Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Secretoglobin family 1C member 1

Gene

SCGB1C1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Secretoglobin family 1C member 1
Alternative name(s):
Secretoglobin RYD5
Gene namesi
Name:SCGB1C1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000188076.2
HGNCiHGNC:18394 SCGB1C1
MIMi610176 gene
neXtProtiNX_Q8TD33

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Organism-specific databases

DisGeNETi147199
653486
OpenTargetsiENSG00000188076

Polymorphism and mutation databases

BioMutaiSCGB1C1
DMDMi296452904

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000022333224 – 95Secretoglobin family 1C member 1Add BLAST72

Proteomic databases

PaxDbiQ8TD33
PRIDEiQ8TD33
ProteomicsDBi74230

PTM databases

iPTMnetiQ8TD33
PhosphoSitePlusiQ8TD33

Expressioni

Gene expression databases

BgeeiENSG00000188076 Expressed in 46 organ(s), highest expression level in body of pancreas
CleanExiHS_SCGB1C1
GenevisibleiQ8TD33 HS

Structurei

3D structure databases

ProteinModelPortaliQ8TD33
SMRiQ8TD33
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the secretoglobin family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410J2P6 Eukaryota
ENOG4111BH3 LUCA
GeneTreeiENSGT00390000016583
HOGENOMiHOG000220914
HOVERGENiHBG098533
InParanoidiQ8TD33
OMAiFFMEFLQ
OrthoDBiEOG091G17VD
PhylomeDBiQ8TD33
TreeFamiTF337061

Family and domain databases

CDDicd00633 Secretoglobin, 1 hit
InterProiView protein in InterPro
IPR016126 Secretoglobin
IPR028659 Secretoglobin_1C1/2
IPR035960 Secretoglobin_sf
PANTHERiPTHR10136:SF8 PTHR10136:SF8, 1 hit
PfamiView protein in Pfam
PF01099 Uteroglobin, 1 hit
SUPFAMiSSF48201 SSF48201, 1 hit
PROSITEiView protein in PROSITE
PS51311 SCGB, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8TD33-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKGSRALLLV ALTLFCICRM ATGEDNDEFF MDFLQTLLVG TPEELYEGTL
60 70 80 90
GKYNVNEDAK AAMTELKSCI DGLQPMHKAE LVKLLVQVLG SQDGA
Length:95
Mass (Da):10,414
Last modified:May 18, 2010 - v2
Checksum:iF6331EADC96D2392
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_06310270I → R3 PublicationsCorresponds to variant dbSNP:rs2686894Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY026938 mRNA Translation: AAK08972.1
AC069287 Genomic DNA No translation available.
BC069287 mRNA Translation: AAH69287.1
BC111427 mRNA Translation: AAI11428.1
BC111433 mRNA Translation: AAI11434.1
BK000201 mRNA Translation: DAA00358.1
CCDSiCCDS41581.1
RefSeqiNP_001091079.1, NM_001097610.2
NP_663626.2, NM_145651.2
UniGeneiHs.127059

Genome annotation databases

EnsembliENST00000342878; ENSP00000344545; ENSG00000188076
GeneIDi147199
653486
KEGGihsa:147199
hsa:653486
UCSCiuc001loa.1 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY026938 mRNA Translation: AAK08972.1
AC069287 Genomic DNA No translation available.
BC069287 mRNA Translation: AAH69287.1
BC111427 mRNA Translation: AAI11428.1
BC111433 mRNA Translation: AAI11434.1
BK000201 mRNA Translation: DAA00358.1
CCDSiCCDS41581.1
RefSeqiNP_001091079.1, NM_001097610.2
NP_663626.2, NM_145651.2
UniGeneiHs.127059

3D structure databases

ProteinModelPortaliQ8TD33
SMRiQ8TD33
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiQ8TD33
PhosphoSitePlusiQ8TD33

Polymorphism and mutation databases

BioMutaiSCGB1C1
DMDMi296452904

Proteomic databases

PaxDbiQ8TD33
PRIDEiQ8TD33
ProteomicsDBi74230

Protocols and materials databases

DNASUi147199
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000342878; ENSP00000344545; ENSG00000188076
GeneIDi147199
653486
KEGGihsa:147199
hsa:653486
UCSCiuc001loa.1 human

Organism-specific databases

CTDi147199
653486
DisGeNETi147199
653486
EuPathDBiHostDB:ENSG00000188076.2
GeneCardsiSCGB1C1
H-InvDBiHIX0201712
HGNCiHGNC:18394 SCGB1C1
MIMi610176 gene
neXtProtiNX_Q8TD33
OpenTargetsiENSG00000188076
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410J2P6 Eukaryota
ENOG4111BH3 LUCA
GeneTreeiENSGT00390000016583
HOGENOMiHOG000220914
HOVERGENiHBG098533
InParanoidiQ8TD33
OMAiFFMEFLQ
OrthoDBiEOG091G17VD
PhylomeDBiQ8TD33
TreeFamiTF337061

Miscellaneous databases

ChiTaRSiSCGB1C1 human
PROiPR:Q8TD33
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000188076 Expressed in 46 organ(s), highest expression level in body of pancreas
CleanExiHS_SCGB1C1
GenevisibleiQ8TD33 HS

Family and domain databases

CDDicd00633 Secretoglobin, 1 hit
InterProiView protein in InterPro
IPR016126 Secretoglobin
IPR028659 Secretoglobin_1C1/2
IPR035960 Secretoglobin_sf
PANTHERiPTHR10136:SF8 PTHR10136:SF8, 1 hit
PfamiView protein in Pfam
PF01099 Uteroglobin, 1 hit
SUPFAMiSSF48201 SSF48201, 1 hit
PROSITEiView protein in PROSITE
PS51311 SCGB, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSG1C1_HUMAN
AccessioniPrimary (citable) accession number: Q8TD33
Secondary accession number(s): A8MSI9, Q14DW0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: May 18, 2010
Last modified: September 12, 2018
This is version 121 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again