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Entry version 136 (08 May 2019)
Sequence version 3 (18 May 2010)
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Protein

Neutral alpha-glucosidase C

Gene

GANC

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Has alpha-glucosidase activity.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose. EC:3.2.1.20

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei511NucleophilePROSITE-ProRule annotation1
Active sitei514By similarity1
Active sitei587Proton donorBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosidase, Hydrolase

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
GH31 Glycoside Hydrolase Family 31

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Neutral alpha-glucosidase C (EC:3.2.1.20)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GANC
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:4139 GANC

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
104180 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8TET4

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
2595

Open Targets

More...
OpenTargetsi
ENSG00000214013

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA28552

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL2520

Drug and drug target database

More...
DrugBanki
DB00491 Miglitol

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
GANC

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296439340

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001853641 – 914Neutral alpha-glucosidase CAdd BLAST914

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8TET4

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8TET4

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8TET4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8TET4

PeptideAtlas

More...
PeptideAtlasi
Q8TET4

PRoteomics IDEntifications database

More...
PRIDEi
Q8TET4

ProteomicsDB human proteome resource

More...
ProteomicsDBi
74496

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8TET4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8TET4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000214013 Expressed in 164 organ(s), highest expression level in corpus callosum

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8TET4 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8TET4 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA016949

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
108866, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q8TET4, 2 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000326227

Chemistry databases

BindingDB database of measured binding affinities

More...
BindingDBi
Q8TET4

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8TET4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyl hydrolase 31 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1066 Eukaryota
COG1501 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159230

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000115864

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8TET4

KEGG Orthology (KO)

More...
KOi
K12317

Identification of Orthologs from Complete Genome Data

More...
OMAi
KIHDKMG

Database of Orthologous Groups

More...
OrthoDBi
100626at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8TET4

TreeFam database of animal gene trees

More...
TreeFami
TF300337

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.1180, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011013 Gal_mutarotase_sf_dom
IPR000322 Glyco_hydro_31
IPR030458 Glyco_hydro_31_AS
IPR025887 Glyco_hydro_31_N_dom
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13802 Gal_mutarotas_2, 1 hit
PF01055 Glyco_hydro_31, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51445 SSF51445, 1 hit
SSF74650 SSF74650, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00129 GLYCOSYL_HYDROL_F31_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

Q8TET4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEAAVKEEIS LEDEAVDKNI FRDCNKIAFY RRQKQWLSKK STYQALLDSV
60 70 80 90 100
TTDEDSTRFQ IINEASKVPL LAEIYGIEGN IFRLKINEET PLKPRFEVPD
110 120 130 140 150
VLTSKPSTVR LISCSGDTGS LILADGKGDL KCHITANPFK VDLVSEEEVV
160 170 180 190 200
ISINSLGQLY FEHLQILHKQ RAAKENEEET SVDTSQENQE DLGLWEEKFG
210 220 230 240 250
KFVDIKANGP SSIGLDFSLH GFEHLYGIPQ HAESHQLKNT GDGDAYRLYN
260 270 280 290 300
LDVYGYQIYD KMGIYGSVPY LLAHKLGRTI GIFWLNASET LVEINTEPAV
310 320 330 340 350
EYTLTQMGPV AAKQKVRSRT HVHWMSESGI IDVFLLTGPT PSDVFKQYSH
360 370 380 390 400
LTGTQAMPPL FSLGYHQCRW NYEDEQDVKA VDAGFDEHDI PYDAMWLDIE
410 420 430 440 450
HTEGKRYFTW DKNRFPNPKR MQELLRSKKR KLVVISDPHI KIDPDYSVYV
460 470 480 490 500
KAKDQGFFVK NQEGEDFEGV CWPGLSSYLD FTNPKVREWY SSLFAFPVYQ
510 520 530 540 550
GSTDILFLWN DMNEPSVFRG PEQTMQKNAI HHGNWEHREL HNIYGFYHQM
560 570 580 590 600
ATAEGLIKRS KGKERPFVLT RSFFAGSQKY GAVWTGDNTA EWSNLKISIP
610 620 630 640 650
MLLTLSITGI SFCGADIGGF IGNPETELLV RWYQAGAYQP FFRGHATMNT
660 670 680 690 700
KRREPWLFGE EHTRLIREAI RERYGLLPYW YSLFYHAHVA SQPVMRPLWV
710 720 730 740 750
EFPDELKTFD MEDEYMLGSA LLVHPVTEPK ATTVDVFLPG SNEVWYDYKT
760 770 780 790 800
FAHWEGGCTV KIPVALDTIP VFQRGGSVIP IKTTVGKSTG WMTESSYGLR
810 820 830 840 850
VALSTKGSSV GELYLDDGHS FQYLHQKQFL HRKFSFCSSV LINSFADQRG
860 870 880 890 900
HYPSKCVVEK ILVLGFRKEP SSVTTHSSDG KDQPVAFTYC AKTSILSLEK
910
LSLNIATDWE VRII
Length:914
Mass (Da):104,334
Last modified:May 18, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7AA10E180DA7FDC2
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H3BN99H3BN99_HUMAN
Neutral alpha-glucosidase C
GANC
357Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E7EWB6E7EWB6_HUMAN
Neutral alpha-glucosidase C
GANC
282Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BMM3H3BMM3_HUMAN
Neutral alpha-glucosidase C
GANC
140Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BMW3H3BMW3_HUMAN
Neutral alpha-glucosidase C
GANC
67Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BRQ6H3BRQ6_HUMAN
Neutral alpha-glucosidase C
GANC
37Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JLA2A0A0G2JLA2_HUMAN
Neutral alpha-glucosidase C
GANC
9Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB84863 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti180T → A in AAO14993 (Ref. 5) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_01898411L → V3 PublicationsCorresponds to variant dbSNP:rs8043515Ensembl.1
Natural variantiVAR_01898544Q → R3 PublicationsCorresponds to variant dbSNP:rs8024732Ensembl.1
Natural variantiVAR_018986153I → M1 PublicationCorresponds to variant dbSNP:rs75876980Ensembl.1
Natural variantiVAR_056237166I → V. Corresponds to variant dbSNP:rs16973015Ensembl.1
Natural variantiVAR_018987443D → E1 PublicationCorresponds to variant dbSNP:rs2578652Ensembl.1
Natural variantiVAR_018988845F → S1 PublicationCorresponds to variant dbSNP:rs7181742Ensembl.1
Natural variantiVAR_018989848Q → R1 PublicationCorresponds to variant dbSNP:rs7180279Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF545044 mRNA Translation: AAN74755.1
AF545045 mRNA Translation: AAN74756.1
AF545046 mRNA Translation: AAN74757.1
AK074037 mRNA Translation: BAB84863.1 Different initiation.
AC012651 Genomic DNA No translation available.
AC022468 Genomic DNA No translation available.
BC059406 mRNA Translation: AAH59406.1
BC093833 mRNA Translation: AAH93833.1
AF525397 mRNA Translation: AAO14993.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS10084.1

