10268, Tmemb_161AB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8VCA6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAVLGVQLVV TLFTATLMHR LAPHCSFARW LLCNGSLFRY IHPSEEELRA
60 70 80 90 100
LSGKLRPRVR KERWANGLHD EKPLSVPRDA HFQLQTCPLT AVDALVLRFF
110 120 130 140 150
LEYQWFVDFA VYSVGVYLFT EAYYFVLGPV QETNIAVFWC LLTLAFSLKV
160 170 180 190 200
FLMVTRLYFS TKEGGERSVC LSFAFLFLLL AMLVQVVREE TLELGLEPGL
210 220 230 240 250
ASMTQHLEPI LKKQDWDWTL PVIKLAIRLG LAVLGSLLGA FLIFPGLRLA
260 270 280 290 300
QTHQDALTLS ADRPLLQLLL HTSFLSPLCT LWLWTKPVAR DFLYQAPTRN
310 320 330 340 350
MTFSVPSEGA FDSLRLWVLV ALCLLRLAVT RPHLQAYLCL AKARVEQLRK
360 370 380 390 400
EAGRIEAREI QQRVVRVYCY VTVVSLQYLT PLILTLHCTL LLKTLGGYSW
410 420 430 440 450
ALSSTPPPLA PSQPSEALIP VDPAGDEAQQ TAAQVAGILG GLLTPLFLRG
460 470 480
MLAYIIWWTA ACQLLSSLFG LYFHQHLAAS
Length:480
Mass (Da):54,015
Last modified:March 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i511D268E06DA2EE8
GO
Isoform 2 (identifier: Q8VCA6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-152: Missing.

Show »
Length:328
Mass (Da):36,460
Checksum:i1CF3C5FEE257F4E9
GO
Isoform 3 (identifier: Q8VCA6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-196: Missing.
     197-198: EP → MA

Show »
Length:284
Mass (Da):31,443
Checksum:iFAD6BE1D7B7A97D6
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0QWV0M0QWV0_MOUSE
Transmembrane protein 161A
Tmem161a
323Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6UNW2F6UNW2_MOUSE
Transmembrane protein 161A
Tmem161a
454Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R1Z2S4R1Z2_MOUSE
Transmembrane protein 161A
Tmem161a
192Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R2H0S4R2H0_MOUSE
Transmembrane protein 161A
Tmem161a
126Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0QWE7M0QWE7_MOUSE
Transmembrane protein 161A
Tmem161a
57Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC40428 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti342K → E in BAC27995 (PubMed:16141072).Curated1
Sequence conflicti423P → L in BAC40428 (PubMed:16141072).Curated1
Sequence conflicti439L → V in BAC40428 (PubMed:16141072).Curated1
Sequence conflicti464L → M in BAC40428 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0256431 – 196Missing in isoform 3. 1 PublicationAdd BLAST196
Alternative sequenceiVSP_0256441 – 152Missing in isoform 2. 1 PublicationAdd BLAST152
Alternative sequenceiVSP_025645197 – 198EP → MA in isoform 3. 1 Publication2

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK032711 mRNA Translation: BAC27995.1
AK049979 mRNA Translation: BAC34016.1
AK082916 mRNA Translation: BAC38686.1
AK088569 mRNA Translation: BAC40428.1 Different initiation.
AK147962 mRNA Translation: BAE28253.1
BC021367 mRNA Translation: AAH21367.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS40369.1 [Q8VCA6-1]
CCDS80890.1 [Q8VCA6-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001280726.1, NM_001293797.1 [Q8VCA6-2]
NP_663572.1, NM_145597.4 [Q8VCA6-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000002413; ENSMUSP00000002413; ENSMUSG00000002342 [Q8VCA6-1]
ENSMUST00000182980; ENSMUSP00000138499; ENSMUSG00000002342 [Q8VCA6-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
234371

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:234371

UCSC genome browser

More...
UCSCi
uc009lzc.2, mouse [Q8VCA6-1]
uc012geu.2, mouse [Q8VCA6-3]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK032711 mRNA Translation: BAC27995.1
AK049979 mRNA Translation: BAC34016.1
AK082916 mRNA Translation: BAC38686.1
AK088569 mRNA Translation: BAC40428.1 Different initiation.
AK147962 mRNA Translation: BAE28253.1
BC021367 mRNA Translation: AAH21367.1
CCDSiCCDS40369.1 [Q8VCA6-1]
CCDS80890.1 [Q8VCA6-2]
RefSeqiNP_001280726.1, NM_001293797.1 [Q8VCA6-2]
NP_663572.1, NM_145597.4 [Q8VCA6-1]

3D structure databases

SMRiQ8VCA6
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000002413

PTM databases

GlyGeniQ8VCA6, 1 site
PhosphoSitePlusiQ8VCA6

Proteomic databases

EPDiQ8VCA6
PaxDbiQ8VCA6
PRIDEiQ8VCA6
ProteomicsDBi263217 [Q8VCA6-1]
263218 [Q8VCA6-2]
263219 [Q8VCA6-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
43982, 152 antibodies

Genome annotation databases

EnsembliENSMUST00000002413; ENSMUSP00000002413; ENSMUSG00000002342 [Q8VCA6-1]
ENSMUST00000182980; ENSMUSP00000138499; ENSMUSG00000002342 [Q8VCA6-2]
GeneIDi234371
KEGGimmu:234371
UCSCiuc009lzc.2, mouse [Q8VCA6-1]
uc012geu.2, mouse [Q8VCA6-3]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
54929
MGIiMGI:2384577, Tmem161a
VEuPathDBiHostDB:ENSMUSG00000002342

Phylogenomic databases

eggNOGiKOG3978, Eukaryota
GeneTreeiENSGT00390000000672
HOGENOMiCLU_027277_0_0_1
InParanoidiQ8VCA6
OMAiMALMGIQ
OrthoDBi734854at2759
PhylomeDBiQ8VCA6
TreeFamiTF314570

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
234371, 2 hits in 97 CRISPR screens

Protein Ontology

More...
PROi
PR:Q8VCA6
RNActiQ8VCA6, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000002342, Expressed in fibroblast and 295 other tissues
ExpressionAtlasiQ8VCA6, baseline and differential
GenevisibleiQ8VCA6, MM

Family and domain databases

InterProiView protein in InterPro
IPR019395, Transmembrane_161A/B
PANTHERiPTHR13624, PTHR13624, 1 hit
PfamiView protein in Pfam
PF10268, Tmemb_161AB, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiT161A_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8VCA6
Secondary accession number(s): Q8BNL7, Q8BSL1, Q8C2I8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: March 1, 2002
Last modified: September 29, 2021
This is version 116 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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