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Protein

Putative RNA polymerase II subunit B1 CTD phosphatase Rpap2

Gene

Rpap2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi100ZincPROSITE-ProRule annotation1
Metal bindingi105ZincPROSITE-ProRule annotation1
Metal bindingi136ZincPROSITE-ProRule annotation1
Metal bindingi140ZincPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri77 – 160RTR1-typePROSITE-ProRule annotationAdd BLAST84

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Protein phosphatase
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-6807505 RNA polymerase II transcribes snRNA genes

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative RNA polymerase II subunit B1 CTD phosphatase Rpap2 (EC:3.1.3.16)
Alternative name(s):
RNA polymerase II-associated protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Rpap2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2141142 Rpap2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002506492 – 614Putative RNA polymerase II subunit B1 CTD phosphatase Rpap2Add BLAST613

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineBy similarity1
Modified residuei9PhosphoserineBy similarity1
Modified residuei217PhosphoserineBy similarity1
Modified residuei481PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8VC34

PeptideAtlas

More...
PeptideAtlasi
Q8VC34

PRoteomics IDEntifications database

More...
PRIDEi
Q8VC34

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8VC34

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8VC34

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000033773 Expressed in 265 organ(s), highest expression level in primary oocyte

CleanEx database of gene expression profiles

More...
CleanExi
MM_RPAP2

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8VC34 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8VC34 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Associates with the RNA polymerase II complex. Interacts with transcribing RNA polymerase II phosphorylated on 'Ser-7' on CTD (By similarity).By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000070209

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q8VC34

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8VC34

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili41 – 68Sequence analysisAdd BLAST28

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RPAP2 family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri77 – 160RTR1-typePROSITE-ProRule annotationAdd BLAST84

Keywords - Domaini

Coiled coil, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4780 Eukaryota
ENOG410ZZZC LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000017965

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000253960

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG080953

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8VC34

KEGG Orthology (KO)

More...
KOi
K20827

Identification of Orthologs from Complete Genome Data

More...
OMAi
CYRASKY

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0TLM

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8VC34

TreeFam database of animal gene trees

More...
TreeFami
TF331431

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.820, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039693 Rtr1/RPAP2
IPR007308 Rtr1/RPAP2_dom
IPR038534 Rtr1/RPAP2_sf

The PANTHER Classification System

More...
PANTHERi
PTHR14732 PTHR14732, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04181 RPAP2_Rtr1, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51479 ZF_RTR1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 5 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 5 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8VC34-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MADSAVPCSL GPSTRASSTH RDATGTKQTR ALKRGDASKR QAELEAAIQR
60 70 80 90 100
KVEFERKAVR IVEQLLEENI TEEFLKECGM FITPAHYSDV VDERSIIKLC
110 120 130 140 150
GYPLCQKKLG VIPKQKYRIS TKTNKVYDIT ERKSFCSNFC YRASKFFETQ
160 170 180 190 200
IPKTPVWVRE EERPPDFQLL KKGQSGSSGE VVQFFRDAVT AADVDGSGAL
210 220 230 240 250
EAQCDPASSS SWSERASDEE EQGFVSSLLP GNRPKAVDTR PQPHTKSSIM
260 270 280 290 300
RKKAAQNVDS KEGEQTVSEV TEQLDNCRLD SQEKVATCKR PLKKESTQIS
310 320 330 340 350
SPGPLCDRFN TSAISEHKHG VSQVTLVGIS KKSAEHFRSK FAKSNPGSGS
360 370 380 390 400
ASGLVHVRPE VAKANLLRVL SDTLTEWKTE ETLKFLYGQN HDSVCLKPSS
410 420 430 440 450
ASEPDEELDE DDISCDPGSC GPALSQAQNT LDATLPFRGS DTAIKPLPSY
460 470 480 490 500
ESLKKETEML NLRVREFYRG RCVLNEDTTK SQDSKESVLQ RDPSFPLIDS
510 520 530 540 550
SSQNQIRRRI VLEKLSKVLP GLLGPLQITM GDIYTELKNL IQTFRLSNRN
560 570 580 590 600
IIHKPVEWTL IAVVLLLLLT PILGIQKHSP KNVVFTQFIA TLLTELHLKF
610
EDLEKLTMIF RTSC
Length:614
Mass (Da):68,530
Last modified:October 3, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3029373A246478D7
GO
Isoform 2 (identifier: Q8VC34-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     569-570: LT → IL
     571-614: Missing.

