SCGB1C1

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Secretoglobin family 1C member 1 Alternative name(s): Secretoglobin RYD5
Gene namesⁱ	Name:SCGB1C1
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 11

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000188076.2
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:18394 SCGB1C1
MIMⁱ	610176 gene
neXtProtⁱ	NX_Q8TD33

Keywords - Cellular componentⁱ

Secreted

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	147199 653486
Open Targets More...OpenTargetsⁱ	ENSG00000188076

Polymorphism and mutation databases

BioMutaⁱ	SCGB1C1
DMDMⁱ	296452904

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 23	Sequence analysisAdd BLAST		23
ChainⁱPRO_0000223332	24 – 95	Secretoglobin family 1C member 1Add BLAST		72

Proteomic databases

PaxDbⁱ	Q8TD33
PRIDEⁱ	Q8TD33
ProteomicsDBⁱ	74230

PTM databases

iPTMnetⁱ	Q8TD33
PhosphoSitePlusⁱ	Q8TD33

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000188076 Expressed in 46 organ(s), highest expression level in body of pancreas
CleanExⁱ	HS_SCGB1C1
Genevisibleⁱ	Q8TD33 HS

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q8TD33
SMRⁱ	Q8TD33
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the secretoglobin family.Curated

Keywords - Domainⁱ

Signal

Phylogenomic databases

eggNOGⁱ	ENOG410J2P6 Eukaryota ENOG4111BH3 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000016583
HOGENOMⁱ	HOG000220914
HOVERGENⁱ	HBG098533
InParanoidⁱ	Q8TD33
OMAⁱ	FFMEFLQ
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G17VD
PhylomeDBⁱ	Q8TD33
TreeFamⁱ	TF337061

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00633 Secretoglobin, 1 hit
InterProⁱ	View protein in InterPro IPR016126 Secretoglobin IPR028659 Secretoglobin_1C1/2 IPR035960 Secretoglobin_sf
PANTHERⁱ	PTHR10136:SF8 PTHR10136:SF8, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01099 Uteroglobin, 1 hit
SUPFAMⁱ	SSF48201 SSF48201, 1 hit
PROSITEⁱ	View protein in PROSITE PS51311 SCGB, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

Q8TD33-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MKGSRALLLV ALTLFCICRM ATGEDNDEFF MDFLQTLLVG TPEELYEGTL 
        60         70         80         90 
GKYNVNEDAK AAMTELKSCI DGLQPMHKAE LVKLLVQVLG SQDGA

Length:95

Mass (Da):10,414

Last modified:May 18, 2010 - v2

Checksum:ⁱF6331EADC96D2392

GO

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_063102	70	I → R3 PublicationsCorresponds to variant dbSNP:rs2686894Ensembl.		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AY026938 mRNA Translation: AAK08972.1 AC069287 Genomic DNA No translation available. BC069287 mRNA Translation: AAH69287.1 BC111427 mRNA Translation: AAI11428.1 BC111433 mRNA Translation: AAI11434.1 BK000201 mRNA Translation: DAA00358.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS41581.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001091079.1, NM_001097610.2 NP_663626.2, NM_145651.2
UniGeneⁱ	Hs.127059

Genome annotation databases

Ensemblⁱ	ENST00000342878; ENSP00000344545; ENSG00000188076
GeneIDⁱ	147199 653486
KEGGⁱ	hsa:147199 hsa:653486
UCSC genome browser More...UCSCⁱ	uc001loa.1 human

Keywords - Coding sequence diversityⁱ

Polymorphism

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q8TD33	Secretoglobin family 1C member 2		HUMAN		95	UniRef90_Q8TD33
UPI0005CFF4C6		HUMAN		138
UPI0005D0073C		HUMAN		138

