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Protein

Taste receptor type 1 member 2

Gene

TAS1R2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • G protein-coupled receptor activity Source: GO_Central
  • protein heterodimerization activity Source: UniProtKB
  • taste receptor activity Source: UniProtKB

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer
Biological processSensory transduction, Taste

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-418594 G alpha (i) signalling events
R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors)

Protein family/group databases

Transport Classification Database

More...
TCDBi
9.A.14.7.4 the g-protein-coupled receptor (gpcr) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Taste receptor type 1 member 2
Alternative name(s):
G-protein coupled receptor 71
Sweet taste receptor T1R2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TAS1R2
Synonyms:GPR71, T1R2, TR2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000179002.5

Human Gene Nomenclature Database

More...
HGNCi
HGNC:14905 TAS1R2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
606226 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8TE23

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini20 – 566ExtracellularSequence analysisAdd BLAST547
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei567 – 587Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini588 – 602CytoplasmicSequence analysisAdd BLAST15
Transmembranei603 – 623Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini624 – 635ExtracellularSequence analysisAdd BLAST12
Transmembranei636 – 656Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini657 – 681CytoplasmicSequence analysisAdd BLAST25
Transmembranei682 – 702Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini703 – 727ExtracellularSequence analysisAdd BLAST25
Transmembranei728 – 748Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini749 – 760CytoplasmicSequence analysisAdd BLAST12
Transmembranei761 – 781Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini782 – 784ExtracellularSequence analysis3
Transmembranei785 – 805Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini806 – 839CytoplasmicSequence analysisAdd BLAST34

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
80834

Open Targets

More...
OpenTargetsi
ENSG00000179002

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37919

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL1613741

Drug and drug target database

More...
DrugBanki
DB00168 Aspartame

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TAS1R2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
116242831

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 19Sequence analysisAdd BLAST19
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001295720 – 839Taste receptor type 1 member 2Add BLAST820

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi84N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi248N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi292N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi312N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi368N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi428N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi487N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi527N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8TE23

PeptideAtlas

More...
PeptideAtlasi
Q8TE23

PRoteomics IDEntifications database

More...
PRIDEi
Q8TE23

ProteomicsDB human proteome resource

More...
ProteomicsDBi
74391

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8TE23

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8TE23

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000179002 Expressed in 2 organ(s), highest expression level in skin of leg

CleanEx database of gene expression profiles

More...
CleanExi
HS_TAS1R2

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8TE23 HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Forms heterodimers with TAS1R3.

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
123327, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000364520

Chemistry databases

BindingDB database of measured binding affinities

More...
BindingDBi
Q8TE23

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q8TE23

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1056 Eukaryota
ENOG410XR6W LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156136

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000038047

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG108601

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8TE23

KEGG Orthology (KO)

More...
KOi
K04625

Identification of Orthologs from Complete Genome Data

More...
OMAi
CCFECID

Database of Orthologous Groups

More...
OrthoDBi
EOG091G035J

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8TE23

TreeFam database of animal gene trees

More...
TreeFami
TF331269

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.10.50.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001828 ANF_lig-bd_rcpt
IPR000337 GPCR_3
IPR011500 GPCR_3_9-Cys_dom
IPR038550 GPCR_3_9-Cys_sf
IPR017978 GPCR_3_C
IPR000068 GPCR_3_Ca_sens_rcpt-rel
IPR017979 GPCR_3_CS
IPR028082 Peripla_BP_I

The PANTHER Classification System

More...
PANTHERi
PTHR24061 PTHR24061, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00003 7tm_3, 1 hit
PF01094 ANF_receptor, 1 hit
PF07562 NCD3G, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00248 GPCRMGR

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53822 SSF53822, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00980 G_PROTEIN_RECEP_F3_2, 1 hit
PS50259 G_PROTEIN_RECEP_F3_4, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q8TE23-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGPRAKTISS LFFLLWVLAE PAENSDFYLP GDYLLGGLFS LHANMKGIVH
60 70 80 90 100
LNFLQVPMCK EYEVKVIGYN LMQAMRFAVE EINNDSSLLP GVLLGYEIVD
110 120 130 140 150
VCYISNNVQP VLYFLAHEDN LLPIQEDYSN YISRVVAVIG PDNSESVMTV
160 170 180 190 200
ANFLSLFLLP QITYSAISDE LRDKVRFPAL LRTTPSADHH IEAMVQLMLH
210 220 230 240 250
FRWNWIIVLV SSDTYGRDNG QLLGERVARR DICIAFQETL PTLQPNQNMT
260 270 280 290 300
SEERQRLVTI VDKLQQSTAR VVVVFSPDLT LYHFFNEVLR QNFTGAVWIA
310 320 330 340 350
SESWAIDPVL HNLTELRHLG TFLGITIQSV PIPGFSEFRE WGPQAGPPPL
360 370 380 390 400
SRTSQSYTCN QECDNCLNAT LSFNTILRLS GERVVYSVYS AVYAVAHALH
410 420 430 440 450
SLLGCDKSTC TKRVVYPWQL LEEIWKVNFT LLDHQIFFDP QGDVALHLEI
460 470 480 490 500
VQWQWDRSQN PFQSVASYYP LQRQLKNIQD ISWHTINNTI PMSMCSKRCQ
510 520 530 540 550
SGQKKKPVGI HVCCFECIDC LPGTFLNHTE DEYECQACPN NEWSYQSETS
560 570 580 590 600
CFKRQLVFLE WHEAPTIAVA LLAALGFLST LAILVIFWRH FQTPIVRSAG
610 620 630 640 650
GPMCFLMLTL LLVAYMVVPV YVGPPKVSTC LCRQALFPLC FTICISCIAV
660 670 680 690 700
RSFQIVCAFK MASRFPRAYS YWVRYQGPYV SMAFITVLKM VIVVIGMLAT
710 720 730 740 750
GLSPTTRTDP DDPKITIVSC NPNYRNSLLF NTSLDLLLSV VGFSFAYMGK
760 770 780 790 800
ELPTNYNEAK FITLSMTFYF TSSVSLCTFM SAYSGVLVTI VDLLVTVLNL
810 820 830
LAISLGYFGP KCYMILFYPE RNTPAYFNSM IQGYTMRRD
Length:839
Mass (Da):95,183
Last modified:October 17, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA7F73516489A05F9
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0279019S → C1 PublicationCorresponds to variant dbSNP:rs9701796Ensembl.1
Natural variantiVAR_061199191I → V1 PublicationCorresponds to variant dbSNP:rs35874116Ensembl.1
Natural variantiVAR_061200317R → G1 PublicationCorresponds to variant dbSNP:rs34447754Ensembl.1
Natural variantiVAR_061201486I → V1 PublicationCorresponds to variant dbSNP:rs28374389Ensembl.1
Natural variantiVAR_020787574A → T. Corresponds to variant dbSNP:rs6662276Ensembl.1
Natural variantiVAR_061202595I → T. Corresponds to variant dbSNP:rs41273167Ensembl.1
Natural variantiVAR_027902838R → K. Corresponds to variant dbSNP:rs9988418Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF458154
, AF458149, AF458150, AF458152, AF458153, AF458151 Genomic DNA Translation: AAM12239.1
BX537160 Genomic DNA No translation available.
AL831755 Genomic DNA No translation available.
BK000151 Genomic DNA Translation: DAA00019.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS187.1

