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UniProtKB - Q8TFG1 (GHT7_SCHPO)
Protein
Probable high-affinity hexose transporter ght7
Gene
ght7
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
GO - Molecular functioni
- carbohydrate:proton symporter activity Source: GO_Central
- hexose transmembrane transporter activity Source: PomBase
GO - Biological processi
- carbohydrate transport Source: GO_Central
- hexose transmembrane transport Source: PomBase
Keywordsi
Biological process | Sugar transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Probable high-affinity hexose transporter ght7Short name: Hexose transporter 7 |
Gene namesi | Name:ght7 ORF Names:SPBC1348.14c, SPBPB8B6.01c |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPBC1348.14c, ght7 |
VEuPathDBi | FungiDB:SPBC1348.14c |
Subcellular locationi
Other locations
- Membrane Curated; Multi-pass membrane protein Curated
Endoplasmic reticulum
- endoplasmic reticulum Source: PomBase
Plasma Membrane
- plasma membrane Source: GO_Central
Other locations
- cytoplasm Source: PomBase
- integral component of membrane Source: UniProtKB-KW
- membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 27 | CytoplasmicSequence analysisAdd BLAST | 27 | |
Transmembranei | 28 – 48 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 49 – 54 | ExtracellularSequence analysis | 6 | |
Transmembranei | 55 – 75 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 76 – 77 | CytoplasmicSequence analysis | 2 | |
Transmembranei | 78 – 98 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 99 – 112 | ExtracellularSequence analysisAdd BLAST | 14 | |
Transmembranei | 113 – 133 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 134 – 149 | CytoplasmicSequence analysisAdd BLAST | 16 | |
Transmembranei | 150 – 170 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 171 – 236 | ExtracellularSequence analysisAdd BLAST | 66 | |
Transmembranei | 237 – 257 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 258 – 271 | CytoplasmicSequence analysisAdd BLAST | 14 | |
Transmembranei | 272 – 292 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 293 – 298 | ExtracellularSequence analysis | 6 | |
Transmembranei | 299 – 319 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 320 – 333 | CytoplasmicSequence analysisAdd BLAST | 14 | |
Transmembranei | 334 – 354 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 355 – 374 | ExtracellularSequence analysisAdd BLAST | 20 | |
Transmembranei | 375 – 395 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 396 – 402 | CytoplasmicSequence analysis | 7 | |
Transmembranei | 403 – 423 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 424 – 518 | ExtracellularSequence analysisAdd BLAST | 95 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000050415 | 1 – 518 | Probable high-affinity hexose transporter ght7Add BLAST | 518 |
Proteomic databases
PaxDbi | Q8TFG1 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 278230, 1 interactor |
STRINGi | 4896.SPBC1348.14c.1 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 477 – 518 | DisorderedSequence analysisAdd BLAST | 42 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 477 – 508 | Polar residuesSequence analysisAdd BLAST | 32 |
Sequence similaritiesi
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0254, Eukaryota |
HOGENOMi | CLU_001265_30_1_1 |
InParanoidi | Q8TFG1 |
OMAi | VFQRLIM |
PhylomeDBi | Q8TFG1 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit |
i Sequence
Sequence statusi: Complete.
Q8TFG1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRDFQSRFAD RYNQITNSYS YSSSRQGLIT GMVNVGSFFG CLLSSPVADK
60 70 80 90 100
IGKRLSIIVW TTVYLIGIII QVTTVPSWVQ ILVAKIWTGL SIGALSVITP
110 120 130 140 150
GYQSEVAPAI MRGAIVTTYQ LFITLGIFIA ACINMGTHKY SHGTTAQWRI
160 170 180 190 200
SIGINLLWGI ITLVGIIFLP ESPRYLIAIG KDDEALKIMC YNNDLPLEHE
210 220 230 240 250
IIQTEYHTIK SDCDAELAGG PARWPEIFNA NIRYRTFLGM AVMMFQQLTG
260 270 280 290 300
ANYYFYYGTQ VFRGTGMDSP YLAALIPDAV NCGCTFGAIF VLEFFGRRSP
310 320 330 340 350
LIVGGIWQYI CFFIYAAVGD RALYHKNGTS NHRAGAVMIV FSCLFIFSFS
360 370 380 390 400
QTWAPAAYVI VGESYPVRYR SKCAAVATSA NWFWNFLISF FTPFITNSIG
410 420 430 440 450
FKYGYIFASC NLTGAAIIFL FVHETKGRTL EEINTMYASN LKPWMPHPEG
460 470 480 490 500
YREFGREQNN ATLKSHIGLN GETTELIENT DNQGDSGSFQ TSTPDDSRPE
510
QNQASATYIR PDKREPRL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329671 Genomic DNA Translation: CAD27907.1 |
RefSeqi | NP_001018762.2, NM_001020937.3 |
Genome annotation databases
EnsemblFungii | SPBC1348.14c.1; SPBC1348.14c.1:pep; SPBC1348.14c |
GeneIDi | 2541736 |
KEGGi | spo:SPBC1348.14c |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329671 Genomic DNA Translation: CAD27907.1 |
RefSeqi | NP_001018762.2, NM_001020937.3 |
3D structure databases
SMRi | Q8TFG1 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 278230, 1 interactor |
STRINGi | 4896.SPBC1348.14c.1 |
Proteomic databases
PaxDbi | Q8TFG1 |
Genome annotation databases
EnsemblFungii | SPBC1348.14c.1; SPBC1348.14c.1:pep; SPBC1348.14c |
GeneIDi | 2541736 |
KEGGi | spo:SPBC1348.14c |
Organism-specific databases
PomBasei | SPBC1348.14c, ght7 |
VEuPathDBi | FungiDB:SPBC1348.14c |
Phylogenomic databases
eggNOGi | KOG0254, Eukaryota |
HOGENOMi | CLU_001265_30_1_1 |
InParanoidi | Q8TFG1 |
OMAi | VFQRLIM |
PhylomeDBi | Q8TFG1 |
Miscellaneous databases
PROi | PR:Q8TFG1 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | GHT7_SCHPO | |
Accessioni | Q8TFG1Primary (citable) accession number: Q8TFG1 Secondary accession number(s): Q9P3V2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 13, 2004 |
Last sequence update: | June 1, 2002 | |
Last modified: | February 23, 2022 | |
This is version 122 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names - SIMILARITY comments
Index of protein domains and families