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Entry version 125 (12 Aug 2020)
Sequence version 1 (01 Jun 2002)
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Protein

Solute carrier family 7 member 13

Gene

SLC7A13

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAmino-acid transport, Transport

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q8TCU3

Protein family/group databases

Transport Classification Database

More...
TCDBi
2.A.3.8.24, the amino acid-polyamine-organocation (apc) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Solute carrier family 7 member 13
Alternative name(s):
Sodium-independent aspartate/glutamate transporter 1
X-amino acid transporter 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SLC7A13
Synonyms:AGT1, XAT2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000164893.8

Human Gene Nomenclature Database

More...
HGNCi
HGNC:23092, SLC7A13

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
617256, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8TCU3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 11CytoplasmicSequence analysisAdd BLAST11
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei12 – 32Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini33 – 45ExtracellularSequence analysisAdd BLAST13
Transmembranei46 – 66Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini67 – 87CytoplasmicSequence analysisAdd BLAST21
Transmembranei88 – 108Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini109 – 128ExtracellularSequence analysisAdd BLAST20
Transmembranei129 – 149Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini150 – 162CytoplasmicSequence analysisAdd BLAST13
Transmembranei163 – 183Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini184 – 206ExtracellularSequence analysisAdd BLAST23
Transmembranei207 – 227Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini228 – 240CytoplasmicSequence analysisAdd BLAST13
Transmembranei241 – 261Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini262 – 287ExtracellularSequence analysisAdd BLAST26
Transmembranei288 – 308Helical; Name=8Sequence analysisAdd BLAST21
Topological domaini309 – 336CytoplasmicSequence analysisAdd BLAST28
Transmembranei337 – 357Helical; Name=9Sequence analysisAdd BLAST21
Topological domaini358ExtracellularSequence analysis1
Transmembranei359 – 379Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini380 – 393CytoplasmicSequence analysisAdd BLAST14
Transmembranei394 – 414Helical; Name=11Sequence analysisAdd BLAST21
Topological domaini415 – 421ExtracellularSequence analysis7
Transmembranei422 – 442Helical; Name=12Sequence analysisAdd BLAST21
Topological domaini443 – 470CytoplasmicSequence analysisAdd BLAST28

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
157724

Open Targets

More...
OpenTargetsi
ENSG00000164893

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134980828

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8TCU3, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SLC7A13

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74751412

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003307251 – 470Solute carrier family 7 member 13Add BLAST470

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8TCU3

PeptideAtlas

More...
PeptideAtlasi
Q8TCU3

PRoteomics IDEntifications database

More...
PRIDEi
Q8TCU3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
74169 [Q8TCU3-1]
74170 [Q8TCU3-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8TCU3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8TCU3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in the kidney.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000164893, Expressed in kidney epithelium and 36 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8TCU3, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000164893, Tissue enriched (kidney)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
127618, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q8TCU3, 2 interactors

Molecular INTeraction database

More...
MINTi
Q8TCU3

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000297524

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8TCU3, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1287, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162798

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_007946_3_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8TCU3

KEGG Orthology (KO)

More...
KOi
K13870

Identification of Orthologs from Complete Genome Data

More...
OMAi
KSPNVHY

Database of Orthologous Groups

More...
OrthoDBi
621852at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8TCU3

TreeFam database of animal gene trees

More...
TreeFami
TF313355

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002293, AA/rel_permease1

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13520, AA_permease_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q8TCU3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDRGEKIQLK RVFGYWWGTS FLLINIIGAG IFVSPKGVLA YSCMNVGVSL
60 70 80 90 100
CVWAGCAILA MTSTLCSAEI SISFPCSGAQ YYFLKRYFGS TVAFLNLWTS
110 120 130 140 150
LFLGSGVVAG QALLLAEYSI QPFFPSCSVP KLPKKCLALA MLWIVGILTS
160 170 180 190 200
RGVKEVTWLQ IASSVLKVSI LSFISLTGVV FLIRGKKENV ERFQNAFDAE
210 220 230 240 250
LPDISHLIQA IFQGYFAYSG GACFTLIAGE LKKPRTTIPK CIFTALPLVT
260 270 280 290 300
VVYLLVNISY LTVLTPREIL SSDAVAITWA DRAFPSLAWI MPFAISTSLF
310 320 330 340 350
SNLLISIFKS SRPIYLASQE GQLPLLFNTL NSHSSPFTAV LLLVTLGSLA
360 370 380 390 400
IILTSLIDLI NYIFFTGSLW SILLMIGILR RRYQEPNLSI PYKVFLSFPL
410 420 430 440 450
ATIVIDVGLV VIPLVKSPNV HYVYVLLLVL SGLLFYIPLI HFKIRLAWFE
460 470
KMTCYLQLLF NICLPDVSEE
Length:470
Mass (Da):52,114
Last modified:June 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF8593B829E2050E7
GO
Isoform 2 (identifier: Q8TCU3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     221-229: Missing.
     394-442: VFLSFPLATI...LLFYIPLIHF → SLILVVQAGE...WDYRCFCHFH
     443-470: Missing.