NCBI Reference Sequences

More...
RefSeqi
NP_689418.2, NM_152232.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.553548

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000375371; ENSP00000364520; ENSG00000179002

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
80834

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:80834

UCSC genome browser

More...
UCSCi
uc001bba.2 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Protein Spotlight

The taste experience - Issue 55 of February 2005

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF458154
, AF458149, AF458150, AF458152, AF458153, AF458151 Genomic DNA Translation: AAM12239.1
BX537160 Genomic DNA No translation available.
AL831755 Genomic DNA No translation available.
BK000151 Genomic DNA Translation: DAA00019.1
CCDSiCCDS187.1
RefSeqiNP_689418.2, NM_152232.2
UniGeneiHs.553548

3D structure databases

ProteinModelPortaliQ8TE23
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi123327, 1 interactor
STRINGi9606.ENSP00000364520

Chemistry databases

BindingDBiQ8TE23
ChEMBLiCHEMBL1613741
DrugBankiDB00168 Aspartame

Protein family/group databases

TCDBi9.A.14.7.4 the g-protein-coupled receptor (gpcr) family

Information system for G protein-coupled receptors (GPCRs)

More...
GPCRDBi
Search...

PTM databases

iPTMnetiQ8TE23
PhosphoSitePlusiQ8TE23

Polymorphism and mutation databases

BioMutaiTAS1R2
DMDMi116242831

Proteomic databases

PaxDbiQ8TE23
PeptideAtlasiQ8TE23
PRIDEiQ8TE23
ProteomicsDBi74391

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
80834
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000375371; ENSP00000364520; ENSG00000179002
GeneIDi80834
KEGGihsa:80834
UCSCiuc001bba.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80834
DisGeNETi80834
EuPathDBiHostDB:ENSG00000179002.5

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TAS1R2
HGNCiHGNC:14905 TAS1R2
MIMi606226 gene
neXtProtiNX_Q8TE23
OpenTargetsiENSG00000179002
PharmGKBiPA37919

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1056 Eukaryota
ENOG410XR6W LUCA
GeneTreeiENSGT00940000156136
HOGENOMiHOG000038047
HOVERGENiHBG108601
InParanoidiQ8TE23
KOiK04625
OMAiCCFECID
OrthoDBiEOG091G035J
PhylomeDBiQ8TE23
TreeFamiTF331269

Enzyme and pathway databases

ReactomeiR-HSA-418594 G alpha (i) signalling events
R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors)

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
TAS1R2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
80834

Protein Ontology

More...
PROi
PR:Q8TE23

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000179002 Expressed in 2 organ(s), highest expression level in skin of leg
CleanExiHS_TAS1R2
GenevisibleiQ8TE23 HS

Family and domain databases

Gene3Di2.10.50.30, 1 hit
InterProiView protein in InterPro
IPR001828 ANF_lig-bd_rcpt
IPR000337 GPCR_3
IPR011500 GPCR_3_9-Cys_dom
IPR038550 GPCR_3_9-Cys_sf
IPR017978 GPCR_3_C
IPR000068 GPCR_3_Ca_sens_rcpt-rel
IPR017979 GPCR_3_CS
IPR028082 Peripla_BP_I
PANTHERiPTHR24061 PTHR24061, 1 hit
PfamiView protein in Pfam
PF00003 7tm_3, 1 hit
PF01094 ANF_receptor, 1 hit
PF07562 NCD3G, 1 hit
PRINTSiPR00248 GPCRMGR
SUPFAMiSSF53822 SSF53822, 1 hit
PROSITEiView protein in PROSITE
PS00980 G_PROTEIN_RECEP_F3_2, 1 hit
PS50259 G_PROTEIN_RECEP_F3_4, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTS1R2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8TE23
Secondary accession number(s): Q5TZ19
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: October 17, 2006
Last modified: December 5, 2018
This is version 148 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  6. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  7. Protein Spotlight
    Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
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