Note: No experimental confirmation available.
Show »
Length:570
Mass (Da):63,458
Checksum:iFC6E023D8CCD2587
GO
Isoform 3 (identifier: Q8VC34-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     569-614: Missing.

Note: No experimental confirmation available.
Show »
Length:568
Mass (Da):63,232
Checksum:i423D8CCD2587F3F5
GO
Isoform 4 (identifier: Q8VC34-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-79: Missing.
     569-614: Missing.

Note: No experimental confirmation available.
Show »
Length:489
Mass (Da):54,504
Checksum:iF61E7558CBA75A2F
GO
Isoform 5 (identifier: Q8VC34-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-77: Missing.
     78-78: C → M

Note: No experimental confirmation available.
Show »
Length:537
Mass (Da):59,990
Checksum:i69F5ECA9B2C0AEA4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2JDU8A0A0G2JDU8_MOUSE
Putative RNA polymerase II subunit ...
Rpap2
82Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3Z2V7D3Z2V7_MOUSE
Putative RNA polymerase II subunit ...
Rpap2
53Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti201E → D in AAH21895 (PubMed:15489334).Curated1
Sequence conflicti318K → T in AAH21895 (PubMed:15489334).Curated1
Sequence conflicti444I → V in BAE26681 (PubMed:16141072).Curated1
Sequence conflicti524G → V in BAE38864 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0206821 – 79Missing in isoform 4. 1 PublicationAdd BLAST79
Alternative sequenceiVSP_0206831 – 77Missing in isoform 5. 1 PublicationAdd BLAST77
Alternative sequenceiVSP_02068478C → M in isoform 5. 1 Publication1
Alternative sequenceiVSP_020685569 – 614Missing in isoform 3 and isoform 4. 1 PublicationAdd BLAST46
Alternative sequenceiVSP_020686569 – 570LT → IL in isoform 2. 1 Publication2
Alternative sequenceiVSP_020687571 – 614Missing in isoform 2. 1 PublicationAdd BLAST44

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK034418 mRNA Translation: BAC28703.1
AK049889 mRNA Translation: BAC33973.1
AK145830 mRNA Translation: BAE26681.1
AK161901 mRNA Translation: BAE36627.1
AK166574 mRNA Translation: BAE38864.1
BC021895 mRNA Translation: AAH21895.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS19506.1 [Q8VC34-1]
CCDS51588.1 [Q8VC34-3]
CCDS51589.1 [Q8VC34-4]
CCDS71630.1 [Q8VC34-2]
CCDS71631.1 [Q8VC34-5]

NCBI Reference Sequences

More...
RefSeqi
NP_001156933.1, NM_001163461.2 [Q8VC34-3]
NP_001156934.1, NM_001163462.2 [Q8VC34-4]
NP_001276498.1, NM_001289569.1 [Q8VC34-5]
NP_001276499.1, NM_001289570.1 [Q8VC34-2]
NP_659160.2, NM_144911.3 [Q8VC34-1]
XP_006534963.1, XM_006534900.3 [Q8VC34-5]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.482420

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000065422; ENSMUSP00000070209; ENSMUSG00000033773 [Q8VC34-1]
ENSMUST00000112650; ENSMUSP00000108269; ENSMUSG00000033773 [Q8VC34-4]
ENSMUST00000112651; ENSMUSP00000108270; ENSMUSG00000033773 [Q8VC34-5]
ENSMUST00000112654; ENSMUSP00000108273; ENSMUSG00000033773 [Q8VC34-3]
ENSMUST00000112655; ENSMUSP00000108274; ENSMUSG00000033773 [Q8VC34-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
231571