Protein	Similar proteins		Species	Score	Length	Source
Q8TD33	Secretoglobin family 1C member 2		HUMAN		95	UniRef50_Q8TD33
LOW QUALITY PROTEIN: secretoglobin family 1C member 1		PHYCD		162
UPI0005CFF4C6		HUMAN		138
UPI0005D0073C		HUMAN		138

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AY026938 mRNA Translation: AAK08972.1 AC069287 Genomic DNA No translation available. BC069287 mRNA Translation: AAH69287.1 BC111427 mRNA Translation: AAI11428.1 BC111433 mRNA Translation: AAI11434.1 BK000201 mRNA Translation: DAA00358.1
CCDSⁱ	CCDS41581.1
RefSeqⁱ	NP_001091079.1, NM_001097610.2 NP_663626.2, NM_145651.2
UniGeneⁱ	Hs.127059

3D structure databases

ProteinModelPortalⁱ	Q8TD33
SMRⁱ	Q8TD33
ModBaseⁱ	Search...
MobiDBⁱ	Search...

PTM databases

iPTMnetⁱ	Q8TD33
PhosphoSitePlusⁱ	Q8TD33

Polymorphism and mutation databases

BioMutaⁱ	SCGB1C1
DMDMⁱ	296452904

Proteomic databases

PaxDbⁱ	Q8TD33
PRIDEⁱ	Q8TD33
ProteomicsDBⁱ	74230

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	147199
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000342878; ENSP00000344545; ENSG00000188076
GeneIDⁱ	147199 653486
KEGGⁱ	hsa:147199 hsa:653486
UCSCⁱ	uc001loa.1 human

Organism-specific databases

CTDⁱ	147199 653486
DisGeNETⁱ	147199 653486
EuPathDBⁱ	HostDB:ENSG00000188076.2
GeneCardsⁱ	SCGB1C1
H-InvDBⁱ	HIX0201712
HGNCⁱ	HGNC:18394 SCGB1C1
MIMⁱ	610176 gene
neXtProtⁱ	NX_Q8TD33
OpenTargetsⁱ	ENSG00000188076
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410J2P6 Eukaryota ENOG4111BH3 LUCA
GeneTreeⁱ	ENSGT00390000016583
HOGENOMⁱ	HOG000220914
HOVERGENⁱ	HBG098533
InParanoidⁱ	Q8TD33
OMAⁱ	FFMEFLQ
OrthoDBⁱ	EOG091G17VD
PhylomeDBⁱ	Q8TD33
TreeFamⁱ	TF337061

Miscellaneous databases

ChiTaRSⁱ	SCGB1C1 human
Protein Ontology More...PROⁱ	PR:Q8TD33
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000188076 Expressed in 46 organ(s), highest expression level in body of pancreas
CleanExⁱ	HS_SCGB1C1
Genevisibleⁱ	Q8TD33 HS

Family and domain databases

CDDⁱ	cd00633 Secretoglobin, 1 hit
InterProⁱ	View protein in InterPro IPR016126 Secretoglobin IPR028659 Secretoglobin_1C1/2 IPR035960 Secretoglobin_sf
PANTHERⁱ	PTHR10136:SF8 PTHR10136:SF8, 1 hit
Pfamⁱ	View protein in Pfam PF01099 Uteroglobin, 1 hit
SUPFAMⁱ	SSF48201 SSF48201, 1 hit
PROSITEⁱ	View protein in PROSITE PS51311 SCGB, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	SG1C1_HUMAN
Accessionⁱ	Q8TD33Primary (citable) accession number: Q8TD33 Secondary accession number(s): A8MSI9, Q14DW0
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	February 21, 2006
	Last sequence update:	May 18, 2010
	Last modified:	September 12, 2018
	This is version 121 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
SIMILARITY comments
Index of protein domains and families
Human chromosome 11
Human chromosome 11: entries, gene names and cross-references to MIM
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q8TD33 (SG1C1_HUMAN)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Secretoglobin family 1C member 1

Select a section on the left to see content.

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted

Extracellular region or secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Natural variant

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