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UniProtKB - Q8TEZ7 (PAQR8_HUMAN)

Entry version 124 (26 Feb 2020)
Sequence version 1 (01 Jun 2002)
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Protein

Membrane progestin receptor beta

Gene

PAQR8

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432). Seems to act through a G(i) mediated pathway (PubMed:23763432). May be involved in oocyte maturation (By similarity). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23161870).1 PublicationBy similarity1 Publication

Miscellaneous

Non-classical progesterone receptors involved in extranuclear signaling are classified in 2 groups: the class II progestin and adipoQ receptor (PAQR) family (also called mPRs) (PAQR5, PAQR6, PAQR7, PAQR8 and PAQR9) and the b5-like heme/steroid-binding protein family (also called MAPRs) (PGRMC1, PGRMC2, NENF and CYB5D2).1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein, Receptor
Biological processDifferentiation, Oogenesis
LigandLipid-binding, Steroid-binding

Protein family/group databases

Transport Classification Database

More...TCDBi		1.C.113.1.12 the hly iii (hly iii) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Membrane progestin receptor beta1 Publication
Short name:
mPR beta1 Publication
Alternative name(s):
Lysosomal membrane protein in brain 11 Publication
Membrane progesterone P4 receptor beta1 Publication
Membrane progesterone receptor beta1 Publication
Progesterone and adipoQ receptor family member 8
Progestin and adipoQ receptor family member 81 Publication
Progestin and adipoQ receptor family member VIII
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PAQR8Imported
Synonyms:C6orf33Imported, LMPB1, MPRB
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:15708 PAQR8

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		607780 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q8TEZ7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 75CytoplasmicSequence analysisAdd BLAST75
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei76 – 96Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini97 – 111ExtracellularSequence analysisAdd BLAST15
Transmembranei112 – 132Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini133 – 174CytoplasmicSequence analysisAdd BLAST42
Transmembranei175 – 195Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini196 – 213ExtracellularSequence analysisAdd BLAST18
Transmembranei214 – 234Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini235 – 243CytoplasmicSequence analysis9
Transmembranei244 – 264Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini265 – 283ExtracellularSequence analysisAdd BLAST19
Transmembranei284 – 304Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini305 – 319CytoplasmicSequence analysisAdd BLAST15
Transmembranei320 – 340Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini341 – 354ExtracellularSequence analysisAdd BLAST14

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		85315

Open Targets

More...OpenTargetsi		ENSG00000170915

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA25934

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q8TEZ7 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		PAQR8

Domain mapping of disease mutations (DMDM)

More...DMDMi		51316493

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002188401 – 354Membrane progestin receptor betaAdd BLAST354

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q8TEZ7

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8TEZ7

PeptideAtlas

More...PeptideAtlasi		Q8TEZ7

PRoteomics IDEntifications database

More...PRIDEi		Q8TEZ7

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		74529

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8TEZ7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8TEZ7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in the hypothalamus (PubMed:23161870). Also expressed in spinal cord, kidney and testis.4 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000170915 Expressed in globus pallidus and 185 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8TEZ7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8TEZ7 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA064625

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...IntActi		Q8TEZ7, 3 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000406197

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8TEZ7 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8TEZ7

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ADIPOR family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0748 Eukaryota
COG1272 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000159860

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_052356_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8TEZ7

Identification of Orthologs from Complete Genome Data

More...OMAi		REPYIHA

Database of Orthologous Groups

More...OrthoDBi		1524940at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8TEZ7

TreeFam database of animal gene trees

More...TreeFami		TF319738

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR004254 AdipoR/HlyIII-related

The PANTHER Classification System

More...PANTHERi		PTHR20855 PTHR20855, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF03006 HlyIII, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q8TEZ7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTTAILERLS TLSVSGQQLR RLPKILEDGL PKMPCTVPET DVPQLFREPY 
        60         70         80         90        100
IRTGYRPTGH EWRYYFFSLF QKHNEVVNVW THLLAALAVL LRFWAFAEAE 
       110        120        130        140        150
ALPWASTHSL PLLLFILSSI TYLTCSLLAH LLQSKSELSH YTFYFVDYVG 
       160        170        180        190        200
VSVYQYGSAL AHFFYSSDQA WYDRFWLFFL PAAAFCGWLS CAGCCYAKYR 
       210        220        230        240        250
YRRPYPVMRK ICQVVPAGLA FILDISPVAH RVALCHLAGC QEQAAWYHTL 
       260        270        280        290        300
QILFFLVSAY FFSCPVPEKY FPGSCDIVGH GHQIFHAFLS ICTLSQLEAI 
       310        320        330        340        350
LLDYQGRQEI FLQRHGPLSV HMACLSFFFL AACSAATAAL LRHKVKARLT 