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:231571

UCSC genome browser

More...
UCSCi
uc008ymn.3 mouse [Q8VC34-1]
uc008ymq.3 mouse [Q8VC34-5]
uc033iky.1 mouse [Q8VC34-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK034418 mRNA Translation: BAC28703.1
AK049889 mRNA Translation: BAC33973.1
AK145830 mRNA Translation: BAE26681.1
AK161901 mRNA Translation: BAE36627.1
AK166574 mRNA Translation: BAE38864.1
BC021895 mRNA Translation: AAH21895.1
CCDSiCCDS19506.1 [Q8VC34-1]
CCDS51588.1 [Q8VC34-3]
CCDS51589.1 [Q8VC34-4]
CCDS71630.1 [Q8VC34-2]
CCDS71631.1 [Q8VC34-5]
RefSeqiNP_001156933.1, NM_001163461.2 [Q8VC34-3]
NP_001156934.1, NM_001163462.2 [Q8VC34-4]
NP_001276498.1, NM_001289569.1 [Q8VC34-5]
NP_001276499.1, NM_001289570.1 [Q8VC34-2]
NP_659160.2, NM_144911.3 [Q8VC34-1]
XP_006534963.1, XM_006534900.3 [Q8VC34-5]
UniGeneiMm.482420

3D structure databases

ProteinModelPortaliQ8VC34
SMRiQ8VC34
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000070209

PTM databases

iPTMnetiQ8VC34
PhosphoSitePlusiQ8VC34

Proteomic databases

PaxDbiQ8VC34
PeptideAtlasiQ8VC34
PRIDEiQ8VC34

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000065422; ENSMUSP00000070209; ENSMUSG00000033773 [Q8VC34-1]
ENSMUST00000112650; ENSMUSP00000108269; ENSMUSG00000033773 [Q8VC34-4]
ENSMUST00000112651; ENSMUSP00000108270; ENSMUSG00000033773 [Q8VC34-5]
ENSMUST00000112654; ENSMUSP00000108273; ENSMUSG00000033773 [Q8VC34-3]
ENSMUST00000112655; ENSMUSP00000108274; ENSMUSG00000033773 [Q8VC34-2]
GeneIDi231571
KEGGimmu:231571
UCSCiuc008ymn.3 mouse [Q8VC34-1]
uc008ymq.3 mouse [Q8VC34-5]
uc033iky.1 mouse [Q8VC34-2]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
79871
MGIiMGI:2141142 Rpap2

Phylogenomic databases

eggNOGiKOG4780 Eukaryota
ENOG410ZZZC LUCA
GeneTreeiENSGT00390000017965
HOGENOMiHOG000253960
HOVERGENiHBG080953
InParanoidiQ8VC34
KOiK20827
OMAiCYRASKY
OrthoDBiEOG091G0TLM
PhylomeDBiQ8VC34
TreeFamiTF331431

Enzyme and pathway databases

ReactomeiR-MMU-6807505 RNA polymerase II transcribes snRNA genes

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Rpap2 mouse

Protein Ontology

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PROi
PR:Q8VC34

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000033773 Expressed in 265 organ(s), highest expression level in primary oocyte
CleanExiMM_RPAP2
ExpressionAtlasiQ8VC34 baseline and differential
GenevisibleiQ8VC34 MM

Family and domain databases

Gene3Di1.25.40.820, 1 hit
InterProiView protein in InterPro
IPR039693 Rtr1/RPAP2
IPR007308 Rtr1/RPAP2_dom
IPR038534 Rtr1/RPAP2_sf
PANTHERiPTHR14732 PTHR14732, 1 hit
PfamiView protein in Pfam
PF04181 RPAP2_Rtr1, 1 hit
PROSITEiView protein in PROSITE
PS51479 ZF_RTR1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRPAP2_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8VC34
Secondary accession number(s): Q3TLC8
, Q3TSP8, Q3UKX0, Q8C7M5, Q8CBW8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: October 3, 2006
Last modified: December 5, 2018
This is version 114 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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