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UniProtKB - Q8TDV2 (GP148_HUMAN)

Entry version 123 (07 Apr 2021)
Sequence version 2 (02 Nov 2010)
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Protein

Probable G-protein coupled receptor 148

Gene

GPR148

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Orphan receptor.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q8TDV2

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable G-protein coupled receptor 148
Alternative name(s):
Brain and testis restricted GPCR
G-protein coupled receptor PGR6
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GPR148
Synonyms:BTR, PGR6
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:23623, GPR148

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q8TDV2

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000173302.5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 51ExtracellularSequence analysisAdd BLAST51
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei52 – 72Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini73 – 85CytoplasmicSequence analysisAdd BLAST13
Transmembranei86 – 106Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini107 – 130ExtracellularSequence analysisAdd BLAST24
Transmembranei131 – 151Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini152 – 165CytoplasmicSequence analysisAdd BLAST14
Transmembranei166 – 186Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini187 – 214ExtracellularSequence analysisAdd BLAST28
Transmembranei215 – 235Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini236 – 261CytoplasmicSequence analysisAdd BLAST26
Transmembranei262 – 282Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini283 – 299ExtracellularSequence analysisAdd BLAST17
Transmembranei300 – 322Helical; Name=7Sequence analysisAdd BLAST23
Topological domaini323 – 347CytoplasmicSequence analysisAdd BLAST25

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000173302

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134942667

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q8TDV2, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		GPR148

Domain mapping of disease mutations (DMDM)

More...DMDMi		311033389

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000696251 – 347Probable G-protein coupled receptor 148Add BLAST347

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi34N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8TDV2

PeptideAtlas

More...PeptideAtlasi		Q8TDV2

PRoteomics IDEntifications database

More...PRIDEi		Q8TDV2

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		74343

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q8TDV2, 1 site

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8TDV2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8TDV2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expression restricted to nervous system and testis. Is also detected in several tumors types, most notably prostate cancer.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000173302, Expressed in islet of Langerhans and 14 other tissues

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000173302, Group enriched (brain, pancreas, pituitary gland, stomach)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		131308, 1 interactor

Protein interaction database and analysis system

More...IntActi		Q8TDV2, 1 interactor

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000308908

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8TDV2, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi107 – 110Poly-Ser4

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3656, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT01020000230341

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_067256_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8TDV2

Identification of Orthologs from Complete Genome Data

More...OMAi		HIDSGTH

Database of Orthologous Groups

More...OrthoDBi		1419205at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8TDV2

TreeFam database of animal gene trees

More...TreeFami		TF333617

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000276, GPCR_Rhodpsn
IPR017452, GPCR_Rhodpsn_7TM

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00001, 7tm_1, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50262, G_PROTEIN_RECEP_F1_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8TDV2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGDELAPCPV GTTAWPALIQ LISKTPCMPQ AASNTSLGLG DLRVPSSMLY 
        60         70         80         90        100
WLFLPSSLLA AATLAVSPLL LVTILRNQRL RQEPHYLLPA NILLSDLAYI 
       110        120        130        140        150
LLHMLISSSS LGGWELGRMA CGILTDAVFA ACTSTILSFT AIVLHTYLAV 
       160        170        180        190        200
IHPLRYLSFM SHGAAWKAVA LIWLVACCFP TFLIWLSKWQ DAQLEEQGAS 
       210        220        230        240        250
YILPPSMGTQ PGCGLLVIVT YTSILCVLFL CTALIANCFW RIYAEAKTSG 
       260        270        280        290        300
IWGQGYSRAR GTLLIHSVLI TLYVSTGVVF SLDMVLTRYH HIDSGTHTWL 
       310        320        330        340 
LAANSEVLMM LPRAMLTYLY LLRYRQLLGM VRGHLPSRRH QAIFTIS
Length:347
Mass (Da):38,288
Last modified:November 2, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEA2ECACE2BD542A8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti27 – 62CMPQA…LLAAA → SS in AAP34196 (PubMed:15688318).CuratedAdd BLAST36
Sequence conflicti130A → D in AAP34196 (PubMed:15688318).Curated1
Sequence conflicti138S → F in AAP34196 (PubMed:15688318).Curated1
Sequence conflicti141A → G in AAP34196 (PubMed:15688318).Curated1
Sequence conflicti155R → G in AAP34196 (PubMed:15688318).Curated1
Sequence conflicti168A → P in AAP34196 (PubMed:15688318).Curated1
Sequence conflicti171L → F in AAP34196 (PubMed:15688318).Curated1
Sequence conflicti199A → V in AAP34196 (PubMed:15688318).Curated1
Sequence conflicti215L → F in AAP34196 (PubMed:15688318).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_049403317T → P4 PublicationsCorresponds to variant dbSNP:rs272128Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB083589 Genomic DNA Translation: BAB89302.1
AY280965 mRNA Translation: AAP34196.1
AY569570 mRNA Translation: AAS76892.1
AC140481 Genomic DNA No translation available.
BC105013 mRNA Translation: AAI05014.1
BC105041 mRNA Translation: AAI05042.1
AY255532 mRNA Translation: AAO85044.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS2163.1