KKDS
Length:354
Mass (Da):40,464
Last modified:June 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB0ECCD9C54C0CA24
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6RCM7D6RCM7_HUMAN
Membrane progestin receptor beta
PAQR8
112Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAR08374 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF347029 mRNA Translation: AAL79777.2
AY424286 mRNA Translation: AAR08374.1 Different initiation.
AK315088 mRNA Translation: BAG37553.1
AL136125 Genomic DNA No translation available.
BC030664 mRNA Translation: AAH30664.2
AF313619 mRNA Translation: AAO47232.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS4941.1

NCBI Reference Sequences

More...RefSeqi		NP_588608.1, NM_133367.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000360726; ENSP00000353953; ENSG00000170915
ENST00000442253; ENSP00000406197; ENSG00000170915

Database of genes from NCBI RefSeq genomes

More...GeneIDi		85315

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:85315

UCSC genome browser

More...UCSCi		uc003pao.4 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF347029 mRNA Translation: AAL79777.2
AY424286 mRNA Translation: AAR08374.1 Different initiation.
AK315088 mRNA Translation: BAG37553.1
AL136125 Genomic DNA No translation available.
BC030664 mRNA Translation: AAH30664.2
AF313619 mRNA Translation: AAO47232.1
CCDSiCCDS4941.1
RefSeqiNP_588608.1, NM_133367.4

3D structure databases

SMRiQ8TEZ7
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ8TEZ7, 3 interactors
STRINGi9606.ENSP00000406197

Protein family/group databases

TCDBi1.C.113.1.12 the hly iii (hly iii) family

PTM databases

iPTMnetiQ8TEZ7
PhosphoSitePlusiQ8TEZ7

Polymorphism and mutation databases

BioMutaiPAQR8
DMDMi51316493

Proteomic databases

MassIVEiQ8TEZ7
PaxDbiQ8TEZ7
PeptideAtlasiQ8TEZ7
PRIDEiQ8TEZ7
ProteomicsDBi74529

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		85315

Genome annotation databases

EnsembliENST00000360726; ENSP00000353953; ENSG00000170915
ENST00000442253; ENSP00000406197; ENSG00000170915
GeneIDi85315
KEGGihsa:85315
UCSCiuc003pao.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		85315
DisGeNETi85315

GeneCards: human genes, protein and diseases

More...GeneCardsi		PAQR8
HGNCiHGNC:15708 PAQR8
HPAiHPA064625
MIMi607780 gene
neXtProtiNX_Q8TEZ7
OpenTargetsiENSG00000170915
PharmGKBiPA25934

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG0748 Eukaryota
COG1272 LUCA
GeneTreeiENSGT00940000159860
HOGENOMiCLU_052356_0_0_1
InParanoidiQ8TEZ7
OMAiREPYIHA
OrthoDBi1524940at2759
PhylomeDBiQ8TEZ7
TreeFamiTF319738

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		PAQR8 human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		PAQR8

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		85315
PharosiQ8TEZ7 Tbio

Protein Ontology

More...PROi		PR:Q8TEZ7
RNActiQ8TEZ7 protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000170915 Expressed in globus pallidus and 185 other tissues
ExpressionAtlasiQ8TEZ7 baseline and differential
GenevisibleiQ8TEZ7 HS

Family and domain databases

InterProiView protein in InterPro
IPR004254 AdipoR/HlyIII-related
PANTHERiPTHR20855 PTHR20855, 1 hit
PfamiView protein in Pfam
PF03006 HlyIII, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPAQR8_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8TEZ7
Secondary accession number(s): B2RCF6
, Q86WL0, Q8N6D3, Q9HD02
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: June 1, 2002
Last modified: February 26, 2020
This is version 124 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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