NCBI Reference Sequences

More...
RefSeqi
NP_937784.2, NM_198141.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000318010; ENSP00000326227; ENSG00000214013

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2595

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:2595

UCSC genome browser

More...
UCSCi
uc001zpi.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF545044 mRNA Translation: AAN74755.1
AF545045 mRNA Translation: AAN74756.1
AF545046 mRNA Translation: AAN74757.1
AK074037 mRNA Translation: BAB84863.1 Different initiation.
AC012651 Genomic DNA No translation available.
AC022468 Genomic DNA No translation available.
BC059406 mRNA Translation: AAH59406.1
BC093833 mRNA Translation: AAH93833.1
AF525397 mRNA Translation: AAO14993.1
CCDSiCCDS10084.1
RefSeqiNP_937784.2, NM_198141.2

3D structure databases

SMRiQ8TET4
ModBaseiSearch...

Protein-protein interaction databases

BioGridi108866, 2 interactors
IntActiQ8TET4, 2 interactors
STRINGi9606.ENSP00000326227

Chemistry databases

BindingDBiQ8TET4
ChEMBLiCHEMBL2520
DrugBankiDB00491 Miglitol

Protein family/group databases

CAZyiGH31 Glycoside Hydrolase Family 31

PTM databases

iPTMnetiQ8TET4
PhosphoSitePlusiQ8TET4

Polymorphism and mutation databases

BioMutaiGANC
DMDMi296439340

Proteomic databases

EPDiQ8TET4
jPOSTiQ8TET4
MaxQBiQ8TET4
PaxDbiQ8TET4
PeptideAtlasiQ8TET4
PRIDEiQ8TET4
ProteomicsDBi74496

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
2595
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000318010; ENSP00000326227; ENSG00000214013
GeneIDi2595
KEGGihsa:2595
UCSCiuc001zpi.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
2595
DisGeNETi2595

GeneCards: human genes, protein and diseases

More...
GeneCardsi
GANC
HGNCiHGNC:4139 GANC
HPAiHPA016949
MIMi104180 gene
neXtProtiNX_Q8TET4
OpenTargetsiENSG00000214013
PharmGKBiPA28552

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1066 Eukaryota
COG1501 LUCA
GeneTreeiENSGT00940000159230
HOGENOMiHOG000115864
InParanoidiQ8TET4
KOiK12317
OMAiKIHDKMG
OrthoDBi100626at2759
PhylomeDBiQ8TET4
TreeFamiTF300337

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
GANC human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
GANC

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
2595

Protein Ontology

More...
PROi
PR:Q8TET4

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000214013 Expressed in 164 organ(s), highest expression level in corpus callosum
ExpressionAtlasiQ8TET4 baseline and differential
GenevisibleiQ8TET4 HS

Family and domain databases

Gene3Di2.60.40.1180, 2 hits
InterProiView protein in InterPro
IPR011013 Gal_mutarotase_sf_dom
IPR000322 Glyco_hydro_31
IPR030458 Glyco_hydro_31_AS
IPR025887 Glyco_hydro_31_N_dom
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
PfamiView protein in Pfam
PF13802 Gal_mutarotas_2, 1 hit
PF01055 Glyco_hydro_31, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit
SSF74650 SSF74650, 1 hit
PROSITEiView protein in PROSITE
PS00129 GLYCOSYL_HYDROL_F31_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGANC_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8TET4
Secondary accession number(s): Q52LQ4
, Q8IWZ0, Q8IZM4, Q8IZM5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: May 18, 2010
Last modified: May 8, 2019
This is version 136 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  6. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
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