NCBI Reference Sequences

More...RefSeqi		NP_997247.2, NM_207364.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000309926; ENSP00000308908; ENSG00000173302

Database of genes from NCBI RefSeq genomes

More...GeneIDi		344561

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:344561

UCSC genome browser

More...UCSCi		uc002trv.2, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB083589 Genomic DNA Translation: BAB89302.1
AY280965 mRNA Translation: AAP34196.1
AY569570 mRNA Translation: AAS76892.1
AC140481 Genomic DNA No translation available.
BC105013 mRNA Translation: AAI05014.1
BC105041 mRNA Translation: AAI05042.1
AY255532 mRNA Translation: AAO85044.1
CCDSiCCDS2163.1
RefSeqiNP_997247.2, NM_207364.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi131308, 1 interactor
IntActiQ8TDV2, 1 interactor
STRINGi9606.ENSP00000308908

Protein family/group databases

Information system for G protein-coupled receptors (GPCRs)

More...GPCRDBi		Search...

PTM databases

GlyGeniQ8TDV2, 1 site
iPTMnetiQ8TDV2
PhosphoSitePlusiQ8TDV2

Genetic variation databases

BioMutaiGPR148
DMDMi311033389

Proteomic databases

PaxDbiQ8TDV2
PeptideAtlasiQ8TDV2
PRIDEiQ8TDV2
ProteomicsDBi74343

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		18608, 56 antibodies

The DNASU plasmid repository

More...DNASUi		344561

Genome annotation databases

EnsembliENST00000309926; ENSP00000308908; ENSG00000173302
GeneIDi344561
KEGGihsa:344561
UCSCiuc002trv.2, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		344561

GeneCards: human genes, protein and diseases

More...GeneCardsi		GPR148
HGNCiHGNC:23623, GPR148
HPAiENSG00000173302, Group enriched (brain, pancreas, pituitary gland, stomach)
neXtProtiNX_Q8TDV2
OpenTargetsiENSG00000173302
PharmGKBiPA134942667
VEuPathDBiHostDB:ENSG00000173302.5

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3656, Eukaryota
GeneTreeiENSGT01020000230341
HOGENOMiCLU_067256_0_0_1
InParanoidiQ8TDV2
OMAiHIDSGTH
OrthoDBi1419205at2759
PhylomeDBiQ8TDV2
TreeFamiTF333617

Enzyme and pathway databases

PathwayCommonsiQ8TDV2

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		344561, 2 hits in 976 CRISPR screens

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		GPR148

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		344561
PharosiQ8TDV2, Tdark

Protein Ontology

More...PROi		PR:Q8TDV2
RNActiQ8TDV2, protein

Gene expression databases

BgeeiENSG00000173302, Expressed in islet of Langerhans and 14 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR000276, GPCR_Rhodpsn
IPR017452, GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001, 7tm_1, 1 hit
PROSITEiView protein in PROSITE
PS50262, G_PROTEIN_RECEP_F1_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGP148_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8TDV2
Secondary accession number(s): Q2M369, Q86SP7, Q86U87
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: November 2, 2010
Last modified: April 7, 2021
This is version 123 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  3. Human entries with genetic variants
    List of human entries with genetic variants
  4. Human variants curated from literature reports
    Index of human variants curated from literature reports
  5. SIMILARITY comments
    Index of protein domains and families
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