Show »
Length:433
Mass (Da):48,002
Checksum:i98A7ADEA5CF284E2
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_042716249V → M2 PublicationsCorresponds to variant dbSNP:rs2976189Ensembl.1
Natural variantiVAR_042717380R → K. Corresponds to variant dbSNP:rs4419794Ensembl.1
Natural variantiVAR_042718452M → T. Corresponds to variant dbSNP:rs9656982Ensembl.1
Natural variantiVAR_042719470E → K. Corresponds to variant dbSNP:rs9693999Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_033067221 – 229Missing in isoform 2. 1 Publication9
Alternative sequenceiVSP_033068394 – 442VFLSF…PLIHF → SLILVVQAGEAGVQWHDLGL LQPLLPGFKRFSCLSLPSSW DYRCFCHFH in isoform 2. 1 PublicationAdd BLAST49
Alternative sequenceiVSP_033069443 – 470Missing in isoform 2. 1 PublicationAdd BLAST28

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ417661 mRNA Translation: CAD10393.1
AK055815 mRNA Translation: BAB71021.1
CH471060 Genomic DNA Translation: EAW91633.1
BC125165 mRNA Translation: AAI25166.1
BC125166 mRNA Translation: AAI25167.1
BC029436 mRNA Translation: AAH29436.1 Different termination.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS34917.1 [Q8TCU3-1]

NCBI Reference Sequences

More...
RefSeqi
NP_620172.2, NM_138817.2 [Q8TCU3-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000297524; ENSP00000297524; ENSG00000164893 [Q8TCU3-1]
ENST00000419776; ENSP00000410982; ENSG00000164893 [Q8TCU3-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
157724

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:157724

UCSC genome browser

More...
UCSCi
uc003ydq.2, human [Q8TCU3-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ417661 mRNA Translation: CAD10393.1
AK055815 mRNA Translation: BAB71021.1
CH471060 Genomic DNA Translation: EAW91633.1
BC125165 mRNA Translation: AAI25166.1
BC125166 mRNA Translation: AAI25167.1
BC029436 mRNA Translation: AAH29436.1 Different termination.
CCDSiCCDS34917.1 [Q8TCU3-1]
RefSeqiNP_620172.2, NM_138817.2 [Q8TCU3-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi127618, 2 interactors
IntActiQ8TCU3, 2 interactors
MINTiQ8TCU3
STRINGi9606.ENSP00000297524

Protein family/group databases

TCDBi2.A.3.8.24, the amino acid-polyamine-organocation (apc) family

PTM databases

iPTMnetiQ8TCU3
PhosphoSitePlusiQ8TCU3

Polymorphism and mutation databases

BioMutaiSLC7A13
DMDMi74751412

Proteomic databases

PaxDbiQ8TCU3
PeptideAtlasiQ8TCU3
PRIDEiQ8TCU3
ProteomicsDBi74169 [Q8TCU3-1]
74170 [Q8TCU3-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
54555, 6 antibodies

Genome annotation databases

EnsembliENST00000297524; ENSP00000297524; ENSG00000164893 [Q8TCU3-1]
ENST00000419776; ENSP00000410982; ENSG00000164893 [Q8TCU3-2]
GeneIDi157724
KEGGihsa:157724
UCSCiuc003ydq.2, human [Q8TCU3-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
157724
DisGeNETi157724
EuPathDBiHostDB:ENSG00000164893.8

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SLC7A13
HGNCiHGNC:23092, SLC7A13
HPAiENSG00000164893, Tissue enriched (kidney)
MIMi617256, gene
neXtProtiNX_Q8TCU3
OpenTargetsiENSG00000164893
PharmGKBiPA134980828

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1287, Eukaryota
GeneTreeiENSGT00940000162798
HOGENOMiCLU_007946_3_0_1
InParanoidiQ8TCU3
KOiK13870
OMAiKSPNVHY
OrthoDBi621852at2759
PhylomeDBiQ8TCU3
TreeFamiTF313355

Enzyme and pathway databases

PathwayCommonsiQ8TCU3

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
157724, 4 hits in 868 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
SLC7A13, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
157724
PharosiQ8TCU3, Tdark

Protein Ontology

More...
PROi
PR:Q8TCU3
RNActiQ8TCU3, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000164893, Expressed in kidney epithelium and 36 other tissues
GenevisibleiQ8TCU3, HS

Family and domain databases

InterProiView protein in InterPro
IPR002293, AA/rel_permease1
PfamiView protein in Pfam
PF13520, AA_permease_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS7A13_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8TCU3
Secondary accession number(s): Q05C37, Q08AH9, Q96N84
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: June 1, 2002
Last modified: August 12, 2020
This is version 125 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. SIMILARITY comments
    Index of protein domains and families
  5. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
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